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The map label for this gene is maeB [H]

Identifier: 238026198

GI number: 238026198

Start: 556687

End: 558987

Strand: Direct

Name: maeB [H]

Synonym: bglu_1g05290

Alternate gene names: 238026198

Gene position: 556687-558987 (Clockwise)

Preceding gene: 238026194

Following gene: 238026199

Centisome position: 14.25

GC content: 66.75

Gene sequence:

>2301_bases
ATGTCCACCAAGTCCTCCCCGAAAGCCGATTTGCGCGCAGCCGCCCTCGATTACCACGAATTCCCGACCCCGGGCAAAAT
CGCCGTCCAGCCGACCAAGCAGATGATCAACCAGCGCGATCTCGCGCTGGCGTATTCGCCCGGCGTCGCGTTCGCCTGCG
AGGAGATCGTCGAGAATCCGCTCAATGCCGCGCGCTTCACGTCCCGCAGCAACCTGGTCGGCGTCGTCACCAACGGCACC
GCGGTGCTGGGCCTCGGCAACATCGGCCCGCTCGCGTCGAAGCCGGTGATGGAGGGCAAGGCCGCGCTGTTCAAGAAGTT
CGCCGGCATCGACGTGTTCGACATCGAACTGAACGAATCGGACCCGCACAAGCTGGTGGAGGTGATCGCCGCGCTCGAGC
CGACCTTCGGCGGCATCAACCTCGAGGACATCAAGGCACCGGACTGCTTCATCGTCGAGCGCGAATGCCGCAAGCGCATG
AAGATCCCGGTATTCCACGACGACCAGCACGGCACCGCGATCGTGGTTGCCGCCGCGGTCACCAACGGCCTCAAGGTGGT
GGGCAAGGACATCAAGCAGGTCAAGCTGGTCGCCTCGGGCGCGGGCGCCGCGGCGCTCGCCTGCCTGGACCTGCTGGTCG
ACATCGGCCTGCCGCTCGAGAACATCTTCGTCACGGACCTGGCCGGCGTCGTCTACCGGGGCCGCGCCGAGCTGATGGAC
CCGGACAAGGAGCGGTTCGCGCGCGAGACCGACGCGCGCACGCTGGCCGAGGTGATCGAGGGCGCCGACATCTTCCTCGG
CCTGTCGGCCGCCGGCGTGCTGAAGCAGGAGATGGTCAAGGGCATGGCCGAGCGCCCGCTGATCCTCGCGCTGGCCAACC
CGACGCCGGAAATCCTGCCGGAAGTCGCGCACGAGGTGCGCCCCGACGCGATTCTCGCGACCGGCCGCACCGACTATCCG
AATCAGGTCAACAACGTCCTCTGCTTCCCGTTCATCTTCCGCGGCGCGCTCGACGTGGGCGCGACCACGATCACGCGCGA
GATGGAGATCGCCGCCGTCAACGCGATCGCCGAGCTTGCGCAGCAGGAGCAGAGCGACATCGTCGCCACGGCCTACGCGA
TCGAGGATCTCTCGTTCGGGCCGGAATACCTGATCCCGAAGCCGTTCGATCCGCGCCTGATCGTCAAAATCGCGCCGGCC
GTCGCGAAGGCCGCGATGGAGGGCGGCGTGGCGACGCGCCCGATCGAGGACATGGACGCCTACGTCCAGCACCTGCAGCA
GTTCGTCTATCACAGCGGCAACACCATGAAGCCGGTGTTCCAGGCCGCGCGCAGCGCCCCGCTGGAGAAGAAGCGCGTGG
TGTTCGCCGAGGGCGAGGAGGAGCGCGTGCTGCGCGCGGTGCAGATCCTCGTCGACGAGCACGTCGCCAAGCCGATCCTG
ATCGGCCGCCCGCACGTGATCGAGAACCGCATCAAGCGCTTCGGCCTGCGCATCGCGCCGGGCGTCGATTTCACGATCGT
CAATACCGAGCACGACGAGCGCTATCGCGATTTCTGGCAAACCTATTATCAGCTGATGGTGCGCAAGGGCATGGGCCCGC
AGCTCGCCAAGCTCGAAATGCGGCGCCGCACGACGCTGATCGGCGCGATGCTGGTGAAGAAGGGCGAGGCCGACGGCATG
ATCTGCGGCACGATCAGCACGACCCACCGCCACCTGCACTTCATCGACCAGGTGATCGGCAAGCGCGAGGGCTGCAGCGT
CTACGCCGCGATGAACGGCCTGGTGCTGCCGGGCCGCCAGATCTTCATCGTCGACACGCACGTCAACGTCGATCCAACGC
CCGAGCAACTGGCCGAGATCACCATGATGGCGGCCGAGGAAGTGCGCCGCTTCGGCATCGAGCCGAAGGTCGCGCTGCTC
TCGCATTCGAACTTCGGCACCAGCAACGCGCCGACCGCGCAGAAGATGCGCGATACGCTCGCGCTGCTCAAGGAGCGCGC
GCCGGGTCTCGAGGTGGACGGCGAGATGCACGGCGACGTCGCGCTCGATCCGCTGCTGCGCAAGGAAATCCTGCCGGATT
CGACGCTCGAGGGCGAGGCGAACCTGCTGGTGCTGCCGAACATCGATGCCGCCAACATTGCTTACAACCTGCTCAAGACC
GCGGCCGGCAACAACATCGCGATCGGCCCGATCCTGCTCGGTGCCGCGCGGCCGGTGCATGTGCTGACCGAATCGGCCAC
GGTGCGCCGGATCGTCAACATGGCCGCGCTGCTCGTCGCCGACGTGAACGCGACGCGCTGA

Upstream 100 bases:

>100_bases
CATTCCGGCCGCGGCCGTCGCGGCCGGAACGAGAAATCTGGATAAGGATTGGCGCTACAATATGAGCCGAACAGGTATTC
TAATCCCGCCCCCTCGACTC

Downstream 100 bases:

>100_bases
GCGTGGGCGGCGAGCGCGGCGCCGCCTGCTCTTGCCGCCGGCCCATGTCGTGACGGCTCATGCTGCGTCCGGCGTGGTGC
TGGCCTGCCGGACCCGTACC

Product: malic enzyme

Products: NA

Alternate protein names: NADP-ME [H]

Number of amino acids: Translated: 766; Mature: 765

Protein sequence:

>766_residues
MSTKSSPKADLRAAALDYHEFPTPGKIAVQPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTSRSNLVGVVTNGT
AVLGLGNIGPLASKPVMEGKAALFKKFAGIDVFDIELNESDPHKLVEVIAALEPTFGGINLEDIKAPDCFIVERECRKRM
KIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKQVKLVASGAGAAALACLDLLVDIGLPLENIFVTDLAGVVYRGRAELMD
PDKERFARETDARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVAHEVRPDAILATGRTDYP
NQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYAIEDLSFGPEYLIPKPFDPRLIVKIAPA
VAKAAMEGGVATRPIEDMDAYVQHLQQFVYHSGNTMKPVFQAARSAPLEKKRVVFAEGEEERVLRAVQILVDEHVAKPIL
IGRPHVIENRIKRFGLRIAPGVDFTIVNTEHDERYRDFWQTYYQLMVRKGMGPQLAKLEMRRRTTLIGAMLVKKGEADGM
ICGTISTTHRHLHFIDQVIGKREGCSVYAAMNGLVLPGRQIFIVDTHVNVDPTPEQLAEITMMAAEEVRRFGIEPKVALL
SHSNFGTSNAPTAQKMRDTLALLKERAPGLEVDGEMHGDVALDPLLRKEILPDSTLEGEANLLVLPNIDAANIAYNLLKT
AAGNNIAIGPILLGAARPVHVLTESATVRRIVNMAALLVADVNATR

Sequences:

>Translated_766_residues
MSTKSSPKADLRAAALDYHEFPTPGKIAVQPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTSRSNLVGVVTNGT
AVLGLGNIGPLASKPVMEGKAALFKKFAGIDVFDIELNESDPHKLVEVIAALEPTFGGINLEDIKAPDCFIVERECRKRM
KIPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKQVKLVASGAGAAALACLDLLVDIGLPLENIFVTDLAGVVYRGRAELMD
PDKERFARETDARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVAHEVRPDAILATGRTDYP
NQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYAIEDLSFGPEYLIPKPFDPRLIVKIAPA
VAKAAMEGGVATRPIEDMDAYVQHLQQFVYHSGNTMKPVFQAARSAPLEKKRVVFAEGEEERVLRAVQILVDEHVAKPIL
IGRPHVIENRIKRFGLRIAPGVDFTIVNTEHDERYRDFWQTYYQLMVRKGMGPQLAKLEMRRRTTLIGAMLVKKGEADGM
ICGTISTTHRHLHFIDQVIGKREGCSVYAAMNGLVLPGRQIFIVDTHVNVDPTPEQLAEITMMAAEEVRRFGIEPKVALL
SHSNFGTSNAPTAQKMRDTLALLKERAPGLEVDGEMHGDVALDPLLRKEILPDSTLEGEANLLVLPNIDAANIAYNLLKT
AAGNNIAIGPILLGAARPVHVLTESATVRRIVNMAALLVADVNATR
>Mature_765_residues
STKSSPKADLRAAALDYHEFPTPGKIAVQPTKQMINQRDLALAYSPGVAFACEEIVENPLNAARFTSRSNLVGVVTNGTA
VLGLGNIGPLASKPVMEGKAALFKKFAGIDVFDIELNESDPHKLVEVIAALEPTFGGINLEDIKAPDCFIVERECRKRMK
IPVFHDDQHGTAIVVAAAVTNGLKVVGKDIKQVKLVASGAGAAALACLDLLVDIGLPLENIFVTDLAGVVYRGRAELMDP
DKERFARETDARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILPEVAHEVRPDAILATGRTDYPN
QVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELAQQEQSDIVATAYAIEDLSFGPEYLIPKPFDPRLIVKIAPAV
AKAAMEGGVATRPIEDMDAYVQHLQQFVYHSGNTMKPVFQAARSAPLEKKRVVFAEGEEERVLRAVQILVDEHVAKPILI
GRPHVIENRIKRFGLRIAPGVDFTIVNTEHDERYRDFWQTYYQLMVRKGMGPQLAKLEMRRRTTLIGAMLVKKGEADGMI
CGTISTTHRHLHFIDQVIGKREGCSVYAAMNGLVLPGRQIFIVDTHVNVDPTPEQLAEITMMAAEEVRRFGIEPKVALLS
HSNFGTSNAPTAQKMRDTLALLKERAPGLEVDGEMHGDVALDPLLRKEILPDSTLEGEANLLVLPNIDAANIAYNLLKTA
AGNNIAIGPILLGAARPVHVLTESATVRRIVNMAALLVADVNATR

Specific function: Unknown

COG id: COG0281

COG function: function code C; Malic enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Homo sapiens, GI4505143, Length=343, Percent_Identity=27.4052478134111, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI62420882, Length=352, Percent_Identity=28.6931818181818, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI62420880, Length=352, Percent_Identity=28.6931818181818, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI239049447, Length=352, Percent_Identity=28.6931818181818, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4505145, Length=352, Percent_Identity=26.4204545454545, Blast_Score=71, Evalue=5e-12,
Organism=Homo sapiens, GI270265879, Length=318, Percent_Identity=27.6729559748428, Blast_Score=70, Evalue=9e-12,
Organism=Escherichia coli, GI1788806, Length=752, Percent_Identity=62.8989361702128, Blast_Score=970, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=316, Percent_Identity=32.2784810126582, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788635, Length=340, Percent_Identity=30.5882352941176, Blast_Score=147, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17537199, Length=466, Percent_Identity=24.8927038626609, Blast_Score=80, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322823, Length=239, Percent_Identity=30.5439330543933, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281362672, Length=473, Percent_Identity=27.6955602536998, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281362674, Length=473, Percent_Identity=27.6955602536998, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356279, Length=473, Percent_Identity=27.6955602536998, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI78707242, Length=410, Percent_Identity=25.8536585365854, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78707238, Length=410, Percent_Identity=25.8536585365854, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646388, Length=370, Percent_Identity=28.9189189189189, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI78707240, Length=349, Percent_Identity=26.0744985673352, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646386, Length=370, Percent_Identity=28.9189189189189, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015884
- InterPro:   IPR012301
- InterPro:   IPR012302
- InterPro:   IPR012188
- InterPro:   IPR016040
- InterPro:   IPR002505 [H]

Pfam domain/function: PF00390 malic; PF03949 Malic_M; PF01515 PTA_PTB [H]

EC number: =1.1.1.40 [H]

Molecular weight: Translated: 83220; Mature: 83089

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKSSPKADLRAAALDYHEFPTPGKIAVQPTKQMINQRDLALAYSPGVAFACEEIVENP
CCCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEECCCHHHHHHHHHHCC
LNAARFTSRSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAALFKKFAGIDVFDIELNES
CHHHHHCCCCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
DPHKLVEVIAALEPTFGGINLEDIKAPDCFIVERECRKRMKIPVFHDDQHGTAIVVAAAV
CHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHCCCCCEEECCCCCCEEEEEEHH
TNGLKVVGKDIKQVKLVASGAGAAALACLDLLVDIGLPLENIFVTDLAGVVYRGRAELMD
HCCHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCC
PDKERFARETDARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILP
CCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
EVAHEVRPDAILATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELA
HHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QQEQSDIVATAYAIEDLSFGPEYLIPKPFDPRLIVKIAPAVAKAAMEGGVATRPIEDMDA
HHHHCCCEEHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHH
YVQHLQQFVYHSGNTMKPVFQAARSAPLEKKRVVFAEGEEERVLRAVQILVDEHVAKPIL
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEE
IGRPHVIENRIKRFGLRIAPGVDFTIVNTEHDERYRDFWQTYYQLMVRKGMGPQLAKLEM
ECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRRTTLIGAMLVKKGEADGMICGTISTTHRHLHFIDQVIGKREGCSVYAAMNGLVLPGRQ
HHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCE
IFIVDTHVNVDPTPEQLAEITMMAAEEVRRFGIEPKVALLSHSNFGTSNAPTAQKMRDTL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
ALLKERAPGLEVDGEMHGDVALDPLLRKEILPDSTLEGEANLLVLPNIDAANIAYNLLKT
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AAGNNIAIGPILLGAARPVHVLTESATVRRIVNMAALLVADVNATR
CCCCCEEEHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STKSSPKADLRAAALDYHEFPTPGKIAVQPTKQMINQRDLALAYSPGVAFACEEIVENP
CCCCCCCHHHHHHHHHHHCCCCCCCEEECCHHHHCCCCCEEEEECCCHHHHHHHHHHCC
LNAARFTSRSNLVGVVTNGTAVLGLGNIGPLASKPVMEGKAALFKKFAGIDVFDIELNES
CHHHHHCCCCCEEEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
DPHKLVEVIAALEPTFGGINLEDIKAPDCFIVERECRKRMKIPVFHDDQHGTAIVVAAAV
CHHHHHHHHHHHCCCCCCCCHHHCCCCCEEEEEHHHHHCCCCCEEECCCCCCEEEEEEHH
TNGLKVVGKDIKQVKLVASGAGAAALACLDLLVDIGLPLENIFVTDLAGVVYRGRAELMD
HCCHHHHHCCHHHEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHCCC
PDKERFARETDARTLAEVIEGADIFLGLSAAGVLKQEMVKGMAERPLILALANPTPEILP
CCHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHH
EVAHEVRPDAILATGRTDYPNQVNNVLCFPFIFRGALDVGATTITREMEIAAVNAIAELA
HHHHHCCCCEEEECCCCCCCHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
QQEQSDIVATAYAIEDLSFGPEYLIPKPFDPRLIVKIAPAVAKAAMEGGVATRPIEDMDA
HHHHCCCEEHHHHHHHCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHCCCCCCCHHHHHH
YVQHLQQFVYHSGNTMKPVFQAARSAPLEKKRVVFAEGEEERVLRAVQILVDEHVAKPIL
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEE
IGRPHVIENRIKRFGLRIAPGVDFTIVNTEHDERYRDFWQTYYQLMVRKGMGPQLAKLEM
ECCCHHHHHHHHHCCCEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRRTTLIGAMLVKKGEADGMICGTISTTHRHLHFIDQVIGKREGCSVYAAMNGLVLPGRQ
HHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCE
IFIVDTHVNVDPTPEQLAEITMMAAEEVRRFGIEPKVALLSHSNFGTSNAPTAQKMRDTL
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHH
ALLKERAPGLEVDGEMHGDVALDPLLRKEILPDSTLEGEANLLVLPNIDAANIAYNLLKT
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
AAGNNIAIGPILLGAARPVHVLTESATVRRIVNMAALLVADVNATR
CCCCCEEEHHEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 36376 [H]