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The map label for this gene is moaE [H]

Identifier: 238027041

GI number: 238027041

Start: 1562041

End: 1562514

Strand: Direct

Name: moaE [H]

Synonym: bglu_1g14190

Alternate gene names: 238027041

Gene position: 1562041-1562514 (Clockwise)

Preceding gene: 238027040

Following gene: 238027042

Centisome position: 39.99

GC content: 71.31

Gene sequence:

>474_bases
ATGGCCACGATCCGGGTGCAGACCGACGATTTCGAGGTGGGCGCGGAGCTGGCCGCGCTGCGCGCGCGCAATCCGCGCAT
CGGCGCGGTGGCCTGCTTCATCGGCACGGTGCGCGACCTCAACGAGGGCGATTCGGTCGCCGCGCTCGAACTCGAGCACT
ATCCGGGCATGACCGAGAAGGCGCTCGAGGCGATCGCGGCCGACGCGATCGCGCGCTGGCCCGGCATCGACGTGACGATC
GTGCATCGCGTCGGCCGGCTGCTGCCGCTCGACCAGATCGTGCTGGTGGCGACGGTGTCCGCTCATCGCGGCGAGGCCTT
CGCCTCCTGCGAGTTCGTGATGGACTACCTGAAGACGCAGGCGCCGTTCTGGAAGAAGGAGACCACCCCGGCCGGCGAGC
GCTGGGTCGACGCGCGCAGCAGCGACGATGCCGCGCTCGCGCGCTGGGGCCTCGCCTCCGGCAACGCGCGCTGA

Upstream 100 bases:

>100_bases
CATGGCCTGCAATCATGTGATGACCGACGCGGATACGCGCCTTACCGACGGCTGCGAAGTCGCGTTCTTTCCGCCGGTGA
CGGGCGGCTGAGGAGGCGCG

Downstream 100 bases:

>100_bases
GCGGCGCGCCTCCGGCCTCGCCGCGGCCTCCCGCCCCGAGTCTTGTCTCGAGTCCTGCCCCGATTTCCGCCGCCACCGCG
TTGTCATCCATGACCGATTC

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MATIRVQTDDFEVGAELAALRARNPRIGAVACFIGTVRDLNEGDSVAALELEHYPGMTEKALEAIAADAIARWPGIDVTI
VHRVGRLLPLDQIVLVATVSAHRGEAFASCEFVMDYLKTQAPFWKKETTPAGERWVDARSSDDAALARWGLASGNAR

Sequences:

>Translated_157_residues
MATIRVQTDDFEVGAELAALRARNPRIGAVACFIGTVRDLNEGDSVAALELEHYPGMTEKALEAIAADAIARWPGIDVTI
VHRVGRLLPLDQIVLVATVSAHRGEAFASCEFVMDYLKTQAPFWKKETTPAGERWVDARSSDDAALARWGLASGNAR
>Mature_156_residues
ATIRVQTDDFEVGAELAALRARNPRIGAVACFIGTVRDLNEGDSVAALELEHYPGMTEKALEAIAADAIARWPGIDVTIV
HRVGRLLPLDQIVLVATVSAHRGEAFASCEFVMDYLKTQAPFWKKETTPAGERWVDARSSDDAALARWGLASGNAR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=34.5132743362832, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787003, Length=146, Percent_Identity=56.1643835616438, Blast_Score=161, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356259, Length=101, Percent_Identity=38.6138613861386, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17019; Mature: 16888

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIRVQTDDFEVGAELAALRARNPRIGAVACFIGTVRDLNEGDSVAALELEHYPGMTEK
CCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALEAIAADAIARWPGIDVTIVHRVGRLLPLDQIVLVATVSAHRGEAFASCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHC
APFWKKETTPAGERWVDARSSDDAALARWGLASGNAR
CCCCCCCCCCCCHHEECCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATIRVQTDDFEVGAELAALRARNPRIGAVACFIGTVRDLNEGDSVAALELEHYPGMTEK
CEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHH
ALEAIAADAIARWPGIDVTIVHRVGRLLPLDQIVLVATVSAHRGEAFASCEFVMDYLKTQ
HHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHC
APFWKKETTPAGERWVDARSSDDAALARWGLASGNAR
CCCCCCCCCCCCHHEECCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]