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The map label for this gene is glcR [H]

Identifier: 238026748

GI number: 238026748

Start: 1214961

End: 1215728

Strand: Reverse

Name: glcR [H]

Synonym: bglu_1g11060

Alternate gene names: 238026748

Gene position: 1215728-1214961 (Counterclockwise)

Preceding gene: 238026749

Following gene: 238026747

Centisome position: 31.12

GC content: 76.56

Gene sequence:

>768_bases
ATGTGGCAGGAAGACCGTCATCAACGCATCCGCGCACTGCTCGGCGCGCTGCAGCGCGTGTCGATCGAGCGGATCATGGC
GGAACTCGGCGTCTCGCGCGAAACCGTGCGACGCGATCTGCTCGACCTGGAGGCGCTCGGCGCGCTGGTACGCGTGCGCG
GCGGCGCGCTGCTTCCCGATGCGACGCTGCCGGCCGCTCGCGCGCCGGCGCGCGAGCGCATCGAGCGCGCGATCGCGAAG
GCCGCGGCCGGCCAGGTCGGCACCGGCCAGACGCTGTTCATCGACGCCGCCCCGCTCACCCGCGCGCTCGCCGACCAACT
CGCGACGCTCACCGGCCTGACCGTCGTCACCAACTCGCTCGAGGTGGCGGCGCGGCTGTGCACGCCGGGCGGCCGCGCGG
GCCCGCCCAACCAGGTGGTGGTGCTGGGCGGCACGCTGGGCGCGCGCACGCTCGCCACGGCCGACGCGCAGACCGTGCGC
GAAGTCCGGCGCCATCGCGCCGATCTGGCGCTGCTGGCGCCGGACGGGCTCGACGCGCAGCACGGCGCAAGCCACGCCGA
CCGCGCCGAAGCCGAGGTCGCGCGCGCGATGTGCGAGGCCGCCGAGCGCGTCGTGATGCTGGCCGACGCCGGCCGCCTCG
GCCGGCGCAGCCGCATCGCCTACTGCCCGAGCGAGGCGATCGACCTGCTCGTCACGCCGCGCGACGCACGCGGCGCGGCC
GGCTTCGCCGCGCTCGCCGAGCGCGTGCCCAGGGTCGTGCTGGCCTGA

Upstream 100 bases:

>100_bases
TGCCCCGCAACTGCCACGCAAGCCTGCAACACTGGCGCCTCGCCGCGGGCGCGAATCCCCCTGCGGCCAGACGCAGGCGC
CTTCGACAGGACGACATCTC

Downstream 100 bases:

>100_bases
GCGCCGCCGCCGGCCGCTGCCGCCAGGGCCGTCGAGGCCTCATGCAGCGGCCCGTTGCACGGCGCGCGCGCCGCGCTGCC
CGGCTCACGGGCTTGCAGAG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MWQEDRHQRIRALLGALQRVSIERIMAELGVSRETVRRDLLDLEALGALVRVRGGALLPDATLPAARAPARERIERAIAK
AAAGQVGTGQTLFIDAAPLTRALADQLATLTGLTVVTNSLEVAARLCTPGGRAGPPNQVVVLGGTLGARTLATADAQTVR
EVRRHRADLALLAPDGLDAQHGASHADRAEAEVARAMCEAAERVVMLADAGRLGRRSRIAYCPSEAIDLLVTPRDARGAA
GFAALAERVPRVVLA

Sequences:

>Translated_255_residues
MWQEDRHQRIRALLGALQRVSIERIMAELGVSRETVRRDLLDLEALGALVRVRGGALLPDATLPAARAPARERIERAIAK
AAAGQVGTGQTLFIDAAPLTRALADQLATLTGLTVVTNSLEVAARLCTPGGRAGPPNQVVVLGGTLGARTLATADAQTVR
EVRRHRADLALLAPDGLDAQHGASHADRAEAEVARAMCEAAERVVMLADAGRLGRRSRIAYCPSEAIDLLVTPRDARGAA
GFAALAERVPRVVLA
>Mature_255_residues
MWQEDRHQRIRALLGALQRVSIERIMAELGVSRETVRRDLLDLEALGALVRVRGGALLPDATLPAARAPARERIERAIAK
AAAGQVGTGQTLFIDAAPLTRALADQLATLTGLTVVTNSLEVAARLCTPGGRAGPPNQVVVLGGTLGARTLATADAQTVR
EVRRHRADLALLAPDGLDAQHGASHADRAEAEVARAMCEAAERVVMLADAGRLGRRSRIAYCPSEAIDLLVTPRDARGAA
GFAALAERVPRVVLA

Specific function: Plays a role in carbon catabolite repression (CCR). Specifically required for transcriptional repression of the levanase operon by glucose but not by other sugars [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=29.2372881355932, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=29.2372881355932, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789519, Length=218, Percent_Identity=27.9816513761468, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789059, Length=232, Percent_Identity=27.1551724137931, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=26.3374485596708, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787540, Length=238, Percent_Identity=25.6302521008403, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082344, Length=211, Percent_Identity=27.4881516587678, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=27.4261603375527, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26908; Mature: 26908

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQEDRHQRIRALLGALQRVSIERIMAELGVSRETVRRDLLDLEALGALVRVRGGALLPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ATLPAARAPARERIERAIAKAAAGQVGTGQTLFIDAAPLTRALADQLATLTGLTVVTNSL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
EVAARLCTPGGRAGPPNQVVVLGGTLGARTLATADAQTVREVRRHRADLALLAPDGLDAQ
HHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
HGASHADRAEAEVARAMCEAAERVVMLADAGRLGRRSRIAYCPSEAIDLLVTPRDARGAA
CCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEECCHHHHEEEECCCCCCCHH
GFAALAERVPRVVLA
HHHHHHHHCCHHHCC
>Mature Secondary Structure
MWQEDRHQRIRALLGALQRVSIERIMAELGVSRETVRRDLLDLEALGALVRVRGGALLPD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ATLPAARAPARERIERAIAKAAAGQVGTGQTLFIDAAPLTRALADQLATLTGLTVVTNSL
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
EVAARLCTPGGRAGPPNQVVVLGGTLGARTLATADAQTVREVRRHRADLALLAPDGLDAQ
HHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
HGASHADRAEAEVARAMCEAAERVVMLADAGRLGRRSRIAYCPSEAIDLLVTPRDARGAA
CCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEECCHHHHEEEECCCCCCCHH
GFAALAERVPRVVLA
HHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]