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The map label for this gene is dgk [H]

Identifier: 238026304

GI number: 238026304

Start: 680466

End: 681149

Strand: Reverse

Name: dgk [H]

Synonym: bglu_1g06380

Alternate gene names: 238026304

Gene position: 681149-680466 (Counterclockwise)

Preceding gene: 238026305

Following gene: 238026303

Centisome position: 17.44

GC content: 70.18

Gene sequence:

>684_bases
ATGAACGCGACGCCGCTGACCGTCACGCCGCCCGACCCGCGCCCGCCCCACCGCTACCTCGCGATCGAGGGGCCGATCGG
CGTCGGCAAGACCTCGCTAGCCACGCTGCTGGCCGAGCGCTGGGGCATGGACACGCTCTTCGAACGCCCGCAGGACAATC
CGTTTCTCGAACGCTTCTACCGCGAGGGCGCACGCTACGCGCTGCCGGCGCAGCTCGCGTTCGCGCTGCAGCGCGCGCGC
CAGACCGGCGGGATCGCCGCCGCGCAGGCCGCCGGCGCCGCGCTGGTGGCCGATTTCATGCCGCAGAAGAGCGAGATCTT
CGCGCGCCTGACGCTCGCCGACGACGAATGGCAGCTCTACCGCACGCTGGCCGAGCGCATCGACGCGCCCGCGCCCGCGC
CCGACCTGGTGGTCTACCTGCAGGCGAGCCCCGAGGTGCTGTACGCGCGGATCCAGAAACGCGGCATCGCAGCGGAACTG
CAGATCGGCGACGCCTACCTGCGCGCGCTGTGCGACGCCTACAACGAATTCTTCTATCACTACGACCGCACGCCGGTCCT
CACCGTCGCGGCGGAACACCTGAATCCGCTCGACTCGCCGGACGATCTTGCCTTGCTGATGACGCGCATCGAGACGATGC
GCGGGCGCAAGGAATCCTTCGTCAAGGGCGGCGTCGGCCGCTGA

Upstream 100 bases:

>100_bases
AGGCGTTCCTCGCCGCGGTGGCCGACCAGCGCATCGAGAAGGTGCAGACCTGCCAGTGCCTGCTGGCGATGAAGAGCGCG
AACGAGTCGCGCCGCTGCCG

Downstream 100 bases:

>100_bases
GGCGGTTCGCGGCGCCGCCTGTTTTCTCCACGAAACCGGACCCCCCATGACCTACCTCCAGGAATCGAGCCGCGCGGCCG
TGACCGTGCCGAAACTGCAG

Product: deoxynucleoside kinase family protein

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNATPLTVTPPDPRPPHRYLAIEGPIGVGKTSLATLLAERWGMDTLFERPQDNPFLERFYREGARYALPAQLAFALQRAR
QTGGIAAAQAAGAALVADFMPQKSEIFARLTLADDEWQLYRTLAERIDAPAPAPDLVVYLQASPEVLYARIQKRGIAAEL
QIGDAYLRALCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLMTRIETMRGRKESFVKGGVGR

Sequences:

>Translated_227_residues
MNATPLTVTPPDPRPPHRYLAIEGPIGVGKTSLATLLAERWGMDTLFERPQDNPFLERFYREGARYALPAQLAFALQRAR
QTGGIAAAQAAGAALVADFMPQKSEIFARLTLADDEWQLYRTLAERIDAPAPAPDLVVYLQASPEVLYARIQKRGIAAEL
QIGDAYLRALCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLMTRIETMRGRKESFVKGGVGR
>Mature_227_residues
MNATPLTVTPPDPRPPHRYLAIEGPIGVGKTSLATLLAERWGMDTLFERPQDNPFLERFYREGARYALPAQLAFALQRAR
QTGGIAAAQAAGAALVADFMPQKSEIFARLTLADDEWQLYRTLAERIDAPAPAPDLVVYLQASPEVLYARIQKRGIAAEL
QIGDAYLRALCDAYNEFFYHYDRTPVLTVAAEHLNPLDSPDDLALLMTRIETMRGRKESFVKGGVGR

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 25217; Mature: 25217

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATPLTVTPPDPRPPHRYLAIEGPIGVGKTSLATLLAERWGMDTLFERPQDNPFLERFY
CCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHH
REGARYALPAQLAFALQRARQTGGIAAAQAAGAALVADFMPQKSEIFARLTLADDEWQLY
HCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHEEEEEECCCHHHHH
RTLAERIDAPAPAPDLVVYLQASPEVLYARIQKRGIAAELQIGDAYLRALCDAYNEFFYH
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHH
YDRTPVLTVAAEHLNPLDSPDDLALLMTRIETMRGRKESFVKGGVGR
CCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCC
>Mature Secondary Structure
MNATPLTVTPPDPRPPHRYLAIEGPIGVGKTSLATLLAERWGMDTLFERPQDNPFLERFY
CCCCCCEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHH
REGARYALPAQLAFALQRARQTGGIAAAQAAGAALVADFMPQKSEIFARLTLADDEWQLY
HCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHEEEEEECCCHHHHH
RTLAERIDAPAPAPDLVVYLQASPEVLYARIQKRGIAAELQIGDAYLRALCDAYNEFFYH
HHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHH
YDRTPVLTVAAEHLNPLDSPDDLALLMTRIETMRGRKESFVKGGVGR
CCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]