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The map label for this gene is emrK [H]

Identifier: 238025330

GI number: 238025330

Start: 2492116

End: 2493351

Strand: Direct

Name: emrK [H]

Synonym: bglu_2g20040

Alternate gene names: 238025330

Gene position: 2492116-2493351 (Clockwise)

Preceding gene: 238025329

Following gene: 238025331

Centisome position: 88.14

GC content: 72.9

Gene sequence:

>1236_bases
ATGAACCGCACCGACAATCCGCAGGCTGCCGCGGGCGCGGCCGCACCCCCGCCCGCCGAACCCGCGCTGCCCGACAGGCG
CCGCCGCTACTTCCGCTGGTTCTTCATCGCGCTCGCCCTGGCCGCGCTGGCCGGCGGCTACTGGTGGATCGCCTCGCGCG
ACACCGAGACGACCGACGACGCCTACGTGACGGGGGACGTGGTACAGGTATCGCCGCAGGTCGCCGGCACGGTCGACGCG
ATCATGGTGCAGAACGCCGAATGGGTGCGTGCCGGCGATCCGCTGTTCCGCATCGATCCGACCGATGCGAGGCTCGCGCT
CGACGACGCCGTCGCACAGCTCGCCCGCGCGGTGCGCGAGTACCGCACCGCGCGGGCCGACACCGCCCGCGAGGCAGCAC
AGATCCTGCTGCGCAAGGCCGAACTGTCGAAGGCGTCCGACGACCTGCAGCGACGGCTCGGCCTGGCGCAGGACGGCGGC
GTATCGCGCGAGGACCTCCGCCACGCGCGCGACGCCATGGACAGCGCGTCCGCCGCGCTCGACGCGCAACAGGCCGCATA
CGACGCATCGCGCGCCCGCATCGACGGCACCTCGATCGACTCGAATCCGCTGGTGCGCGCCGCAGCCGCGCGCGTGCGCA
GTGCGGCCCTCGCGCTGCGCCGCACCGAGATTCGCGCGCCGCTGGCGGGTCTCGTGACACGCCGTGCCGTGCAGGTCGGG
CAGCACGTCGCGCCCGGCACGCCGGCCATGGCGCTGGTGCCGCTCGAGCATGTGTGGGTCGAGGCCAATTTCAAGGAATC
GCAGTTGCGCGGCATGCACGCCGGGCAGGCCGTGACGCTGCGCTCCGACCTGTATGGCGCGAGCGTCGTGTTCCACGGCC
GCATCGAAGGCGTCGAGGCCGGCACGGGTTCGGCGTTTGCCTCGGTGCCCGCGCAGAACGCGACCGGCAACTGGATCAAG
GTGGTGCAACGCGTACCGGTGCGAATCGCGCTCGACCCCGGCGAACTGCGCGCGCATCCGCTGCGCATCGGGCTGTCGAT
GAACGCATCGGTCGCGCTCGGCGACGGCGCGCCCGGCACCGCGTCGGCCTCCATGCAGACCACCTCGGCCGCTGCTCGGC
GCCCGGTCGACGCGACCTCGATCTTCGACGACGATGCCTCGTCCGGCGATGCGCTCGTCATCGACACGATTCGCGCGAAC
GACGGTGCGGCCGCCGCGCGCGCGCCGGGAGCCTGA

Upstream 100 bases:

>100_bases
AAGACCGCCGATCGGTCGCTCGCGCCGACACCTCACTTGCCGTCGAACACGTCCGGCTGATCGCCGCGCTCGGTGGCGCA
ACCAACCCAGGAGCCCAGCC

Downstream 100 bases:

>100_bases
CGATGGCGCACGTCACTCGGGGGGCGGCGCCGAAACTGCCGCTGGGGCCGATGCAAGGCCCGGCTCTCGTGCTCGTCGCG
ATCGCGATCAGCGTCGCCAA

Product: major facilitator superfamily efflux pump membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNRTDNPQAAAGAAAPPPAEPALPDRRRRYFRWFFIALALAALAGGYWWIASRDTETTDDAYVTGDVVQVSPQVAGTVDA
IMVQNAEWVRAGDPLFRIDPTDARLALDDAVAQLARAVREYRTARADTAREAAQILLRKAELSKASDDLQRRLGLAQDGG
VSREDLRHARDAMDSASAALDAQQAAYDASRARIDGTSIDSNPLVRAAAARVRSAALALRRTEIRAPLAGLVTRRAVQVG
QHVAPGTPAMALVPLEHVWVEANFKESQLRGMHAGQAVTLRSDLYGASVVFHGRIEGVEAGTGSAFASVPAQNATGNWIK
VVQRVPVRIALDPGELRAHPLRIGLSMNASVALGDGAPGTASASMQTTSAAARRPVDATSIFDDDASSGDALVIDTIRAN
DGAAAARAPGA

Sequences:

>Translated_411_residues
MNRTDNPQAAAGAAAPPPAEPALPDRRRRYFRWFFIALALAALAGGYWWIASRDTETTDDAYVTGDVVQVSPQVAGTVDA
IMVQNAEWVRAGDPLFRIDPTDARLALDDAVAQLARAVREYRTARADTAREAAQILLRKAELSKASDDLQRRLGLAQDGG
VSREDLRHARDAMDSASAALDAQQAAYDASRARIDGTSIDSNPLVRAAAARVRSAALALRRTEIRAPLAGLVTRRAVQVG
QHVAPGTPAMALVPLEHVWVEANFKESQLRGMHAGQAVTLRSDLYGASVVFHGRIEGVEAGTGSAFASVPAQNATGNWIK
VVQRVPVRIALDPGELRAHPLRIGLSMNASVALGDGAPGTASASMQTTSAAARRPVDATSIFDDDASSGDALVIDTIRAN
DGAAAARAPGA
>Mature_411_residues
MNRTDNPQAAAGAAAPPPAEPALPDRRRRYFRWFFIALALAALAGGYWWIASRDTETTDDAYVTGDVVQVSPQVAGTVDA
IMVQNAEWVRAGDPLFRIDPTDARLALDDAVAQLARAVREYRTARADTAREAAQILLRKAELSKASDDLQRRLGLAQDGG
VSREDLRHARDAMDSASAALDAQQAAYDASRARIDGTSIDSNPLVRAAAARVRSAALALRRTEIRAPLAGLVTRRAVQVG
QHVAPGTPAMALVPLEHVWVEANFKESQLRGMHAGQAVTLRSDLYGASVVFHGRIEGVEAGTGSAFASVPAQNATGNWIK
VVQRVPVRIALDPGELRAHPLRIGLSMNASVALGDGAPGTASASMQTTSAAARRPVDATSIFDDDASSGDALVIDTIRAN
DGAAAARAPGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=372, Percent_Identity=42.2043010752688, Blast_Score=302, Evalue=3e-83,
Organism=Escherichia coli, GI1789041, Length=398, Percent_Identity=41.9597989949749, Blast_Score=300, Evalue=9e-83,
Organism=Escherichia coli, GI1790519, Length=308, Percent_Identity=30.1948051948052, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081951, Length=315, Percent_Identity=28.2539682539683, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789637, Length=313, Percent_Identity=26.517571884984, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790024, Length=283, Percent_Identity=25.4416961130742, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790012, Length=247, Percent_Identity=25.9109311740891, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789900, Length=254, Percent_Identity=27.9527559055118, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43356; Mature: 43356

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTDNPQAAAGAAAPPPAEPALPDRRRRYFRWFFIALALAALAGGYWWIASRDTETTDD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
AYVTGDVVQVSPQVAGTVDAIMVQNAEWVRAGDPLFRIDPTDARLALDDAVAQLARAVRE
CEEECCEEEECCCHHCCEEEEEECCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
YRTARADTAREAAQILLRKAELSKASDDLQRRLGLAQDGGVSREDLRHARDAMDSASAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
DAQQAAYDASRARIDGTSIDSNPLVRAAAARVRSAALALRRTEIRAPLAGLVTRRAVQVG
HHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
QHVAPGTPAMALVPLEHVWVEANFKESQLRGMHAGQAVTLRSDLYGASVVFHGRIEGVEA
CCCCCCCCCEEEEEHEEEEEECCCCHHHHCCCCCCCEEEEECCCCCCEEEEECEECCEEC
GTGSAFASVPAQNATGNWIKVVQRVPVRIALDPGELRAHPLRIGLSMNASVALGDGAPGT
CCCCCEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCC
ASASMQTTSAAARRPVDATSIFDDDASSGDALVIDTIRANDGAAAARAPGA
CCCCCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNRTDNPQAAAGAAAPPPAEPALPDRRRRYFRWFFIALALAALAGGYWWIASRDTETTDD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
AYVTGDVVQVSPQVAGTVDAIMVQNAEWVRAGDPLFRIDPTDARLALDDAVAQLARAVRE
CEEECCEEEECCCHHCCEEEEEECCCCEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHH
YRTARADTAREAAQILLRKAELSKASDDLQRRLGLAQDGGVSREDLRHARDAMDSASAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
DAQQAAYDASRARIDGTSIDSNPLVRAAAARVRSAALALRRTEIRAPLAGLVTRRAVQVG
HHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
QHVAPGTPAMALVPLEHVWVEANFKESQLRGMHAGQAVTLRSDLYGASVVFHGRIEGVEA
CCCCCCCCCEEEEEHEEEEEECCCCHHHHCCCCCCCEEEEECCCCCCEEEEECEECCEEC
GTGSAFASVPAQNATGNWIKVVQRVPVRIALDPGELRAHPLRIGLSMNASVALGDGAPGT
CCCCCEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCEEEEEEECCCEEEECCCCCCC
ASASMQTTSAAARRPVDATSIFDDDASSGDALVIDTIRANDGAAAARAPGA
CCCCCHHHHHHHHCCCCHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]