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The map label for this gene is soxA [H]

Identifier: 238024357

GI number: 238024357

Start: 1169455

End: 1170783

Strand: Direct

Name: soxA [H]

Synonym: bglu_2g09500

Alternate gene names: 238024357

Gene position: 1169455-1170783 (Clockwise)

Preceding gene: 238024356

Following gene: 238024359

Centisome position: 41.36

GC content: 64.26

Gene sequence:

>1329_bases
ATGCTGCTGGTCGAAGAAGTGTACGACACGCCCGAATTTTCAGGCGCCGTCGACGTGGTCGTAATCGGCGCGGGGATCGT
CGGGACCGCTACCGCCTACGAATTGGCGCGACGCGGTGTGTCAGTCGCCCTGATCGACAAGGGCATGGTGGGCGGGGAGC
AATCGGGGCGCAACTGGGGCTGGGTTCGCCAGCAGAATCGCGACCTCTTCGAGCTGCCGCTTGCCATGCGCAGCCTGCGC
CGCTGGAGCGAGTTGCGCGATGAAATCCAGATCGACCTGGGTTTTCGGCGCGAAGGTATTCTTTACGCCAGCAACGACGC
GAAGGCCATCGCTCGATGGGAGGCTTGGTGCAGGCAGGCGCGCGAAATCGGTTTTGTCAGTCATCTGCTCAGCGCTCACG
AAATCAACAGCCGTGCTCCACAAGGCGGCCCCCGCTACGCCGGGGGAGTCTGGTCGCCCGACGACGGCCGCGCGGAACCT
TCGCGCGCGGCCTCGGCCCTTGCCGAGGGTGCGAAGCGACGGGGGGCCGTGCTTTATCAGAATTGCGCGGCACGCGGCCT
GGAGCTCAGCGCCGGGCGTGTCGGCGGCGTGTGGACGGAGCGCGGCCTGATCAAGGCAGGCGCGGTGGTATGTGCCGGCG
GTGCGTGGAGTTCCCGCTTTTGCAAGCGTCACGAGATCGACCTGCCGGTTGTCAACGTGATTGGCACGACGATGCGCACG
TCCGCGGCGGCAAGCGTGATCAACGGTTGTTTCAGCGGCCCCGGGTTTGCGATCCGTCGCCGGCTGGACGGCGGATATAC
GCTGGCTGTTCCCGGTTACGGGCGCATCGACCTGGCACCGCTCGGCCTGCGAAACGCGCTACGGTATCGCCGCAATTACC
GCAACGAGATTGGCAAGAAGCTCAAATACCGGCTTGCCAAACCGTGGTTCGACGGTCCCGAGGCATCGGCGAGCTGGCAA
TTCGATCAGGTCTCTCCGTTCGAACGCTGCCGCGTGCTCGACCCGAAGCCCGATCTCGAGTTCGTGAAAATCGCGTTGGA
CAACGTCAGGCGCGCGATTCCCCAGTTGTCCGAACTGAGGGTGGTGCACGCTTGGGCCGGGGCAATCGACACCACGCCCG
ACCTGATTCCCATCGTCTCCGACATCGCGGCCTTGCCGGGATTTTATGTGGCGACCGGATTCAGCGGCCATGGGTTCGCC
TTGGGCCCGGCGGCCGGAGAACTGGTCGCCGATATGGTGATGGGGGCGAAACCGCTGATAGATACCTCGCCGTACCGATT
GAGCCGTTTCACTGACGGCACGTTCATCAAGACCCCGGAAATGATGTGA

Upstream 100 bases:

>100_bases
TGTGTTGACGCAGCGCGCCGAGGGTCCGCACGCGAACGACGGCAGCACCGGAGCCGCGGCATGACCGGCGGCTGCGTCAA
TCGAATGAGGGAAGTCTGAA

Downstream 100 bases:

>100_bases
GGGCGCATGTCAGCGGCACTGCGCTTCGCCTCGTCAGCGGTTGCGCGAACGCGGCATCGAGCCCGTGATCGCTAGGCCGC
GCATCGCGCATGGCAGGGGC

Product: putative FAD dependent oxidoreductase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MLLVEEVYDTPEFSGAVDVVVIGAGIVGTATAYELARRGVSVALIDKGMVGGEQSGRNWGWVRQQNRDLFELPLAMRSLR
RWSELRDEIQIDLGFRREGILYASNDAKAIARWEAWCRQAREIGFVSHLLSAHEINSRAPQGGPRYAGGVWSPDDGRAEP
SRAASALAEGAKRRGAVLYQNCAARGLELSAGRVGGVWTERGLIKAGAVVCAGGAWSSRFCKRHEIDLPVVNVIGTTMRT
SAAASVINGCFSGPGFAIRRRLDGGYTLAVPGYGRIDLAPLGLRNALRYRRNYRNEIGKKLKYRLAKPWFDGPEASASWQ
FDQVSPFERCRVLDPKPDLEFVKIALDNVRRAIPQLSELRVVHAWAGAIDTTPDLIPIVSDIAALPGFYVATGFSGHGFA
LGPAAGELVADMVMGAKPLIDTSPYRLSRFTDGTFIKTPEMM

Sequences:

>Translated_442_residues
MLLVEEVYDTPEFSGAVDVVVIGAGIVGTATAYELARRGVSVALIDKGMVGGEQSGRNWGWVRQQNRDLFELPLAMRSLR
RWSELRDEIQIDLGFRREGILYASNDAKAIARWEAWCRQAREIGFVSHLLSAHEINSRAPQGGPRYAGGVWSPDDGRAEP
SRAASALAEGAKRRGAVLYQNCAARGLELSAGRVGGVWTERGLIKAGAVVCAGGAWSSRFCKRHEIDLPVVNVIGTTMRT
SAAASVINGCFSGPGFAIRRRLDGGYTLAVPGYGRIDLAPLGLRNALRYRRNYRNEIGKKLKYRLAKPWFDGPEASASWQ
FDQVSPFERCRVLDPKPDLEFVKIALDNVRRAIPQLSELRVVHAWAGAIDTTPDLIPIVSDIAALPGFYVATGFSGHGFA
LGPAAGELVADMVMGAKPLIDTSPYRLSRFTDGTFIKTPEMM
>Mature_442_residues
MLLVEEVYDTPEFSGAVDVVVIGAGIVGTATAYELARRGVSVALIDKGMVGGEQSGRNWGWVRQQNRDLFELPLAMRSLR
RWSELRDEIQIDLGFRREGILYASNDAKAIARWEAWCRQAREIGFVSHLLSAHEINSRAPQGGPRYAGGVWSPDDGRAEP
SRAASALAEGAKRRGAVLYQNCAARGLELSAGRVGGVWTERGLIKAGAVVCAGGAWSSRFCKRHEIDLPVVNVIGTTMRT
SAAASVINGCFSGPGFAIRRRLDGGYTLAVPGYGRIDLAPLGLRNALRYRRNYRNEIGKKLKYRLAKPWFDGPEASASWQ
FDQVSPFERCRVLDPKPDLEFVKIALDNVRRAIPQLSELRVVHAWAGAIDTTPDLIPIVSDIAALPGFYVATGFSGHGFA
LGPAAGELVADMVMGAKPLIDTSPYRLSRFTDGTFIKTPEMM

Specific function: Catalyzes the oxidative demethylation of sarcosine. Can also oxidize other secondary amino acids such as N-methyl-L- alanine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=426, Percent_Identity=24.1784037558685, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI21361378, Length=426, Percent_Identity=24.1784037558685, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI24797151, Length=427, Percent_Identity=21.7798594847775, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI1787559, Length=443, Percent_Identity=24.8306997742664, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130091, Length=222, Percent_Identity=29.7297297297297, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 48206; Mature: 48206

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVEEVYDTPEFSGAVDVVVIGAGIVGTATAYELARRGVSVALIDKGMVGGEQSGRNWG
CEEHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
WVRQQNRDLFELPLAMRSLRRWSELRDEIQIDLGFRREGILYASNDAKAIARWEAWCRQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEECCCHHHHHHHHHHHHHH
REIGFVSHLLSAHEINSRAPQGGPRYAGGVWSPDDGRAEPSRAASALAEGAKRRGAVLYQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEH
NCAARGLELSAGRVGGVWTERGLIKAGAVVCAGGAWSSRFCKRHEIDLPVVNVIGTTMRT
HHHCCCCEECCCCCCCEECCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHH
SAAASVINGCFSGPGFAIRRRLDGGYTLAVPGYGRIDLAPLGLRNALRYRRNYRNEIGKK
HHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHH
LKYRLAKPWFDGPEASASWQFDQVSPFERCRVLDPKPDLEFVKIALDNVRRAIPQLSELR
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHHCHHHHHE
VVHAWAGAIDTTPDLIPIVSDIAALPGFYVATGFSGHGFALGPAAGELVADMVMGAKPLI
EHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHCCCCCC
DTSPYRLSRFTDGTFIKTPEMM
CCCCCEEEECCCCCEECCCCCC
>Mature Secondary Structure
MLLVEEVYDTPEFSGAVDVVVIGAGIVGTATAYELARRGVSVALIDKGMVGGEQSGRNWG
CEEHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCC
WVRQQNRDLFELPLAMRSLRRWSELRDEIQIDLGFRREGILYASNDAKAIARWEAWCRQA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEEECCCHHHHHHHHHHHHHH
REIGFVSHLLSAHEINSRAPQGGPRYAGGVWSPDDGRAEPSRAASALAEGAKRRGAVLYQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEH
NCAARGLELSAGRVGGVWTERGLIKAGAVVCAGGAWSSRFCKRHEIDLPVVNVIGTTMRT
HHHCCCCEECCCCCCCEECCCCCCCCCCEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHH
SAAASVINGCFSGPGFAIRRRLDGGYTLAVPGYGRIDLAPLGLRNALRYRRNYRNEIGKK
HHHHHHHHHHCCCCCHHEEEECCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHH
LKYRLAKPWFDGPEASASWQFDQVSPFERCRVLDPKPDLEFVKIALDNVRRAIPQLSELR
HHHHHCCCCCCCCCCCCCCCCCCCCHHHHCEECCCCCCHHHHHHHHHHHHHHHCHHHHHE
VVHAWAGAIDTTPDLIPIVSDIAALPGFYVATGFSGHGFALGPAAGELVADMVMGAKPLI
EHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEECCHHHHHHHHHHHCCCCCC
DTSPYRLSRFTDGTFIKTPEMM
CCCCCEEEECCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10220347; 10913293; 11087383; 10368302 [H]