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The map label for this gene is oxyR [H]

Identifier: 238024676

GI number: 238024676

Start: 1681891

End: 1682808

Strand: Reverse

Name: oxyR [H]

Synonym: bglu_2g13050

Alternate gene names: 238024676

Gene position: 1682808-1681891 (Counterclockwise)

Preceding gene: 238024684

Following gene: 238024675

Centisome position: 59.52

GC content: 65.14

Gene sequence:

>918_bases
ATGGCCCTGACGCTCAGACAGCTCAAGTACTTCGTCGCGACCGCCGAGCTCGGACAGATCTCGCAGGCCGCGATCCAGCT
CACTATCTCGCAGTCGGCCGTGACGAGCGCGATCAAGGAGCTGGAGGACAGGCTTGGCACGCAACTGTTCGTGCGCACGT
CGGCGGGCGTGACGCTGACCGATACCGGGCGGCGTTTTCTCAATCACGCGTACACAATTCTGTCGTCGGTCGACGAGGCG
ATGCGGATCCCGAATCTCGAGAGCACGCTGACCGGCACGCTCGCGATCGCCGCAAGCTACACGGTGCTCGGCTACTTCCT
GCCGCATCACGTGCTGCGGCTCAATACGCTCTATCCACGCCTGACGATTAACCTGCACGAACTGAACCGCGAGTCGATCG
AGGAAGGGCTGATCGCGGGCCGCTACGACATGGCCGTGCTGCTCACGTCGAACGTGTCGAATCCGGAGCTCGTGCTGGAG
CCGGTGATTCATTCGGTGCGCAGGCTGTGGGTCGGTGCGCATCATCCGCTGCTGCGGCGCGAGAGCGTCACGTTCGCGGA
GGTCGCGCACGAGCCGTTCGTGATGCTGACGGTGGACGAGGCAGGGCAGACCGCGCTGCGTTACTGGAACGAGACGCCGT
ATCGGCCGAACGTGATCCTACGCACCTCGTCGGTCGAGGCGGTGCGCAGCATGGTCGCGAACGGCAGCGGTGTCGCCATC
CTGTCCGACATGGTGTATCGCCCGTGGTCGCTCGAAGGGCGGCGCATCGAGACGATCGTGTTGCGCGACCCGGTGCCGCC
GATGAGCGTCGGCCTCGCGTGGCGCAAGAACATCGAGTTGGGTCCCGCGATGCACGCGGTGCGCGACTATTTTCGGCACA
CTTTCATGGAGCCCCGGGCGCTGGGTGGCGGCCCCTGA

Upstream 100 bases:

>100_bases
GTTGCGACTGGCGGATGTGCGCGGGTCGGGCGGCCCCGGATCGCCGCGAAACGGGCGGTTGATATGATGTTTACCGTTCC
CCATCAGTTTTCCACCGCCC

Downstream 100 bases:

>100_bases
GAGCCATTTTTGCGGACGACTTGGCTTTGTAGTTGGCGGTTGAAGCCGAGCCGCATCGTGATGGCGCTGTCCGCGGTGTC
GATCGCACGGTTTCGGCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Morphology and auto-aggregation control protein [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDRLGTQLFVRTSAGVTLTDTGRRFLNHAYTILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTINLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSVRRLWVGAHHPLLRRESVTFAEVAHEPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKNIELGPAMHAVRDYFRHTFMEPRALGGGP

Sequences:

>Translated_305_residues
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDRLGTQLFVRTSAGVTLTDTGRRFLNHAYTILSSVDEA
MRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTINLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLE
PVIHSVRRLWVGAHHPLLRRESVTFAEVAHEPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKNIELGPAMHAVRDYFRHTFMEPRALGGGP
>Mature_304_residues
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDRLGTQLFVRTSAGVTLTDTGRRFLNHAYTILSSVDEAM
RIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPRLTINLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEP
VIHSVRRLWVGAHHPLLRRESVTFAEVAHEPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAIL
SDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKNIELGPAMHAVRDYFRHTFMEPRALGGGP

Specific function: Hydrogen peroxide sensor. Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS (a regulatory RNA), dps, fur and grxA. OxyR expression is negatively autoregulated by binding to a 43 bp region upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=30.9608540925267, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI157672245, Length=301, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=27.681660899654, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=27.8884462151394, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787879, Length=302, Percent_Identity=32.7814569536424, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=27.4576271186441, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788297, Length=259, Percent_Identity=28.957528957529, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1788887, Length=299, Percent_Identity=27.0903010033445, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=149, Percent_Identity=29.5302013422819, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787601, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=196, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788296, Length=244, Percent_Identity=25.4098360655738, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786401, Length=280, Percent_Identity=26.7857142857143, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789506, Length=278, Percent_Identity=23.3812949640288, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=248, Percent_Identity=24.5967741935484, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=145, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=290, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788626, Length=144, Percent_Identity=32.6388888888889, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=28.5714285714286, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34010; Mature: 33879

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDRLGTQLFVRTSAGVTLT
CCCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCEEEE
DTGRRFLNHAYTILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTINLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSVRRLWVGAHHPLLRR
EEEEHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHC
ESVTFAEVAHEPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKNIELGPAMHAVRDYFRHTFMEPRA
EHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
LGGGP
CCCCC
>Mature Secondary Structure 
ALTLRQLKYFVATAELGQISQAAIQLTISQSAVTSAIKELEDRLGTQLFVRTSAGVTLT
CCHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCEEEE
DTGRRFLNHAYTILSSVDEAMRIPNLESTLTGTLAIAASYTVLGYFLPHHVLRLNTLYPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTINLHELNRESIEEGLIAGRYDMAVLLTSNVSNPELVLEPVIHSVRRLWVGAHHPLLRR
EEEEHHHCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHC
ESVTFAEVAHEPFVMLTVDEAGQTALRYWNETPYRPNVILRTSSVEAVRSMVANGSGVAI
CCCHHHHHCCCCEEEEEECCCCCHHHHHCCCCCCCCCEEEEECHHHHHHHHHCCCCCCEE
LSDMVYRPWSLEGRRIETIVLRDPVPPMSVGLAWRKNIELGPAMHAVRDYFRHTFMEPRA
EHHHHCCCCCCCCCEEEEEEEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCC
LGGGP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]