Click here to switch to the map view.

The map label for this gene is lgrD [H]

Identifier: 238027868

GI number: 238027868

Start: 2519499

End: 2524133

Strand: Reverse

Name: lgrD [H]

Synonym: bglu_1g23010

Alternate gene names: 238027868

Gene position: 2524133-2519499 (Counterclockwise)

Preceding gene: 238027869

Following gene: 238027867

Centisome position: 64.61

GC content: 71.93

Gene sequence:

>4635_bases
GTGAGCTCGATCGCATTCATCAATGAGCTGGCGGGACGGGGCATCGAGCTGTGGGCCCAGGACGGCAAGCTGCAATACAA
GGCGCCCAAGGGCGCCGTCACGCCGGCGCTGCTCGATCAGCTGAAGGCCGGCAAGGCCGCGCTGGTCGCGCTGCTGGAGC
AGTTCGCCGGCACCGCGGGCACCTATGCGCTGTCGTTCGCGCAGCAATCGCTGTGGTCGCTGCATCAGCTCAATCCGGAC
AGCGCCGCGTACAACGTCACCTATGCGACGCGTCTCGTCGACGACGTCGATGTCGCAGCGCTGCGTCGCTGCGTCGATTA
TCTGATCGCGCGGCACCCGGTGCTGCGAACCGCTTACCGCCTGATCGACGGCGAGCCGCGCCAGCAGATCGGCACCGACG
CGCGCGCGCAGTTCACGATCGACCGCGTGTTCGCGGCCGACGAAGGCGCCATTCGCCGATGGGTCGACGAGGAATCGAAT
CGCCCGTTCGACCTGACGCAGTCGCCGATCAGGCTGAAGCTGCTGCGCAACGAACACGACGGCGCGGACGCGATCCGCAC
CGTGCTGCTGTTGAACGTGCATCACATCGCCGCCGATTTCTGGTCGCTGGAGATCCTGCTCGGCGAGCTGCAGGCGCTGT
ATCGCCTGGCTCGCCTGGGCGAGCCGCTGAAGCTGCCGGCCCTGCCCGTGCAATACAAGGACTGCGTGGAGCACGAGCGC
CGCAGGCTCGATGCCGGCGAGGGCGAAGCGCTCGCCGCGTTCTGGCGGCGTGAGTTGCAGCACGGCTTTCCGGTCCTGAA
TCTGGCGACCGATCGCATCCGGCCGCCGCGCAAGACGGAGCGCGGCCGCGTGTTCGACCATCCGCTCGGTGCCGCGCTGT
CGGCGCGGGTGCGCGACACCGCGAAACGGTTGCGCGTGACGCCGTACATGCTGCTGCTGGCCGTCTATCAGCTGCAGCTC
CACCTGCACACCGGACAGACGCGGCTGATGATCGGCGCGCCGACCGCGGGGCGCAACGCGCCCGGCAGCGAGAACGTGGT
CGGTCATTTCGTGAACACCGTCGTGCTCGCGTGCGAGCTGCGGGCCGACGAGCCCTTCGACGACCTGTTACGACGCACGC
GCGAGATGATGCTGCGGGTGCTCGATCACCAGGACTTTCCGTTCCCGAAGCTGGTCGACGATCAGCGGCCGCCTCGCGAC
CCGAGCCGCTCGCCCATCTATCAGGTGATGTACAACTGGAACCAGGCGCGTGGCGATTTCGCCGCGTCGGGCGCTGCCGA
CGTTGCGCTCTATCGCGAGCGCCTCGCCGCGTCGAGCACCGGCACGCGCGGTGCAACGCACGACCTCACGCTCAACGTGC
AGGATCTCGGCGACGCGTACCTTTGCGCGTGGACCTTCAACACCGACCTGTTCGAGGAGGCGACGATCGCCCGCTTCGCG
AGCCAGTACGCCTACCTGGTCGAGCAGGTGGTGAACGACGCGCAACGGCCGCTGCATGGGTACCGGCTCGCCGCCGCCGA
GGCGGTACGCGAGCGGCTCGCCGCCGCCTGCGCACGCCGCCCGGCGCCGGCCGGGCCGGCCGAGCCGGTCGAGGCATCAC
GGGCGGTCTGGCGCTTCGACGAGCGCGAGATCCTGCACGGCGAGGTGGCCGGCGCGGTAGGCGCGCTGGCCGCGCGGTTC
GAGGCGCTCGGGATCGGTGCGGGTCAAGGCGTGGCGCTGCAACTGCCCGCCATCGCCGAGCGCGCGGCCGCGCTGCTCGC
GATCCGGGCAGTCGGCGCGCGTCTTGCCGCCTCGGCCGAACAGGCGGACGCGGTGTGCCGGGGCCGTGACGATGGGTGGG
CCGGCTGGGAGCCCGGGGCAATCGAGATAGCGCGCACCGGCCGGGCCGCGGCGCGGGACGGCGCCGGCGAGCCGGGCGCG
GCGGTCGATCCGTTGCTCGACGAGATCGGCGCGTGGCTGCGACTCGACGCCGACGCCACCGTGCTGATCGTGCGCGGCGC
CCATGCCGTGCTCGCGGCGGCGGCGCTCGCCAAGGTGGTGCTGACCGGCGGCCTCGCGCGGCTGTCCGGGCGGGCCGGGC
TGGACCGGCTCGCCGCGCGCGAGGCGGCGCTCGCGAAGCCCGCGTATGCCGAACTCGGCCGCTTGCTGGCGCATGCCCCG
TCGGTGCTGCTGCCCACGCTGTTGCTGCGGCAGGCCGATGCGCTCGGGCTTGCCCGCGCGCGCGCGCTTCTCGCCTATGG
CGACCATCCGCATCCGCTGGCGCGGCTCGTCGATGCCGGCCGCGCACCGGCGCTCGCGCATTTCGTGCCGCTGTGCGGCG
CCGACCTGCCGGCCGCGTGGTGCGCGTTCGTGCCCGGGGCGCACGGCTGGCGGCTCGCCGACCCCGCGCATCCGGCCCGT
GTCGCCGTCGTGCTCGGTGCGTCGGGGCACTTCGCGGACGACCGGCAGGCCGGCACGCTCCACTTCTTCGACGGCACGCG
GGCCGGCGCGTCGTCACCGTCCGGCGACGCGCCGCCGGACGGCACCGGCGTGGCGACCGGCCTGGCCGTGTCCTGCCGCG
ATGGCGAAATATGGTGCGCGGATCCGTCCGCGCGCGTCGCAGGCCATCGCGCCGCGCCCGTCGCGATCGGCGAGCTCGAG
CGTGCGATCTCGAGGGTCGACGGCATAGCCGACGTGGTATGCGTGAGCCTGGACGACGGCGCGTCCGCGCGGCTTGCCGC
CTACCTCGTGGCGCACGACGCCGGCTCCGACGGGCCGGCGCTCGAGCATGCGGTGCGCGCCGCGCTGAAGCAAGCCTTGC
CCGATGCGATGCACCCGGACGCCTATGCGCTGATCGAATCCTTGCCGCTCGACGCGGGCGGGGCGCTCGACGCGACCGGC
CTGCCGTCGCCGGCGGCCAACCCGGCGGCGTCCCGCGCCGCCGCGAGCGAGCTCGAGCGCCGGCTCGCGGCGATCTGGGC
CGAGGTGCTGGGGCAGCCGTCGGTCGGCGCCGACGACGACTTTTTCGCGCTCGGCGGCGATTCGATCCTGGCCGCGGTCA
TCGTGTCGCGGGCGGCGCTCGACGGCATGTATCTGAAGCCGCAGGACATTTTCCGGCACACCACCGTATCCGGTCTGGCG
ACGGCGGTGCGGCAGACGCCGGGGCTGGAAGTCGATCAGGGGCCCGTGCGGGGCGAAGCGGCGCTCGCGCCGGCCGCGCG
CTGGTTCGCCGAGCGCGTCGAGGTCGACCGGTCGCACTTCAATCAGGCCCTGCTGATTGCGCTGACCGAGGCGCCCGACC
CGGTCATCATGAACGAGGCGATCCGCATCGTCGCACGGCATCACGACATCCTGCGCTCGCGCTTCGTATCGCGCGACGGC
GCGCTGCACCATCTGTTCGAAGCCGACGAGGCACTCCAGGATGCGCGGTTCGCGGTCGTGCGCTGCGTCGACGGCGACGG
CCGGCACAGCGAGCGCGCGTGGGGCGACGCGATCGACGCGGCGCAGCGCGGCCTGGACATCGAAAGCGGCCGGCTGATGG
CGCTCAGATGGCTGGAAAGCACCGACCTGTCGAGCAGCCGGCTGCTGGTCGTGGTCCACCACCTGGCGATCGACGGGGTG
TCGTGGAGCATCCTGATGCAGGACCTGGCCGACGTCTATCTGCGCTTGCGCGCCCGCGAGGCCGCGGCGCTGCCGCTGAA
GACCACCTCCGCGAAGACCTGGATCGAGCAGTGGCACGCGCTCGCGCAGGGCGACGCACTCGACGAGGATCGGCGCTTCT
GGCGCGGGATCAAGACCCAGGTGCACGACACGCTTGCCGGCGCGAAGCGGATCGCGCTGATGCGTCACGGGCTGACGACG
ATCGTGCAGCATGCCTACCAGGAGGCGTCGCTCAGTTGCACGATCACGCTCGATGCCGAGCTGACTCACGCGTTTCGCAC
GGTGGCGCCGCGCGCCTACGGCACCGATGCGAACGACCTGCTCGTCGCGGCGCTGCACGCGGGTTTCCGGGCCTGGAGCG
GCTGCGATGCGCTGTTCGTGGACCTCGAGGGGCACGGCCGCGACGCGCTCGGCGACGCGGTCGACCTGAGCCGCAGCATC
GGCTGGTTCACGTCGATCTATCCGGTGCTGATCGACGCGCCGTTCGCCGCGGACGACCCGGCCGCGCTGATCAAGGCCGT
CAAGGCGCGCCTGCGCGAGATTCCGCGCAAGGGCGCGAGCTACGGCGTGCTGCGCTACCTCGATGCACGCACGCCGGAGG
ACGACGCGCTCGCCGCGTTTCCGGCGGCGCCCGTGCTGTTTACCTACCTCGGCCAGCTCGAGCAGCTCGCCGGCCAGTCG
CCGCTGTACGGCGGCGCGCCGGAGCCGGCGCCCGGCATCCGCAGCCCACGGCAGCGGCGCACCCACCTGCTCGACATGGT
CGCCTACGTGTCGCGCGGACGGCTGACCATCGAGTCGAGCTTCTTCGGCGTGCCCGGTGTCGACGAAAGCATCGGCTGCC
TGATGAGCCGCGTCGAGGAAGCGCTGACGACGCTGATTCGCCATTGCAGCGCGGACGGCGCCGGCGGACTGACGCCCGAC
GACGTGCCGCATCTCGACGTCGACCAGGACGATCTCGACGCGCTGCTGGACGAAATCGACGCACTCGACCGCTGA

Upstream 100 bases:

>100_bases
GCCGCGCGCCGGAAGCCGAGCCGCCGTCGCGCACCGCCGGCGGAATCGACGCGGTGTCCGGCGAGGCGACGTTCGGCATG
GAAATGGAAGGAGGAGAGCT

Downstream 100 bases:

>100_bases
CCGCACCAGGAATCCAAGATGACGAGAAACGTCGATACGATCTACCATCTCACGCCGCTGCAGCGCGGCATGCTGCATCA
CTCGCGGCTCGATCCCGCTT

Product: nonribosomal peptide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1544; Mature: 1543

Protein sequence:

>1544_residues
MSSIAFINELAGRGIELWAQDGKLQYKAPKGAVTPALLDQLKAGKAALVALLEQFAGTAGTYALSFAQQSLWSLHQLNPD
SAAYNVTYATRLVDDVDVAALRRCVDYLIARHPVLRTAYRLIDGEPRQQIGTDARAQFTIDRVFAADEGAIRRWVDEESN
RPFDLTQSPIRLKLLRNEHDGADAIRTVLLLNVHHIAADFWSLEILLGELQALYRLARLGEPLKLPALPVQYKDCVEHER
RRLDAGEGEALAAFWRRELQHGFPVLNLATDRIRPPRKTERGRVFDHPLGAALSARVRDTAKRLRVTPYMLLLAVYQLQL
HLHTGQTRLMIGAPTAGRNAPGSENVVGHFVNTVVLACELRADEPFDDLLRRTREMMLRVLDHQDFPFPKLVDDQRPPRD
PSRSPIYQVMYNWNQARGDFAASGAADVALYRERLAASSTGTRGATHDLTLNVQDLGDAYLCAWTFNTDLFEEATIARFA
SQYAYLVEQVVNDAQRPLHGYRLAAAEAVRERLAAACARRPAPAGPAEPVEASRAVWRFDEREILHGEVAGAVGALAARF
EALGIGAGQGVALQLPAIAERAAALLAIRAVGARLAASAEQADAVCRGRDDGWAGWEPGAIEIARTGRAAARDGAGEPGA
AVDPLLDEIGAWLRLDADATVLIVRGAHAVLAAAALAKVVLTGGLARLSGRAGLDRLAAREAALAKPAYAELGRLLAHAP
SVLLPTLLLRQADALGLARARALLAYGDHPHPLARLVDAGRAPALAHFVPLCGADLPAAWCAFVPGAHGWRLADPAHPAR
VAVVLGASGHFADDRQAGTLHFFDGTRAGASSPSGDAPPDGTGVATGLAVSCRDGEIWCADPSARVAGHRAAPVAIGELE
RAISRVDGIADVVCVSLDDGASARLAAYLVAHDAGSDGPALEHAVRAALKQALPDAMHPDAYALIESLPLDAGGALDATG
LPSPAANPAASRAAASELERRLAAIWAEVLGQPSVGADDDFFALGGDSILAAVIVSRAALDGMYLKPQDIFRHTTVSGLA
TAVRQTPGLEVDQGPVRGEAALAPAARWFAERVEVDRSHFNQALLIALTEAPDPVIMNEAIRIVARHHDILRSRFVSRDG
ALHHLFEADEALQDARFAVVRCVDGDGRHSERAWGDAIDAAQRGLDIESGRLMALRWLESTDLSSSRLLVVVHHLAIDGV
SWSILMQDLADVYLRLRAREAAALPLKTTSAKTWIEQWHALAQGDALDEDRRFWRGIKTQVHDTLAGAKRIALMRHGLTT
IVQHAYQEASLSCTITLDAELTHAFRTVAPRAYGTDANDLLVAALHAGFRAWSGCDALFVDLEGHGRDALGDAVDLSRSI
GWFTSIYPVLIDAPFAADDPAALIKAVKARLREIPRKGASYGVLRYLDARTPEDDALAAFPAAPVLFTYLGQLEQLAGQS
PLYGGAPEPAPGIRSPRQRRTHLLDMVAYVSRGRLTIESSFFGVPGVDESIGCLMSRVEEALTTLIRHCSADGAGGLTPD
DVPHLDVDQDDLDALLDEIDALDR

Sequences:

>Translated_1544_residues
MSSIAFINELAGRGIELWAQDGKLQYKAPKGAVTPALLDQLKAGKAALVALLEQFAGTAGTYALSFAQQSLWSLHQLNPD
SAAYNVTYATRLVDDVDVAALRRCVDYLIARHPVLRTAYRLIDGEPRQQIGTDARAQFTIDRVFAADEGAIRRWVDEESN
RPFDLTQSPIRLKLLRNEHDGADAIRTVLLLNVHHIAADFWSLEILLGELQALYRLARLGEPLKLPALPVQYKDCVEHER
RRLDAGEGEALAAFWRRELQHGFPVLNLATDRIRPPRKTERGRVFDHPLGAALSARVRDTAKRLRVTPYMLLLAVYQLQL
HLHTGQTRLMIGAPTAGRNAPGSENVVGHFVNTVVLACELRADEPFDDLLRRTREMMLRVLDHQDFPFPKLVDDQRPPRD
PSRSPIYQVMYNWNQARGDFAASGAADVALYRERLAASSTGTRGATHDLTLNVQDLGDAYLCAWTFNTDLFEEATIARFA
SQYAYLVEQVVNDAQRPLHGYRLAAAEAVRERLAAACARRPAPAGPAEPVEASRAVWRFDEREILHGEVAGAVGALAARF
EALGIGAGQGVALQLPAIAERAAALLAIRAVGARLAASAEQADAVCRGRDDGWAGWEPGAIEIARTGRAAARDGAGEPGA
AVDPLLDEIGAWLRLDADATVLIVRGAHAVLAAAALAKVVLTGGLARLSGRAGLDRLAAREAALAKPAYAELGRLLAHAP
SVLLPTLLLRQADALGLARARALLAYGDHPHPLARLVDAGRAPALAHFVPLCGADLPAAWCAFVPGAHGWRLADPAHPAR
VAVVLGASGHFADDRQAGTLHFFDGTRAGASSPSGDAPPDGTGVATGLAVSCRDGEIWCADPSARVAGHRAAPVAIGELE
RAISRVDGIADVVCVSLDDGASARLAAYLVAHDAGSDGPALEHAVRAALKQALPDAMHPDAYALIESLPLDAGGALDATG
LPSPAANPAASRAAASELERRLAAIWAEVLGQPSVGADDDFFALGGDSILAAVIVSRAALDGMYLKPQDIFRHTTVSGLA
TAVRQTPGLEVDQGPVRGEAALAPAARWFAERVEVDRSHFNQALLIALTEAPDPVIMNEAIRIVARHHDILRSRFVSRDG
ALHHLFEADEALQDARFAVVRCVDGDGRHSERAWGDAIDAAQRGLDIESGRLMALRWLESTDLSSSRLLVVVHHLAIDGV
SWSILMQDLADVYLRLRAREAAALPLKTTSAKTWIEQWHALAQGDALDEDRRFWRGIKTQVHDTLAGAKRIALMRHGLTT
IVQHAYQEASLSCTITLDAELTHAFRTVAPRAYGTDANDLLVAALHAGFRAWSGCDALFVDLEGHGRDALGDAVDLSRSI
GWFTSIYPVLIDAPFAADDPAALIKAVKARLREIPRKGASYGVLRYLDARTPEDDALAAFPAAPVLFTYLGQLEQLAGQS
PLYGGAPEPAPGIRSPRQRRTHLLDMVAYVSRGRLTIESSFFGVPGVDESIGCLMSRVEEALTTLIRHCSADGAGGLTPD
DVPHLDVDQDDLDALLDEIDALDR
>Mature_1543_residues
SSIAFINELAGRGIELWAQDGKLQYKAPKGAVTPALLDQLKAGKAALVALLEQFAGTAGTYALSFAQQSLWSLHQLNPDS
AAYNVTYATRLVDDVDVAALRRCVDYLIARHPVLRTAYRLIDGEPRQQIGTDARAQFTIDRVFAADEGAIRRWVDEESNR
PFDLTQSPIRLKLLRNEHDGADAIRTVLLLNVHHIAADFWSLEILLGELQALYRLARLGEPLKLPALPVQYKDCVEHERR
RLDAGEGEALAAFWRRELQHGFPVLNLATDRIRPPRKTERGRVFDHPLGAALSARVRDTAKRLRVTPYMLLLAVYQLQLH
LHTGQTRLMIGAPTAGRNAPGSENVVGHFVNTVVLACELRADEPFDDLLRRTREMMLRVLDHQDFPFPKLVDDQRPPRDP
SRSPIYQVMYNWNQARGDFAASGAADVALYRERLAASSTGTRGATHDLTLNVQDLGDAYLCAWTFNTDLFEEATIARFAS
QYAYLVEQVVNDAQRPLHGYRLAAAEAVRERLAAACARRPAPAGPAEPVEASRAVWRFDEREILHGEVAGAVGALAARFE
ALGIGAGQGVALQLPAIAERAAALLAIRAVGARLAASAEQADAVCRGRDDGWAGWEPGAIEIARTGRAAARDGAGEPGAA
VDPLLDEIGAWLRLDADATVLIVRGAHAVLAAAALAKVVLTGGLARLSGRAGLDRLAAREAALAKPAYAELGRLLAHAPS
VLLPTLLLRQADALGLARARALLAYGDHPHPLARLVDAGRAPALAHFVPLCGADLPAAWCAFVPGAHGWRLADPAHPARV
AVVLGASGHFADDRQAGTLHFFDGTRAGASSPSGDAPPDGTGVATGLAVSCRDGEIWCADPSARVAGHRAAPVAIGELER
AISRVDGIADVVCVSLDDGASARLAAYLVAHDAGSDGPALEHAVRAALKQALPDAMHPDAYALIESLPLDAGGALDATGL
PSPAANPAASRAAASELERRLAAIWAEVLGQPSVGADDDFFALGGDSILAAVIVSRAALDGMYLKPQDIFRHTTVSGLAT
AVRQTPGLEVDQGPVRGEAALAPAARWFAERVEVDRSHFNQALLIALTEAPDPVIMNEAIRIVARHHDILRSRFVSRDGA
LHHLFEADEALQDARFAVVRCVDGDGRHSERAWGDAIDAAQRGLDIESGRLMALRWLESTDLSSSRLLVVVHHLAIDGVS
WSILMQDLADVYLRLRAREAAALPLKTTSAKTWIEQWHALAQGDALDEDRRFWRGIKTQVHDTLAGAKRIALMRHGLTTI
VQHAYQEASLSCTITLDAELTHAFRTVAPRAYGTDANDLLVAALHAGFRAWSGCDALFVDLEGHGRDALGDAVDLSRSIG
WFTSIYPVLIDAPFAADDPAALIKAVKARLREIPRKGASYGVLRYLDARTPEDDALAAFPAAPVLFTYLGQLEQLAGQSP
LYGGAPEPAPGIRSPRQRRTHLLDMVAYVSRGRLTIESSFFGVPGVDESIGCLMSRVEEALTTLIRHCSADGAGGLTPDD
VPHLDVDQDDLDALLDEIDALDR

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 165978; Mature: 165847

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIAFINELAGRGIELWAQDGKLQYKAPKGAVTPALLDQLKAGKAALVALLEQFAGTAG
CCHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCH
TYALSFAQQSLWSLHQLNPDSAAYNVTYATRLVDDVDVAALRRCVDYLIARHPVLRTAYR
HHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LIDGEPRQQIGTDARAQFTIDRVFAADEGAIRRWVDEESNRPFDLTQSPIRLKLLRNEHD
HHCCCCHHHHCCCCHHEEEHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
GADAIRTVLLLNVHHIAADFWSLEILLGELQALYRLARLGEPLKLPALPVQYKDCVEHER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RRLDAGEGEALAAFWRRELQHGFPVLNLATDRIRPPRKTERGRVFDHPLGAALSARVRDT
HHCCCCCCHHHHHHHHHHHHHCCCEEEECHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AKRLRVTPYMLLLAVYQLQLHLHTGQTRLMIGAPTAGRNAPGSENVVGHFVNTVVLACEL
HHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEC
RADEPFDDLLRRTREMMLRVLDHQDFPFPKLVDDQRPPRDPSRSPIYQVMYNWNQARGDF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHCCCC
AASGAADVALYRERLAASSTGTRGATHDLTLNVQDLGDAYLCAWTFNTDLFEEATIARFA
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCEEEEEEEECCHHHHHHHHHHHH
SQYAYLVEQVVNDAQRPLHGYRLAAAEAVRERLAAACARRPAPAGPAEPVEASRAVWRFD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCC
EREILHGEVAGAVGALAARFEALGIGAGQGVALQLPAIAERAAALLAIRAVGARLAASAE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QADAVCRGRDDGWAGWEPGAIEIARTGRAAARDGAGEPGAAVDPLLDEIGAWLRLDADAT
HHHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHCCCEEEECCCCE
VLIVRGAHAVLAAAALAKVVLTGGLARLSGRAGLDRLAAREAALAKPAYAELGRLLAHAP
EEEEECHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
SVLLPTLLLRQADALGLARARALLAYGDHPHPLARLVDAGRAPALAHFVPLCGADLPAAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
CAFVPGAHGWRLADPAHPARVAVVLGASGHFADDRQAGTLHFFDGTRAGASSPSGDAPPD
HHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
GTGVATGLAVSCRDGEIWCADPSARVAGHRAAPVAIGELERAISRVDGIADVVCVSLDDG
CCCCCCCEEEEECCCEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEECCCC
ASARLAAYLVAHDAGSDGPALEHAVRAALKQALPDAMHPDAYALIESLPLDAGGALDATG
CCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
LPSPAANPAASRAAASELERRLAAIWAEVLGQPSVGADDDFFALGGDSILAAVIVSRAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
DGMYLKPQDIFRHTTVSGLATAVRQTPGLEVDQGPVRGEAALAPAARWFAERVEVDRSHF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
NQALLIALTEAPDPVIMNEAIRIVARHHDILRSRFVSRDGALHHLFEADEALQDARFAVV
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEE
RCVDGDGRHSERAWGDAIDAAQRGLDIESGRLMALRWLESTDLSSSRLLVVVHHLAIDGV
EEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHCCC
SWSILMQDLADVYLRLRAREAAALPLKTTSAKTWIEQWHALAQGDALDEDRRFWRGIKTQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VHDTLAGAKRIALMRHGLTTIVQHAYQEASLSCTITLDAELTHAFRTVAPRAYGTDANDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHH
LVAALHAGFRAWSGCDALFVDLEGHGRDALGDAVDLSRSIGWFTSIYPVLIDAPFAADDP
HHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
AALIKAVKARLREIPRKGASYGVLRYLDARTPEDDALAAFPAAPVLFTYLGQLEQLAGQS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCC
PLYGGAPEPAPGIRSPRQRRTHLLDMVAYVSRGRLTIESSFFGVPGVDESIGCLMSRVEE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHH
ALTTLIRHCSADGAGGLTPDDVPHLDVDQDDLDALLDEIDALDR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSIAFINELAGRGIELWAQDGKLQYKAPKGAVTPALLDQLKAGKAALVALLEQFAGTAG
CHHHHHHHHHCCCEEEEECCCEEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCH
TYALSFAQQSLWSLHQLNPDSAAYNVTYATRLVDDVDVAALRRCVDYLIARHPVLRTAYR
HHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LIDGEPRQQIGTDARAQFTIDRVFAADEGAIRRWVDEESNRPFDLTQSPIRLKLLRNEHD
HHCCCCHHHHCCCCHHEEEHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCC
GADAIRTVLLLNVHHIAADFWSLEILLGELQALYRLARLGEPLKLPALPVQYKDCVEHER
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
RRLDAGEGEALAAFWRRELQHGFPVLNLATDRIRPPRKTERGRVFDHPLGAALSARVRDT
HHCCCCCCHHHHHHHHHHHHHCCCEEEECHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AKRLRVTPYMLLLAVYQLQLHLHTGQTRLMIGAPTAGRNAPGSENVVGHFVNTVVLACEL
HHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEC
RADEPFDDLLRRTREMMLRVLDHQDFPFPKLVDDQRPPRDPSRSPIYQVMYNWNQARGDF
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHCCCC
AASGAADVALYRERLAASSTGTRGATHDLTLNVQDLGDAYLCAWTFNTDLFEEATIARFA
CCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCEEEEEEEECCHHHHHHHHHHHH
SQYAYLVEQVVNDAQRPLHGYRLAAAEAVRERLAAACARRPAPAGPAEPVEASRAVWRFD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCC
EREILHGEVAGAVGALAARFEALGIGAGQGVALQLPAIAERAAALLAIRAVGARLAASAE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QADAVCRGRDDGWAGWEPGAIEIARTGRAAARDGAGEPGAAVDPLLDEIGAWLRLDADAT
HHHHHHCCCCCCCCCCCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHCCCEEEECCCCE
VLIVRGAHAVLAAAALAKVVLTGGLARLSGRAGLDRLAAREAALAKPAYAELGRLLAHAP
EEEEECHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
SVLLPTLLLRQADALGLARARALLAYGDHPHPLARLVDAGRAPALAHFVPLCGADLPAAW
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCHHHH
CAFVPGAHGWRLADPAHPARVAVVLGASGHFADDRQAGTLHFFDGTRAGASSPSGDAPPD
HHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
GTGVATGLAVSCRDGEIWCADPSARVAGHRAAPVAIGELERAISRVDGIADVVCVSLDDG
CCCCCCCEEEEECCCEEEECCCCHHHCCCCCCCHHHHHHHHHHHHHCCHHHEEEEECCCC
ASARLAAYLVAHDAGSDGPALEHAVRAALKQALPDAMHPDAYALIESLPLDAGGALDATG
CCHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
LPSPAANPAASRAAASELERRLAAIWAEVLGQPSVGADDDFFALGGDSILAAVIVSRAAL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHH
DGMYLKPQDIFRHTTVSGLATAVRQTPGLEVDQGPVRGEAALAPAARWFAERVEVDRSHF
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
NQALLIALTEAPDPVIMNEAIRIVARHHDILRSRFVSRDGALHHLFEADEALQDARFAVV
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEE
RCVDGDGRHSERAWGDAIDAAQRGLDIESGRLMALRWLESTDLSSSRLLVVVHHLAIDGV
EEECCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCEEEEEHHHHCCC
SWSILMQDLADVYLRLRAREAAALPLKTTSAKTWIEQWHALAQGDALDEDRRFWRGIKTQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VHDTLAGAKRIALMRHGLTTIVQHAYQEASLSCTITLDAELTHAFRTVAPRAYGTDANDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHH
LVAALHAGFRAWSGCDALFVDLEGHGRDALGDAVDLSRSIGWFTSIYPVLIDAPFAADDP
HHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCH
AALIKAVKARLREIPRKGASYGVLRYLDARTPEDDALAAFPAAPVLFTYLGQLEQLAGQS
HHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCC
PLYGGAPEPAPGIRSPRQRRTHLLDMVAYVSRGRLTIESSFFGVPGVDESIGCLMSRVEE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHH
ALTTLIRHCSADGAGGLTPDDVPHLDVDQDDLDALLDEIDALDR
HHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA