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The map label for this gene is cobO [H]

Identifier: 238027452

GI number: 238027452

Start: 2033298

End: 2033900

Strand: Direct

Name: cobO [H]

Synonym: bglu_1g18550

Alternate gene names: 238027452

Gene position: 2033298-2033900 (Clockwise)

Preceding gene: 238027451

Following gene: 238027453

Centisome position: 52.05

GC content: 67.83

Gene sequence:

>603_bases
ATGAAAACCGATCCCGAATCGCATCAGCGCATGACCGAACGCCGCCGCGCCGGCCACGAGAAGAAGCAGGCTGCGGCCAC
CGTCGAGAAGGGGCTGCTGATCGTCAACACCGGCAACGGCAAGGGCAAGACCACGGCCGCCTTCGGCATGGCGGTGCGCG
TGCTCGGCCATGGCATGCGGCTCGGCGTGGTGCAGTTCATCAAGGGCGCCCTGCACACCGCCGAGCGCGACCTCCTGGAC
ACCTTCGCGCAATGCGATTTCGTCACGATGGGCGACGGCTACACCTGGAACACGCAGAACCGCGACGCCGACATCGCCAC
CGCGCGCAAGGGCTGGGACGCGGCGCGCCGCATGATCGAGAGCGGCGAATATCAGATGGTGATCCTCGACGAGCTGAACA
CCGTGCTCAAGTACGAGTACCTGCCGCTCGACGAGGTGCTGGCCGTGCTGGCCGCGCGCGCGCCGATGCTGCACGTGGTG
ATCACGGGCCGCCACGCGCCGGACGCGCTCGTGGAGGCCGCCGATCTCGTCACCGAGATGCGGCTCGTCAAGCACCCGTA
CCGCGAGCAGCACGTGAAGGCGCAGCGCGGCGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
CTGGTGACGAAGACGGTCGTCGACGGCGTGACCGCCGCGATCGCCGGACCGCTCTGAGCCTCGCGCGCCCTCCCCCCAAT
TTCCGCACTCAGGAGACCCG

Downstream 100 bases:

>100_bases
TGACGGCGGCCGGCATGCCAGCCTGTCCCGCGCTGCTGATCGGCGCGAGCGGGTCCGGCCAGGGCAAGACCTCCGTGACC
GCCGGGCTCGCGCGGCTGCA

Product: cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKTDPESHQRMTERRRAGHEKKQAAATVEKGLLIVNTGNGKGKTTAAFGMAVRVLGHGMRLGVVQFIKGALHTAERDLLD
TFAQCDFVTMGDGYTWNTQNRDADIATARKGWDAARRMIESGEYQMVILDELNTVLKYEYLPLDEVLAVLAARAPMLHVV
ITGRHAPDALVEAADLVTEMRLVKHPYREQHVKAQRGVEF

Sequences:

>Translated_200_residues
MKTDPESHQRMTERRRAGHEKKQAAATVEKGLLIVNTGNGKGKTTAAFGMAVRVLGHGMRLGVVQFIKGALHTAERDLLD
TFAQCDFVTMGDGYTWNTQNRDADIATARKGWDAARRMIESGEYQMVILDELNTVLKYEYLPLDEVLAVLAARAPMLHVV
ITGRHAPDALVEAADLVTEMRLVKHPYREQHVKAQRGVEF
>Mature_200_residues
MKTDPESHQRMTERRRAGHEKKQAAATVEKGLLIVNTGNGKGKTTAAFGMAVRVLGHGMRLGVVQFIKGALHTAERDLLD
TFAQCDFVTMGDGYTWNTQNRDADIATARKGWDAARRMIESGEYQMVILDELNTVLKYEYLPLDEVLAVLAARAPMLHVV
ITGRHAPDALVEAADLVTEMRLVKHPYREQHVKAQRGVEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=45.6410256410256, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22312; Mature: 22312

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDPESHQRMTERRRAGHEKKQAAATVEKGLLIVNTGNGKGKTTAAFGMAVRVLGHGMR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHH
LGVVQFIKGALHTAERDLLDTFAQCDFVTMGDGYTWNTQNRDADIATARKGWDAARRMIE
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCHHHHHCCHHHHHHHHH
SGEYQMVILDELNTVLKYEYLPLDEVLAVLAARAPMLHVVITGRHAPDALVEAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYREQHVKAQRGVEF
HHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTDPESHQRMTERRRAGHEKKQAAATVEKGLLIVNTGNGKGKTTAAFGMAVRVLGHGMR
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHCCHH
LGVVQFIKGALHTAERDLLDTFAQCDFVTMGDGYTWNTQNRDADIATARKGWDAARRMIE
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCCCCCHHHHHCCHHHHHHHHH
SGEYQMVILDELNTVLKYEYLPLDEVLAVLAARAPMLHVVITGRHAPDALVEAADLVTEM
CCCEEEEEHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHH
RLVKHPYREQHVKAQRGVEF
HHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]