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The map label for this gene is epsD [H]

Identifier: 238025716

GI number: 238025716

Start: 36511

End: 38808

Strand: Reverse

Name: epsD [H]

Synonym: bglu_1g00380

Alternate gene names: 238025716

Gene position: 38808-36511 (Counterclockwise)

Preceding gene: 238025719

Following gene: 238025715

Centisome position: 0.99

GC content: 68.45

Gene sequence:

>2298_bases
ATGCGGCGCGCTGCCCAGGCTCTCGTCGTCGCCGGAATCGTCGCCTCGCAGGCCGCGCACGCCCAGGTCACGCTCAACTT
CGTCAATGCCGACATCGACCAGGTCGCGAAGGCGATCGGCGCCGCCACGGGCAAGACGATCATTGTCGATCCGCGCGTGA
AGGGCCAGCTCAACCTCGTCTCGGAGCACTCGGTGCCCGAGGAGCAGGCGCTCAAGACCCTGCAGTCGGCGCTGCGCATG
CAGGGCTTCTCGCTGCTGCAGGACCACGGCGTCCTCAAGGTGGTGCCGGAGGCCGACGCGAAGCTGCAGGGCGTGCCGAC
CTACGTCGGCAACACGCCGCGGGCCAATGGCGATCAGGTCGTCACGCAGGTGTTCGAGCTGCACAACGAATCGGCCAACA
ACCTGCTGCCGGTGCTGCGTCCGCTGATCTCCCCGAACAACACCGTGACGGCCTATCCGGCCAACAACACGCTGGTGGTG
ACCGATTACGCCGACAACATACGCCGCATCGCGCAGATCATCGCCGGCATCGACAACGCGGCCGGCACCCAGGTGGTGGT
GGTGCCGCTCAAGAACGCCAACGCGATCGACATCGCCAGCCAGCTCGGCAAGCTGCTCGACCCGGGCGCGATCGGCAATA
CCGACGCGACGCTGAAGGTCAACGTGAGCGCCGATCCGCGCACCAACTCGATCCTGCTGCGCGCCTCGAACGCCTCGCGC
CTCGCCTCCGCGCGGCGCCTGCTCGCGCAGCTCGACGCGCCGAGCGCCGCACCCGGCAACATGCATGTGATCCGGCTGCG
CAATGCCGATGCGGTGAAGCTGGCGAAGACCCTGCGCGGCATGATGGGCAAGGGCGACAGCGGCAGCTCGGCGTCCTCGA
ACGACGCCAATTCGTTCAACCAGGGCAATTCGAGCGGCAGCAGCTTCTCGACCGGCACCTCCGGCACCGCGCCGCTGCCG
TCCGGTTCGTCGTCGATGTCGTCGGGGTCGGGCAGCGGCGGCTACGGCAGCGGCAGCGGCAAGAACGACGGCTTCCTCGG
CGGCGACAAGGACAAGAGCGACGACAACCAGCCGGGCGGCATGATCCAGGCCGACGCGGCCACCAACTCGCTGATCATCA
CCGCGTCGGACCCGGTCTACCGGAACCTGCGCGCGGTGGTCGACCAGCTCGACGAGCGGCGCGCGCAGGTCTACATCGAG
GCGCTGATCGTCGAGCTGAACTCGAACACCTCGGCGAACCTCGGCATCCAGTGGCAGGTGGCCAACAACGCGCTCTACGC
CGGCAGCTCGCTCGGCACCAACGTCTCGGGCCTAGGCAACACGATCACCGGGCTGACCGCCGCGGCGGCCGCCGGCTCGG
CGGGCGGCGCCAACGGCGGGGCGGCCGCGGCGGCCTCGCTGACGCCGGGCCTGAACATCGGCTGGCTCAAGAACATGTTC
GGCATCACCGGCCTGGGCGCCCTGCTGCAGGCGTTCTCGGGCTCCAGCGACGCGAACGTGCTGTCCACGCCTAACCTCGT
CACGCTCGACAACGAGGAAGCGAAGATCGTGGTCGGCCAGAACGTGCCGATCGCCACCGGTTCGTATTCGAACCTGACGA
GCGGCAACTCGAGCAACGCGTTCAACACCTTCGACCGCCAGGACGTGGGCCTCACGCTGCACGTCAAGCCGCAGATCACC
GAAGGCGGGATCCTCAAGCTGCAGATCTACACCGAGGATTCGGCGGTGGTGCCGTCCACCACGTCCTCGACCGCGGTCGG
CGTGCCGACCTTCAGCAAGCGCTCGATCCAGTCGACCGTGCTTTGCGACAACGGCGAGATCATCGTGCTCGGCGGCCTGA
TGCAGGACAACTATCAGGTCGGCAACAACAAGGTGCCGCTGCTCGGCGATATTCCCTGGATCGGCCAGCTGTTCCGCTCC
GAAGGCAAGCAGCGCCAGAAGACCAACCTGATGGTGTTCCTGCGTCCGGTGATCCTGACCGACCACGCCACCACGCAGGC
CATCACCGCGAACCGCTACGACTACATCCAGGGCGTGCAGGGCGCATATCGCACCGACAACAACCTGATTCGCGACAAGG
ACGATCCGGTCACGCCGCCGATGCCGCTCGGCCCCGACGAAGGCGTCGCACCGGCCGCGAACCTGTTCGACCTGACGCGC
ATGACGCGCCGGCCCGGCTATCCGCCGGTGCCGGCCAGCGCCGGCGCGGCCACGCCGCCGGCCGCCAGCCAGCCCGCGCC
GGCCGTGACGACGCCGGTGCCCACGCCGGGCATCGCCTCGCCGGGAGCGCAGCCGTGA

Upstream 100 bases:

>100_bases
GTTAATGTCCGTTTTTTGCTCAATGTTGTTACGCTCCACCGTCGGATACGGCTACACCCCGGCATCGATCACCCACCTCA
TGACAACCATTCGTTTTGCT

Downstream 100 bases:

>100_bases
GCGAGCTCGCCAGCGCCGCGCCGGGCGAGCCGGCGGCCCCGTCCGCGGTGGCCGCGCGGCTGCTGCCGTACGGCTTCGCG
CGGGCCGGCCAGATCCTCGT

Product: general secretory pathway protein D

Products: NA

Alternate protein names: Cholera toxin secretion protein epsD [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MRRAAQALVVAGIVASQAAHAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLVSEHSVPEEQALKTLQSALRM
QGFSLLQDHGVLKVVPEADAKLQGVPTYVGNTPRANGDQVVTQVFELHNESANNLLPVLRPLISPNNTVTAYPANNTLVV
TDYADNIRRIAQIIAGIDNAAGTQVVVVPLKNANAIDIASQLGKLLDPGAIGNTDATLKVNVSADPRTNSILLRASNASR
LASARRLLAQLDAPSAAPGNMHVIRLRNADAVKLAKTLRGMMGKGDSGSSASSNDANSFNQGNSSGSSFSTGTSGTAPLP
SGSSSMSSGSGSGGYGSGSGKNDGFLGGDKDKSDDNQPGGMIQADAATNSLIITASDPVYRNLRAVVDQLDERRAQVYIE
ALIVELNSNTSANLGIQWQVANNALYAGSSLGTNVSGLGNTITGLTAAAAAGSAGGANGGAAAAASLTPGLNIGWLKNMF
GITGLGALLQAFSGSSDANVLSTPNLVTLDNEEAKIVVGQNVPIATGSYSNLTSGNSSNAFNTFDRQDVGLTLHVKPQIT
EGGILKLQIYTEDSAVVPSTTSSTAVGVPTFSKRSIQSTVLCDNGEIIVLGGLMQDNYQVGNNKVPLLGDIPWIGQLFRS
EGKQRQKTNLMVFLRPVILTDHATTQAITANRYDYIQGVQGAYRTDNNLIRDKDDPVTPPMPLGPDEGVAPAANLFDLTR
MTRRPGYPPVPASAGAATPPAASQPAPAVTTPVPTPGIASPGAQP

Sequences:

>Translated_765_residues
MRRAAQALVVAGIVASQAAHAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLVSEHSVPEEQALKTLQSALRM
QGFSLLQDHGVLKVVPEADAKLQGVPTYVGNTPRANGDQVVTQVFELHNESANNLLPVLRPLISPNNTVTAYPANNTLVV
TDYADNIRRIAQIIAGIDNAAGTQVVVVPLKNANAIDIASQLGKLLDPGAIGNTDATLKVNVSADPRTNSILLRASNASR
LASARRLLAQLDAPSAAPGNMHVIRLRNADAVKLAKTLRGMMGKGDSGSSASSNDANSFNQGNSSGSSFSTGTSGTAPLP
SGSSSMSSGSGSGGYGSGSGKNDGFLGGDKDKSDDNQPGGMIQADAATNSLIITASDPVYRNLRAVVDQLDERRAQVYIE
ALIVELNSNTSANLGIQWQVANNALYAGSSLGTNVSGLGNTITGLTAAAAAGSAGGANGGAAAAASLTPGLNIGWLKNMF
GITGLGALLQAFSGSSDANVLSTPNLVTLDNEEAKIVVGQNVPIATGSYSNLTSGNSSNAFNTFDRQDVGLTLHVKPQIT
EGGILKLQIYTEDSAVVPSTTSSTAVGVPTFSKRSIQSTVLCDNGEIIVLGGLMQDNYQVGNNKVPLLGDIPWIGQLFRS
EGKQRQKTNLMVFLRPVILTDHATTQAITANRYDYIQGVQGAYRTDNNLIRDKDDPVTPPMPLGPDEGVAPAANLFDLTR
MTRRPGYPPVPASAGAATPPAASQPAPAVTTPVPTPGIASPGAQP
>Mature_765_residues
MRRAAQALVVAGIVASQAAHAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLVSEHSVPEEQALKTLQSALRM
QGFSLLQDHGVLKVVPEADAKLQGVPTYVGNTPRANGDQVVTQVFELHNESANNLLPVLRPLISPNNTVTAYPANNTLVV
TDYADNIRRIAQIIAGIDNAAGTQVVVVPLKNANAIDIASQLGKLLDPGAIGNTDATLKVNVSADPRTNSILLRASNASR
LASARRLLAQLDAPSAAPGNMHVIRLRNADAVKLAKTLRGMMGKGDSGSSASSNDANSFNQGNSSGSSFSTGTSGTAPLP
SGSSSMSSGSGSGGYGSGSGKNDGFLGGDKDKSDDNQPGGMIQADAATNSLIITASDPVYRNLRAVVDQLDERRAQVYIE
ALIVELNSNTSANLGIQWQVANNALYAGSSLGTNVSGLGNTITGLTAAAAAGSAGGANGGAAAAASLTPGLNIGWLKNMF
GITGLGALLQAFSGSSDANVLSTPNLVTLDNEEAKIVVGQNVPIATGSYSNLTSGNSSNAFNTFDRQDVGLTLHVKPQIT
EGGILKLQIYTEDSAVVPSTTSSTAVGVPTFSKRSIQSTVLCDNGEIIVLGGLMQDNYQVGNNKVPLLGDIPWIGQLFRS
EGKQRQKTNLMVFLRPVILTDHATTQAITANRYDYIQGVQGAYRTDNNLIRDKDDPVTPPMPLGPDEGVAPAANLFDLTR
MTRRPGYPPVPASAGAATPPAASQPAPAVTTPVPTPGIASPGAQP

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=683, Percent_Identity=33.0893118594436, Blast_Score=290, Evalue=3e-79,
Organism=Escherichia coli, GI1789793, Length=302, Percent_Identity=28.1456953642384, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR013356
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 78908; Mature: 78908

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAAQALVVAGIVASQAAHAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLV
CCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCEEEEE
SEHSVPEEQALKTLQSALRMQGFSLLQDHGVLKVVPEADAKLQGVPTYVGNTPRANGDQV
ECCCCCHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHH
VTQVFELHNESANNLLPVLRPLISPNNTVTAYPANNTLVVTDYADNIRRIAQIIAGIDNA
HHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCC
AGTQVVVVPLKNANAIDIASQLGKLLDPGAIGNTDATLKVNVSADPRTNSILLRASNASR
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCHHH
LASARRLLAQLDAPSAAPGNMHVIRLRNADAVKLAKTLRGMMGKGDSGSSASSNDANSFN
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QGNSSGSSFSTGTSGTAPLPSGSSSMSSGSGSGGYGSGSGKNDGFLGGDKDKSDDNQPGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MIQADAATNSLIITASDPVYRNLRAVVDQLDERRAQVYIEALIVELNSNTSANLGIQWQV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCEEEEEEE
ANNALYAGSSLGTNVSGLGNTITGLTAAAAAGSAGGANGGAAAAASLTPGLNIGWLKNMF
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
GITGLGALLQAFSGSSDANVLSTPNLVTLDNEEAKIVVGQNVPIATGSYSNLTSGNSSNA
HHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCEEEEECCCCCEECCCCCCCCCCCCCCC
FNTFDRQDVGLTLHVKPQITEGGILKLQIYTEDSAVVPSTTSSTAVGVPTFSKRSIQSTV
CCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCEECCCCCCCCEECCCCCCCCCCCEEE
LCDNGEIIVLGGLMQDNYQVGNNKVPLLGDIPWIGQLFRSEGKQRQKTNLMVFLRPVILT
EECCCCEEEEECEECCCEEECCCCCCEEECCHHHHHHHHHCCHHHHHCCEEEEEEEEEEE
DHATTQAITANRYDYIQGVQGAYRTDNNLIRDKDDPVTPPMPLGPDEGVAPAANLFDLTR
CCCCHHEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
MTRRPGYPPVPASAGAATPPAASQPAPAVTTPVPTPGIASPGAQP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRAAQALVVAGIVASQAAHAQVTLNFVNADIDQVAKAIGAATGKTIIVDPRVKGQLNLV
CCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCCCEEEEE
SEHSVPEEQALKTLQSALRMQGFSLLQDHGVLKVVPEADAKLQGVPTYVGNTPRANGDQV
ECCCCCHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHH
VTQVFELHNESANNLLPVLRPLISPNNTVTAYPANNTLVVTDYADNIRRIAQIIAGIDNA
HHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCC
AGTQVVVVPLKNANAIDIASQLGKLLDPGAIGNTDATLKVNVSADPRTNSILLRASNASR
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCHHH
LASARRLLAQLDAPSAAPGNMHVIRLRNADAVKLAKTLRGMMGKGDSGSSASSNDANSFN
HHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QGNSSGSSFSTGTSGTAPLPSGSSSMSSGSGSGGYGSGSGKNDGFLGGDKDKSDDNQPGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MIQADAATNSLIITASDPVYRNLRAVVDQLDERRAQVYIEALIVELNSNTSANLGIQWQV
EEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCEEEEEEE
ANNALYAGSSLGTNVSGLGNTITGLTAAAAAGSAGGANGGAAAAASLTPGLNIGWLKNMF
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHHH
GITGLGALLQAFSGSSDANVLSTPNLVTLDNEEAKIVVGQNVPIATGSYSNLTSGNSSNA
HHHHHHHHHHHHCCCCCCCEECCCCEEEECCCCEEEEECCCCCEECCCCCCCCCCCCCCC
FNTFDRQDVGLTLHVKPQITEGGILKLQIYTEDSAVVPSTTSSTAVGVPTFSKRSIQSTV
CCCCCCCCCCEEEEECCCCCCCCEEEEEEEECCCEECCCCCCCCEECCCCCCCCCCCEEE
LCDNGEIIVLGGLMQDNYQVGNNKVPLLGDIPWIGQLFRSEGKQRQKTNLMVFLRPVILT
EECCCCEEEEECEECCCEEECCCCCCEEECCHHHHHHHHHCCHHHHHCCEEEEEEEEEEE
DHATTQAITANRYDYIQGVQGAYRTDNNLIRDKDDPVTPPMPLGPDEGVAPAANLFDLTR
CCCCHHEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
MTRRPGYPPVPASAGAATPPAASQPAPAVTTPVPTPGIASPGAQP
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]