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The map label for this gene is kbl [C]

Identifier: 238026333

GI number: 238026333

Start: 724100

End: 725425

Strand: Direct

Name: kbl [C]

Synonym: bglu_1g06670

Alternate gene names: 238026333

Gene position: 724100-725425 (Clockwise)

Preceding gene: 238026332

Following gene: 238026334

Centisome position: 18.54

GC content: 70.74

Gene sequence:

>1326_bases
ATGGGACTGGGAGATCATCTCCGGCAGCAATTGGCTGCAAAGGCGCTCAAGCGCCAACTGGAGCGCGTGACCGAGGGCGG
CGCGGACACCGCGCCGGCGCCGGCGCCGGCCGCGGCGGGCGTGCATGCCTCGCCGCGCAGCCGCTTCGAGTCGATGCCGC
AATACCAGCAGCTCAGGATCATGCGCGAGATGGGCGAGACGCTCGGCGTCGAATCGCCGTTCTTCCGCGTCCATGACGGG
CTTGCCGGCGCGACCACGCTGATCGGCGGGCGCGAGTACCTGAACTACGCGAACTACAACTACCTGGGCCTGGCGGGCGA
CGCCACGGTGACGGCGCACGCCAAGCAGGCCATCGACCGCTACGGCACCTCGGCCTCGGCGAGCCGCATGGTGGCGGGCG
AGCGGCCCGTGCAGCGCGATCTCGAGCACGCGCTCGCGGCGTTCTACGGGACCGACGACTGCGTGGTGTTCGTGAGCGGC
CACGCCACCAACGTGACCGTGATCGGCTCGCTGTTCGGGCAGGGCGACCTGATCGTCCATGATTCGCTCGCGCACAACAG
CATCGTGCAGGGCGCGCAGCTGAGCGGCGCCAAGCGCCTGAGCTTCCCGCACAACGACTGGCGCGCGCTCGACGCGCTGC
TGGCGCGCGTGCGCCACGAGTATCGCAACGTGCTGATCGCGATCGAGGGGCTCTACAGCATGGACGGCGATTTCCCCGAT
CTGCCGAAGTTCGTCGAGATCCGCAAGCGCCACGGCGCGTTCCTGATGGTTGACGAGGCGCATTCGCTCGGCGTGCTCGG
CGCCACCGGGCGCGGCATCCGCGAGCATTTCGGGGTGGCCGCCGAGGACGTCGACCTGTGGATGGGCACGCTCAGCAAGA
CGCTGGCCGGCTGCGGCGGCTTCATCGCCGGCTGCCAGCCGCTCACCGACATGCTGCGCCATCTGGCGCCGGGCTTCCTC
TACAGCGTCGGTCTCGCGCCGGTGCTCGCGGCCGCCTCGCTGAGCGCGCTCGAGATCCTGCAGCGCGAGCCGCAGCGCGT
CGCGCAGCTGCGCGAGCGCGGCCGGCAGTTCCTCGACGAGGCGCGCGCCGCGGGCCTCGACACCGGCACCAGCGCAGGCT
ACGCGGTGGTGCCGGTGATCACCGGCAGCTCGCTGAAGGCGGCACGCTGGGCCAACGCGCTGTTCGACGAGGGCATCAAC
GTGCAGCCGATCTTCTATCCGGCCGTCGAGGAAAAAGCGGCGCGGCTGCGCTTCTTCATCTGCTCGACGCACGAGCCCGG
GCAGATCACGCGCACCGTGGCCGCGCTGGCCCGGCTCGCGCGCTAG

Upstream 100 bases:

>100_bases
CGGCTCGTCGATGCGCTGCTGTCCAGCCCCGATGCATGGGAGTGGGCCGAATTCGCGGCGTAACATAGCGAACTTGATCA
GGCTACGGGCGAACGAATCG

Downstream 100 bases:

>100_bases
GCAGCGCAATGGCGGCCCCGCTTGCCGGGTGGACCTTCCGTGCCGCGCGTCCCGAGGATGCCGCGGCCTGCGCGCCGCTG
ATCCTCGCCTCGGGCGTGCG

Product: glycine C-acetyltransferase

Products: NA

Alternate protein names: AONS/AKB ligase; 7-keto-8-amino-pelargonic acid synthase; 7-KAP synthase; KAPA synthase; 8-amino-7-ketopelargonate synthase; Alpha-oxoamine synthase; L-alanine--pimeloyl-CoA ligase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MGLGDHLRQQLAAKALKRQLERVTEGGADTAPAPAPAAAGVHASPRSRFESMPQYQQLRIMREMGETLGVESPFFRVHDG
LAGATTLIGGREYLNYANYNYLGLAGDATVTAHAKQAIDRYGTSASASRMVAGERPVQRDLEHALAAFYGTDDCVVFVSG
HATNVTVIGSLFGQGDLIVHDSLAHNSIVQGAQLSGAKRLSFPHNDWRALDALLARVRHEYRNVLIAIEGLYSMDGDFPD
LPKFVEIRKRHGAFLMVDEAHSLGVLGATGRGIREHFGVAAEDVDLWMGTLSKTLAGCGGFIAGCQPLTDMLRHLAPGFL
YSVGLAPVLAAASLSALEILQREPQRVAQLRERGRQFLDEARAAGLDTGTSAGYAVVPVITGSSLKAARWANALFDEGIN
VQPIFYPAVEEKAARLRFFICSTHEPGQITRTVAALARLAR

Sequences:

>Translated_441_residues
MGLGDHLRQQLAAKALKRQLERVTEGGADTAPAPAPAAAGVHASPRSRFESMPQYQQLRIMREMGETLGVESPFFRVHDG
LAGATTLIGGREYLNYANYNYLGLAGDATVTAHAKQAIDRYGTSASASRMVAGERPVQRDLEHALAAFYGTDDCVVFVSG
HATNVTVIGSLFGQGDLIVHDSLAHNSIVQGAQLSGAKRLSFPHNDWRALDALLARVRHEYRNVLIAIEGLYSMDGDFPD
LPKFVEIRKRHGAFLMVDEAHSLGVLGATGRGIREHFGVAAEDVDLWMGTLSKTLAGCGGFIAGCQPLTDMLRHLAPGFL
YSVGLAPVLAAASLSALEILQREPQRVAQLRERGRQFLDEARAAGLDTGTSAGYAVVPVITGSSLKAARWANALFDEGIN
VQPIFYPAVEEKAARLRFFICSTHEPGQITRTVAALARLAR
>Mature_440_residues
GLGDHLRQQLAAKALKRQLERVTEGGADTAPAPAPAAAGVHASPRSRFESMPQYQQLRIMREMGETLGVESPFFRVHDGL
AGATTLIGGREYLNYANYNYLGLAGDATVTAHAKQAIDRYGTSASASRMVAGERPVQRDLEHALAAFYGTDDCVVFVSGH
ATNVTVIGSLFGQGDLIVHDSLAHNSIVQGAQLSGAKRLSFPHNDWRALDALLARVRHEYRNVLIAIEGLYSMDGDFPDL
PKFVEIRKRHGAFLMVDEAHSLGVLGATGRGIREHFGVAAEDVDLWMGTLSKTLAGCGGFIAGCQPLTDMLRHLAPGFLY
SVGLAPVLAAASLSALEILQREPQRVAQLRERGRQFLDEARAAGLDTGTSAGYAVVPVITGSSLKAARWANALFDEGINV
QPIFYPAVEEKAARLRFFICSTHEPGQITRTVAALARLAR

Specific function: Catalyzes the decarboxylative condensation of pimeloyl- CoA and L-alanine to produce 8-amino-7-oxononanoate (AON), coenzyme A and/or converts 2-amino-3-ketobutyrate to glycine and acetyl-CoA [H]

COG id: COG0156

COG function: function code H; 7-keto-8-aminopelargonate synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI119220554, Length=364, Percent_Identity=32.6923076923077, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI4758668, Length=346, Percent_Identity=32.3699421965318, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI7657118, Length=372, Percent_Identity=31.7204301075269, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI284448556, Length=349, Percent_Identity=32.0916905444126, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI5454084, Length=346, Percent_Identity=30.3468208092486, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI83977442, Length=355, Percent_Identity=27.6056338028169, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI83977440, Length=355, Percent_Identity=27.6056338028169, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI83977444, Length=355, Percent_Identity=27.6056338028169, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI4502025, Length=349, Percent_Identity=29.512893982808, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI40316939, Length=349, Percent_Identity=29.512893982808, Blast_Score=131, Evalue=1e-30,
Organism=Escherichia coli, GI1790046, Length=389, Percent_Identity=34.4473007712082, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786993, Length=358, Percent_Identity=30.1675977653631, Blast_Score=139, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI32566772, Length=363, Percent_Identity=33.6088154269972, Blast_Score=215, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI17560914, Length=366, Percent_Identity=30.8743169398907, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17560912, Length=366, Percent_Identity=30.8743169398907, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71994529, Length=370, Percent_Identity=30.8108108108108, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71982625, Length=285, Percent_Identity=35.4385964912281, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71982617, Length=285, Percent_Identity=35.4385964912281, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6320267, Length=341, Percent_Identity=31.9648093841642, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320438, Length=349, Percent_Identity=29.2263610315186, Blast_Score=139, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6323954, Length=275, Percent_Identity=27.6363636363636, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24662918, Length=352, Percent_Identity=30.3977272727273, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI17136286, Length=363, Percent_Identity=29.4765840220386, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24653280, Length=290, Percent_Identity=31.0344827586207, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24653276, Length=290, Percent_Identity=31.0344827586207, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24653278, Length=290, Percent_Identity=31.0344827586207, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI17137420, Length=408, Percent_Identity=28.4313725490196, Blast_Score=148, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR004723
- InterPro:   IPR010962
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.3.1.29; =2.3.1.47 [H]

Molecular weight: Translated: 47482; Mature: 47350

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGDHLRQQLAAKALKRQLERVTEGGADTAPAPAPAAAGVHASPRSRFESMPQYQQLRI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
MREMGETLGVESPFFRVHDGLAGATTLIGGREYLNYANYNYLGLAGDATVTAHAKQAIDR
HHHHHHHHCCCCCHHHHHCCCCHHHHHHCCHHHHHCCCCCEEEECCCCEEHHHHHHHHHH
YGTSASASRMVAGERPVQRDLEHALAAFYGTDDCVVFVSGHATNVTVIGSLFGQGDLIVH
CCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEHHCCCCCEEEE
DSLAHNSIVQGAQLSGAKRLSFPHNDWRALDALLARVRHEYRNVLIAIEGLYSMDGDFPD
CCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCC
LPKFVEIRKRHGAFLMVDEAHSLGVLGATGRGIREHFGVAAEDVDLWMGTLSKTLAGCGG
CHHHHHHHHHCCCEEEEECCCCCCEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCH
FIAGCQPLTDMLRHLAPGFLYSVGLAPVLAAASLSALEILQREPQRVAQLRERGRQFLDE
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ARAAGLDTGTSAGYAVVPVITGSSLKAARWANALFDEGINVQPIFYPAVEEKAARLRFFI
HHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHEEEEE
CSTHEPGQITRTVAALARLAR
ECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GLGDHLRQQLAAKALKRQLERVTEGGADTAPAPAPAAAGVHASPRSRFESMPQYQQLRI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHH
MREMGETLGVESPFFRVHDGLAGATTLIGGREYLNYANYNYLGLAGDATVTAHAKQAIDR
HHHHHHHHCCCCCHHHHHCCCCHHHHHHCCHHHHHCCCCCEEEECCCCEEHHHHHHHHHH
YGTSASASRMVAGERPVQRDLEHALAAFYGTDDCVVFVSGHATNVTVIGSLFGQGDLIVH
CCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEHHCCCCCEEEE
DSLAHNSIVQGAQLSGAKRLSFPHNDWRALDALLARVRHEYRNVLIAIEGLYSMDGDFPD
CCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEHHHHCCCCCCC
LPKFVEIRKRHGAFLMVDEAHSLGVLGATGRGIREHFGVAAEDVDLWMGTLSKTLAGCGG
CHHHHHHHHHCCCEEEEECCCCCCEECCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCH
FIAGCQPLTDMLRHLAPGFLYSVGLAPVLAAASLSALEILQREPQRVAQLRERGRQFLDE
HHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ARAAGLDTGTSAGYAVVPVITGSSLKAARWANALFDEGINVQPIFYPAVEEKAARLRFFI
HHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHEEEEE
CSTHEPGQITRTVAALARLAR
ECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA