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The map label for this gene is yiaY [H]

Identifier: 238024130

GI number: 238024130

Start: 832247

End: 833419

Strand: Reverse

Name: yiaY [H]

Synonym: bglu_2g07050

Alternate gene names: 238024130

Gene position: 833419-832247 (Counterclockwise)

Preceding gene: 238024131

Following gene: 238024129

Centisome position: 29.48

GC content: 68.63

Gene sequence:

>1173_bases
ATGAGCTACCTGAGCATCGCCGACCGCACCGACAGCTTCTTCATTCCCTGCGTCACGCTGATCGGCGCCGGCTGCGCGCG
CGAGACGGGCACGCGGGCGAAGTCGCTGGGCGCGAAAAAGGCGCTGATCGTCACCGACGCGGGACTGCACAAGATGGGCC
TGTCCGCGACGATCGCCGGCTATCTGCGCGAGGCCGGCGTCGACGCCGTGATCTTCCCCGGCGCCGAGCCGAACCCGACC
GACGTCAACGTGCACGACGGCGTGAAGCTCTATCAGCAAAACGGCTGTGATTTCATCGTGTCGCTGGGCGGCGGCTCCTC
GCACGACTGCGCGAAGGGCATCGGGCTCGTCACGGCGGGCGGCGGCCACATCAGCCACTACGAGGGCGTGGACAAATCGA
GCGTGCCGATGACGCCGCTCATCTCGATCAACACCACGGCCGGCACGGCCGCCGAGATGACGCGCTTTTGCATCATCACC
AACTCGAGCAACCACGTGAAGATGGCGATCGTCGACTGGCGCTGCACGCCGCTCATCGCGATCGACGACCCGCGCCTGAT
GGTGGCCATGCCGCCCGCGCTGACGGCCGCCACCGGCATGGACGCGCTCACGCACGCGGTGGAAGCCTACGTCTCCACCG
CCGCCACGCCGATCACCGACGCCTGCGCGGAAAAGGCGATCGCGCTGATCGGCGAGTGGCTGCCGAAGGCGGTGGCCAAC
GGCGAATCGATGGAGGCGCGCGCGGCCATGTGCTACGCGCAGTATCTGGCCGGCATGGCCTTCAACAACGCCTCGCTCGG
CTACGTCCATGCCATGGCGCACCAGCTCGGCGGCTTCTACAACCTGCCGCACGGCGTCTGCAACGCGATCCTGCTGCCGC
ACGTCTGCGAGTTCAACCTGATCGCGGCGCCGGAGCGCTTCGCGCGCATCGCCGCGCTGCTCGGCGCGAACACCGCGGGG
CTGTCGGTGACCGACGCGGGCGCCGCGGCGATCGCCGCGATCCGCGCGCTATCGGCCTCGATCGACATTCCCGCTGGCCT
CGCCGGCCTGGGCGTGAAGGCCGACGACCACGAGGTGATGGCGCGCAACGCGCAGAAGGATGCCTGCATGCTGACCAACC
CGCGCACGGCCACGCTGAAGCAGGTGATCGGCATCTTCGAAGCCGCGATGTAG

Upstream 100 bases:

>100_bases
CGGCGGGCCTTGGCGCAACGTGCGCTCCGGCGATGGTACGGTTCCTGCAAAGGACCGATGTGGCAGCAACGACACCCCCA
CATCATCATCCGGAGCAAAC

Downstream 100 bases:

>100_bases
GCGCCGCCGGCATGCCGCGGCCGGCACCAGCGGGCCGCCGCGCGCACCGTGGCCGGAAACGCGACGGCCCTGGGACGTTG
CGGGACGGCGCGATATCCTG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSYLSIADRTDSFFIPCVTLIGAGCARETGTRAKSLGAKKALIVTDAGLHKMGLSATIAGYLREAGVDAVIFPGAEPNPT
DVNVHDGVKLYQQNGCDFIVSLGGGSSHDCAKGIGLVTAGGGHISHYEGVDKSSVPMTPLISINTTAGTAAEMTRFCIIT
NSSNHVKMAIVDWRCTPLIAIDDPRLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVAN
GESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFARIAALLGANTAG
LSVTDAGAAAIAAIRALSASIDIPAGLAGLGVKADDHEVMARNAQKDACMLTNPRTATLKQVIGIFEAAM

Sequences:

>Translated_390_residues
MSYLSIADRTDSFFIPCVTLIGAGCARETGTRAKSLGAKKALIVTDAGLHKMGLSATIAGYLREAGVDAVIFPGAEPNPT
DVNVHDGVKLYQQNGCDFIVSLGGGSSHDCAKGIGLVTAGGGHISHYEGVDKSSVPMTPLISINTTAGTAAEMTRFCIIT
NSSNHVKMAIVDWRCTPLIAIDDPRLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVAN
GESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFARIAALLGANTAG
LSVTDAGAAAIAAIRALSASIDIPAGLAGLGVKADDHEVMARNAQKDACMLTNPRTATLKQVIGIFEAAM
>Mature_389_residues
SYLSIADRTDSFFIPCVTLIGAGCARETGTRAKSLGAKKALIVTDAGLHKMGLSATIAGYLREAGVDAVIFPGAEPNPTD
VNVHDGVKLYQQNGCDFIVSLGGGSSHDCAKGIGLVTAGGGHISHYEGVDKSSVPMTPLISINTTAGTAAEMTRFCIITN
SSNHVKMAIVDWRCTPLIAIDDPRLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVANG
ESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNLIAAPERFARIAALLGANTAGL
SVTDAGAAAIAAIRALSASIDIPAGLAGLGVKADDHEVMARNAQKDACMLTNPRTATLKQVIGIFEAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=27.8728606356968, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=57.7836411609499, Blast_Score=443, Evalue=1e-126,
Organism=Escherichia coli, GI1789163, Length=371, Percent_Identity=40.1617250673854, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI87082107, Length=384, Percent_Identity=37.7604166666667, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787493, Length=383, Percent_Identity=32.8981723237598, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789386, Length=359, Percent_Identity=26.1838440111421, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17537053, Length=421, Percent_Identity=23.5154394299287, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=51.1873350923483, Blast_Score=384, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24657991, Length=409, Percent_Identity=25.6723716381418, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40328; Mature: 40197

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLSIADRTDSFFIPCVTLIGAGCARETGTRAKSLGAKKALIVTDAGLHKMGLSATIAG
CCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCHHHHCCCCEEEEEECCCCHHHCHHHHHHH
YLREAGVDAVIFPGAEPNPTDVNVHDGVKLYQQNGCDFIVSLGGGSSHDCAKGIGLVTAG
HHHHCCCCEEEECCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCCCHHCCCEEEEEC
GGHISHYEGVDKSSVPMTPLISINTTAGTAAEMTRFCIITNSSNHVKMAIVDWRCTPLIA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEECCCEEEE
IDDPRLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVAN
ECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNL
CCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCE
IAAPERFARIAALLGANTAGLSVTDAGAAAIAAIRALSASIDIPAGLAGLGVKADDHEVM
EECHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
ARNAQKDACMLTNPRTATLKQVIGIFEAAM
HHCCCCCEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYLSIADRTDSFFIPCVTLIGAGCARETGTRAKSLGAKKALIVTDAGLHKMGLSATIAG
CCCCCCCCCCCCHHHHHHHHCCCCCHHCCCHHHHCCCCEEEEEECCCCHHHCHHHHHHH
YLREAGVDAVIFPGAEPNPTDVNVHDGVKLYQQNGCDFIVSLGGGSSHDCAKGIGLVTAG
HHHHCCCCEEEECCCCCCCCEEECCCCCCEEECCCCEEEEECCCCCCCCHHCCCEEEEEC
GGHISHYEGVDKSSVPMTPLISINTTAGTAAEMTRFCIITNSSNHVKMAIVDWRCTPLIA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEEECCCEEEE
IDDPRLMVAMPPALTAATGMDALTHAVEAYVSTAATPITDACAEKAIALIGEWLPKAVAN
ECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GESMEARAAMCYAQYLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAILLPHVCEFNL
CCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCE
IAAPERFARIAALLGANTAGLSVTDAGAAAIAAIRALSASIDIPAGLAGLGVKADDHEVM
EECHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
ARNAQKDACMLTNPRTATLKQVIGIFEAAM
HHCCCCCEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]