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The map label for this gene is atoC [H]

Identifier: 238026623

GI number: 238026623

Start: 1045102

End: 1046502

Strand: Reverse

Name: atoC [H]

Synonym: bglu_1g09700

Alternate gene names: 238026623

Gene position: 1046502-1045102 (Counterclockwise)

Preceding gene: 238026624

Following gene: 238026600

Centisome position: 26.79

GC content: 69.52

Gene sequence:

>1401_bases
ATGCCCCACGCCCTCATAGTCGAAGACGATCCCAACAGCTTGTCCGGCCTGACGGCGCTGCTCGCCGCGGACGGATTCAC
GGTCGACACGGCCACCTCGCTCGCCGAGGCCCGGGCGGCACTGGCGCGGACGATTCCCGACGTCGTGCTGGTCGACCTGA
ACCTGCCGGACGGCAGCGGCTTCGACCTGTTGCAGCATTTGCCCCAGCCGCAGCAGCCGAACGGCGGCCTGCCCGTGATC
GTGCTGACCGGCAACGCCACGGTCGAGAGCGCCATCGAGGGCTTGCGCTACGGCATTTGGGACTACCTGCTGAAGCCCGT
CAACATCCCGCGCTTGCGCAGTCTGCTGGCGCGCATTCCGCGCCCTTACGAGCTGATCGAGGAAGTCCAGGCACTGCGCA
CCACGCTGCGCAAACTCGGCCGTTTCGGCCCCCTGATCGGGCGCAGCAACGCAGTCCAGCATGTCTACGACATGATCGAG
CGCAACGCGCGCAGCGAGGCTGCGGTGCTGGTGTGGGGCGAAGCCGGCACCGGAAAGGAGACGACGGCTCGGGCGCTGCA
TGACCTGAGCCGCCGCCGCAAGGGACCGTTCATCAAGTTCGACTGCCGTGCCGCGCTGCAGCTGCCGCGCGTGATGGAAC
TCGGCAACATCGTCATCGAAAGCATGCTGTTCGGCCGCGAGCGCGGCTCCTACGGCGGCGCCGAGCGGCGCGAGCCGGGC
CTCTTCGAGCAGGCGAGCGGCGGCACGCTGCTGCTCAAGGACATCACGGCGCTGCCGCTGCCGATCCAGGAATCGCTGCT
GCGCGCGCTCGACTCGCAAAGCTTCCGGCGCATCGAGGGCACCACCGAAGTGGCCACCGACTTCCGGCTGATCGCCACCT
CGCGCCGGCCGTCGCGCGAGGCGCTCGACCACGGCACGCTGCGCGAGGATCTGTGGATGCGGCTCGACGCGGCCTCGATC
GCGCTGCCGCCGCTGCGCGCGCGCGACGACGACATGCTGCAGATCGCCCAGGCCTTCGTCGACGATCTGAACCGCCAGGC
GCACGACGCCGGCCTCGGCGCCGTCGCCAAGCGGATCGCGCCCGACTTCATTCGCGAATGCCTCGCCTACGACTGGCCAG
GCAACGTGCGCGAACTGCGCGATCGCGTGCGGCTCGCCTACGAGGCGTCGGGCGATTTCATCGAGTCGCTGCGCGCCAAC
GACGGCGTGTTCGTGCCGGGCGCGGCGCTCAGCGGCAGCAGCGTCCAGGTGCGCGTCGGCACGCCGCTGTCGGACGTGGA
AGACCTGTTGATCCGCGCCACGCTCGACGCGGTCGGCGGCACCCGCCATCGCGCGGCCGCGCTGCTCGGCATCAGCCCGA
AGACGCTCTACAACAAGCTGCAGCGCATGAAGATGAACTGA

Upstream 100 bases:

>100_bases
GTACGCTTTATGCCCCGGGGGACATAAAATCCGACTCTAATCAAACAATGGGGCCAACGCGCCCGCCACGCACGGTCGCC
CTTTGAACATCCAGCACACC

Downstream 100 bases:

>100_bases
CGGCGGCACTCGCCGCCGGCCGCCGCCCCGCCGATCTCAGCCGAACGTCTCGCGCAGCAGCGCGCAGGCACGCTGGTACT
CGGGCCGGCGCATCAGCTTG

Product: Sigma-54 dependent DNA-binding response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPHALIVEDDPNSLSGLTALLAADGFTVDTATSLAEARAALARTIPDVVLVDLNLPDGSGFDLLQHLPQPQQPNGGLPVI
VLTGNATVESAIEGLRYGIWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRTTLRKLGRFGPLIGRSNAVQHVYDMIE
RNARSEAAVLVWGEAGTGKETTARALHDLSRRRKGPFIKFDCRAALQLPRVMELGNIVIESMLFGRERGSYGGAERREPG
LFEQASGGTLLLKDITALPLPIQESLLRALDSQSFRRIEGTTEVATDFRLIATSRRPSREALDHGTLREDLWMRLDAASI
ALPPLRARDDDMLQIAQAFVDDLNRQAHDAGLGAVAKRIAPDFIRECLAYDWPGNVRELRDRVRLAYEASGDFIESLRAN
DGVFVPGAALSGSSVQVRVGTPLSDVEDLLIRATLDAVGGTRHRAAALLGISPKTLYNKLQRMKMN

Sequences:

>Translated_466_residues
MPHALIVEDDPNSLSGLTALLAADGFTVDTATSLAEARAALARTIPDVVLVDLNLPDGSGFDLLQHLPQPQQPNGGLPVI
VLTGNATVESAIEGLRYGIWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRTTLRKLGRFGPLIGRSNAVQHVYDMIE
RNARSEAAVLVWGEAGTGKETTARALHDLSRRRKGPFIKFDCRAALQLPRVMELGNIVIESMLFGRERGSYGGAERREPG
LFEQASGGTLLLKDITALPLPIQESLLRALDSQSFRRIEGTTEVATDFRLIATSRRPSREALDHGTLREDLWMRLDAASI
ALPPLRARDDDMLQIAQAFVDDLNRQAHDAGLGAVAKRIAPDFIRECLAYDWPGNVRELRDRVRLAYEASGDFIESLRAN
DGVFVPGAALSGSSVQVRVGTPLSDVEDLLIRATLDAVGGTRHRAAALLGISPKTLYNKLQRMKMN
>Mature_465_residues
PHALIVEDDPNSLSGLTALLAADGFTVDTATSLAEARAALARTIPDVVLVDLNLPDGSGFDLLQHLPQPQQPNGGLPVIV
LTGNATVESAIEGLRYGIWDYLLKPVNIPRLRSLLARIPRPYELIEEVQALRTTLRKLGRFGPLIGRSNAVQHVYDMIER
NARSEAAVLVWGEAGTGKETTARALHDLSRRRKGPFIKFDCRAALQLPRVMELGNIVIESMLFGRERGSYGGAERREPGL
FEQASGGTLLLKDITALPLPIQESLLRALDSQSFRRIEGTTEVATDFRLIATSRRPSREALDHGTLREDLWMRLDAASIA
LPPLRARDDDMLQIAQAFVDDLNRQAHDAGLGAVAKRIAPDFIRECLAYDWPGNVRELRDRVRLAYEASGDFIESLRAND
GVFVPGAALSGSSVQVRVGTPLSDVEDLLIRATLDAVGGTRHRAAALLGISPKTLYNKLQRMKMN

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=462, Percent_Identity=34.6320346320346, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1790437, Length=468, Percent_Identity=33.3333333333333, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1790299, Length=485, Percent_Identity=34.020618556701, Blast_Score=218, Evalue=9e-58,
Organism=Escherichia coli, GI1788905, Length=379, Percent_Identity=32.9815303430079, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1789233, Length=333, Percent_Identity=32.7327327327327, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI87082117, Length=352, Percent_Identity=33.2386363636364, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI1789087, Length=343, Percent_Identity=33.5276967930029, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1786524, Length=346, Percent_Identity=32.9479768786127, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87081872, Length=240, Percent_Identity=35.8333333333333, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI87082152, Length=267, Percent_Identity=32.9588014981273, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787583, Length=267, Percent_Identity=31.4606741573034, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1789828, Length=273, Percent_Identity=30.4029304029304, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081858, Length=301, Percent_Identity=25.2491694352159, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786838, Length=133, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=34.7457627118644, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790552, Length=118, Percent_Identity=37.2881355932203, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51076; Mature: 50945

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHALIVEDDPNSLSGLTALLAADGFTVDTATSLAEARAALARTIPDVVLVDLNLPDGSG
CCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
FDLLQHLPQPQQPNGGLPVIVLTGNATVESAIEGLRYGIWDYLLKPVNIPRLRSLLARIP
HHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RPYELIEEVQALRTTLRKLGRFGPLIGRSNAVQHVYDMIERNARSEAAVLVWGEAGTGKE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
TTARALHDLSRRRKGPFIKFDCRAALQLPRVMELGNIVIESMLFGRERGSYGGAERREPG
HHHHHHHHHHHHHCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LFEQASGGTLLLKDITALPLPIQESLLRALDSQSFRRIEGTTEVATDFRLIATSRRPSRE
CCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCHH
ALDHGTLREDLWMRLDAASIALPPLRARDDDMLQIAQAFVDDLNRQAHDAGLGAVAKRIA
HHHCCCHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDFIRECLAYDWPGNVRELRDRVRLAYEASGDFIESLRANDGVFVPGAALSGSSVQVRVG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCCCCEEEEEEC
TPLSDVEDLLIRATLDAVGGTRHRAAALLGISPKTLYNKLQRMKMN
CCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHALIVEDDPNSLSGLTALLAADGFTVDTATSLAEARAALARTIPDVVLVDLNLPDGSG
CCEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
FDLLQHLPQPQQPNGGLPVIVLTGNATVESAIEGLRYGIWDYLLKPVNIPRLRSLLARIP
HHHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
RPYELIEEVQALRTTLRKLGRFGPLIGRSNAVQHVYDMIERNARSEAAVLVWGEAGTGKE
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
TTARALHDLSRRRKGPFIKFDCRAALQLPRVMELGNIVIESMLFGRERGSYGGAERREPG
HHHHHHHHHHHHHCCCEEEEECHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LFEQASGGTLLLKDITALPLPIQESLLRALDSQSFRRIEGTTEVATDFRLIATSRRPSRE
CCCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCHH
ALDHGTLREDLWMRLDAASIALPPLRARDDDMLQIAQAFVDDLNRQAHDAGLGAVAKRIA
HHHCCCHHHHHHHHHCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDFIRECLAYDWPGNVRELRDRVRLAYEASGDFIESLRANDGVFVPGAALSGSSVQVRVG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCEECCCCCCCCCEEEEEEC
TPLSDVEDLLIRATLDAVGGTRHRAAALLGISPKTLYNKLQRMKMN
CCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]