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The map label for this gene is cobI [H]

Identifier: 238027442

GI number: 238027442

Start: 2018785

End: 2019555

Strand: Direct

Name: cobI [H]

Synonym: bglu_1g18450

Alternate gene names: 238027442

Gene position: 2018785-2019555 (Clockwise)

Preceding gene: 238027441

Following gene: 238027443

Centisome position: 51.68

GC content: 70.17

Gene sequence:

>771_bases
ATGAAGCTGCCGTCGGATTCGCTCCCGCGCGCACGCGCCGGCATCGCCCGCGGCCGGCTGTTCGGCATCGGCGTCGGCCC
CGGCGACCCCGAGCTACTGACCCTGAAGGCCGTGCGCCTGCTGCGCGCCGCGCCGGTGGTGGCCTACTTCGTCGCCAAGG
GCAAGAAAGGCAATGCCTACGGCATCGTCGAGGCGCACCTGGGCGAGACGCAGCATCAGCTGCCGCTGGTCTATCCGGTC
ACCACCGAGGCGCTCGCGCCGCCGCTCAGCTACGAGCGCATCATCGCCGACTTCTACGACACCGCCGCCGAGGTGGTGGC
CGGGCACCTCGACGCGGGCCGCGACGTAGCCGTGATCTGCGAGGGCGATCCGCTCTTCTACGGCTCCTACATGTATCTGC
ACGACCGGCTCGCGCAGCGCTACGAGACGGAGGTGGTGCCCGGCGTGTGCTCGATGCTCGGCGGCGCGGCCGTGCTCGGC
GTGCCGCTCGTCTACCGCAACCAGACGCTGTCGGTGCTCTCGGGCGTGCTGCCCGCCGACCAGCTGCGCGCGCGGCTCGA
GCAGGCCGACGCGGCCGTGGTGATGAAGCTCGGCCGCAATTTCGACAAGGTGCGCCGCGTGCTGGAGGAACTCGGGCTCG
CCAAGCGCGCGCTGTACGTCGAACGCGCGACCATGACGAACCAGCGCATCGTGCCGCTCGCCGAGGTCGACCCGATGGCC
TCGCCGTATTTTTCGCTGCTCGTCGTGCCGGGGGAAAAATGGCAAGGCTGA

Upstream 100 bases:

>100_bases
CGGCCGACAGCCGCGGCGTGCCGTTCGTGGCCGTGGCGGGCCGGCGCGGCGGCAGCGCGATGGCCGCCGCCGCCGTCAAC
GCGCTGGCTGCGGAGGTCGA

Downstream 100 bases:

>100_bases
ACGTCGCGCCGGCGATCGTCGTGCTCGGCGCCGGCGCGCTGCCGGTGGCCGAGCGGATTCGCGCGCGCTACGCGGGCGCC
ACCCTCCACGCGCTCGCGGG

Product: precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKLPSDSLPRARAGIARGRLFGIGVGPGDPELLTLKAVRLLRAAPVVAYFVAKGKKGNAYGIVEAHLGETQHQLPLVYPV
TTEALAPPLSYERIIADFYDTAAEVVAGHLDAGRDVAVICEGDPLFYGSYMYLHDRLAQRYETEVVPGVCSMLGGAAVLG
VPLVYRNQTLSVLSGVLPADQLRARLEQADAAVVMKLGRNFDKVRRVLEELGLAKRALYVERATMTNQRIVPLAEVDPMA
SPYFSLLVVPGEKWQG

Sequences:

>Translated_256_residues
MKLPSDSLPRARAGIARGRLFGIGVGPGDPELLTLKAVRLLRAAPVVAYFVAKGKKGNAYGIVEAHLGETQHQLPLVYPV
TTEALAPPLSYERIIADFYDTAAEVVAGHLDAGRDVAVICEGDPLFYGSYMYLHDRLAQRYETEVVPGVCSMLGGAAVLG
VPLVYRNQTLSVLSGVLPADQLRARLEQADAAVVMKLGRNFDKVRRVLEELGLAKRALYVERATMTNQRIVPLAEVDPMA
SPYFSLLVVPGEKWQG
>Mature_256_residues
MKLPSDSLPRARAGIARGRLFGIGVGPGDPELLTLKAVRLLRAAPVVAYFVAKGKKGNAYGIVEAHLGETQHQLPLVYPV
TTEALAPPLSYERIIADFYDTAAEVVAGHLDAGRDVAVICEGDPLFYGSYMYLHDRLAQRYETEVVPGVCSMLGGAAVLG
VPLVYRNQTLSVLSGVLPADQLRARLEQADAAVVMKLGRNFDKVRRVLEELGLAKRALYVERATMTNQRIVPLAEVDPMA
SPYFSLLVVPGEKWQG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27770; Mature: 27770

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPSDSLPRARAGIARGRLFGIGVGPGDPELLTLKAVRLLRAAPVVAYFVAKGKKGNAY
CCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GIVEAHLGETQHQLPLVYPVTTEALAPPLSYERIIADFYDTAAEVVAGHLDAGRDVAVIC
EEEEECCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDPLFYGSYMYLHDRLAQRYETEVVPGVCSMLGGAAVLGVPLVYRNQTLSVLSGVLPAD
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEECCCHHHHHHCCCCHH
QLRARLEQADAAVVMKLGRNFDKVRRVLEELGLAKRALYVERATMTNQRIVPLAEVDPMA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHCCCCCC
SPYFSLLVVPGEKWQG
CCCEEEEEECCCCCCC
>Mature Secondary Structure
MKLPSDSLPRARAGIARGRLFGIGVGPGDPELLTLKAVRLLRAAPVVAYFVAKGKKGNAY
CCCCCCCCCHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GIVEAHLGETQHQLPLVYPVTTEALAPPLSYERIIADFYDTAAEVVAGHLDAGRDVAVIC
EEEEECCCCCCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
EGDPLFYGSYMYLHDRLAQRYETEVVPGVCSMLGGAAVLGVPLVYRNQTLSVLSGVLPAD
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEECCCHHHHHHCCCCHH
QLRARLEQADAAVVMKLGRNFDKVRRVLEELGLAKRALYVERATMTNQRIVPLAEVDPMA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHCCCCCC
SPYFSLLVVPGEKWQG
CCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]