Click here to switch to the map view.

The map label for this gene is guaA [H]

Identifier: 238025847

GI number: 238025847

Start: 181611

End: 182309

Strand: Reverse

Name: guaA [H]

Synonym: bglu_1g01730

Alternate gene names: 238025847

Gene position: 182309-181611 (Counterclockwise)

Preceding gene: 238025851

Following gene: 238025845

Centisome position: 4.67

GC content: 69.81

Gene sequence:

>699_bases
ATGGGTAAACGCTGCAACTGGGTCCGCACGGAGGCCGACGCGCATTATCACGACACTGAATGGGGGCGCCCGTCGCGCGA
CGATCGCCATCTGTTCGAAATGCTGATCCTCGAAGGCGCGCAGGCCGGCCTGTCGTGGTCGACGATTCTGAACAAGCGCG
AGAACTATCGCGCCGCGTTCGCGAACTTCGACGCCGACGCGGTGGCCCGCTTCACGCCGGCCCAGGTCGAGGCGCTGATG
CAGAACCCGGGCATCGTGCGCAACCGCCTGAAGATCGAATCGGCGATCGCCAATGCGCGCGCGGTCCAGCGCATCCGCGC
GGAGCACGGCTCGCTCGCCGTGTTCCTGTGGTCGTTCGTCGGCGACACGCCGGTGCAGAACGGCTGGCATTCGTATCGCG
ACGCGCCGGCCTCGACCGAGGCGTCCGACGCGCTCAGCAAGGCGCTCAAGCGCTACGGCTGCAAATTCGTCGGCTCGACG
ATCTGCTACGCGCTGATGCAGGCGATCGGGATGGTCAACGACCACGAATTCGACTGCCCCTGCCGGGCCGCCTGCGCGGC
GCTCGGCAAGCCGGCCGCCACGGCGGCCAGGGGCGCGGCCAGCCCGGCGGCCGGGGCGGCAAACACAACAAGAACGGCCA
GCCGGCCCGGCGCCGAGCGGCCCGCCGCGAAGCCGAAGAGGACCGCCTCCGCGGCCTGA

Upstream 100 bases:

>100_bases
ATCGCCGAATGGCCGGCTTGCGCGGCCTGGCCGTTCGGCTATGCTGGGCAGCGCCAGATCCGCGGGCCGACAATCGGGCC
GCCAACGACGCGAGGAATCG

Downstream 100 bases:

>100_bases
ATTCATACCGCGCCCCGGTCCCGGGCGCGCTGGAGCCGGAAAGCAAAACGGCGGTGCCGCCTCTTGCGAGGTGGCACCGC
CGTCGCGATGCGAACTGCGG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MGKRCNWVRTEADAHYHDTEWGRPSRDDRHLFEMLILEGAQAGLSWSTILNKRENYRAAFANFDADAVARFTPAQVEALM
QNPGIVRNRLKIESAIANARAVQRIRAEHGSLAVFLWSFVGDTPVQNGWHSYRDAPASTEASDALSKALKRYGCKFVGST
ICYALMQAIGMVNDHEFDCPCRAACAALGKPAATAARGAASPAAGAANTTRTASRPGAERPAAKPKRTASAA

Sequences:

>Translated_232_residues
MGKRCNWVRTEADAHYHDTEWGRPSRDDRHLFEMLILEGAQAGLSWSTILNKRENYRAAFANFDADAVARFTPAQVEALM
QNPGIVRNRLKIESAIANARAVQRIRAEHGSLAVFLWSFVGDTPVQNGWHSYRDAPASTEASDALSKALKRYGCKFVGST
ICYALMQAIGMVNDHEFDCPCRAACAALGKPAATAARGAASPAAGAANTTRTASRPGAERPAAKPKRTASAA
>Mature_231_residues
GKRCNWVRTEADAHYHDTEWGRPSRDDRHLFEMLILEGAQAGLSWSTILNKRENYRAAFANFDADAVARFTPAQVEALMQ
NPGIVRNRLKIESAIANARAVQRIRAEHGSLAVFLWSFVGDTPVQNGWHSYRDAPASTEASDALSKALKRYGCKFVGSTI
CYALMQAIGMVNDHEFDCPCRAACAALGKPAATAARGAASPAAGAANTTRTASRPGAERPAAKPKRTASAA

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=51.1111111111111, Blast_Score=184, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 25063; Mature: 24932

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRCNWVRTEADAHYHDTEWGRPSRDDRHLFEMLILEGAQAGLSWSTILNKRENYRAAF
CCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ANFDADAVARFTPAQVEALMQNPGIVRNRLKIESAIANARAVQRIRAEHGSLAVFLWSFV
HCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GDTPVQNGWHSYRDAPASTEASDALSKALKRYGCKFVGSTICYALMQAIGMVNDHEFDCP
CCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
CRAACAALGKPAATAARGAASPAAGAANTTRTASRPGAERPAAKPKRTASAA
HHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GKRCNWVRTEADAHYHDTEWGRPSRDDRHLFEMLILEGAQAGLSWSTILNKRENYRAAF
CCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ANFDADAVARFTPAQVEALMQNPGIVRNRLKIESAIANARAVQRIRAEHGSLAVFLWSFV
HCCCHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GDTPVQNGWHSYRDAPASTEASDALSKALKRYGCKFVGSTICYALMQAIGMVNDHEFDCP
CCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
CRAACAALGKPAATAARGAASPAAGAANTTRTASRPGAERPAAKPKRTASAA
HHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]