Click here to switch to the map view.

The map label for this gene is nrdB [H]

Identifier: 238026167

GI number: 238026167

Start: 526817

End: 528040

Strand: Direct

Name: nrdB [H]

Synonym: bglu_1g04970

Alternate gene names: 238026167

Gene position: 526817-528040 (Clockwise)

Preceding gene: 238026166

Following gene: 238026168

Centisome position: 13.49

GC content: 61.68

Gene sequence:

>1224_bases
ATGCTCAATTGGGATGACGAGAAGACGGCCGTAACTCCCGCGAGCGGAGCGCAGCACAACGCGATGCGCGCTCCCGCAGG
AATGGCTGTCGGAGTGCAGGCCGCGACGCCTGCCGCTCATCAGGCTCCGTCGGCGCGCGACATTTTCGAAGGTGACCTCG
CGGTCGCGCCGCATGCTTCGGCGGCGGCCGCCGTCGCCGGCGCGCAGGAACGGGTCAATATCGCCGACAAGCGCATCATC
AACGGCAAGACCGATGTCAATCAGTTGGTGCCGTTCAAGTACAAGTGGGCGTGGGAAAAGTATCTGGCCGGTTGCGCGAA
CCACTGGATGCCGCAGGAAATCAACATGTCCCGCGACATCGCGCTGTGGAAGGACCCGAACGGGCTGACCGAGGACGAGC
GCCGCATCGTCAGGCGCAATCTGGGTTTCTTCGTCACCGCCGACTCGCTCGCCGCGAACAACATCGTACTGGGCACCTAC
CGCCACATCACGGCGCCCGAGTGCCGGCAGTTCCTGCTGCGCCAGGCGTTCGAGGAAGCGATCCACACCCACGCCTACCA
GTACATCGTCGAATCGCTGGGCCTCGATGAGGGCGAGATCTTCAACGCCTATCACGAGGTCAGCTCGATTCGCGACAAGG
ACGAATTCCTGATCCCCTTCATCCATACGCTGACCGATCCGGCGTTCGTGACGGGTACCCAGGACGCGGACCAGAAGCTG
CTGAAGTCGCTGATCGTATTCGCCTGCATCATGGAAGGCCTGTTCTTCTATGTCGGCTTCACGCAGATTCTCGCGCTCGG
CCGCCAGAACAAGATGACGGGCGCCGCGGAGCAATACCAGTACATCCTGCGCGACGAGTCGATGCACTGCAATTTCGGCA
TCGACCTGATCAATCAGATCAAGCTCGAGAATCCGCATCTCTGGACGCCGGAGTTCCGCGCCGAGATCCGCGAACTGTTC
AAGCGTGCCGTCGAGCTCGAGTATCGCTATGCTGAAGACACGATGCCGCGCGGCGTGCTGGGCCTGAACGCCGCGATGTT
CAAGAGCTATCTGCGTTTCATCGCGAACCGCCGCTGCCAGCAGATCGGTCTCGACCCGCTGTACCCGAACGAGGAAAACC
CGTTCCCGTGGATGAGCGAGATGATCGACCTGAAGAAGGAGCGGAACTTCTTCGAGACGCGGGTGATCGAGTATCAGACG
GGCGGCGCGCTGTCCTGGGAGTAA

Upstream 100 bases:

>100_bases
AGGTCGCAACGCGAATCGAAAAAAGGAATTTTCGTGAGCGAACCCTTTTATCGCTCATGAAAAGATGGTACAAACCGTTC
TAAATTGATGGTGAGAATTT

Downstream 100 bases:

>100_bases
CCGGGCGCGACACCGAGGTAAGGATGAGAGCGCCGGGCGAGAGCCCGGCCCAAGGTTTAGGAGCAAGAACGCCTGATGCA
AAGGATGGCCTGCGCCGACA

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLNWDDEKTAVTPASGAQHNAMRAPAGMAVGVQAATPAAHQAPSARDIFEGDLAVAPHASAAAAVAGAQERVNIADKRII
NGKTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVRRNLGFFVTADSLAANNIVLGTY
RHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRDKDEFLIPFIHTLTDPAFVTGTQDADQKL
LKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTPEFRAEIRELF
KRAVELEYRYAEDTMPRGVLGLNAAMFKSYLRFIANRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQT
GGALSWE

Sequences:

>Translated_407_residues
MLNWDDEKTAVTPASGAQHNAMRAPAGMAVGVQAATPAAHQAPSARDIFEGDLAVAPHASAAAAVAGAQERVNIADKRII
NGKTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVRRNLGFFVTADSLAANNIVLGTY
RHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRDKDEFLIPFIHTLTDPAFVTGTQDADQKL
LKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTPEFRAEIRELF
KRAVELEYRYAEDTMPRGVLGLNAAMFKSYLRFIANRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQT
GGALSWE
>Mature_407_residues
MLNWDDEKTAVTPASGAQHNAMRAPAGMAVGVQAATPAAHQAPSARDIFEGDLAVAPHASAAAAVAGAQERVNIADKRII
NGKTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVRRNLGFFVTADSLAANNIVLGTY
RHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVSSIRDKDEFLIPFIHTLTDPAFVTGTQDADQKL
LKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTPEFRAEIRELF
KRAVELEYRYAEDTMPRGVLGLNAAMFKSYLRFIANRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQT
GGALSWE

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI4557845, Length=407, Percent_Identity=25.5528255528256, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI260064013, Length=407, Percent_Identity=25.5528255528256, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI289177074, Length=320, Percent_Identity=27.5, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI42544136, Length=320, Percent_Identity=27.5, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI289177076, Length=296, Percent_Identity=27.7027027027027, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1788567, Length=293, Percent_Identity=24.9146757679181, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17551968, Length=319, Percent_Identity=28.2131661442006, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI193206379, Length=304, Percent_Identity=23.3552631578947, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17567153, Length=224, Percent_Identity=25.8928571428571, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322434, Length=330, Percent_Identity=32.4242424242424, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321619, Length=320, Percent_Identity=23.75, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18079279, Length=320, Percent_Identity=28.125, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 46275; Mature: 46275

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNWDDEKTAVTPASGAQHNAMRAPAGMAVGVQAATPAAHQAPSARDIFEGDLAVAPHAS
CCCCCCCCCEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCCCHHHCCCCEECCCCH
AAAAVAGAQERVNIADKRIINGKTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDI
HHHHHHCHHHHHHHHHHHEECCCCCHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCE
ALWKDPNGLTEDERRIVRRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEA
EEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
IHTHAYQYIVESLGLDEGEIFNAYHEVSSIRDKDEFLIPFIHTLTDPAFVTGTQDADQKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCHHHHHH
LKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHE
KLENPHLWTPEFRAEIRELFKRAVELEYRYAEDTMPRGVLGLNAAMFKSYLRFIANRRCQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC
>Mature Secondary Structure
MLNWDDEKTAVTPASGAQHNAMRAPAGMAVGVQAATPAAHQAPSARDIFEGDLAVAPHAS
CCCCCCCCCEECCCCCCCCCCCCCCCCCEEECCCCCCHHHCCCCCCHHHCCCCEECCCCH
AAAAVAGAQERVNIADKRIINGKTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDI
HHHHHHCHHHHHHHHHHHEECCCCCHHHCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCE
ALWKDPNGLTEDERRIVRRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEA
EEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHH
IHTHAYQYIVESLGLDEGEIFNAYHEVSSIRDKDEFLIPFIHTLTDPAFVTGTQDADQKL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEECCCHHHHHH
LKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHE
KLENPHLWTPEFRAEIRELFKRAVELEYRYAEDTMPRGVLGLNAAMFKSYLRFIANRRCQ
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]