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The map label for this gene is aldH [H]

Identifier: 238025160

GI number: 238025160

Start: 2284045

End: 2285631

Strand: Direct

Name: aldH [H]

Synonym: bglu_2g18260

Alternate gene names: 238025160

Gene position: 2284045-2285631 (Clockwise)

Preceding gene: 238025158

Following gene: 238025162

Centisome position: 80.78

GC content: 73.72

Gene sequence:

>1587_bases
ATGACACACGAAATCACCGGAAACATGTTGCTGGGCGCGGCCTCGGTCCGCGGCACGCAGGGCGTGCTGCGCGCGTTCGC
GCCGGCCACCGGCACCGAACTCGAGCCGGAATTCGGCGCCGGCGGCCCGGCCGACGTCGATCGCGCCTGCCGCCTCGCGG
GCGAGGCGTTCGACGCCTTCCGCGCCGCGCCGCCGGACACGCGCGCGGCGCTGCTCGAGGCCATCGCCACCGGCATCGAG
CAGCTCGGCGCGACGCTGATCGAGCGCCTGCACCTGGAAACGGCGCTGCCGGTCGCGCGCCTCGAAGGCGAGCGCGCGCG
CACCTGCGGGCAGTTGCGCCTGTTCGCGCAACTGGTGCGCGACGGGCGCTGGAACGATGCCACGCTCGACTCGGCGCTGC
CCGAGCGCAAGCCGCTGCCGCGCGCCGACCTGCGCGCGCGCAAGATCCCGATCGGCCCGGTGGCGGTGTTCGGCGCCAGC
AACTTCCCGCTCGCGTTCTCGGTGGCGGGCGGCGACACGGCCTCCGCGCTCGCGGCCGGCTGCCCGGTGGTGGTGAAGGC
GCACGAGGCGCATCTGGGCGGCTCGGAGCTGGTGGGCCGCGCGATCCAGCAGGCGGTGGCCGAGCTCGGCCTGCCCGAGG
GCACGTTCTCCCTCGTGATCGGCAAGGGCAACGCGGTCGGCGAGGCGCTGGTGGCGCATCCGGCCATCAAGGCGGTCGGC
TTCACCGGCTCGCGCCGCGGCGGCCTCGCGCTGTCGGCGATCGCCGCCGCGCGCGCCGAGCCGATTCCGGTTCACGCCGA
AATGAGCAGCATCAACCCGGTGCTGGTGCTGCCGGCCGCGCTGAAGGCGCGCGGCGCGCAGCTCGCGCAGGGCTTCGTGG
ATTCGCTGGTGCTCGGCGCCGGCCAGTTCTGCACGAATCCGGGCCTGGTACTTGCGATCGAAGGCCCGGAACTCGACGCG
TTCGTGGCCGCCGCCTCGGCCGCGCTCGCCGGCAAGCCGTCGCAGGTCATGCTGACGGCCGGCATCGCCGCCACCTATCG
CCGCCAGATCGACGAGCGCGCGCAGCAGCCGGACGTGGCGCGCGTGGCCGACGGCGTCGCCTCCGACAACGCCTGCGGCG
CGCTGCCGGTGCTGTTCCGCGCCAAGGCGGCCGACTTCATGGCGAACCACGGCCTGGCCGAAGAGATCTTCGGGCCGGCC
TCGATCGTGGTGGCATGCCGCGACGAGCAGGAGCTGCTGGGCGTGCTGGACGGCATCGAGGGCCAGCTCACGGCCACGCT
GCTGCTGGATCCGGCCGACTACCCGGTCGCGAAGCGCGTGCTGCCGGTGCTCGAACGCAAGGTGGGCCGGATTCTCGCGA
ACGGCTATCCGACCGGCGTCGAGGTCTGCCACGCGATGGTTCACGGCGGCCCGTTCCCTGCCACCTCCGATTCGCGCACG
ACCTCGGTGGGCACCATGGCGATCGACCGCTTCCTGCGCCCGGTCTGCTACCAGGACCTGCCGGCCGAGCTGCTGCCCGA
GGCGCTGCAAGACGCGAACCCGCTCGGCATCTGGCGCCTGCGCGACGGCGAACTCGTGCGGCGCTGA

Upstream 100 bases:

>100_bases
CGGGGCCCATGCGTGCGTCATGCTTGCGAAAGCAATGCGTGAAGCACGATCCGCGCCGGCAGGCGCCACTCGATTCGCCG
ATTCGCAGGAGAGATATCGC

Downstream 100 bases:

>100_bases
GCGCCGCCGCCCGCTCGCGGGCGTATTGCTTGACCAAGGCCGGCGCGGTTTCGCGCCGGCCTTGGTGATTGGCGCGCCGG
CAGTTCGGTGCAAGGCGGCG

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MTHEITGNMLLGAASVRGTQGVLRAFAPATGTELEPEFGAGGPADVDRACRLAGEAFDAFRAAPPDTRAALLEAIATGIE
QLGATLIERLHLETALPVARLEGERARTCGQLRLFAQLVRDGRWNDATLDSALPERKPLPRADLRARKIPIGPVAVFGAS
NFPLAFSVAGGDTASALAAGCPVVVKAHEAHLGGSELVGRAIQQAVAELGLPEGTFSLVIGKGNAVGEALVAHPAIKAVG
FTGSRRGGLALSAIAAARAEPIPVHAEMSSINPVLVLPAALKARGAQLAQGFVDSLVLGAGQFCTNPGLVLAIEGPELDA
FVAAASAALAGKPSQVMLTAGIAATYRRQIDERAQQPDVARVADGVASDNACGALPVLFRAKAADFMANHGLAEEIFGPA
SIVVACRDEQELLGVLDGIEGQLTATLLLDPADYPVAKRVLPVLERKVGRILANGYPTGVEVCHAMVHGGPFPATSDSRT
TSVGTMAIDRFLRPVCYQDLPAELLPEALQDANPLGIWRLRDGELVRR

Sequences:

>Translated_528_residues
MTHEITGNMLLGAASVRGTQGVLRAFAPATGTELEPEFGAGGPADVDRACRLAGEAFDAFRAAPPDTRAALLEAIATGIE
QLGATLIERLHLETALPVARLEGERARTCGQLRLFAQLVRDGRWNDATLDSALPERKPLPRADLRARKIPIGPVAVFGAS
NFPLAFSVAGGDTASALAAGCPVVVKAHEAHLGGSELVGRAIQQAVAELGLPEGTFSLVIGKGNAVGEALVAHPAIKAVG
FTGSRRGGLALSAIAAARAEPIPVHAEMSSINPVLVLPAALKARGAQLAQGFVDSLVLGAGQFCTNPGLVLAIEGPELDA
FVAAASAALAGKPSQVMLTAGIAATYRRQIDERAQQPDVARVADGVASDNACGALPVLFRAKAADFMANHGLAEEIFGPA
SIVVACRDEQELLGVLDGIEGQLTATLLLDPADYPVAKRVLPVLERKVGRILANGYPTGVEVCHAMVHGGPFPATSDSRT
TSVGTMAIDRFLRPVCYQDLPAELLPEALQDANPLGIWRLRDGELVRR
>Mature_527_residues
THEITGNMLLGAASVRGTQGVLRAFAPATGTELEPEFGAGGPADVDRACRLAGEAFDAFRAAPPDTRAALLEAIATGIEQ
LGATLIERLHLETALPVARLEGERARTCGQLRLFAQLVRDGRWNDATLDSALPERKPLPRADLRARKIPIGPVAVFGASN
FPLAFSVAGGDTASALAAGCPVVVKAHEAHLGGSELVGRAIQQAVAELGLPEGTFSLVIGKGNAVGEALVAHPAIKAVGF
TGSRRGGLALSAIAAARAEPIPVHAEMSSINPVLVLPAALKARGAQLAQGFVDSLVLGAGQFCTNPGLVLAIEGPELDAF
VAAASAALAGKPSQVMLTAGIAATYRRQIDERAQQPDVARVADGVASDNACGALPVLFRAKAADFMANHGLAEEIFGPAS
IVVACRDEQELLGVLDGIEGQLTATLLLDPADYPVAKRVLPVLERKVGRILANGYPTGVEVCHAMVHGGPFPATSDSRTT
SVGTMAIDRFLRPVCYQDLPAELLPEALQDANPLGIWRLRDGELVRR

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=433, Percent_Identity=23.5565819861432, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI153266822, Length=417, Percent_Identity=26.6187050359712, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081896, Length=423, Percent_Identity=28.8416075650118, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1788042, Length=325, Percent_Identity=29.2307692307692, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786504, Length=316, Percent_Identity=27.2151898734177, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787684, Length=401, Percent_Identity=26.9326683291771, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1787250, Length=267, Percent_Identity=28.8389513108614, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787558, Length=438, Percent_Identity=26.7123287671233, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17551164, Length=439, Percent_Identity=21.6400911161731, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI133930964, Length=272, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324950, Length=473, Percent_Identity=26.0042283298097, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320917, Length=429, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323821, Length=301, Percent_Identity=28.2392026578073, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323822, Length=302, Percent_Identity=29.4701986754967, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281362580, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472918, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472926, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62472936, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356737, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54801; Mature: 54669

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHEITGNMLLGAASVRGTQGVLRAFAPATGTELEPEFGAGGPADVDRACRLAGEAFDAF
CCCEECCCEEEECHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RAAPPDTRAALLEAIATGIEQLGATLIERLHLETALPVARLEGERARTCGQLRLFAQLVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHH
DGRWNDATLDSALPERKPLPRADLRARKIPIGPVAVFGASNFPLAFSVAGGDTASALAAG
CCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHCC
CPVVVKAHEAHLGGSELVGRAIQQAVAELGLPEGTFSLVIGKGNAVGEALVAHPAIKAVG
CCEEEEECHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
FTGSRRGGLALSAIAAARAEPIPVHAEMSSINPVLVLPAALKARGAQLAQGFVDSLVLGA
CCCCCCCCHHHHHHHHHCCCCCCEEEHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC
GQFCTNPGLVLAIEGPELDAFVAAASAALAGKPSQVMLTAGIAATYRRQIDERAQQPDVA
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHH
RVADGVASDNACGALPVLFRAKAADFMANHGLAEEIFGPASIVVACRDEQELLGVLDGIE
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCHHHHHHHHCCCC
GQLTATLLLDPADYPVAKRVLPVLERKVGRILANGYPTGVEVCHAMVHGGPFPATSDSRT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
TSVGTMAIDRFLRPVCYQDLPAELLPEALQDANPLGIWRLRDGELVRR
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHCC
>Mature Secondary Structure 
THEITGNMLLGAASVRGTQGVLRAFAPATGTELEPEFGAGGPADVDRACRLAGEAFDAF
CCEECCCEEEECHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RAAPPDTRAALLEAIATGIEQLGATLIERLHLETALPVARLEGERARTCGQLRLFAQLVR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHH
DGRWNDATLDSALPERKPLPRADLRARKIPIGPVAVFGASNFPLAFSVAGGDTASALAAG
CCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEECCCCHHHHHHCC
CPVVVKAHEAHLGGSELVGRAIQQAVAELGLPEGTFSLVIGKGNAVGEALVAHPAIKAVG
CCEEEEECHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
FTGSRRGGLALSAIAAARAEPIPVHAEMSSINPVLVLPAALKARGAQLAQGFVDSLVLGA
CCCCCCCCHHHHHHHHHCCCCCCEEEHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCC
GQFCTNPGLVLAIEGPELDAFVAAASAALAGKPSQVMLTAGIAATYRRQIDERAQQPDVA
CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCHH
RVADGVASDNACGALPVLFRAKAADFMANHGLAEEIFGPASIVVACRDEQELLGVLDGIE
HHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCEEEEEEECCHHHHHHHHCCCC
GQLTATLLLDPADYPVAKRVLPVLERKVGRILANGYPTGVEVCHAMVHGGPFPATSDSRT
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCC
TSVGTMAIDRFLRPVCYQDLPAELLPEALQDANPLGIWRLRDGELVRR
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]