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The map label for this gene is phzA [H]

Identifier: 238024337

GI number: 238024337

Start: 1144910

End: 1145533

Strand: Direct

Name: phzA [H]

Synonym: bglu_2g09250

Alternate gene names: 238024337

Gene position: 1144910-1145533 (Clockwise)

Preceding gene: 238024336

Following gene: 238024338

Centisome position: 40.49

GC content: 62.82

Gene sequence:

>624_bases
ATGGCTGGTATCCCGTCGATTCAACCGTACGCGCTGCCCGATTCGAGCAGCCTGCCCGAGAATGTCGTGTCATGGCGTGT
CGACCCGTCGCGCGCGCTGCTGCTCATCCATGACATGCAGAACTATTTCCTTTCGCCGTTGCCGCCGACGCTGCGCGAGA
CGCTGACGACCAATGTCGCGTCGCTGCGCAAACGGTGCAAGCAGGCCGGTATTCCCGTCGCGTACACGGCCCATCCCGGA
CGCATGACCGAGAAGGAACGCGGTTTGTTACGCGATTTTTGGGGCCCGGGCATGGAGACGACGCCGGCCGATCGGGACGT
CGCGGAGGCTGTCGGCCCGTCTCCGGACGACTGGATGCTCACGAAGTGGCGCTACAGCGCATTTTTCCGCACCGACCTGC
GCGAGCGCATGCGGGAGAACGGTCGCGATCAGCTGATGTTGTGTGGCGTCTACGCGCACATCGGCGTAATGATGTCGGCC
GTCGATGCGTTCACGAACGACATTCAACCGTTCTTCGTCGCCGATGGCGTGGCGGATTTTTCCGAAGACCACCATCACCA
GGCCCTGGAATACGTAGCCACGCGTTGCGGCAAGGTGGTGAGCACCGAGGAGGCGCTGGCATGA

Upstream 100 bases:

>100_bases
TCATGAACCCTTGCGAGCAATTCCGTTCGTTGGGTATCGAGGTTCCCGAAGTGCGCCGGGATGGCCTACCGAGCTGACGC
ATACTCAACGGAGGAGACAA

Downstream 100 bases:

>100_bases
ACGCTGATCCGAATCGCAACCTTTTCAACCGCATCCTCGACGGACAAGCGCCGTGCTTTGCGTTGATCGCACGTTCGACG
GGTAGCGCCGGGGAGCGCGC

Product: Isochorismatase

Products: NA

Alternate protein names: 2,3 dihydro-2,3 dihydroxybenzoate synthase [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MAGIPSIQPYALPDSSSLPENVVSWRVDPSRALLLIHDMQNYFLSPLPPTLRETLTTNVASLRKRCKQAGIPVAYTAHPG
RMTEKERGLLRDFWGPGMETTPADRDVAEAVGPSPDDWMLTKWRYSAFFRTDLRERMRENGRDQLMLCGVYAHIGVMMSA
VDAFTNDIQPFFVADGVADFSEDHHHQALEYVATRCGKVVSTEEALA

Sequences:

>Translated_207_residues
MAGIPSIQPYALPDSSSLPENVVSWRVDPSRALLLIHDMQNYFLSPLPPTLRETLTTNVASLRKRCKQAGIPVAYTAHPG
RMTEKERGLLRDFWGPGMETTPADRDVAEAVGPSPDDWMLTKWRYSAFFRTDLRERMRENGRDQLMLCGVYAHIGVMMSA
VDAFTNDIQPFFVADGVADFSEDHHHQALEYVATRCGKVVSTEEALA
>Mature_206_residues
AGIPSIQPYALPDSSSLPENVVSWRVDPSRALLLIHDMQNYFLSPLPPTLRETLTTNVASLRKRCKQAGIPVAYTAHPGR
MTEKERGLLRDFWGPGMETTPADRDVAEAVGPSPDDWMLTKWRYSAFFRTDLRERMRENGRDQLMLCGVYAHIGVMMSAV
DAFTNDIQPFFVADGVADFSEDHHHQALEYVATRCGKVVSTEEALA

Specific function: Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. This isochorismatase may remove pyruvate from chorismate during the formation of

COG id: COG1535

COG function: function code Q; Isochorismate hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismatase family [H]

Homologues:

Organism=Escherichia coli, GI1786811, Length=206, Percent_Identity=50.9708737864078, Blast_Score=223, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016291
- InterPro:   IPR000868 [H]

Pfam domain/function: PF00857 Isochorismatase [H]

EC number: =3.3.2.1 [H]

Molecular weight: Translated: 23200; Mature: 23068

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGIPSIQPYALPDSSSLPENVVSWRVDPSRALLLIHDMQNYFLSPLPPTLRETLTTNVA
CCCCCCCCCCCCCCCCCCCHHHHHEEECCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHH
SLRKRCKQAGIPVAYTAHPGRMTEKERGLLRDFWGPGMETTPADRDVAEAVGPSPDDWML
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEE
TKWRYSAFFRTDLRERMRENGRDQLMLCGVYAHIGVMMSAVDAFTNDIQPFFVADGVADF
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
SEDHHHQALEYVATRCGKVVSTEEALA
HHHHHHHHHHHHHHHHCCHHCHHHHCC
>Mature Secondary Structure 
AGIPSIQPYALPDSSSLPENVVSWRVDPSRALLLIHDMQNYFLSPLPPTLRETLTTNVA
CCCCCCCCCCCCCCCCCCHHHHHEEECCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHH
SLRKRCKQAGIPVAYTAHPGRMTEKERGLLRDFWGPGMETTPADRDVAEAVGPSPDDWML
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCEE
TKWRYSAFFRTDLRERMRENGRDQLMLCGVYAHIGVMMSAVDAFTNDIQPFFVADGVADF
HHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
SEDHHHQALEYVATRCGKVVSTEEALA
HHHHHHHHHHHHHHHHCCHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8586283 [H]