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The map label for this gene is uvrY [H]

Identifier: 238025347

GI number: 238025347

Start: 2512426

End: 2513070

Strand: Direct

Name: uvrY [H]

Synonym: bglu_2g20230

Alternate gene names: 238025347

Gene position: 2512426-2513070 (Clockwise)

Preceding gene: 238025346

Following gene: 238025348

Centisome position: 88.86

GC content: 67.13

Gene sequence:

>645_bases
ATGATCGAGGTGCTTCTCGCGGACGACCACGCCATGGTGCGCGACGGCTTGCGCTACATCCTGCAGAACACCAGCGGCTT
CCAGGTGGCGGGCGAGGCGGCGGACGGCCCCGCCACGCTCGCGCTGGTGCGCGGCACCGGCGCGCAGCTGCTGGTGCTCG
ACCTCTCCATGCCGGGCGGCGGCGTCGAGCTGATCGGCAAGATCAGGCAGGAAGCGCCGGCGCTGCGCATCCTGGTGCTG
ACCATGCATGCCGAGCAGCAATACGCGGTGCGGGTGTTCCGCGCCGGCGCGTCGGGATACATGACCAAGGAAAGCGCCAG
CACCGAACTGGTCGATGCACTGGCCAGAATCGCCGCCGGCGGCGTCTATGTGAGCCTGGCGATGGCCGAGCGCCTTGCCC
AAAGCCTCAACGAACGTCTCGATACCCTGCCGGACCAGCGCCTGTCCGGTCGCGAAATCGACGTGTTCCGGCGCATCGCG
GCGGGCTGCACGGTGTGCGAGATCGCACATGCGCTCGGCCTGAGCGTCAAGACCGTGAGCACCTACAAGACGCGCATCCT
CGAAAAGATGAAGCTGCCACACGAGGCCGCGCTGGTGCGTTACGCCATCCGGCACAAGCTGTTCGACGATCAGCTCGACG
TCTGA

Upstream 100 bases:

>100_bases
CGCTCGGCGGCCGGCTGACGATCGCCGGCCCGCCGGGTCAGGGCTTTTCGATCACCGTCACGCTGCCGCTGGCCGTGGTG
CAGCAGGGAGCGCCAGGCTC

Downstream 100 bases:

>100_bases
CACGCGCGCCCCGCGCCGCCCGTGGCGCGTGGTGCCTGTGCGCCGCCCGCCGGTCCGGCCGGCTCCCTGCGGCGCCCGCC
TTTGACCCTGGTCAATCGTC

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MIEVLLADDHAMVRDGLRYILQNTSGFQVAGEAADGPATLALVRGTGAQLLVLDLSMPGGGVELIGKIRQEAPALRILVL
TMHAEQQYAVRVFRAGASGYMTKESASTELVDALARIAAGGVYVSLAMAERLAQSLNERLDTLPDQRLSGREIDVFRRIA
AGCTVCEIAHALGLSVKTVSTYKTRILEKMKLPHEAALVRYAIRHKLFDDQLDV

Sequences:

>Translated_214_residues
MIEVLLADDHAMVRDGLRYILQNTSGFQVAGEAADGPATLALVRGTGAQLLVLDLSMPGGGVELIGKIRQEAPALRILVL
TMHAEQQYAVRVFRAGASGYMTKESASTELVDALARIAAGGVYVSLAMAERLAQSLNERLDTLPDQRLSGREIDVFRRIA
AGCTVCEIAHALGLSVKTVSTYKTRILEKMKLPHEAALVRYAIRHKLFDDQLDV
>Mature_214_residues
MIEVLLADDHAMVRDGLRYILQNTSGFQVAGEAADGPATLALVRGTGAQLLVLDLSMPGGGVELIGKIRQEAPALRILVL
TMHAEQQYAVRVFRAGASGYMTKESASTELVDALARIAAGGVYVSLAMAERLAQSLNERLDTLPDQRLSGREIDVFRRIA
AGCTVCEIAHALGLSVKTVSTYKTRILEKMKLPHEAALVRYAIRHKLFDDQLDV

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop. Mediates the

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=211, Percent_Identity=37.4407582938389, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790102, Length=210, Percent_Identity=32.8571428571429, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=28.8461538461538, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788521, Length=196, Percent_Identity=30.6122448979592, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787473, Length=182, Percent_Identity=33.5164835164835, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788712, Length=210, Percent_Identity=25.2380952380952, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082052, Length=118, Percent_Identity=30.5084745762712, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23200; Mature: 23200

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEVLLADDHAMVRDGLRYILQNTSGFQVAGEAADGPATLALVRGTGAQLLVLDLSMPGG
CEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCC
GVELIGKIRQEAPALRILVLTMHAEQQYAVRVFRAGASGYMTKESASTELVDALARIAAG
HHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCC
GVYVSLAMAERLAQSLNERLDTLPDQRLSGREIDVFRRIAAGCTVCEIAHALGLSVKTVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
TYKTRILEKMKLPHEAALVRYAIRHKLFDDQLDV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEVLLADDHAMVRDGLRYILQNTSGFQVAGEAADGPATLALVRGTGAQLLVLDLSMPGG
CEEEEEECCHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEECCCCEEEEEEECCCCC
GVELIGKIRQEAPALRILVLTMHAEQQYAVRVFRAGASGYMTKESASTELVDALARIAAG
HHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHCC
GVYVSLAMAERLAQSLNERLDTLPDQRLSGREIDVFRRIAAGCTVCEIAHALGLSVKTVS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
TYKTRILEKMKLPHEAALVRYAIRHKLFDDQLDV
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]