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The map label for this gene is hemN [H]

Identifier: 238026433

GI number: 238026433

Start: 830927

End: 832318

Strand: Reverse

Name: hemN [H]

Synonym: bglu_1g07680

Alternate gene names: 238026433

Gene position: 832318-830927 (Counterclockwise)

Preceding gene: 238026437

Following gene: 238026432

Centisome position: 21.31

GC content: 69.61

Gene sequence:

>1392_bases
ATGACGTCCTGCTCCCGATCCCCGTTGTTCCGGCCCGATTTGCTGGCGAAGTACGCGATACCGGGCCCGCGGTACACCTC
GTACCCGACCGCGCTGCAGTTCGACGAGGCCTTCGATCCCGGCCATTACGCGCGCGCGGCGGCCGATCCCGGCGCGGCGG
CGAGCGAGCTGTCACTCTACGTCCACATCCCGTTCTGCGCGACGGCCTGCTTCTACTGCGGCTGCAACCGGATCGCGACC
GGCAACCGCGCGCACGCGGTGCCCTATCTCGAACGGCTCAAGCGCGAGCTGGCGCTGCAGGCCGAACGCTTCGACCCGGA
CCGCGTGATCACGCAGCTGCATTGGGGCGGCGGCACGCCGACCTTCCTGTCCGATGCGCAGACGGCCGAGCTGATGGCCG
CCACGCGCGCCTGCTTTCCGATCGCTGCGGACGACGAGGCCGAGATCTCGATCGAGATCGACCCGCGCACGGCCGTACCG
GCCACGCTCGCGCACCTGCGCATGCAGGGCTTCAACCGGCTGAGCCTCGGCGTGCAGGACGTCGATGCCGAGGTGCAGCG
CTCGATCAACCGGGTCCAGCCGATCGAGCGCACTGCCAGCCTGATTGCGGCGGCGCGGCTGGTCGGCTACCGCTCGATCA
GCGTCGACCTGATCTACGGGCTGCCGAGGCAGAGCGTGGCCACCTTCGCGCGCACGCTCGACACCGTGATCGAACTCGCG
CCGGACCGGATTTCCGTGTTCGGCTACGCGCATCTGCCGCAGCTGTTCAAGATGCAGCGCCGCATCGACGAGGCGCAGCT
GCCGCCGCCGGCCGAGCGCGTCGCGCTGCTCGGCCTCGCCATCGAAATGCTGACTGAGGCCGGCTACGTCTACATCGGCA
TGGATCATTTCGCGCGGCCCGGCGACGAGCTGGTGGCCGCGCAGCGCAACGGCACGCTGCAACGCAACTTCCAGGGCTAC
AGCACGCGCGCGGACACCGACCTGATCGGCGTGGGCGTGTCGTCGATCGGCAAGGTCGGCGACGTCTACGCGCAGAACGC
CAAGGACCTGGCCGCCTGGGGCGCGGCGCTCGACGCGGGCCGGCTGCCGATCGCGCGCGGCGTGCGGCTTTCGGTGGACG
ACCGCCTGCGCCGCGACGTCATCATGCGGCTCATGTGCAACCTGACGCTGCCGTTCGCCGAACTGGAAGCCGCCTACGGG
ATCCGCTTCGCCGAGCGCTTCACGCGCGAACTCGAAGCGCTCGGTGATTTCGAGCGCGATGGGCTGCTCACGATCGAACC
CGACCGGCTGACGATCCACCCGGTCGGGCGCCTGTTCGTGCGCAATATCGCGATGGCGTTCGACGCCTACCTGTCGACAG
CCAGCGCCGGGCGCTGCTCGCGCACCGTCTGA

Upstream 100 bases:

>100_bases
CGCATTGTGCCATCTCAAACTCCATCGAGACCGGACGCCCTCGATCGCGCGCCGCGCCACTAGACTGAACCGCGTCGCCC
GTCGCCTGTCGATTCCCATC

Downstream 100 bases:

>100_bases
AACCGGCGCGGGGCTCACCGGGCCGGCGGCCGGCGCCGCGGCCCGCCATCTGCGCTAAAGTGACGGTTTCCCGCCGCTCC
TTGCTCCACCACGATGCGCA

Product: coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTSCSRSPLFRPDLLAKYAIPGPRYTSYPTALQFDEAFDPGHYARAAADPGAAASELSLYVHIPFCATACFYCGCNRIAT
GNRAHAVPYLERLKRELALQAERFDPDRVITQLHWGGGTPTFLSDAQTAELMAATRACFPIAADDEAEISIEIDPRTAVP
ATLAHLRMQGFNRLSLGVQDVDAEVQRSINRVQPIERTASLIAAARLVGYRSISVDLIYGLPRQSVATFARTLDTVIELA
PDRISVFGYAHLPQLFKMQRRIDEAQLPPPAERVALLGLAIEMLTEAGYVYIGMDHFARPGDELVAAQRNGTLQRNFQGY
STRADTDLIGVGVSSIGKVGDVYAQNAKDLAAWGAALDAGRLPIARGVRLSVDDRLRRDVIMRLMCNLTLPFAELEAAYG
IRFAERFTRELEALGDFERDGLLTIEPDRLTIHPVGRLFVRNIAMAFDAYLSTASAGRCSRTV

Sequences:

>Translated_463_residues
MTSCSRSPLFRPDLLAKYAIPGPRYTSYPTALQFDEAFDPGHYARAAADPGAAASELSLYVHIPFCATACFYCGCNRIAT
GNRAHAVPYLERLKRELALQAERFDPDRVITQLHWGGGTPTFLSDAQTAELMAATRACFPIAADDEAEISIEIDPRTAVP
ATLAHLRMQGFNRLSLGVQDVDAEVQRSINRVQPIERTASLIAAARLVGYRSISVDLIYGLPRQSVATFARTLDTVIELA
PDRISVFGYAHLPQLFKMQRRIDEAQLPPPAERVALLGLAIEMLTEAGYVYIGMDHFARPGDELVAAQRNGTLQRNFQGY
STRADTDLIGVGVSSIGKVGDVYAQNAKDLAAWGAALDAGRLPIARGVRLSVDDRLRRDVIMRLMCNLTLPFAELEAAYG
IRFAERFTRELEALGDFERDGLLTIEPDRLTIHPVGRLFVRNIAMAFDAYLSTASAGRCSRTV
>Mature_462_residues
TSCSRSPLFRPDLLAKYAIPGPRYTSYPTALQFDEAFDPGHYARAAADPGAAASELSLYVHIPFCATACFYCGCNRIATG
NRAHAVPYLERLKRELALQAERFDPDRVITQLHWGGGTPTFLSDAQTAELMAATRACFPIAADDEAEISIEIDPRTAVPA
TLAHLRMQGFNRLSLGVQDVDAEVQRSINRVQPIERTASLIAAARLVGYRSISVDLIYGLPRQSVATFARTLDTVIELAP
DRISVFGYAHLPQLFKMQRRIDEAQLPPPAERVALLGLAIEMLTEAGYVYIGMDHFARPGDELVAAQRNGTLQRNFQGYS
TRADTDLIGVGVSSIGKVGDVYAQNAKDLAAWGAALDAGRLPIARGVRLSVDDRLRRDVIMRLMCNLTLPFAELEAAYGI
RFAERFTRELEALGDFERDGLLTIEPDRLTIHPVGRLFVRNIAMAFDAYLSTASAGRCSRTV

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=27.1375464684015, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI87082341, Length=451, Percent_Identity=48.5587583148559, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1789325, Length=284, Percent_Identity=30.2816901408451, Blast_Score=111, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004558
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 50869; Mature: 50738

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSCSRSPLFRPDLLAKYAIPGPRYTSYPTALQFDEAFDPGHYARAAADPGAAASELSLY
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCEEEEE
VHIPFCATACFYCGCNRIATGNRAHAVPYLERLKRELALQAERFDPDRVITQLHWGGGTP
EECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEECCCCCC
TFLSDAQTAELMAATRACFPIAADDEAEISIEIDPRTAVPATLAHLRMQGFNRLSLGVQD
CHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHCCHHH
VDAEVQRSINRVQPIERTASLIAAARLVGYRSISVDLIYGLPRQSVATFARTLDTVIELA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHC
PDRISVFGYAHLPQLFKMQRRIDEAQLPPPAERVALLGLAIEMLTEAGYVYIGMDHFARP
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCC
GDELVAAQRNGTLQRNFQGYSTRADTDLIGVGVSSIGKVGDVYAQNAKDLAAWGAALDAG
CHHHEEECCCCCEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCC
RLPIARGVRLSVDDRLRRDVIMRLMCNLTLPFAELEAAYGIRFAERFTRELEALGDFERD
CCCHHCCCEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLLTIEPDRLTIHPVGRLFVRNIAMAFDAYLSTASAGRCSRTV
CEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TSCSRSPLFRPDLLAKYAIPGPRYTSYPTALQFDEAFDPGHYARAAADPGAAASELSLY
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCEEEEE
VHIPFCATACFYCGCNRIATGNRAHAVPYLERLKRELALQAERFDPDRVITQLHWGGGTP
EECHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHEEECCCCCC
TFLSDAQTAELMAATRACFPIAADDEAEISIEIDPRTAVPATLAHLRMQGFNRLSLGVQD
CHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHCCHHH
VDAEVQRSINRVQPIERTASLIAAARLVGYRSISVDLIYGLPRQSVATFARTLDTVIELA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHC
PDRISVFGYAHLPQLFKMQRRIDEAQLPPPAERVALLGLAIEMLTEAGYVYIGMDHFARP
CCCEEEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCC
GDELVAAQRNGTLQRNFQGYSTRADTDLIGVGVSSIGKVGDVYAQNAKDLAAWGAALDAG
CHHHEEECCCCCEEECCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCC
RLPIARGVRLSVDDRLRRDVIMRLMCNLTLPFAELEAAYGIRFAERFTRELEALGDFERD
CCCHHCCCEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLLTIEPDRLTIHPVGRLFVRNIAMAFDAYLSTASAGRCSRTV
CEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9767567; 10984043 [H]