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The map label for this gene is ribE [H]

Identifier: 238026456

GI number: 238026456

Start: 859887

End: 860522

Strand: Reverse

Name: ribE [H]

Synonym: bglu_1g07990

Alternate gene names: 238026456

Gene position: 860522-859887 (Counterclockwise)

Preceding gene: 238026457

Following gene: 238026453

Centisome position: 22.03

GC content: 66.35

Gene sequence:

>636_bases
ATGTTTACCGGAATCGTCGCGGCTGTCGGCCGCATTGAAACCATCGCCCCGCTCGGCAACGGCGCCGATGCCGGCGTGCG
CCTCGTCGTCCACGCCGGCGGCCTCGATCTCGACGACGTCGCGCTCGGCGACAGCATCGCGATCCAGGGCGCCTGCATGA
CGGCGATCGAGAAGACGGCGCAGACCTTCACCGTCGACGTGTCGCGCGAGAGCCTGAACCGCACCGTGGGGCTGACCGAG
CCGGGCGAGGTGAATCTGGAGAAGGCGCTACGCGCGCACGACCGGCTCGGCGGCCATATCGTCTCGGGGCACGTGGACGG
GCTCGGCACGGTCACGCATTTCGCGCCGGTGGGCGAGTCGCACGAACTGCGCGTGCTGGCGCCGAAGGCACTCGGCAAGT
ATCTCGCCCATAAAGGCTCGATCACGGTCAACGGGGTGAGCCTGACGGTGAACGCGGTCGCCGATCGCGAGGACGGCTGC
GAATTCTCGATCAATCTGATTCCGCACACGGTGCAGATGACGACGCTGCGCCATCTGAAGCCGGGAGTGAAAGTCAATCT
CGAGATCGACATGATCGCGCGGTATGTGGAGCGGATGCTCGGGGCGTCTCGGGATGCCGCCAGCCCGTTGCAGTAA

Upstream 100 bases:

>100_bases
AGTACCACTCGATCGACCGGATCGGCGACGACCTGCGCGTGCTCGCGCGGCTGGCCGGCGCGCCGGCCTCCTGATTCTTC
TCGTCCACGGAATTCACACG

Downstream 100 bases:

>100_bases
CCCTCTCCTTGCGACCCGGCCGTCTGCCGCGGCCTCGCGGAATCCGCCCGGCTGACGGACGACGGCAGGCAGACGGAGCG
CGCTCGACGGCCGCGCCTGG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MFTGIVAAVGRIETIAPLGNGADAGVRLVVHAGGLDLDDVALGDSIAIQGACMTAIEKTAQTFTVDVSRESLNRTVGLTE
PGEVNLEKALRAHDRLGGHIVSGHVDGLGTVTHFAPVGESHELRVLAPKALGKYLAHKGSITVNGVSLTVNAVADREDGC
EFSINLIPHTVQMTTLRHLKPGVKVNLEIDMIARYVERMLGASRDAASPLQ

Sequences:

>Translated_211_residues
MFTGIVAAVGRIETIAPLGNGADAGVRLVVHAGGLDLDDVALGDSIAIQGACMTAIEKTAQTFTVDVSRESLNRTVGLTE
PGEVNLEKALRAHDRLGGHIVSGHVDGLGTVTHFAPVGESHELRVLAPKALGKYLAHKGSITVNGVSLTVNAVADREDGC
EFSINLIPHTVQMTTLRHLKPGVKVNLEIDMIARYVERMLGASRDAASPLQ
>Mature_211_residues
MFTGIVAAVGRIETIAPLGNGADAGVRLVVHAGGLDLDDVALGDSIAIQGACMTAIEKTAQTFTVDVSRESLNRTVGLTE
PGEVNLEKALRAHDRLGGHIVSGHVDGLGTVTHFAPVGESHELRVLAPKALGKYLAHKGSITVNGVSLTVNAVADREDGC
EFSINLIPHTVQMTTLRHLKPGVKVNLEIDMIARYVERMLGASRDAASPLQ

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=218, Percent_Identity=34.4036697247706, Blast_Score=95, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319733, Length=208, Percent_Identity=33.1730769230769, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22185; Mature: 22185

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVAAVGRIETIAPLGNGADAGVRLVVHAGGLDLDDVALGDSIAIQGACMTAIEKTA
CCCHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCCHHHEECCCCEEECHHHHHHHHHHH
QTFTVDVSRESLNRTVGLTEPGEVNLEKALRAHDRLGGHIVSGHVDGLGTVTHFAPVGES
HEEEEEECHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHEECCCCC
HELRVLAPKALGKYLAHKGSITVNGVSLTVNAVADREDGCEFSINLIPHTVQMTTLRHLK
CCEEEECHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCEEEEEECCCEEHHHHHHHCC
PGVKVNLEIDMIARYVERMLGASRDAASPLQ
CCCEEEEEHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFTGIVAAVGRIETIAPLGNGADAGVRLVVHAGGLDLDDVALGDSIAIQGACMTAIEKTA
CCCHHHHHHCCCEEECCCCCCCCCCEEEEEEECCCCHHHEECCCCEEECHHHHHHHHHHH
QTFTVDVSRESLNRTVGLTEPGEVNLEKALRAHDRLGGHIVSGHVDGLGTVTHFAPVGES
HEEEEEECHHHHCCEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHEECCCCC
HELRVLAPKALGKYLAHKGSITVNGVSLTVNAVADREDGCEFSINLIPHTVQMTTLRHLK
CCEEEECHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCCEEEEEECCCEEHHHHHHHCC
PGVKVNLEIDMIARYVERMLGASRDAASPLQ
CCCEEEEEHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]