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The map label for this gene is lpxC [H]

Identifier: 238026332

GI number: 238026332

Start: 723139

End: 724062

Strand: Direct

Name: lpxC [H]

Synonym: bglu_1g06660

Alternate gene names: 238026332

Gene position: 723139-724062 (Clockwise)

Preceding gene: 339905958

Following gene: 238026333

Centisome position: 18.51

GC content: 75.65

Gene sequence:

>924_bases
ATGACGAGCACCGCGCCGGCCGGCTGGCAGGCCACGCAGGGCACGCTCGCGAGCGAGCTCGTGCTGGACGGCCACGGCCT
GCACACCGGCCGGCGCGTGCGGGTGCGGATCCTGCCCGCGGCGGGCAGGCAGCCTGCCACGCGCGGCATCCGGTTTCGCC
GCCTGGACGGCGGCCGGGAGCTGGCCAGCTTCGCGGTCGATCCGGCGTTGCGCCGTGCCCAGCCGCTTTGCACCATGCTG
CGCGGCCCCGACGGCGTGGGCGTGCGCACCGTCGAGCACCTGCTCGCGGCGCTGCTCGCCTGCGAGATCGACCATGCCAC
GGTCGAGCTCGACGCCGAGGAGGTGCCGATCCTCGACGGCAGCGCCGCGCCCTGGATCGCGGCGCTGCGCGCGACCGGCC
GCCACGCGCTGGCCGCGCCGAAGCGCTTCATCCGCGTGACGCGTGCGCTCGCGGTGACCGACGGCGCGGGCGGCGCGCGC
CGCGAGATGCGGCTCGAACCCGCGCCGCGCTACGAGATGAGCGTGCGCAACGACCTGAAGGGCTTCGGCGAGATGCACTG
GGCCGGCGAGATGACGCCGGCCGCGTTCGCCGCCGAGATCGCGCCGTCGCGCTCCTACGGGCGCGTCAAGTGGGCGGTGC
CGGCGATCGTCGCGGGCTACCTGCGCGGCGTGCCGATCCTGCGCGGCGCGCGGCCCTCCTGCACCGCGTCGATCGTCGGC
CGCCGCGTGCTGGGCGGCATGCGCCTGCCCGACGAGTTCGTGCGCCACCGCGTGCTCGACCTGGTCGGCGACCTGGCGAT
GGCCGGCGCGCCGCTGCTCGCGCGCGTCTCGGCGTTGCGGCCGAGCCACGAAATGAACTTCCGGCTCGTCGATGCGCTGC
TGTCCAGCCCCGATGCATGGGAGTGGGCCGAATTCGCGGCGTAA

Upstream 100 bases:

>100_bases
TGGCCGCGAAGCACGCGCTCGACAGCGAGGCCAAGGCCGCGCTGAAGGCCGCCGCCAACGATCCGGTGGGCGGCAAGAAG
CCGAGGCTGGAGGTGGCGCA

Downstream 100 bases:

>100_bases
CATAGCGAACTTGATCAGGCTACGGGCGAACGAATCGATGGGACTGGGAGATCATCTCCGGCAGCAATTGGCTGCAAAGG
CGCTCAAGCGCCAACTGGAG

Product: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

Products: UDP-3-O-(3-Hydroxytetradecanoyl)- Glucosamine; Acetate. [C]

Alternate protein names: UDP-3-O-acyl-GlcNAc deacetylase [H]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTSTAPAGWQATQGTLASELVLDGHGLHTGRRVRVRILPAAGRQPATRGIRFRRLDGGRELASFAVDPALRRAQPLCTML
RGPDGVGVRTVEHLLAALLACEIDHATVELDAEEVPILDGSAAPWIAALRATGRHALAAPKRFIRVTRALAVTDGAGGAR
REMRLEPAPRYEMSVRNDLKGFGEMHWAGEMTPAAFAAEIAPSRSYGRVKWAVPAIVAGYLRGVPILRGARPSCTASIVG
RRVLGGMRLPDEFVRHRVLDLVGDLAMAGAPLLARVSALRPSHEMNFRLVDALLSSPDAWEWAEFAA

Sequences:

>Translated_307_residues
MTSTAPAGWQATQGTLASELVLDGHGLHTGRRVRVRILPAAGRQPATRGIRFRRLDGGRELASFAVDPALRRAQPLCTML
RGPDGVGVRTVEHLLAALLACEIDHATVELDAEEVPILDGSAAPWIAALRATGRHALAAPKRFIRVTRALAVTDGAGGAR
REMRLEPAPRYEMSVRNDLKGFGEMHWAGEMTPAAFAAEIAPSRSYGRVKWAVPAIVAGYLRGVPILRGARPSCTASIVG
RRVLGGMRLPDEFVRHRVLDLVGDLAMAGAPLLARVSALRPSHEMNFRLVDALLSSPDAWEWAEFAA
>Mature_306_residues
TSTAPAGWQATQGTLASELVLDGHGLHTGRRVRVRILPAAGRQPATRGIRFRRLDGGRELASFAVDPALRRAQPLCTMLR
GPDGVGVRTVEHLLAALLACEIDHATVELDAEEVPILDGSAAPWIAALRATGRHALAAPKRFIRVTRALAVTDGAGGARR
EMRLEPAPRYEMSVRNDLKGFGEMHWAGEMTPAAFAAEIAPSRSYGRVKWAVPAIVAGYLRGVPILRGARPSCTASIVGR
RVLGGMRLPDEFVRHRVLDLVGDLAMAGAPLLARVSALRPSHEMNFRLVDALLSSPDAWEWAEFAA

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0774

COG function: function code M; UDP-3-O-acyl-N-acetylglucosamine deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxC family [H]

Homologues:

Organism=Escherichia coli, GI1786285, Length=299, Percent_Identity=32.4414715719064, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR004463
- InterPro:   IPR011334
- InterPro:   IPR015870 [H]

Pfam domain/function: PF03331 LpxC [H]

EC number: 3.5.1.- [C]

Molecular weight: Translated: 33058; Mature: 32926

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTAPAGWQATQGTLASELVLDGHGLHTGRRVRVRILPAAGRQPATRGIRFRRLDGGRE
CCCCCCCCCCCCCCHHHHHHEECCCCCCCCCEEEEEEEECCCCCCHHHCEEEEECCCCHH
LASFAVDPALRRAQPLCTMLRGPDGVGVRTVEHLLAALLACEIDHATVELDAEEVPILDG
HHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECC
SAAPWIAALRATGRHALAAPKRFIRVTRALAVTDGAGGARREMRLEPAPRYEMSVRNDLK
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHH
GFGEMHWAGEMTPAAFAAEIAPSRSYGRVKWAVPAIVAGYLRGVPILRGARPSCTASIVG
HHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RRVLGGMRLPDEFVRHRVLDLVGDLAMAGAPLLARVSALRPSHEMNFRLVDALLSSPDAW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
EWAEFAA
CHHHHCC
>Mature Secondary Structure 
TSTAPAGWQATQGTLASELVLDGHGLHTGRRVRVRILPAAGRQPATRGIRFRRLDGGRE
CCCCCCCCCCCCCHHHHHHEECCCCCCCCCEEEEEEEECCCCCCHHHCEEEEECCCCHH
LASFAVDPALRRAQPLCTMLRGPDGVGVRTVEHLLAALLACEIDHATVELDAEEVPILDG
HHHHHHCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECC
SAAPWIAALRATGRHALAAPKRFIRVTRALAVTDGAGGARREMRLEPAPRYEMSVRNDLK
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHH
GFGEMHWAGEMTPAAFAAEIAPSRSYGRVKWAVPAIVAGYLRGVPILRGARPSCTASIVG
HHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
RRVLGGMRLPDEFVRHRVLDLVGDLAMAGAPLLARVSALRPSHEMNFRLVDALLSSPDAW
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCC
EWAEFAA
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-3-O-(3-Hydroxytetradecanoyl)-N- Acetylglucosamine; H2O [C]

Specific reaction: UDP-3-O-(3-Hydroxytetradecanoyl)-N- Acetylglucosamine + H2O = UDP-3-O-(3-Hydroxytetradecanoyl)- Glucosamine + Acetate. [C]

General reaction: Hydrolase; Acting on carbon-nitrogen bonds, other than peptide bonds; In linear amides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA