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The map label for this gene is alr [H]

Identifier: 238025116

GI number: 238025116

Start: 2219493

End: 2220620

Strand: Direct

Name: alr [H]

Synonym: bglu_2g17750

Alternate gene names: 238025116

Gene position: 2219493-2220620 (Clockwise)

Preceding gene: 238025112

Following gene: 238025117

Centisome position: 78.5

GC content: 71.54

Gene sequence:

>1128_bases
ATGCCCCGTCCCATCGTCGCCCAGATCCGCCCCGCCGCCGTTCGCCACAATCTCGCCATCATCCGGCGCAAGGCCGCCGG
CACGCGCATCTGGGCCGTCGTGAAGGCCAACGCCTACGGCCACGGCATCGAGCGGATCTATCCGGCGCTCGCCGACGCGG
ACGGCATCGCGCTGCTCGACCTCGACGAAGCCGTGCGGGTGCGTGAGCTCGGCTGGACCCGGCCGGTGCTGCTGCTCGAG
GGGCTGTTCGACGCGTCCGACGTCGCGGTCGCGGACCGCTACCGGCTCACCGTGGCGGTCCACGGCGAGGAGCAGCTCGA
CATGCTCGCGAGCGCGCGCCCCAGCCGGCCGATCGACATCCAGCTCAAGATGAATTCCGGGATGAACCGCCTCGGCTTCC
GGCCGAGCGCGTTTCGCGCCGCCTGGGAGCGCGCCTCGGCCACGCCGGCAGTGGGCCGGATTGCGCTGATGACGCATTTC
GCCAACGCCGACGAAGGCGAGGTGGCATGGCAGACCCAGCAGTTCGACGCCGCCACCGAGGGCCTGCCCGGCGAGCGCTC
GCTGTCGAACTCGGCCGCGGTGCTCTGGCATCCGGACGCGCACCGCGACTGGGTGCGCCCCGGCACGATCCTGTACGGTG
CCTCGCCCACCGGTGCCACGCGACATATCGCCGACACCGGCCTGGTGCCGGCCATGACGCTGACGAGCCGGCTGATCGGC
GTGCAGACGATCGAGGAGAACGAGACGGTGGGTTATGGCCGGCGCTTCGCCGCCAAGCGCACGATGCGCATCGGCGTGGT
GGCGTGCGGCTACGCCGACGGCTACCCGCGCCACGCGCAGACCGGCACGCCAATCGCCGTGGACGGTATCGTGACGCGCG
TGGTCGGCCGCGTGTCGATGGACATGCTGACGGTGGACCTGACGCCATGCCCGAACGCGCGGGTGGGCTCGTCGGTCGAG
CTGTGGGGCGAACAGGTGCGCGTGGACGACGTGGCCGAGGCCTCCGGTACGATCGGTTACGAGCTGATGTGCGCGATCGC
GCGGCGCGTGCCGGTGGTGGTCGAGCCGCTGGTGGACGCGCCTGCGCTCGACATGCCGGTATTGCGCACCGGCAGCTACG
GGCGCTGA

Upstream 100 bases:

>100_bases
TGGCCGCCGAACCCAACTTTTCTCAATAATACGCGATCGACAGCCGGCCGGCCGCGAGGCCGCCCGGCCTGTGCCGCCCA
CGACATCGTCCGAGACAGCC

Downstream 100 bases:

>100_bases
ACGGCGCAGGCGGCGGCCGCTCCGGCCAGCCGCCGCGGCACGGCCTGCGCCGGCCCGCTGCCGGCCGACACGCGCCCTCC
ATTCGCGGGCTTGCCGCCGC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPRPIVAQIRPAAVRHNLAIIRRKAAGTRIWAVVKANAYGHGIERIYPALADADGIALLDLDEAVRVRELGWTRPVLLLE
GLFDASDVAVADRYRLTVAVHGEEQLDMLASARPSRPIDIQLKMNSGMNRLGFRPSAFRAAWERASATPAVGRIALMTHF
ANADEGEVAWQTQQFDAATEGLPGERSLSNSAAVLWHPDAHRDWVRPGTILYGASPTGATRHIADTGLVPAMTLTSRLIG
VQTIEENETVGYGRRFAAKRTMRIGVVACGYADGYPRHAQTGTPIAVDGIVTRVVGRVSMDMLTVDLTPCPNARVGSSVE
LWGEQVRVDDVAEASGTIGYELMCAIARRVPVVVEPLVDAPALDMPVLRTGSYGR

Sequences:

>Translated_375_residues
MPRPIVAQIRPAAVRHNLAIIRRKAAGTRIWAVVKANAYGHGIERIYPALADADGIALLDLDEAVRVRELGWTRPVLLLE
GLFDASDVAVADRYRLTVAVHGEEQLDMLASARPSRPIDIQLKMNSGMNRLGFRPSAFRAAWERASATPAVGRIALMTHF
ANADEGEVAWQTQQFDAATEGLPGERSLSNSAAVLWHPDAHRDWVRPGTILYGASPTGATRHIADTGLVPAMTLTSRLIG
VQTIEENETVGYGRRFAAKRTMRIGVVACGYADGYPRHAQTGTPIAVDGIVTRVVGRVSMDMLTVDLTPCPNARVGSSVE
LWGEQVRVDDVAEASGTIGYELMCAIARRVPVVVEPLVDAPALDMPVLRTGSYGR
>Mature_374_residues
PRPIVAQIRPAAVRHNLAIIRRKAAGTRIWAVVKANAYGHGIERIYPALADADGIALLDLDEAVRVRELGWTRPVLLLEG
LFDASDVAVADRYRLTVAVHGEEQLDMLASARPSRPIDIQLKMNSGMNRLGFRPSAFRAAWERASATPAVGRIALMTHFA
NADEGEVAWQTQQFDAATEGLPGERSLSNSAAVLWHPDAHRDWVRPGTILYGASPTGATRHIADTGLVPAMTLTSRLIGV
QTIEENETVGYGRRFAAKRTMRIGVVACGYADGYPRHAQTGTPIAVDGIVTRVVGRVSMDMLTVDLTPCPNARVGSSVEL
WGEQVRVDDVAEASGTIGYELMCAIARRVPVVVEPLVDAPALDMPVLRTGSYGR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=354, Percent_Identity=57.6271186440678, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI1790487, Length=342, Percent_Identity=44.1520467836257, Blast_Score=277, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40569; Mature: 40438

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPIVAQIRPAAVRHNLAIIRRKAAGTRIWAVVKANAYGHGIERIYPALADADGIALLD
CCCCCEECCCHHHHHHCHHEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
LDEAVRVRELGWTRPVLLLEGLFDASDVAVADRYRLTVAVHGEEQLDMLASARPSRPIDI
CHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECEEEEEEEECCHHHHHHHHHCCCCCCEEE
QLKMNSGMNRLGFRPSAFRAAWERASATPAVGRIALMTHFANADEGEVAWQTQQFDAATE
EEEECCCCHHHCCCCHHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCEEEEEHHCCHHHC
GLPGERSLSNSAAVLWHPDAHRDWVRPGTILYGASPTGATRHIADTGLVPAMTLTSRLIG
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHE
VQTIEENETVGYGRRFAAKRTMRIGVVACGYADGYPRHAQTGTPIAVDGIVTRVVGRVSM
EEEECCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHEE
DMLTVDLTPCPNARVGSSVELWGEQVRVDDVAEASGTIGYELMCAIARRVPVVVEPLVDA
EEEEEECCCCCCCCCCCCHHHHHCEEEHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCC
PALDMPVLRTGSYGR
CCCCCCEECCCCCCC
>Mature Secondary Structure 
PRPIVAQIRPAAVRHNLAIIRRKAAGTRIWAVVKANAYGHGIERIYPALADADGIALLD
CCCCEECCCHHHHHHCHHEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCEEEEE
LDEAVRVRELGWTRPVLLLEGLFDASDVAVADRYRLTVAVHGEEQLDMLASARPSRPIDI
CHHHHHHHHCCCCCHHHHHHHCCCCCCEEEECEEEEEEEECCHHHHHHHHHCCCCCCEEE
QLKMNSGMNRLGFRPSAFRAAWERASATPAVGRIALMTHFANADEGEVAWQTQQFDAATE
EEEECCCCHHHCCCCHHHHHHHHHCCCCCCHHHEEEEEECCCCCCCCEEEEEHHCCHHHC
GLPGERSLSNSAAVLWHPDAHRDWVRPGTILYGASPTGATRHIADTGLVPAMTLTSRLIG
CCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCCCHHCCCCCHHHHHHHHHHE
VQTIEENETVGYGRRFAAKRTMRIGVVACGYADGYPRHAQTGTPIAVDGIVTRVVGRVSM
EEEECCCCCCCCCHHHHHHHEEEEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHHHEE
DMLTVDLTPCPNARVGSSVELWGEQVRVDDVAEASGTIGYELMCAIARRVPVVVEPLVDA
EEEEEECCCCCCCCCCCCHHHHHCEEEHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCC
PALDMPVLRTGSYGR
CCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA