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The map label for this gene is tcp [H]

Identifier: 238027819

GI number: 238027819

Start: 2452462

End: 2454147

Strand: Reverse

Name: tcp [H]

Synonym: bglu_1g22500

Alternate gene names: 238027819

Gene position: 2454147-2452462 (Counterclockwise)

Preceding gene: 238027825

Following gene: 238027818

Centisome position: 62.82

GC content: 59.37

Gene sequence:

>1686_bases
ATGAAAAATCTGAAAATTGGTACTCGTCTCGCACTTTGCTTCGGTGCCTTGATGGTTCTCGTGGTCATCACCGCACTGAT
GGGAATTGGAAGAATTTCAGCGCTCAGCGCGACCACCACGCAGATCACCGAGAATATTTACGTCAAGGCGGCGGCAACGT
CTAAGCTCGGCTACGCCGTGCTGGATATGAGTCGTCTTGCCAGAAACATGATTCTCTCCAATGACGCCGAGAGTCTGCGA
GGTTTCAAGCGAGATTACGATGCGCGCAAGGCGGAGGTTTCCCAACTGATGGCCACCTTGGACGCAAATATCCACACGGG
AGCCGACCGGACATTGTTCGATGCCGTACAAGCCGCCAGTGAGCAGTTTTTCCCGTTCATGGACGATGTGGTTGCCTTGG
GTATGCAGAACCAGGACAGTGAAGCCGCCAAGCTGCTATTCGGACCGCGATATGCGACGCAGGGCGTTTACCTGAAAACG
CTGAAGGCGCTCACGCAATTCCAGGAGGCGCGGATGCACGAAGGTGGGCAGTTCGCCATGGCGGTGCGTGCGCAGTCCAT
CATATTGATGGTGGTGCTCTCGCTGCTGGCTGTTGCTATCGGTTTCGGTCTTGCATGGTACGTCACCCGCAGTGTGACCC
GGCCGATCTCGGAATCAGTCGAGGTGGCGAAGCGGGTGGCCGCTAATGATCTGAGTCAGGCGATTGTGGTGGACCGCCGC
GACGAAGCCGGGCAACTGCTCGAGGCACTGCGCATCATGCAGCACAGTCTTGCCGCAACCGTCGTCTCGGTGCGGACCAA
CGCCGAGAGCGTCGCCACGGCAAGCGCGCAGATTGCACAAGGCAATACCGATCTGAGTCGACGCACCGAAGAGCAGGCTG
CCTCGCTGGAGGAAACCGCCGCGAGCATGGAAGAATTGACCGCGACGGTCAAGCAGAACACCGAGAATGCCCAGCAAGGC
AATCAGTTGGCCAATCGTGCCTCGGAAATTGCAGCAAGGGGTGACGCGGTCGTCGATCGTGTCGTGGGAACCATGGCGCA
GATATCGACGAGTTCCACCCAAATCTCCGGCATCATCACCGTCATCGAGAGCATTGCATTCCAGACCAATATCCTTGCGC
TCAATGCAGCCGTCGAAGCCGCCAGAGCCGGGGAACAAGGTCGTGGATTCGCCGTTGTCGCCGCAGAAGTGCGCACCTTG
GCCCAACGCAGTGCATCGGCTGCCAAGGAGATCAAGGATCTGATCACGGGCTCGTCGGCTCATGTGGAAAGCGGGTCGCT
GCTGGTGAGCGAGGCGGGAACGACGATGAAAGAGATCATGCAGGCGGTGCGCCGCGTCAAGGATCTGATGGAAGAGATCT
CGGCGGCCTCGCTTGAGCAACGCACCGGTATCGAGCAGGTCAACCAAGCCGTCTCGCAGATGGATGAAGTCACGCAACAG
AACGCCGCGTTGGTTGAGGAGGCGTCAGCGGCAGCGCAATCGATGGCGGTACAGTCGACCGAATTGCGTCGTTCCATGGG
GATGTTCGTACTCGCGACGGAAGCAACGGGGATGGCGAACCTCGCGCCGGTCGAGGCCGATGCCTTGCGGCCAGCCCACC
GCACGGATGCCGTACCGAGCCGAAGCGGTCGACCGATGCTGGCCAAGCGAACCGAACCGAGTGACGTCAGTTGGCAGACG
TTCTGA

Upstream 100 bases:

>100_bases
CGTCAGTCTCTGGATCGACGACGAGCTGTTCGTCAGCCACGACGCTTACCTTTTACGAAAACTCGCGGCGCTACCTCGTA
CGTAACACTTCGCATGCCTT

Downstream 100 bases:

>100_bases
AACTGGCTTCGGCCATGTAATCGACGCGCCCGACATGCGGCTCGCTTAGCTGGCGCCGCCACTCGGGGCGACCTGGCGCG
CAAGGTGCTCGACGATGCGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKNLKIGTRLALCFGALMVLVVITALMGIGRISALSATTTQITENIYVKAAATSKLGYAVLDMSRLARNMILSNDAESLR
GFKRDYDARKAEVSQLMATLDANIHTGADRTLFDAVQAASEQFFPFMDDVVALGMQNQDSEAAKLLFGPRYATQGVYLKT
LKALTQFQEARMHEGGQFAMAVRAQSIILMVVLSLLAVAIGFGLAWYVTRSVTRPISESVEVAKRVAANDLSQAIVVDRR
DEAGQLLEALRIMQHSLAATVVSVRTNAESVATASAQIAQGNTDLSRRTEEQAASLEETAASMEELTATVKQNTENAQQG
NQLANRASEIAARGDAVVDRVVGTMAQISTSSTQISGIITVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTL
AQRSASAAKEIKDLITGSSAHVESGSLLVSEAGTTMKEIMQAVRRVKDLMEEISAASLEQRTGIEQVNQAVSQMDEVTQQ
NAALVEEASAAAQSMAVQSTELRRSMGMFVLATEATGMANLAPVEADALRPAHRTDAVPSRSGRPMLAKRTEPSDVSWQT
F

Sequences:

>Translated_561_residues
MKNLKIGTRLALCFGALMVLVVITALMGIGRISALSATTTQITENIYVKAAATSKLGYAVLDMSRLARNMILSNDAESLR
GFKRDYDARKAEVSQLMATLDANIHTGADRTLFDAVQAASEQFFPFMDDVVALGMQNQDSEAAKLLFGPRYATQGVYLKT
LKALTQFQEARMHEGGQFAMAVRAQSIILMVVLSLLAVAIGFGLAWYVTRSVTRPISESVEVAKRVAANDLSQAIVVDRR
DEAGQLLEALRIMQHSLAATVVSVRTNAESVATASAQIAQGNTDLSRRTEEQAASLEETAASMEELTATVKQNTENAQQG
NQLANRASEIAARGDAVVDRVVGTMAQISTSSTQISGIITVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTL
AQRSASAAKEIKDLITGSSAHVESGSLLVSEAGTTMKEIMQAVRRVKDLMEEISAASLEQRTGIEQVNQAVSQMDEVTQQ
NAALVEEASAAAQSMAVQSTELRRSMGMFVLATEATGMANLAPVEADALRPAHRTDAVPSRSGRPMLAKRTEPSDVSWQT
F
>Mature_561_residues
MKNLKIGTRLALCFGALMVLVVITALMGIGRISALSATTTQITENIYVKAAATSKLGYAVLDMSRLARNMILSNDAESLR
GFKRDYDARKAEVSQLMATLDANIHTGADRTLFDAVQAASEQFFPFMDDVVALGMQNQDSEAAKLLFGPRYATQGVYLKT
LKALTQFQEARMHEGGQFAMAVRAQSIILMVVLSLLAVAIGFGLAWYVTRSVTRPISESVEVAKRVAANDLSQAIVVDRR
DEAGQLLEALRIMQHSLAATVVSVRTNAESVATASAQIAQGNTDLSRRTEEQAASLEETAASMEELTATVKQNTENAQQG
NQLANRASEIAARGDAVVDRVVGTMAQISTSSTQISGIITVIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTL
AQRSASAAKEIKDLITGSSAHVESGSLLVSEAGTTMKEIMQAVRRVKDLMEEISAASLEQRTGIEQVNQAVSQMDEVTQQ
NAALVEEASAAAQSMAVQSTELRRSMGMFVLATEATGMANLAPVEADALRPAHRTDAVPSRSGRPMLAKRTEPSDVSWQT
F

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=57.0469798657718, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1788195, Length=357, Percent_Identity=50.9803921568627, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI1787690, Length=469, Percent_Identity=43.2835820895522, Blast_Score=291, Evalue=9e-80,
Organism=Escherichia coli, GI1788194, Length=331, Percent_Identity=50.4531722054381, Blast_Score=281, Evalue=1e-76,
Organism=Escherichia coli, GI1789453, Length=311, Percent_Identity=39.5498392282958, Blast_Score=193, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59951; Mature: 59951

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLKIGTRLALCFGALMVLVVITALMGIGRISALSATTTQITENIYVKAAATSKLGYAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCCHHHHHH
LDMSRLARNMILSNDAESLRGFKRDYDARKAEVSQLMATLDANIHTGADRTLFDAVQAAS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
EQFFPFMDDVVALGMQNQDSEAAKLLFGPRYATQGVYLKTLKALTQFQEARMHEGGQFAM
HHCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCEEH
AVRAQSIILMVVLSLLAVAIGFGLAWYVTRSVTRPISESVEVAKRVAANDLSQAIVVDRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
DEAGQLLEALRIMQHSLAATVVSVRTNAESVATASAQIAQGNTDLSRRTEEQAASLEETA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ASMEELTATVKQNTENAQQGNQLANRASEIAARGDAVVDRVVGTMAQISTSSTQISGIIT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHH
VIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRSASAAKEIKDLITGSSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HVESGSLLVSEAGTTMKEIMQAVRRVKDLMEEISAASLEQRTGIEQVNQAVSQMDEVTQQ
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NAALVEEASAAAQSMAVQSTELRRSMGMFVLATEATGMANLAPVEADALRPAHRTDAVPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCHHCCCCCC
RSGRPMLAKRTEPSDVSWQTF
CCCCCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MKNLKIGTRLALCFGALMVLVVITALMGIGRISALSATTTQITENIYVKAAATSKLGYAV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEEECCCHHHHHH
LDMSRLARNMILSNDAESLRGFKRDYDARKAEVSQLMATLDANIHTGADRTLFDAVQAAS
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
EQFFPFMDDVVALGMQNQDSEAAKLLFGPRYATQGVYLKTLKALTQFQEARMHEGGQFAM
HHCCHHHHHHHHHCCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCEEH
AVRAQSIILMVVLSLLAVAIGFGLAWYVTRSVTRPISESVEVAKRVAANDLSQAIVVDRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
DEAGQLLEALRIMQHSLAATVVSVRTNAESVATASAQIAQGNTDLSRRTEEQAASLEETA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ASMEELTATVKQNTENAQQGNQLANRASEIAARGDAVVDRVVGTMAQISTSSTQISGIIT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHH
VIESIAFQTNILALNAAVEAARAGEQGRGFAVVAAEVRTLAQRSASAAKEIKDLITGSSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HVESGSLLVSEAGTTMKEIMQAVRRVKDLMEEISAASLEQRTGIEQVNQAVSQMDEVTQQ
CCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
NAALVEEASAAAQSMAVQSTELRRSMGMFVLATEATGMANLAPVEADALRPAHRTDAVPS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCCCHHCCCCCC
RSGRPMLAKRTEPSDVSWQTF
CCCCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]