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The map label for this gene is exbB [H]

Identifier: 238024465

GI number: 238024465

Start: 1355966

End: 1356700

Strand: Direct

Name: exbB [H]

Synonym: bglu_2g10610

Alternate gene names: 238024465

Gene position: 1355966-1356700 (Clockwise)

Preceding gene: 238024464

Following gene: 238024466

Centisome position: 47.96

GC content: 66.53

Gene sequence:

>735_bases
ATGGAACAGTACGGCATCGCCAATGTCTGGCAGCAGGGTGATTTCATCACCCGCTTCATCTTCGTCTTTCTTCTCGGCAT
GTCGGTCGTGTCCTGGTTCGTCATCGTGACCAAGGGACTGGCGAATCGACGCCTCGAGACCATGGGCAAGCGCGCGCAGA
CGCGCTTCTGGTCCACCCCGTCGTTCGACGAAGGCATCAAGGCGCTCGGCGACGGCGCCGACAATCCCTATCGCGCCATG
GCGCTGGCGGGCCGCGAGGCCAACGAGCAGCAGGCGGGAGGCGGCGCCTCGCTGCAAGGCAGCCTGAGTGCCAGCGAATG
GGTGGCCCGCGGCCTGCGCAATGCCTTCGACGACGAGGTCGCCCGCCTGCAGAACGGCCTGGCCGTGCTCGGCTCGATCG
GCAGCACCGCGCCGTTTGTCGGCCTGTTCGGCACGGTGTGGGGCATCTATCACGCGCTGATGGCGATCGGCGCATCGGGC
CAGGCCAGCCTCGACCACGTCGCCGGCCCGGTGGGCGAGTCGCTGATCATGACGGCGATCGGCTTGTTCGTGGCGATTCC
CGCCGTGCTCGGCTTCAACTACGTCAATCGCGGCAACAAGCGGGTCAGCCATCGCCTGAACCGGTTCGTGCATGAACTGC
ACGTGTATTTCGTGACGGGCGCCAAGGCCCACTGCGACGTTCGCCAGGCACCTGCGGCACCGGTGGCGAGCAAGCGCGTC
AGCGCCACTGCCTGA

Upstream 100 bases:

>100_bases
GCCATCCCTATACGACCGCCGGCATTGCCCGCGCCGTCGAGGCCGAGCAGCGGATCGCCTTCAATCTGAATGACTGACCT
GGAATTCAACGGAGCAAACA

Downstream 100 bases:

>100_bases
GCGGGGAGTTCATCGTGTCGATTCTCATGGATGGCAACAACGACGAAGGCGTGATGAACGACATCAACATGACGCCGCTG
ATCGACGTCATGTTGGTATT

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MEQYGIANVWQQGDFITRFIFVFLLGMSVVSWFVIVTKGLANRRLETMGKRAQTRFWSTPSFDEGIKALGDGADNPYRAM
ALAGREANEQQAGGGASLQGSLSASEWVARGLRNAFDDEVARLQNGLAVLGSIGSTAPFVGLFGTVWGIYHALMAIGASG
QASLDHVAGPVGESLIMTAIGLFVAIPAVLGFNYVNRGNKRVSHRLNRFVHELHVYFVTGAKAHCDVRQAPAAPVASKRV
SATA

Sequences:

>Translated_244_residues
MEQYGIANVWQQGDFITRFIFVFLLGMSVVSWFVIVTKGLANRRLETMGKRAQTRFWSTPSFDEGIKALGDGADNPYRAM
ALAGREANEQQAGGGASLQGSLSASEWVARGLRNAFDDEVARLQNGLAVLGSIGSTAPFVGLFGTVWGIYHALMAIGASG
QASLDHVAGPVGESLIMTAIGLFVAIPAVLGFNYVNRGNKRVSHRLNRFVHELHVYFVTGAKAHCDVRQAPAAPVASKRV
SATA
>Mature_244_residues
MEQYGIANVWQQGDFITRFIFVFLLGMSVVSWFVIVTKGLANRRLETMGKRAQTRFWSTPSFDEGIKALGDGADNPYRAM
ALAGREANEQQAGGGASLQGSLSASEWVARGLRNAFDDEVARLQNGLAVLGSIGSTAPFVGLFGTVWGIYHALMAIGASG
QASLDHVAGPVGESLIMTAIGLFVAIPAVLGFNYVNRGNKRVSHRLNRFVHELHVYFVTGAKAHCDVRQAPAAPVASKRV
SATA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=213, Percent_Identity=29.5774647887324, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1789381, Length=197, Percent_Identity=28.9340101522843, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26127; Mature: 26127

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCC
>Mature Secondary Structure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CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]