Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 238024470

GI number: 238024470

Start: 1361618

End: 1363102

Strand: Direct

Name: tldD [H]

Synonym: bglu_2g10660

Alternate gene names: 238024470

Gene position: 1361618-1363102 (Clockwise)

Preceding gene: 238024469

Following gene: 238024471

Centisome position: 48.16

GC content: 71.45

Gene sequence:

>1485_bases
ATGAGTGAGGCAAAGCAATCGGGCGCGCGGCTTGCCGCGCGCGACGGGGTGAGTGCGCTGGCGCACGGCATCCTGCTGGA
ACAGCATGGCATCGACGAGACCGCGCTGTTTTCCGCAATGGGATCGGCCCTCGGCCAGCGAGGCGATTTCGCCGACCTCT
TCCTGAAGGAGACGACCGCGGAATCGTGGTCGCTGGAGGGCGGCGCCGTGCGCGGCAGCTCGTATCGACGCGACGCCGGC
TTCGGCCTGCGCGTCTTGAAGGGCGAGGAGGCCACGCTGGCGAGCTCGCAACGGATCGACGCGGCGGCACTTCGGCATGT
CGCGGCCCGGCTGCGCGGCACCGCCGACGGCGCCCCGCGGCACGGCGCGACGGCCGCGCCCCGCGCGCAGCTGCCCTTGG
CGCGGCCGCTCTACGAGGCCAGCCATCCGCTGGAGGCGATGGGCGCGGCGGACAAGATCGCGCTGCTGAAGCGGCTCGAC
GAGGCCGCGCGGGCCGCCGACTCGCGCGTGATCGAGGTGCATGCCGTGCTGAGCGCCGTGCACGAGGCGGTCTGGGTGGC
GCGTTGCGACGGCCTGAGCACGGGCGACGTGCGCCCGCTGCTGTCGCTCTGGATCAACGTTCGCGTCAGGTCCGGCGCGC
GCGAGGAGAGTGCGAGCGGCGGCATGGGCGGGCGCTACGGCGTCAGGACCTGGTCCGACGACGAACTGCGCGCGTTCGTG
CGCGAGCGGGTGTCGGCCGCGCTCACCAAACTGCGGTCGCAGCCGGCGCCGGCCGGAAAAATGACGGTGGTGGTCGGCCC
GGGCTGGAACGGCGTGCTGCTGCACGAAGCGGTCGGCCACGGGCTGGAGGCCGACGGCGTGCGGCGCGGGACCTCGGCCT
TCGCGGGACGCCTGGGAGAGCAGGTCGCCTCGCCGCACGTGACCATCGTCGACGACGGCACGCTGCAAGGCGGGCGCGGC
TCCTTGCATATCGACGACGAAGGGTGCGAGACGCGGCGCACGACCCTGATCGAGAACGGCGTGTTGTGCGGGTACATGCA
CGACGGGCTCAGCGCGCGGCTGATGCGCGCCGCGCCCACCGGGAACGGCCGCCGCGAGGGCTATGCGGCCTCGCCCATGC
CGCGCATGACGAACACGTTCATGCTCAATGGCGATCACGATCCGGGCGAGATCGTCGAGTCGGTGCGCCACGGCATCTAC
GTCTCGGGCCTGGAGGGCGGCCAGGTCGACATTACCAGCGGCCAGTTCGTCTTCGAGGCATCGGAAGCCTATCTGATCGA
GAACGGCAGGATCGCCGCGCCGCTCAAAGGCGCGACCATCACCGGACGCGGCCCGGACACCATCCGGCAGATCAGCATGG
TCGGCAACGATCTCGCCTGCGATCCCGGCAGGGCGTCCTGCAGCAAGGCGGGACAATGGATTCCGGTGGGCGTCGGCCAG
CCGACCGTGAGGGTCGACGAGATGATCGTCGGCGGGACCGCGTAG

Upstream 100 bases:

>100_bases
CGGCGGGCTGCAGGCGATCGGCAGCGACGCGATCACCCGGGGATGGGCGACGTCGGGATCGTGGCTGATCGATGCAATGA
TGGTCGGGGGGGCTTGAGGC

Downstream 100 bases:

>100_bases
TCATGGTCTCGAGGCGTGCGACGGCGGCGGGCGCGCAGGCGAACCCGTGGGCCTATCGTCTGCACCAGTCCAGCCGCCGG
CAGCGGGAGGCGAAGACGGA

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSEAKQSGARLAARDGVSALAHGILLEQHGIDETALFSAMGSALGQRGDFADLFLKETTAESWSLEGGAVRGSSYRRDAG
FGLRVLKGEEATLASSQRIDAAALRHVAARLRGTADGAPRHGATAAPRAQLPLARPLYEASHPLEAMGAADKIALLKRLD
EAARAADSRVIEVHAVLSAVHEAVWVARCDGLSTGDVRPLLSLWINVRVRSGAREESASGGMGGRYGVRTWSDDELRAFV
RERVSAALTKLRSQPAPAGKMTVVVGPGWNGVLLHEAVGHGLEADGVRRGTSAFAGRLGEQVASPHVTIVDDGTLQGGRG
SLHIDDEGCETRRTTLIENGVLCGYMHDGLSARLMRAAPTGNGRREGYAASPMPRMTNTFMLNGDHDPGEIVESVRHGIY
VSGLEGGQVDITSGQFVFEASEAYLIENGRIAAPLKGATITGRGPDTIRQISMVGNDLACDPGRASCSKAGQWIPVGVGQ
PTVRVDEMIVGGTA

Sequences:

>Translated_494_residues
MSEAKQSGARLAARDGVSALAHGILLEQHGIDETALFSAMGSALGQRGDFADLFLKETTAESWSLEGGAVRGSSYRRDAG
FGLRVLKGEEATLASSQRIDAAALRHVAARLRGTADGAPRHGATAAPRAQLPLARPLYEASHPLEAMGAADKIALLKRLD
EAARAADSRVIEVHAVLSAVHEAVWVARCDGLSTGDVRPLLSLWINVRVRSGAREESASGGMGGRYGVRTWSDDELRAFV
RERVSAALTKLRSQPAPAGKMTVVVGPGWNGVLLHEAVGHGLEADGVRRGTSAFAGRLGEQVASPHVTIVDDGTLQGGRG
SLHIDDEGCETRRTTLIENGVLCGYMHDGLSARLMRAAPTGNGRREGYAASPMPRMTNTFMLNGDHDPGEIVESVRHGIY
VSGLEGGQVDITSGQFVFEASEAYLIENGRIAAPLKGATITGRGPDTIRQISMVGNDLACDPGRASCSKAGQWIPVGVGQ
PTVRVDEMIVGGTA
>Mature_493_residues
SEAKQSGARLAARDGVSALAHGILLEQHGIDETALFSAMGSALGQRGDFADLFLKETTAESWSLEGGAVRGSSYRRDAGF
GLRVLKGEEATLASSQRIDAAALRHVAARLRGTADGAPRHGATAAPRAQLPLARPLYEASHPLEAMGAADKIALLKRLDE
AARAADSRVIEVHAVLSAVHEAVWVARCDGLSTGDVRPLLSLWINVRVRSGAREESASGGMGGRYGVRTWSDDELRAFVR
ERVSAALTKLRSQPAPAGKMTVVVGPGWNGVLLHEAVGHGLEADGVRRGTSAFAGRLGEQVASPHVTIVDDGTLQGGRGS
LHIDDEGCETRRTTLIENGVLCGYMHDGLSARLMRAAPTGNGRREGYAASPMPRMTNTFMLNGDHDPGEIVESVRHGIYV
SGLEGGQVDITSGQFVFEASEAYLIENGRIAAPLKGATITGRGPDTIRQISMVGNDLACDPGRASCSKAGQWIPVGVGQP
TVRVDEMIVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=480, Percent_Identity=49.7916666666667, Blast_Score=419, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51956; Mature: 51825

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKQSGARLAARDGVSALAHGILLEQHGIDETALFSAMGSALGQRGDFADLFLKETTA
CCCCHHHCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCC
ESWSLEGGAVRGSSYRRDAGFGLRVLKGEEATLASSQRIDAAALRHVAARLRGTADGAPR
CCCCCCCCEECCCCCCCCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC
HGATAAPRAQLPLARPLYEASHPLEAMGAADKIALLKRLDEAARAADSRVIEVHAVLSAV
CCCCCCCCCCCCCCCHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHH
HEAVWVARCDGLSTGDVRPLLSLWINVRVRSGAREESASGGMGGRYGVRTWSDDELRAFV
HHHHHHHCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
RERVSAALTKLRSQPAPAGKMTVVVGPGWNGVLLHEAVGHGLEADGVRRGTSAFAGRLGE
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHH
QVASPHVTIVDDGTLQGGRGSLHIDDEGCETRRTTLIENGVLCGYMHDGLSARLMRAAPT
HHCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHCCCEEEEEECCCCHHHEEEECCC
GNGRREGYAASPMPRMTNTFMLNGDHDPGEIVESVRHGIYVSGLEGGQVDITSGQFVFEA
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCEEEECCCCCEEEEECCCEEEEC
SEAYLIENGRIAAPLKGATITGRGPDTIRQISMVGNDLACDPGRASCSKAGQWIPVGVGQ
CCEEEEECCEEECCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECCCC
PTVRVDEMIVGGTA
CCEEECCEEECCCC
>Mature Secondary Structure 
SEAKQSGARLAARDGVSALAHGILLEQHGIDETALFSAMGSALGQRGDFADLFLKETTA
CCCHHHCCHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCC
ESWSLEGGAVRGSSYRRDAGFGLRVLKGEEATLASSQRIDAAALRHVAARLRGTADGAPR
CCCCCCCCEECCCCCCCCCCCCEEEEECCCHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC
HGATAAPRAQLPLARPLYEASHPLEAMGAADKIALLKRLDEAARAADSRVIEVHAVLSAV
CCCCCCCCCCCCCCCHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHH
HEAVWVARCDGLSTGDVRPLLSLWINVRVRSGAREESASGGMGGRYGVRTWSDDELRAFV
HHHHHHHCCCCCCCCCHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
RERVSAALTKLRSQPAPAGKMTVVVGPGWNGVLLHEAVGHGLEADGVRRGTSAFAGRLGE
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHH
QVASPHVTIVDDGTLQGGRGSLHIDDEGCETRRTTLIENGVLCGYMHDGLSARLMRAAPT
HHCCCCEEEEECCCCCCCCCEEEECCCCCCHHHHHHHCCCEEEEEECCCCHHHEEEECCC
GNGRREGYAASPMPRMTNTFMLNGDHDPGEIVESVRHGIYVSGLEGGQVDITSGQFVFEA
CCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCEEEECCCCCEEEEECCCEEEEC
SEAYLIENGRIAAPLKGATITGRGPDTIRQISMVGNDLACDPGRASCSKAGQWIPVGVGQ
CCEEEEECCEEECCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHCCCEEEECCCC
PTVRVDEMIVGGTA
CCEEECCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]