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The map label for this gene is mhpT [H]

Identifier: 238024460

GI number: 238024460

Start: 1348311

End: 1349558

Strand: Reverse

Name: mhpT [H]

Synonym: bglu_2g10560

Alternate gene names: 238024460

Gene position: 1349558-1348311 (Counterclockwise)

Preceding gene: 238024475

Following gene: 238024459

Centisome position: 47.73

GC content: 70.27

Gene sequence:

>1248_bases
GTGAAAAGAGCTGAATCATCCACTTCGTTCGGCAGCGGGAACGATGGCGCGACGACCGTTCGCGCAAGTGCCGCCGTCAC
CCTGGGCCTGTGTTTCGCGGTCGCGTTGCTCGAGGGACTCGATCTGCAGTCGGTCGGCGTCGCGGCACCGCGCATGGCGC
GCGAGTTCGGCCTGTCGGTCGCACAGATGGGCGTGGTGTTCAGCGCCGGCACCTTCGGCCTGCTGCCCGGCGCGATGCTC
GGCGGCCGGCTGGCCGATCTGCTTGGCCGCAAGCGCGTGCTGGTGATTTCCGTCTGCCTGTTCGGCCTGCTGTCGATCAT
GACCGCGCTGGTCCGCGATCTTCAGATGCTGGCGCTGGTGCGGATCCTCACCGGGATCGGGCTGGGCGGCGCACTGCCGA
ACCTGATCGCCCTGTCCTCGGAGGCGGTCGAGCCGCGCTCGCGCGGCACGGCCGTCAGCGTGATGTATTGCGGCATCCCG
TTCGGCGGACTGATCGCGTCGGTGATCGGCATGCTGAGCGCCGGCGACACCGAATGGCGGCATATCTTCTACGTCGGCGG
CGCGGGCCCGCTGCTGCTGGTGCCGCTGCTGCTCGCCTTGCTGGGGAATTCGCGGGCCTTCGCGCAGGCGTCCGACTACG
GCCGCGCGAAGCCGGCGCCGGTCGGCCGGATTCTGTTCGACGAGGCGCGCGGGCCGTCCACCGTGCAGATCTGGGTCAGC
TTCTTCTGCACGCTGATCGTCCTCTACTTCCTGCTCAACTGGCTGCCCTCGCTGATGGCGGCCAGCGGCCTGTCGCGCGT
GCAGGTGGGCTACGTGCAGATCCTCTTCAACATCGGCGGCGGGCTCGGCGCGCTGTTCATCGGCACGTTGATGGATCGCG
TGCGCCCCAGCCTGGTGGTGTCGGGCATGTATGCCGGCATCATCGCATCGCTCGCGGCGCTGGCAACGGCGCCCGGGTTC
GGCACCTTCGCCGCGGCGGCCTTTTTCGCCGGCATGTTCGTGGTCGGCGGCCAATCGGTGCTCTATGCGCTGTCGGCGCA
GTTCTACCCGACGGCGATGCGCGGCACCGGGGTCGGCGCGGCGGTGGCGGTCGGGCGCCTCGGCTCGGTGGTCGGGCCGC
TCGCGGCCGGCCAATTGCTGGCGATGGGCCGCAGCTCGTCGACGGTGATCGGCGCGTCCATCCCCGTCACGCTGATCGCC
GCCGCCGCCGCGCTGCTGCTGGTGCGTCGCCCGCGAGCCGCCGACTGA

Upstream 100 bases:

>100_bases
GCTGCATGCCTGCGCCGCAAGAACACCTCGCATTGACAGACGAGGCGAGCTCATTTGGGCCCGGCTGCTTCAATCGTCAC
AAAATAATCAGGATTACTAC

Downstream 100 bases:

>100_bases
ACGCGCGCCCCCGCACCAGACACCCATAACCACCAACGACATTGCGAATCCGGCAGTTCCTCAACGGTTTGGAGACACCA
CTCATGCAAGCATCCGCCAA

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MKRAESSTSFGSGNDGATTVRASAAVTLGLCFAVALLEGLDLQSVGVAAPRMAREFGLSVAQMGVVFSAGTFGLLPGAML
GGRLADLLGRKRVLVISVCLFGLLSIMTALVRDLQMLALVRILTGIGLGGALPNLIALSSEAVEPRSRGTAVSVMYCGIP
FGGLIASVIGMLSAGDTEWRHIFYVGGAGPLLLVPLLLALLGNSRAFAQASDYGRAKPAPVGRILFDEARGPSTVQIWVS
FFCTLIVLYFLLNWLPSLMAASGLSRVQVGYVQILFNIGGGLGALFIGTLMDRVRPSLVVSGMYAGIIASLAALATAPGF
GTFAAAAFFAGMFVVGGQSVLYALSAQFYPTAMRGTGVGAAVAVGRLGSVVGPLAAGQLLAMGRSSSTVIGASIPVTLIA
AAAALLLVRRPRAAD

Sequences:

>Translated_415_residues
MKRAESSTSFGSGNDGATTVRASAAVTLGLCFAVALLEGLDLQSVGVAAPRMAREFGLSVAQMGVVFSAGTFGLLPGAML
GGRLADLLGRKRVLVISVCLFGLLSIMTALVRDLQMLALVRILTGIGLGGALPNLIALSSEAVEPRSRGTAVSVMYCGIP
FGGLIASVIGMLSAGDTEWRHIFYVGGAGPLLLVPLLLALLGNSRAFAQASDYGRAKPAPVGRILFDEARGPSTVQIWVS
FFCTLIVLYFLLNWLPSLMAASGLSRVQVGYVQILFNIGGGLGALFIGTLMDRVRPSLVVSGMYAGIIASLAALATAPGF
GTFAAAAFFAGMFVVGGQSVLYALSAQFYPTAMRGTGVGAAVAVGRLGSVVGPLAAGQLLAMGRSSSTVIGASIPVTLIA
AAAALLLVRRPRAAD
>Mature_415_residues
MKRAESSTSFGSGNDGATTVRASAAVTLGLCFAVALLEGLDLQSVGVAAPRMAREFGLSVAQMGVVFSAGTFGLLPGAML
GGRLADLLGRKRVLVISVCLFGLLSIMTALVRDLQMLALVRILTGIGLGGALPNLIALSSEAVEPRSRGTAVSVMYCGIP
FGGLIASVIGMLSAGDTEWRHIFYVGGAGPLLLVPLLLALLGNSRAFAQASDYGRAKPAPVGRILFDEARGPSTVQIWVS
FFCTLIVLYFLLNWLPSLMAASGLSRVQVGYVQILFNIGGGLGALFIGTLMDRVRPSLVVSGMYAGIIASLAALATAPGF
GTFAAAAFFAGMFVVGGQSVLYALSAQFYPTAMRGTGVGAAVAVGRLGSVVGPLAAGQLLAMGRSSSTVIGASIPVTLIA
AAAALLLVRRPRAAD

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=231, Percent_Identity=25.974025974026, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI87081723, Length=388, Percent_Identity=49.2268041237113, Blast_Score=324, Evalue=7e-90,
Organism=Escherichia coli, GI1789152, Length=421, Percent_Identity=23.2779097387173, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786229, Length=397, Percent_Identity=24.6851385390428, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082404, Length=342, Percent_Identity=23.6842105263158, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42390; Mature: 42390

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRAESSTSFGSGNDGATTVRASAAVTLGLCFAVALLEGLDLQSVGVAAPRMAREFGLSV
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
AQMGVVFSAGTFGLLPGAMLGGRLADLLGRKRVLVISVCLFGLLSIMTALVRDLQMLALV
HHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTGIGLGGALPNLIALSSEAVEPRSRGTAVSVMYCGIPFGGLIASVIGMLSAGDTEWR
HHHHHCCCCHHHHHHHHHCCHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCE
HIFYVGGAGPLLLVPLLLALLGNSRAFAQASDYGRAKPAPVGRILFDEARGPSTVQIWVS
EEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
FFCTLIVLYFLLNWLPSLMAASGLSRVQVGYVQILFNIGGGLGALFIGTLMDRVRPSLVV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHH
SGMYAGIIASLAALATAPGFGTFAAAAFFAGMFVVGGQSVLYALSAQFYPTAMRGTGVGA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCCHH
AVAVGRLGSVVGPLAAGQLLAMGRSSSTVIGASIPVTLIAAAAALLLVRRPRAAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRAESSTSFGSGNDGATTVRASAAVTLGLCFAVALLEGLDLQSVGVAAPRMAREFGLSV
CCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
AQMGVVFSAGTFGLLPGAMLGGRLADLLGRKRVLVISVCLFGLLSIMTALVRDLQMLALV
HHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTGIGLGGALPNLIALSSEAVEPRSRGTAVSVMYCGIPFGGLIASVIGMLSAGDTEWR
HHHHHCCCCHHHHHHHHHCCHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCE
HIFYVGGAGPLLLVPLLLALLGNSRAFAQASDYGRAKPAPVGRILFDEARGPSTVQIWVS
EEEEECCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHH
FFCTLIVLYFLLNWLPSLMAASGLSRVQVGYVQILFNIGGGLGALFIGTLMDRVRPSLVV
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHH
SGMYAGIIASLAALATAPGFGTFAAAAFFAGMFVVGGQSVLYALSAQFYPTAMRGTGVGA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCCCCHH
AVAVGRLGSVVGPLAAGQLLAMGRSSSTVIGASIPVTLIAAAAALLLVRRPRAAD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]