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The map label for this gene is purP [H]

Identifier: 238026503

GI number: 238026503

Start: 915760

End: 917136

Strand: Reverse

Name: purP [H]

Synonym: bglu_1g08470

Alternate gene names: 238026503

Gene position: 917136-915760 (Counterclockwise)

Preceding gene: 238026504

Following gene: 238026502

Centisome position: 23.48

GC content: 67.76

Gene sequence:

>1377_bases
ATGGACACGTACAACGGCAGCAAGGCCCCGGCCACGAGTTCGTGGCTCGACCGATTCTTCGGCATCCGCGAGTCCGGCTC
GCGGCTGCGCACGGAAATCGTCGCGGGCGTCACGACGTTCCTGACGGCGATGTACATCATCGTCGTCAATCCCGGCATCC
TGTCTCAGGCAGGCGTGCCGTTCGCGTCGGCGCTGACCGCCACCGTGATCGTCAGCTTCCTCGGCAGTTGCGCGATGGGC
CTGTACGCACGCAATCCGGTGCTGGTCGCGCCGGGCATGGGCATGAACGCGTTGTTCGCGTTCGTGATGGTCCACGGCGG
CAGGATGCCGTGGCAGACCGCGCTCGGCTGCGTGTTCTGGGCCGGCGTGATCTTCGCCGTGCTGGCCGCGTTCAACGCGC
GCAAGCTGGTGGTGGACGCGATCCCGCCCAACCTGCGGCACGCCGTGTCGTGCGGCATCGGCCTCTTCATCTGCCTGATC
GGGCTCGTCAACGCGAAGTTCGTGGTGGGCGATCCGGTGACCGTCGTGCATGCGGCGTCGCTGAACCCGGTGATCGTGAC
GTTCCTCGCCGGGCTCGCGATCACCACCGTGCTGGTGGTGCGCCGCGTGACGGGCGCGCTGATGATCGGCATCGTCGCCA
CCACGCTGCTGGCGGTGCCGATCGGCCGGATCTGGGGCGACGGCAGCGCCTACTGGCCCGCCGCGATCGCCACCCGGACG
CTGGTGAACTGGAACGGCCTGGTGGCGGTGCCCGACTTCTCCGGAATCGGCCAGCTCGACCTGCTCGGCGCGCTCAAGGT
GGCCTACTGGCCGTTCATCTTCGTGATGCTGTTCACCGCCTTCTTCGACGCGCTGTCCACCTTCATGGCGATCTCGGAGG
CCGGCAACCTGGTCGATCGCGACGGCAATCCGCGCAACATTCGCCAGTCGATGATGGTGGACGCGTTCTCGGCGTTGGTC
TCGGCGCCGCTCGGCACGAGCCCCGCGAACGCCTACATCGAGTCGGCCGCCGGCATCTCGGCGGGCGGGCGCACCGGCCT
CGTGGCGGTGGTGGCCGGGCTCTGCTTCCTGCCGTTCCTCGTGCTCTCGCCGCTGCTCTCGCTGGTGCCCGCGATCGCCA
CCGCGCCCGCGCTAATCCTGGTGGGCGTGTTCATGATGGAGTCGATCACGAAGATCGAATGGCACCGCTTCGACGAGGCG
ATCCCCGCCTTCATCGCGATGGTGCTGATCCCGCTCACCTACTCGATCACCGACGGCATCGCCTACGGCTTCCTCGCGTT
CGTGGTGCTGAAGCTGTTCACCGGGCGCCGCCGCGAAATCAAGCCGGCGATGTGGATCGTCGCCGCGCTTTCGGGCGTGC
TGCTCGCGCAGCTTTGA

Upstream 100 bases:

>100_bases
GACGCCCGCGTCCTGCCGAGGAAGCCGGTGCATCCGCTCCGCGCGGCATCGCGCGGACGCACCGTCGTCCCCATAACAGA
GACTGAGGAGAGCTTTCCCG

Downstream 100 bases:

>100_bases
GGCCGCCGGTGCGCCCCGTTCATCTGTCGCAGGAGTTTCGCCCATGACCCAATCCGCGTTTCGCGCCCGGCTGCTGACGT
TTCGCGGCGACCCCGCGCAC

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MDTYNGSKAPATSSWLDRFFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFASALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFAFVMVHGGRMPWQTALGCVFWAGVIFAVLAAFNARKLVVDAIPPNLRHAVSCGIGLFICLI
GLVNAKFVVGDPVTVVHAASLNPVIVTFLAGLAITTVLVVRRVTGALMIGIVATTLLAVPIGRIWGDGSAYWPAAIATRT
LVNWNGLVAVPDFSGIGQLDLLGALKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLVDRDGNPRNIRQSMMVDAFSALV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFLPFLVLSPLLSLVPAIATAPALILVGVFMMESITKIEWHRFDEA
IPAFIAMVLIPLTYSITDGIAYGFLAFVVLKLFTGRRREIKPAMWIVAALSGVLLAQL

Sequences:

>Translated_458_residues
MDTYNGSKAPATSSWLDRFFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFASALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFAFVMVHGGRMPWQTALGCVFWAGVIFAVLAAFNARKLVVDAIPPNLRHAVSCGIGLFICLI
GLVNAKFVVGDPVTVVHAASLNPVIVTFLAGLAITTVLVVRRVTGALMIGIVATTLLAVPIGRIWGDGSAYWPAAIATRT
LVNWNGLVAVPDFSGIGQLDLLGALKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLVDRDGNPRNIRQSMMVDAFSALV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFLPFLVLSPLLSLVPAIATAPALILVGVFMMESITKIEWHRFDEA
IPAFIAMVLIPLTYSITDGIAYGFLAFVVLKLFTGRRREIKPAMWIVAALSGVLLAQL
>Mature_458_residues
MDTYNGSKAPATSSWLDRFFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVPFASALTATVIVSFLGSCAMG
LYARNPVLVAPGMGMNALFAFVMVHGGRMPWQTALGCVFWAGVIFAVLAAFNARKLVVDAIPPNLRHAVSCGIGLFICLI
GLVNAKFVVGDPVTVVHAASLNPVIVTFLAGLAITTVLVVRRVTGALMIGIVATTLLAVPIGRIWGDGSAYWPAAIATRT
LVNWNGLVAVPDFSGIGQLDLLGALKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLVDRDGNPRNIRQSMMVDAFSALV
SAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFLPFLVLSPLLSLVPAIATAPALILVGVFMMESITKIEWHRFDEA
IPAFIAMVLIPLTYSITDGIAYGFLAFVVLKLFTGRRREIKPAMWIVAALSGVLLAQL

Specific function: High-affinity uptake of adenine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=451, Percent_Identity=38.8026607538803, Blast_Score=304, Evalue=7e-84,
Organism=Escherichia coli, GI87082309, Length=453, Percent_Identity=39.0728476821192, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1790499, Length=442, Percent_Identity=37.3303167420815, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI48994909, Length=458, Percent_Identity=34.9344978165939, Blast_Score=238, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48375; Mature: 48375

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTYNGSKAPATSSWLDRFFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
FASALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFAFVMVHGGRMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVIFAVLAAFNARKLVVDAIPPNLRHAVSCGIGLFICLIGLVNAKFVVGDPVTVVHAAS
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECC
LNPVIVTFLAGLAITTVLVVRRVTGALMIGIVATTLLAVPIGRIWGDGSAYWPAAIATRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGLVAVPDFSGIGQLDLLGALKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLVDR
HCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMMVDAFSALVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFLPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VLSPLLSLVPAIATAPALILVGVFMMESITKIEWHRFDEAIPAFIAMVLIPLTYSITDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRREIKPAMWIVAALSGVLLAQL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTYNGSKAPATSSWLDRFFGIRESGSRLRTEIVAGVTTFLTAMYIIVVNPGILSQAGVP
CCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
FASALTATVIVSFLGSCAMGLYARNPVLVAPGMGMNALFAFVMVHGGRMPWQTALGCVFW
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
AGVIFAVLAAFNARKLVVDAIPPNLRHAVSCGIGLFICLIGLVNAKFVVGDPVTVVHAAS
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEECC
LNPVIVTFLAGLAITTVLVVRRVTGALMIGIVATTLLAVPIGRIWGDGSAYWPAAIATRT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LVNWNGLVAVPDFSGIGQLDLLGALKVAYWPFIFVMLFTAFFDALSTFMAISEAGNLVDR
HCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DGNPRNIRQSMMVDAFSALVSAPLGTSPANAYIESAAGISAGGRTGLVAVVAGLCFLPFL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VLSPLLSLVPAIATAPALILVGVFMMESITKIEWHRFDEAIPAFIAMVLIPLTYSITDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGFLAFVVLKLFTGRRREIKPAMWIVAALSGVLLAQL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]