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The map label for this gene is lrp [H]

Identifier: 238024433

GI number: 238024433

Start: 1317714

End: 1318205

Strand: Reverse

Name: lrp [H]

Synonym: bglu_2g10290

Alternate gene names: 238024433

Gene position: 1318205-1317714 (Counterclockwise)

Preceding gene: 339717972

Following gene: 238024432

Centisome position: 46.62

GC content: 62.4

Gene sequence:

>492_bases
ATGACGGACAGCAAGCTGGATCGCATCGACCTGCGCATCCTCTCCCAGTTGCAAAAGCGCGGCCGCATGACCAATGTCGA
GCTTGCCGAGGCGGTCGGACTCTCGCCGAGCCCCTGCCTGATTCGCGTGAAGCGGCTCGAGAAGGCCGGCTACATCGGCG
GCTACGGCGCGCACATCCAGCTCGAGAAGCTCGGCGACGTGCAGGTGGTGTTCACCGAGGTCACGCTCGCCGACCACCGG
CGCGAGGATTTCGACCGCTTCGTCGCGGCGATCCGCCTGGTCGACGAGATCGTCGAGTGCCACCTCGCGAGCGGCGGCTA
CGACTATCTGCTCAAGTTCATCACGCGCAGCGTGAGCCATTACCAGACGATCGTCGAAGGGCTGCTCGAGCAGAACATCG
GCATCGAGAAGTATTTCAGCTACGTGATCATCAAGTCGCCGTTCGTCAAACGGCATTACCCGCTCGAATCGCTGTTCGGC
GACCGTCACTGA

Upstream 100 bases:

>100_bases
GCTTGAGCCCGGCGGCCCGGCAAGGGAAAGCCGGGCTTGTGGCGCTCATCGATCGACTCTAAAGTAACCGGACATTCCAT
TTACGCCTTCTCACGTGAAC

Downstream 100 bases:

>100_bases
CGACGCTCGGCCGGCACCTCGAACGCGGCGCCGCGCTGCCCGCGTGGGGTTGCCGCGCCGCGCGCTGCCGCCGCAGCGCC
TCATCCAAGGATTTGCCATG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTDSKLDRIDLRILSQLQKRGRMTNVELAEAVGLSPSPCLIRVKRLEKAGYIGGYGAHIQLEKLGDVQVVFTEVTLADHR
REDFDRFVAAIRLVDEIVECHLASGGYDYLLKFITRSVSHYQTIVEGLLEQNIGIEKYFSYVIIKSPFVKRHYPLESLFG
DRH

Sequences:

>Translated_163_residues
MTDSKLDRIDLRILSQLQKRGRMTNVELAEAVGLSPSPCLIRVKRLEKAGYIGGYGAHIQLEKLGDVQVVFTEVTLADHR
REDFDRFVAAIRLVDEIVECHLASGGYDYLLKFITRSVSHYQTIVEGLLEQNIGIEKYFSYVIIKSPFVKRHYPLESLFG
DRH
>Mature_162_residues
TDSKLDRIDLRILSQLQKRGRMTNVELAEAVGLSPSPCLIRVKRLEKAGYIGGYGAHIQLEKLGDVQVVFTEVTLADHRR
EDFDRFVAAIRLVDEIVECHLASGGYDYLLKFITRSVSHYQTIVEGLLEQNIGIEKYFSYVIIKSPFVKRHYPLESLFGD
RH

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=43.7086092715232, Blast_Score=120, Evalue=3e-29,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=29.1390728476821, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790182, Length=154, Percent_Identity=24.025974025974, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18655; Mature: 18524

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSKLDRIDLRILSQLQKRGRMTNVELAEAVGLSPSPCLIRVKRLEKAGYIGGYGAHIQ
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEE
LEKLGDVQVVFTEVTLADHRREDFDRFVAAIRLVDEIVECHLASGGYDYLLKFITRSVSH
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YQTIVEGLLEQNIGIEKYFSYVIIKSPFVKRHYPLESLFGDRH
HHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCHHHHCCCCC
>Mature Secondary Structure 
TDSKLDRIDLRILSQLQKRGRMTNVELAEAVGLSPSPCLIRVKRLEKAGYIGGYGAHIQ
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEE
LEKLGDVQVVFTEVTLADHRREDFDRFVAAIRLVDEIVECHLASGGYDYLLKFITRSVSH
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YQTIVEGLLEQNIGIEKYFSYVIIKSPFVKRHYPLESLFGDRH
HHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]