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The map label for this gene is nuoF2 [H]

Identifier: 238026515

GI number: 238026515

Start: 933495

End: 935069

Strand: Reverse

Name: nuoF2 [H]

Synonym: bglu_1g08590

Alternate gene names: 238026515

Gene position: 935069-933495 (Counterclockwise)

Preceding gene: 238026516

Following gene: 238026514

Centisome position: 23.94

GC content: 70.86

Gene sequence:

>1575_bases
ATGAGCCAGTCCGCCGTCCGCATCCATGTGCCACGCGACTCGGCCGCGCTGGCGGTCGGCGCCGAGGCGCTGGCCCGCGC
GATCACGGCCGAAGCCGCCGCGCGCGGCGTGCCCATCGACCTCGTGCGCAATGGCTCGCGCGGCCTGCTGTGGCTCGAGC
CGCTCGTCGAGATCACCACGCCGGCCGGCCGCATCGGTTACGCGAACCTGTCGGCTGACGACGTCGGCGCGCTGTTCGAC
GCAGGCTGGCTCGAGGGCGGCGAGCACCCGTCGCGCGTCGGCCTCGTCGACGAGCTGCCCTGGCTCAAGCGCCAGCAGCG
CCTGACCTTTGCGCGGATCGGCATCACCGACCCGCTGTCGATCGACGACTATCTCGCGCACGGCGGCCTCGACGGCCTGA
AGCGCGCGCTCACGCTCGACGGCGCCGCAGCCTGCGAGGAACTGATCGAATCGGGCCTGCGCGGGCGCGGCGGCGCCGCG
TTCCCGGCCGGCATCAAATGGCGTACGGTGCGCCAGGCGCAAGCCACGCAGAAATACGTGGTCTGCAATGCCGACGAGGG
GGATTCGGGCACGTTCTCGGATCGCCTGATCATGGAAAGCGATCCGTATTGCCTGATCGAAGGGATGATCATCGCCGGCG
TGGTGACCGGCGCAACGCGCGGCCATATCTATGTGCGCAGCGAGTACCCGCATGCGATCGCGGCCCTGAACGAGGCGATC
GCGCGGGCGCGCGCGGCCGGCTGGCTCGGCGAGAGCGTGCTCGGCTCGGGGCTCGGGTTCGAACTCGAAGTGGCGAAAGG
CGCCGGCGCCTACGTGTGCGGCGAGGAAACCGCGCTGCTCGAATCGCTCGAGGGCAAGCGCGGCGTGGTGCGCGCCAAGC
CGCCGCTGCCGGCCCTCGAAGGCCTGCACGGCCAGCCGACCGTGATCAACAACGTGATTACGCTGGCCACCGCGCCGATC
ATCTTCGCGCGCGGCGCCGCGTTCTATCGCGACTACGGCATGGGTCGCTCGCGCGGCACGCTGCCGTTCCAGCTGGCCGG
CAACATCCGCCAGGGCGGCCTCGTCGAGCTCGCGTTCGGCGTGACGCTGCGCGAGCTGCTGTTCGAGTTCGGCGGCGGCA
CGGCCAGCGGCCGCCCGGCACGCGCCGCGCAGGTGGGCGGCCCGCTCGGCACCTACCTGCCCGAGAGCCAGTGGGACATC
CCGCTCGACTATGAAGCCTATGCGGCCGTCGGCGCGGTGGTCGGGCACGGCGGCATCGTGCTGCACGACGACACCTCGAA
CCTGGCCGAGCTGGCCGAGTATGCGATGCAGTTCTGTGTCCTCGAATCGTGCGGCAAATGCACGCCATGCCGGATCGGCT
CGACGCGCGGCGTCGAGACCATCGCGCGAATCCGCGGCGGCGACACGTCCGAGAAGCAGGTCCACCTGCTGCGCGACCTC
TGCGACACGATGATGGCCGGCTCGCTCTGCGCGATGGGCGGGATGACGCCGTACCCGGTGCTGTCCGCGCTCGATCATTT
TCCGGAAGATTTCGGCCTCGCCGGTGCCCCCGTGGCGTCGAAAGCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TGATCAACGGCGAGCCGCATGCGCGCCTGAGCCCGGCGCGCTTCGACGCGCTGCTCGCCGCAGCCGTGGCCGACACCGCC
GCCGACCTGAAGGAGCCCGT

Downstream 100 bases:

>100_bases
CAGGAGACCACGATGTCCACCCAAGCATTCGACAGCAGCGCGCCAGCCGGGGGCTGCGGCTCCGGCAATTGTGCCTGCAA
GAGCGCCGCGCAGGCGCGCC

Product: formate dehydrogenase subunit beta

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 524; Mature: 523

Protein sequence:

>524_residues
MSQSAVRIHVPRDSAALAVGAEALARAITAEAAARGVPIDLVRNGSRGLLWLEPLVEITTPAGRIGYANLSADDVGALFD
AGWLEGGEHPSRVGLVDELPWLKRQQRLTFARIGITDPLSIDDYLAHGGLDGLKRALTLDGAAACEELIESGLRGRGGAA
FPAGIKWRTVRQAQATQKYVVCNADEGDSGTFSDRLIMESDPYCLIEGMIIAGVVTGATRGHIYVRSEYPHAIAALNEAI
ARARAAGWLGESVLGSGLGFELEVAKGAGAYVCGEETALLESLEGKRGVVRAKPPLPALEGLHGQPTVINNVITLATAPI
IFARGAAFYRDYGMGRSRGTLPFQLAGNIRQGGLVELAFGVTLRELLFEFGGGTASGRPARAAQVGGPLGTYLPESQWDI
PLDYEAYAAVGAVVGHGGIVLHDDTSNLAELAEYAMQFCVLESCGKCTPCRIGSTRGVETIARIRGGDTSEKQVHLLRDL
CDTMMAGSLCAMGGMTPYPVLSALDHFPEDFGLAGAPVASKAAA

Sequences:

>Translated_524_residues
MSQSAVRIHVPRDSAALAVGAEALARAITAEAAARGVPIDLVRNGSRGLLWLEPLVEITTPAGRIGYANLSADDVGALFD
AGWLEGGEHPSRVGLVDELPWLKRQQRLTFARIGITDPLSIDDYLAHGGLDGLKRALTLDGAAACEELIESGLRGRGGAA
FPAGIKWRTVRQAQATQKYVVCNADEGDSGTFSDRLIMESDPYCLIEGMIIAGVVTGATRGHIYVRSEYPHAIAALNEAI
ARARAAGWLGESVLGSGLGFELEVAKGAGAYVCGEETALLESLEGKRGVVRAKPPLPALEGLHGQPTVINNVITLATAPI
IFARGAAFYRDYGMGRSRGTLPFQLAGNIRQGGLVELAFGVTLRELLFEFGGGTASGRPARAAQVGGPLGTYLPESQWDI
PLDYEAYAAVGAVVGHGGIVLHDDTSNLAELAEYAMQFCVLESCGKCTPCRIGSTRGVETIARIRGGDTSEKQVHLLRDL
CDTMMAGSLCAMGGMTPYPVLSALDHFPEDFGLAGAPVASKAAA
>Mature_523_residues
SQSAVRIHVPRDSAALAVGAEALARAITAEAAARGVPIDLVRNGSRGLLWLEPLVEITTPAGRIGYANLSADDVGALFDA
GWLEGGEHPSRVGLVDELPWLKRQQRLTFARIGITDPLSIDDYLAHGGLDGLKRALTLDGAAACEELIESGLRGRGGAAF
PAGIKWRTVRQAQATQKYVVCNADEGDSGTFSDRLIMESDPYCLIEGMIIAGVVTGATRGHIYVRSEYPHAIAALNEAIA
RARAAGWLGESVLGSGLGFELEVAKGAGAYVCGEETALLESLEGKRGVVRAKPPLPALEGLHGQPTVINNVITLATAPII
FARGAAFYRDYGMGRSRGTLPFQLAGNIRQGGLVELAFGVTLRELLFEFGGGTASGRPARAAQVGGPLGTYLPESQWDIP
LDYEAYAAVGAVVGHGGIVLHDDTSNLAELAEYAMQFCVLESCGKCTPCRIGSTRGVETIARIRGGDTSEKQVHLLRDLC
DTMMAGSLCAMGGMTPYPVLSALDHFPEDFGLAGAPVASKAAA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI260656005, Length=367, Percent_Identity=37.3297002724796, Blast_Score=246, Evalue=3e-65,
Organism=Homo sapiens, GI20149568, Length=367, Percent_Identity=37.3297002724796, Blast_Score=246, Evalue=3e-65,
Organism=Escherichia coli, GI1788620, Length=407, Percent_Identity=38.0835380835381, Blast_Score=289, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI17531727, Length=420, Percent_Identity=36.1904761904762, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI19920794, Length=380, Percent_Identity=37.1052631578947, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI45550452, Length=368, Percent_Identity=38.3152173913043, Blast_Score=235, Evalue=7e-62,
Organism=Drosophila melanogaster, GI24653819, Length=352, Percent_Identity=31.8181818181818, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653817, Length=332, Percent_Identity=29.8192771084337, Blast_Score=162, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 54992; Mature: 54861

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00644 COMPLEX1_51K_1 ; PS00645 COMPLEX1_51K_2 ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSAVRIHVPRDSAALAVGAEALARAITAEAAARGVPIDLVRNGSRGLLWLEPLVEITT
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECHHHHHCC
PAGRIGYANLSADDVGALFDAGWLEGGEHPSRVGLVDELPWLKRQQRLTFARIGITDPLS
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHCCEEEEECCCCCCC
IDDYLAHGGLDGLKRALTLDGAAACEELIESGLRGRGGAAFPAGIKWRTVRQAQATQKYV
HHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHCCCEEE
VCNADEGDSGTFSDRLIMESDPYCLIEGMIIAGVVTGATRGHIYVRSEYPHAIAALNEAI
EEECCCCCCCCCCCEEEECCCCEEEEHHHHEEHHHCCCCCCEEEEECCCCHHHHHHHHHH
ARARAAGWLGESVLGSGLGFELEVAKGAGAYVCGEETALLESLEGKRGVVRAKPPLPALE
HHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHCCCCCCEEECCCCCHHHC
GLHGQPTVINNVITLATAPIIFARGAAFYRDYGMGRSRGTLPFQLAGNIRQGGLVELAFG
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEEHH
VTLRELLFEFGGGTASGRPARAAQVGGPLGTYLPESQWDIPLDYEAYAAVGAVVGHGGIV
HHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEE
LHDDTSNLAELAEYAMQFCVLESCGKCTPCRIGSTRGVETIARIRGGDTSEKQVHLLRDL
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
CDTMMAGSLCAMGGMTPYPVLSALDHFPEDFGLAGAPVASKAAA
HHHHHHCCHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCHHCCCC
>Mature Secondary Structure 
SQSAVRIHVPRDSAALAVGAEALARAITAEAAARGVPIDLVRNGSRGLLWLEPLVEITT
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECHHHHHCC
PAGRIGYANLSADDVGALFDAGWLEGGEHPSRVGLVDELPWLKRQQRLTFARIGITDPLS
CCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCHHHHHHCCEEEEECCCCCCC
IDDYLAHGGLDGLKRALTLDGAAACEELIESGLRGRGGAAFPAGIKWRTVRQAQATQKYV
HHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHCCCEEE
VCNADEGDSGTFSDRLIMESDPYCLIEGMIIAGVVTGATRGHIYVRSEYPHAIAALNEAI
EEECCCCCCCCCCCEEEECCCCEEEEHHHHEEHHHCCCCCCEEEEECCCCHHHHHHHHHH
ARARAAGWLGESVLGSGLGFELEVAKGAGAYVCGEETALLESLEGKRGVVRAKPPLPALE
HHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECCHHHHHHHCCCCCCEEECCCCCHHHC
GLHGQPTVINNVITLATAPIIFARGAAFYRDYGMGRSRGTLPFQLAGNIRQGGLVELAFG
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEEHH
VTLRELLFEFGGGTASGRPARAAQVGGPLGTYLPESQWDIPLDYEAYAAVGAVVGHGGIV
HHHHHHHHHHCCCCCCCCCCCHHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEE
LHDDTSNLAELAEYAMQFCVLESCGKCTPCRIGSTRGVETIARIRGGDTSEKQVHLLRDL
EECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
CDTMMAGSLCAMGGMTPYPVLSALDHFPEDFGLAGAPVASKAAA
HHHHHHCCHHHHCCCCHHHHHHHHHHCCHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]