Click here to switch to the map view.

The map label for this gene is pcaU [H]

Identifier: 238024556

GI number: 238024556

Start: 1476320

End: 1477090

Strand: Direct

Name: pcaU [H]

Synonym: bglu_2g11630

Alternate gene names: 238024556

Gene position: 1476320-1477090 (Clockwise)

Preceding gene: 238024555

Following gene: 238024568

Centisome position: 52.22

GC content: 71.47

Gene sequence:

>771_bases
ATGAAAAAAGCCCCTCTCGACAAGCGCGACTGGATCGCCGGCCTGGAAAAAGGCCTGATGATCCTCGAGGCGTTCGACAG
CGAACACGCGCGCATGACGCCGACCCAGGCGGCCGCGCGCACCGGCCTCACGCGCACCGCCGCGCGCCGCTACCTGCTCA
CGCTCGAGTCGCTCGGCTACGTGCACACCGACGGCAAGCTCTACGGCCTCACGCCGCGCGTGCTGCGGGTGGGCTGGTCC
TACTTCGACTCGGCGCGGCTGCCGCGCATGGTGCAGCCCTACCTGCAGCAGCTCAGCGCCACGCTGAACGCATCGGCCTA
CGTCAGCGTGCTCGACGACTGGGAGCTGGTGGTGATCGCACGCAACGGCGTGTCGCGCGTGATGACCACCGGCTTCGTGC
TCGGCGCGCGCGTGCCGGCGCCGCTCGCCTCGGCCGGCGTGGTGCTGCTGGCGCACCGCCACGCCGCCGCCGAAGTGGCC
GCCTGGCTCGACACCACCGAGCTGCCGCCCTACACGCCGCACACGCTGACCAACAAGACGCGGCTGCAGCAGACCATCGC
GCAGGCGCGCGAGAACGGCTACGCGCTGATCGAGCAGCAGCTGCAGGTGGGCGTGCGCGGCATCGCGGTGCCGCTGAAGA
ACCGCCAGGGCGAGGTGGTGGCCGCGCTCAGCACCAACATGCCGATCGGCGGCGAAGCGCCGGCCGCCGCGCTGGCGCGC
GTGCTGCCGCCGCTGCAGGAAACGGCGCTGGCGATGCTGAACGTGCTGTAG

Upstream 100 bases:

>100_bases
TCTCGCGCTCGGCTGCCTGATCTCGGTGCTGGTCGCCGCGCGCATGCGCGCGGCCTGAGCGCGGCCGGCAGCGAACGACG
GCGGCCGGCCGCTGGTTCCG

Downstream 100 bases:

>100_bases
CAGGCGCCGGCGCGTGCCGCCCGGCTTGCCTTGCCGGCAGGCAGGCGGCGGCGCGCATCGCGTCGGGCCGCGCGCGCCGC
CGCGCTCACTGCAGCATGAA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKKAPLDKRDWIAGLEKGLMILEAFDSEHARMTPTQAAARTGLTRTAARRYLLTLESLGYVHTDGKLYGLTPRVLRVGWS
YFDSARLPRMVQPYLQQLSATLNASAYVSVLDDWELVVIARNGVSRVMTTGFVLGARVPAPLASAGVVLLAHRHAAAEVA
AWLDTTELPPYTPHTLTNKTRLQQTIAQARENGYALIEQQLQVGVRGIAVPLKNRQGEVVAALSTNMPIGGEAPAAALAR
VLPPLQETALAMLNVL

Sequences:

>Translated_256_residues
MKKAPLDKRDWIAGLEKGLMILEAFDSEHARMTPTQAAARTGLTRTAARRYLLTLESLGYVHTDGKLYGLTPRVLRVGWS
YFDSARLPRMVQPYLQQLSATLNASAYVSVLDDWELVVIARNGVSRVMTTGFVLGARVPAPLASAGVVLLAHRHAAAEVA
AWLDTTELPPYTPHTLTNKTRLQQTIAQARENGYALIEQQLQVGVRGIAVPLKNRQGEVVAALSTNMPIGGEAPAAALAR
VLPPLQETALAMLNVL
>Mature_256_residues
MKKAPLDKRDWIAGLEKGLMILEAFDSEHARMTPTQAAARTGLTRTAARRYLLTLESLGYVHTDGKLYGLTPRVLRVGWS
YFDSARLPRMVQPYLQQLSATLNASAYVSVLDDWELVVIARNGVSRVMTTGFVLGARVPAPLASAGVVLLAHRHAAAEVA
AWLDTTELPPYTPHTLTNKTRLQQTIAQARENGYALIEQQLQVGVRGIAVPLKNRQGEVVAALSTNMPIGGEAPAAALAR
VLPPLQETALAMLNVL

Specific function: Activates transcription of the pca operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=244, Percent_Identity=29.0983606557377, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788131, Length=231, Percent_Identity=29.4372294372294, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI87082359, Length=222, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1789999, Length=246, Percent_Identity=26.4227642276423, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786715, Length=216, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27782; Mature: 27782

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAPLDKRDWIAGLEKGLMILEAFDSEHARMTPTQAAARTGLTRTAARRYLLTLESLGY
CCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCE
VHTDGKLYGLTPRVLRVGWSYFDSARLPRMVQPYLQQLSATLNASAYVSVLDDWELVVIA
EEECCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEEEECCCEEEEEE
RNGVSRVMTTGFVLGARVPAPLASAGVVLLAHRHAAAEVAAWLDTTELPPYTPHTLTNKT
CCCHHHHHHHHHHHCCCCCCCHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RLQQTIAQARENGYALIEQQLQVGVRGIAVPLKNRQGEVVAALSTNMPIGGEAPAAALAR
HHHHHHHHHHHCCHHHHHHHHHHCHHEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHH
VLPPLQETALAMLNVL
HCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKKAPLDKRDWIAGLEKGLMILEAFDSEHARMTPTQAAARTGLTRTAARRYLLTLESLGY
CCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCE
VHTDGKLYGLTPRVLRVGWSYFDSARLPRMVQPYLQQLSATLNASAYVSVLDDWELVVIA
EEECCEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEEEEECCCEEEEEE
RNGVSRVMTTGFVLGARVPAPLASAGVVLLAHRHAAAEVAAWLDTTELPPYTPHTLTNKT
CCCHHHHHHHHHHHCCCCCCCHHHCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RLQQTIAQARENGYALIEQQLQVGVRGIAVPLKNRQGEVVAALSTNMPIGGEAPAAALAR
HHHHHHHHHHHCCHHHHHHHHHHCHHEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHH
VLPPLQETALAMLNVL
HCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515921 [H]