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The map label for this gene is ubiA [H]

Identifier: 238026279

GI number: 238026279

Start: 645484

End: 646347

Strand: Direct

Name: ubiA [H]

Synonym: bglu_1g06120

Alternate gene names: 238026279

Gene position: 645484-646347 (Clockwise)

Preceding gene: 238026278

Following gene: 238026286

Centisome position: 16.52

GC content: 65.74

Gene sequence:

>864_bases
ATGTTTGCCCGCTTCCCCCTCTATCTGAAGCTGATCCGGATGGACAAGCCGATCGGCAGTCTGCTGCTGCTGTGGCCGAC
GCTGAACGCGCTGTGGATTGCCTCGAACGGGCGGCCCGCGCCGCTGCTGCTGGTGATCTTCATCGTCGGCACGCTGCTGA
TGCGTTCGGCCGGCTGCGCGATCAACGATTACGCCGACCGCGATTTCGACAGCCACGTGAAACGCACGGTGGACCGGCCG
CTGGCCTCGGGCAAGATCCGCGCGTGGGAGGCGGTGGCGATCGCGGCGGGCCTCGCGATCGCCGCGTTCCTGCTGATCCT
GCCGCTCAACCTGCTGACCAAGGAACTGTCGGTGGTGGCCGTGATCGTTGCCGGCACCTATCCGTTCATGAAGCGTTTCT
TCGCGATCCCGCAGGCCTATCTCGGCATCGCGTTCGGCTTCGGGATTCCGATGGCGTTCGCGGCCGTGCAGGACACCGTG
CCGCTGCTGGCCTGGGTGATGCTGGCCGCCAACGTGTTCTGGTCGGTTGCCTACGACACCGCCTACGCGATGGTCGACCG
CGACGACGACTTGAAGATCGGCATGCGCACCTCGGCGATCACCTTTGGCCGCCACGACGTGCTGGCCATCATGCTCTGCT
ATGCGATGGTGTTCGCGATCTACCTCTGGGTCGGCCTGGTCGAGCGCTTCGGGCCGCTCTACTGGCTGGGCTGGGCCGTC
GCGCTCGGCTGCTCGGTCTACCATTACACGCTGATCAAGGATCGCGACCGCATGAAGTGTTTCGCCGCGTTCCTGCACAA
CAACTGGCTCGGCGGCGCGCTGTTCGCCGGGATCGCCGCGCACTATGCGGTGGCCGCGCGCTGA

Upstream 100 bases:

>100_bases
CCGCGCGCTTGCCTCGGCCGGTCGGCCGCCGCGCACGGCACGGGGCCGCACCGCCATGCGCGTTACAATGCCGCCATCGT
TTCCGCGGTGGAATCCCGAC

Downstream 100 bases:

>100_bases
GCCTGGCGGAGCGCTGCGGCCGGTGAGGCGAAAACGACGAAGCGGCCGGAAAGGCCGCTTCGTCGTTTTCGGCGCGCATA
GCGCGGGAGCATGCCGTTCA

Product: 4-hydroxybenzoate octaprenyltransferase

Products: @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MFARFPLYLKLIRMDKPIGSLLLLWPTLNALWIASNGRPAPLLLVIFIVGTLLMRSAGCAINDYADRDFDSHVKRTVDRP
LASGKIRAWEAVAIAAGLAIAAFLLILPLNLLTKELSVVAVIVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PLLAWVMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAMVFAIYLWVGLVERFGPLYWLGWAV
ALGCSVYHYTLIKDRDRMKCFAAFLHNNWLGGALFAGIAAHYAVAAR

Sequences:

>Translated_287_residues
MFARFPLYLKLIRMDKPIGSLLLLWPTLNALWIASNGRPAPLLLVIFIVGTLLMRSAGCAINDYADRDFDSHVKRTVDRP
LASGKIRAWEAVAIAAGLAIAAFLLILPLNLLTKELSVVAVIVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PLLAWVMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAMVFAIYLWVGLVERFGPLYWLGWAV
ALGCSVYHYTLIKDRDRMKCFAAFLHNNWLGGALFAGIAAHYAVAAR
>Mature_287_residues
MFARFPLYLKLIRMDKPIGSLLLLWPTLNALWIASNGRPAPLLLVIFIVGTLLMRSAGCAINDYADRDFDSHVKRTVDRP
LASGKIRAWEAVAIAAGLAIAAFLLILPLNLLTKELSVVAVIVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTV
PLLAWVMLAANVFWSVAYDTAYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAMVFAIYLWVGLVERFGPLYWLGWAV
ALGCSVYHYTLIKDRDRMKCFAAFLHNNWLGGALFAGIAAHYAVAAR

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=276, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1790473, Length=273, Percent_Identity=51.6483516483517, Blast_Score=269, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=32.9861111111111, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32565247, Length=288, Percent_Identity=31.5972222222222, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=28.9855072463768, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI32565245, Length=137, Percent_Identity=40.8759124087591, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32565243, Length=133, Percent_Identity=40.6015037593985, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324370, Length=275, Percent_Identity=32, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355567, Length=280, Percent_Identity=33.9285714285714, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.- [C]

Molecular weight: Translated: 31764; Mature: 31764

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFARFPLYLKLIRMDKPIGSLLLLWPTLNALWIASNGRPAPLLLVIFIVGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
INDYADRDFDSHVKRTVDRPLASGKIRAWEAVAIAAGLAIAAFLLILPLNLLTKELSVVA
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPLLAWVMLAANVFWSVAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAMVFAIYLWVGLVERFGPLYWLGWAV
HHHEECCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ALGCSVYHYTLIKDRDRMKCFAAFLHNNWLGGALFAGIAAHYAVAAR
HHHHHHHEEHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFARFPLYLKLIRMDKPIGSLLLLWPTLNALWIASNGRPAPLLLVIFIVGTLLMRSAGCA
CCCCHHHHHHHHHHCCCHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
INDYADRDFDSHVKRTVDRPLASGKIRAWEAVAIAAGLAIAAFLLILPLNLLTKELSVVA
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIVAGTYPFMKRFFAIPQAYLGIAFGFGIPMAFAAVQDTVPLLAWVMLAANVFWSVAYDT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYAMVDRDDDLKIGMRTSAITFGRHDVLAIMLCYAMVFAIYLWVGLVERFGPLYWLGWAV
HHHEECCCCCCEEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
ALGCSVYHYTLIKDRDRMKCFAAFLHNNWLGGALFAGIAAHYAVAAR
HHHHHHHEEHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-Hydroxybenzoate; Farnesylfarnesylgeraniol [C]

Specific reaction: 4-Hydroxybenzoate + Farnesylfarnesylgeraniol = @OCTA07.txt*3-Octaprenyl-4-Hydroxybenzoate!. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA