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The map label for this gene is moeA [H]

Identifier: 238027039

GI number: 238027039

Start: 1560483

End: 1561754

Strand: Direct

Name: moeA [H]

Synonym: bglu_1g14170

Alternate gene names: 238027039

Gene position: 1560483-1561754 (Clockwise)

Preceding gene: 238027038

Following gene: 238027040

Centisome position: 39.95

GC content: 74.14

Gene sequence:

>1272_bases
ATGTCCACCCCCGCATCCCAGGCGCCGCGCGCGCCGCTGCTGTCGACCGCCGAGGCGCTCGCCGCGCTGCTCGGCGCCGC
CGCGCCGCTCGCGCAGACCGAAACCGTGCCGACGCTCGACGCGCTCGGCCGCGTGCTGGCCGTCGACGTGGTGTCGCCGC
TCGACGTGCCGCCGATGGCGATCAGCGCGATGGACGGCTACGCGGTGCGCGTCGCCGACCTGACCCAGGGCACGCGCCGG
CTGCCCGTCTCGCAGCGGATTCCCGCCGGTCACGCGGCCGCGCCGCTGGCGGCCGGCACCGCCGCGCGCATCTTCACCGG
CGCGCCGCTGCCGCCCGGCGCCGATGCCGTGGTGATGCAGGAGCAGGCCGAGGCCGCGGGCGAGGCGGTCGACATCCTGC
ATACGCCGAAGGCCGGTGAATGGATCACGGCGCAGGGCGCCGACATCCGGCGCGGCACGGTGATCCTGCCGGCCGGCACG
CGGCTCGCGCCGCAGGCGCTCGGCCTGGCCGCCTCGGTCGGCTGCGCGCATCTGACGGTGCGGCGCCGCGTGAAGGTGGC
GGTGTTCTTTACCGGCGACGAGCTGACCATGCCGGGCGAGCCGCTCGCGCCGGGCGCGATCTACAACTCGAACCGCTTCA
CGCTGCGCGGGCTGCTCGAACGCTTCGGCTGCGAGGTCAGCGATTTCGGCATCGTGCCCGACTCGCTCGACGCGACACGC
GCCACGCTGCGCGAGGCCGCGCGGGATCACGACCTGATCGTGACGAGCGGCGGCGTGTCGGTGGGCGAGGAGGACCACGT
GAAGCCGGCCGTCGAGGCCGAGGGGCGCCTCACGCTCTGGCAGATCGCGATGAAGCCGGGCAAGCCGCTCGCCCATGGCG
CCGTGCGGCGTGGGGCGGGCAATGGCGCGGATGGCGGCGGGAGCGCCGGCGAGGCGCATTTCATTGGCCTGCCCGGCAAC
CCGGTATCGAGCTTCGTCACCTTCCTGCTGTTCGTGCGGCCGTTCCTGCTGCGGCTCGCGGGCGCCGCCCAGGTCGCGCC
GCGCGCGCTGTCGCTGCGCGCCGATTTCACGCTCGCCAAGGGGGACCGGCGCAACGAGTTCCTGCGCGCGCGCGTCAACG
AGGCGGGTGGCCTCGACCTCTACCCGAACCAGAGCTCGGCGGTGTTGACCTCGACCGTCTGGGGCGACGGCCTGATCGAC
AACCCGCCCAATCACGCGATCAGCGCCGGCGAGACGGTGCGGTTCCTTCCCTTTTCCGACCTGCTCGGCTGA

Upstream 100 bases:

>100_bases
TCATGCCCTCATCAAGCTCGTGCTCGGCAGCCGATCGCCCGCGTCCGCGGCGCGCTCGTTACAATAACGGTTTCGCCGCT
CTGCCCACGCTTCCACCGCG

Downstream 100 bases:

>100_bases
GGCCGGGCACGCAACATCGATGAAGATCGAACTGAAATTCTTTGCGAGCGTGCGCGAGGCGCTCGGCGTGGCAAGCGAAT
CCGTGACGGTGCCGGACGGC

Product: molybdopterin biosynthesis moeA protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSTPASQAPRAPLLSTAEALAALLGAAAPLAQTETVPTLDALGRVLAVDVVSPLDVPPMAISAMDGYAVRVADLTQGTRR
LPVSQRIPAGHAAAPLAAGTAARIFTGAPLPPGADAVVMQEQAEAAGEAVDILHTPKAGEWITAQGADIRRGTVILPAGT
RLAPQALGLAASVGCAHLTVRRRVKVAVFFTGDELTMPGEPLAPGAIYNSNRFTLRGLLERFGCEVSDFGIVPDSLDATR
ATLREAARDHDLIVTSGGVSVGEEDHVKPAVEAEGRLTLWQIAMKPGKPLAHGAVRRGAGNGADGGGSAGEAHFIGLPGN
PVSSFVTFLLFVRPFLLRLAGAAQVAPRALSLRADFTLAKGDRRNEFLRARVNEAGGLDLYPNQSSAVLTSTVWGDGLID
NPPNHAISAGETVRFLPFSDLLG

Sequences:

>Translated_423_residues
MSTPASQAPRAPLLSTAEALAALLGAAAPLAQTETVPTLDALGRVLAVDVVSPLDVPPMAISAMDGYAVRVADLTQGTRR
LPVSQRIPAGHAAAPLAAGTAARIFTGAPLPPGADAVVMQEQAEAAGEAVDILHTPKAGEWITAQGADIRRGTVILPAGT
RLAPQALGLAASVGCAHLTVRRRVKVAVFFTGDELTMPGEPLAPGAIYNSNRFTLRGLLERFGCEVSDFGIVPDSLDATR
ATLREAARDHDLIVTSGGVSVGEEDHVKPAVEAEGRLTLWQIAMKPGKPLAHGAVRRGAGNGADGGGSAGEAHFIGLPGN
PVSSFVTFLLFVRPFLLRLAGAAQVAPRALSLRADFTLAKGDRRNEFLRARVNEAGGLDLYPNQSSAVLTSTVWGDGLID
NPPNHAISAGETVRFLPFSDLLG
>Mature_422_residues
STPASQAPRAPLLSTAEALAALLGAAAPLAQTETVPTLDALGRVLAVDVVSPLDVPPMAISAMDGYAVRVADLTQGTRRL
PVSQRIPAGHAAAPLAAGTAARIFTGAPLPPGADAVVMQEQAEAAGEAVDILHTPKAGEWITAQGADIRRGTVILPAGTR
LAPQALGLAASVGCAHLTVRRRVKVAVFFTGDELTMPGEPLAPGAIYNSNRFTLRGLLERFGCEVSDFGIVPDSLDATRA
TLREAARDHDLIVTSGGVSVGEEDHVKPAVEAEGRLTLWQIAMKPGKPLAHGAVRRGAGNGADGGGSAGEAHFIGLPGNP
VSSFVTFLLFVRPFLLRLAGAAQVAPRALSLRADFTLAKGDRRNEFLRARVNEAGGLDLYPNQSSAVLTSTVWGDGLIDN
PPNHAISAGETVRFLPFSDLLG

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=409, Percent_Identity=34.4743276283619, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI66932975, Length=409, Percent_Identity=34.4743276283619, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI1787049, Length=395, Percent_Identity=42.5316455696203, Blast_Score=274, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI25147659, Length=386, Percent_Identity=31.8652849740933, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17562606, Length=415, Percent_Identity=25.7831325301205, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17136978, Length=413, Percent_Identity=35.1089588377724, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24638841, Length=413, Percent_Identity=35.1089588377724, Blast_Score=169, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 43763; Mature: 43632

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPASQAPRAPLLSTAEALAALLGAAAPLAQTETVPTLDALGRVLAVDVVSPLDVPPMA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCE
ISAMDGYAVRVADLTQGTRRLPVSQRIPAGHAAAPLAAGTAARIFTGAPLPPGADAVVMQ
EEECCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCHHCCCHHHEEECCCCCCCCCEEEEH
EQAEAAGEAVDILHTPKAGEWITAQGADIRRGTVILPAGTRLAPQALGLAASVGCAHLTV
HHHHHCCCEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHEE
RRRVKVAVFFTGDELTMPGEPLAPGAIYNSNRFTLRGLLERFGCEVSDFGIVPDSLDATR
EEEEEEEEEEECCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHH
ATLREAARDHDLIVTSGGVSVGEEDHVKPAVEAEGRLTLWQIAMKPGKPLAHGAVRRGAG
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHCCCC
NGADGGGSAGEAHFIGLPGNPVSSFVTFLLFVRPFLLRLAGAAQVAPRALSLRADFTLAK
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEECEEEEC
GDRRNEFLRARVNEAGGLDLYPNQSSAVLTSTVWGDGLIDNPPNHAISAGETVRFLPFSD
CCCHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHH
LLG
HCC
>Mature Secondary Structure 
STPASQAPRAPLLSTAEALAALLGAAAPLAQTETVPTLDALGRVLAVDVVSPLDVPPMA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCE
ISAMDGYAVRVADLTQGTRRLPVSQRIPAGHAAAPLAAGTAARIFTGAPLPPGADAVVMQ
EEECCCCEEEEEECCCCCCCCCCHHCCCCCCCCCCHHCCCHHHEEECCCCCCCCCEEEEH
EQAEAAGEAVDILHTPKAGEWITAQGADIRRGTVILPAGTRLAPQALGLAASVGCAHLTV
HHHHHCCCEEEEEECCCCCCEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCHHHHEE
RRRVKVAVFFTGDELTMPGEPLAPGAIYNSNRFTLRGLLERFGCEVSDFGIVPDSLDATR
EEEEEEEEEEECCEEECCCCCCCCCEEECCCCHHHHHHHHHHCCCEECCCCCCCCCHHHH
ATLREAARDHDLIVTSGGVSVGEEDHVKPAVEAEGRLTLWQIAMKPGKPLAHGAVRRGAG
HHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHCCCC
NGADGGGSAGEAHFIGLPGNPVSSFVTFLLFVRPFLLRLAGAAQVAPRALSLRADFTLAK
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEEECEEEEC
GDRRNEFLRARVNEAGGLDLYPNQSSAVLTSTVWGDGLIDNPPNHAISAGETVRFLPFSD
CCCHHHHHHHHHCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECCHH
LLG
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]