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The map label for this gene is rhtB [H]

Identifier: 238025834

GI number: 238025834

Start: 167700

End: 168326

Strand: Reverse

Name: rhtB [H]

Synonym: bglu_1g01600

Alternate gene names: 238025834

Gene position: 168326-167700 (Counterclockwise)

Preceding gene: 238025835

Following gene: 238025831

Centisome position: 4.31

GC content: 70.02

Gene sequence:

>627_bases
ATGACCTTCGAAACCTGGCTCGCGTTCGCCAGTGCGTGCATCGTGCTGGTACTGATCCCCGGCCCGACCATCCTGCTCGT
GATCGGCGATTCGCTGGCGAACCGTCACGGCTCGTCGTGGAGCACCGTGGCCGGCGTGGCGGCCGGCGACACCATCGCGA
TGGCCGTCTCGCTGGCCGGCGCGGGCGCGCTGCTCGCGCTGTCGGCCACCGCGTTCACGGCGCTCAAGCTGGCGGGCGGC
GCCTATCTGATCTATCTTGGCCTGCGCTCGATCCTGCAGGCGCGGGCAGCCGGCCGGCAGACCGTGCCGGCCGAGCCGAA
ATCGGCCGCGCGCCGCTTCCTGAGCGCATGGGCCGTCACCGCGCTGAACCCGAAGAGCATCGTGTTCTTCGTTGCGTTCG
TGCCGCAGTTCGTATCGCCTCACACCAGCTTCCTGTCGCAGTGCGCAGTGCTGGTGCCCACCTTCGTCTGCATCGCGACG
CTAAACGCCGCCTGCTACGCGCGCCTCGCACGCTACGCAGCCTCGCGGCTGACAGGCGCCACGGCACACCGCCGCTTCGC
CTGTGGCGGCGGCGCCTTGCTGATCGGCGCCGGCGTGCTGACGCTGCGGATGTCGTCCCGGCATTGA

Upstream 100 bases:

>100_bases
CCCGCCCCGGCGGTCGGTCAATCCTCCGCACCCGGTTCCGCTTGACAACGGGTAGCCGGCCGTGGATCACTGGTGGCTCA
TCACCGTCACGGAGCTTCCG

Downstream 100 bases:

>100_bases
GACATTGACGGCAACGGCGGGACGCGCGAGGCCTGTCGCGCGAACGGCACCATGGCGGGCCGATGCGACGCGCGCCACCC
GCCGCATGTACAAACGGGCA

Product: LysE family translocator protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTFETWLAFASACIVLVLIPGPTILLVIGDSLANRHGSSWSTVAGVAAGDTIAMAVSLAGAGALLALSATAFTALKLAGG
AYLIYLGLRSILQARAAGRQTVPAEPKSAARRFLSAWAVTALNPKSIVFFVAFVPQFVSPHTSFLSQCAVLVPTFVCIAT
LNAACYARLARYAASRLTGATAHRRFACGGGALLIGAGVLTLRMSSRH

Sequences:

>Translated_208_residues
MTFETWLAFASACIVLVLIPGPTILLVIGDSLANRHGSSWSTVAGVAAGDTIAMAVSLAGAGALLALSATAFTALKLAGG
AYLIYLGLRSILQARAAGRQTVPAEPKSAARRFLSAWAVTALNPKSIVFFVAFVPQFVSPHTSFLSQCAVLVPTFVCIAT
LNAACYARLARYAASRLTGATAHRRFACGGGALLIGAGVLTLRMSSRH
>Mature_207_residues
TFETWLAFASACIVLVLIPGPTILLVIGDSLANRHGSSWSTVAGVAAGDTIAMAVSLAGAGALLALSATAFTALKLAGGA
YLIYLGLRSILQARAAGRQTVPAEPKSAARRFLSAWAVTALNPKSIVFFVAFVPQFVSPHTSFLSQCAVLVPTFVCIATL
NAACYARLARYAASRLTGATAHRRFACGGGALLIGAGVLTLRMSSRH

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=210, Percent_Identity=34.2857142857143, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788099, Length=162, Percent_Identity=30.8641975308642, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21495; Mature: 21364

Theoretical pI: Translated: 11.07; Mature: 11.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFETWLAFASACIVLVLIPGPTILLVIGDSLANRHGSSWSTVAGVAAGDTIAMAVSLAG
CCHHHHHHHHHHHHEEEECCCCEEEEEECCHHHCCCCCCCHHHHHHCCCCHHHHHHHHCC
AGALLALSATAFTALKLAGGAYLIYLGLRSILQARAAGRQTVPAEPKSAARRFLSAWAVT
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALNPKSIVFFVAFVPQFVSPHTSFLSQCAVLVPTFVCIATLNAACYARLARYAASRLTGA
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TAHRRFACGGGALLIGAGVLTLRMSSRH
HHHCEEECCCCHHHHHHHEEEEEECCCC
>Mature Secondary Structure 
TFETWLAFASACIVLVLIPGPTILLVIGDSLANRHGSSWSTVAGVAAGDTIAMAVSLAG
CHHHHHHHHHHHHEEEECCCCEEEEEECCHHHCCCCCCCHHHHHHCCCCHHHHHHHHCC
AGALLALSATAFTALKLAGGAYLIYLGLRSILQARAAGRQTVPAEPKSAARRFLSAWAVT
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
ALNPKSIVFFVAFVPQFVSPHTSFLSQCAVLVPTFVCIATLNAACYARLARYAASRLTGA
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
TAHRRFACGGGALLIGAGVLTLRMSSRH
HHHCEEECCCCHHHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]