Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 238025977

GI number: 238025977

Start: 319367

End: 319972

Strand: Direct

Name: aroK [H]

Synonym: bglu_1g03030

Alternate gene names: 238025977

Gene position: 319367-319972 (Clockwise)

Preceding gene: 238025976

Following gene: 238025978

Centisome position: 8.18

GC content: 62.71

Gene sequence:

>606_bases
TTGCCAGTAAGCTGCGCCACACCACCAGCCAGATTGAAACAGAGGAAGCCGTTGCAAGCGCGGGATCCATACGCAAGCGT
ATTTTTCGTCGGACTCATGGGGGCCGGTAAGACCACCGTGGGTCGGGCCGTCGCGCGCCGTCTCGACCGGCCCTTCTTCG
ATTCCGATCACGAAATCGAAGCACGTACCGGTACGCGGATCCCGGTCATTTTCGAACTCGAGGGCGAGACCGGTTTTCGC
GACCGCGAGGAAAAGATGATCCACGAGCTCACGCTGCGCGGCAATGTCGTGCTCGCGACCGGCGGCGGCGCCGTGATGCG
CCCAGCAAACCGCGACGCGCTGCGTTCGCGCGGCATCGTCATCTATCTGCGTGCGAACCCGCACGATCTCTGGCTGAGAA
CCCGCAAGGACAAAAATCGCCCGCTGCTGCAGACGGAAGATCCGAAGGCCCGGCTCGAAGCCTTGTACGAGGTGCGCGAT
CCGCTCTACCGCGAATGCGCGCACTTCGTGATCGAAACCGGCCGTCCGTCGGTCAACGGACTCGTCAACATGGTGCTGAT
GCAGCTCGAGCTGGCCGGCATCGTCGCCAAGCCGCTACAAGCATGA

Upstream 100 bases:

>100_bases
CGCGCAGAACGGTCCGCCGGCGGGCGGCCCCGGCTCGGGGGACGAGTCGGCGGCGGCCCGCTGACCGCCCGCGACGGGTG
CGCTCGACAAGGCAAGCGCT

Downstream 100 bases:

>100_bases
TTACCGTCAACGTCGACCTGGGCGACTGCGCCTACCCGATTCATATCGGCGACGGCCTGATCGGCCGCACCGAACTGTTT
GCCCCGCACATCAAGGGCGC

Product: Shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MPVSCATPPARLKQRKPLQARDPYASVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGTRIPVIFELEGETGFR
DREEKMIHELTLRGNVVLATGGGAVMRPANRDALRSRGIVIYLRANPHDLWLRTRKDKNRPLLQTEDPKARLEALYEVRD
PLYRECAHFVIETGRPSVNGLVNMVLMQLELAGIVAKPLQA

Sequences:

>Translated_201_residues
MPVSCATPPARLKQRKPLQARDPYASVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGTRIPVIFELEGETGFR
DREEKMIHELTLRGNVVLATGGGAVMRPANRDALRSRGIVIYLRANPHDLWLRTRKDKNRPLLQTEDPKARLEALYEVRD
PLYRECAHFVIETGRPSVNGLVNMVLMQLELAGIVAKPLQA
>Mature_200_residues
PVSCATPPARLKQRKPLQARDPYASVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIEARTGTRIPVIFELEGETGFRD
REEKMIHELTLRGNVVLATGGGAVMRPANRDALRSRGIVIYLRANPHDLWLRTRKDKNRPLLQTEDPKARLEALYEVRDP
LYRECAHFVIETGRPSVNGLVNMVLMQLELAGIVAKPLQA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=166, Percent_Identity=48.7951807228916, Blast_Score=159, Evalue=9e-41,
Organism=Escherichia coli, GI1786587, Length=155, Percent_Identity=36.7741935483871, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 22582; Mature: 22450

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS01128 SHIKIMATE_KINASE ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSCATPPARLKQRKPLQARDPYASVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIE
CCCCCCCCHHHHHHCCCCCCCCCHHHHHEEHHCCCCCHHHHHHHHHHHCCCCCCCCCEEE
ARTGTRIPVIFELEGETGFRDREEKMIHELTLRGNVVLATGGGAVMRPANRDALRSRGIV
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHCCEE
IYLRANPHDLWLRTRKDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNG
EEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LVNMVLMQLELAGIVAKPLQA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PVSCATPPARLKQRKPLQARDPYASVFFVGLMGAGKTTVGRAVARRLDRPFFDSDHEIE
CCCCCCCHHHHHHCCCCCCCCCHHHHHEEHHCCCCCHHHHHHHHHHHCCCCCCCCCEEE
ARTGTRIPVIFELEGETGFRDREEKMIHELTLRGNVVLATGGGAVMRPANRDALRSRGIV
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHCCEE
IYLRANPHDLWLRTRKDKNRPLLQTEDPKARLEALYEVRDPLYRECAHFVIETGRPSVNG
EEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LVNMVLMQLELAGIVAKPLQA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA