Click here to switch to the map view.

The map label for this gene is etfA [H]

Identifier: 238024033

GI number: 238024033

Start: 706313

End: 707488

Strand: Direct

Name: etfA [H]

Synonym: bglu_2g05870

Alternate gene names: 238024033

Gene position: 706313-707488 (Clockwise)

Preceding gene: 238024032

Following gene: 238024034

Centisome position: 24.98

GC content: 74.57

Gene sequence:

>1176_bases
ATGAACCCGATCAAACGACTCGATCCGCGCCGGCCGTTCGTGGTCACGGCGGCCGGACTCAAGCGCATCACGCTCGGCGA
GACCGCCGCGGCGGGCGCCAATCTCGCGCGCTGGACCGGCCACGCCCACGGGCGCGAGGCGGCCAAGCCGCGGCGCACGC
TCGAGGCGGCCGACCAGGTGCTGCTGGTGGCGGCGCATCCCGAGCGCGGCGCGCTCGACGATCACGCGCGGCAGGCCGTG
GCCGCCGCGGCGCTGATCGCCGACGCGCGCACCGCCGTGGTGCTGCTGTCGTTCGGCGAGCTGAAGGACGACCCGGCCGC
GCTCGGCATCGACCGGCTCATCGAGCTGCGCGGCTTCGACCGCCGCGCGTTCGCGCCCGACGACGAACTTCACGCGCTGC
TCGGCTGTGCCGCCGCGCTCGCGCCGCGCCACGTGTTCCTGCCCGACAACGCCACCGGCGACGGCGACCTCGGCCGCCGC
TACGCCGCCGCGCTCGGCGCGAGCGTGGCCGCCAACGTGGTCGAGATCGATGCGCAGCACGTCGGCGTCTACGCCGACGC
GAAGCGCCAGTTCGCCACCCGCGCGCTGCCCGACGTGGTGCTGCTGGCGCCGAACGCGGTGGAGCCGAAGCTGCCGTTCG
TCGGCGCGGGCGAGCGGCTCGATCCGCCGTTCGCGCCCGACGCCGCGGGCCGGGCCGGCGGCGCCGGGCGCTATCGCGAT
CTCGGCGTGGAGGAGATCGACGCGGCGCAGGTCGCGCTCGAGGAGGCCGATTTCATCGTCTCGGCCGGCAACGGCGTGAC
CGATATCGGCGCGTTCGAGCGGCTGGCCGCCGCGTTCGGCGCCGCGATCGGCGCGAGCCGCGTGGCGGTGGACAACGGCC
ACTTCACGCGCGACAAGCAGGTGGGCGCGACCGGCAAGACCGTCGAGGCGAGCGTCTACATCGCCTTCGGCATCTCGGGC
GCGGTCCAGCATCTGCAGGGCATCAAGGACTGCCGGCACGTGATCGCCGTGAACCTCGACGCGAGCGCGCCGATCGCCAA
GCGCGCGAACCTGACCGTGGTGGGCGACGCGCAGGCGACCATCGCCGCGCTGATCGAACAAGTCAACGCCGCGCGCGCGG
CCCGCGGCCATGCCGACGAGCCGCGCGCACGGCATCTGGAAGGAGTGGCCGCATGA

Upstream 100 bases:

>100_bases
GGCTGCCCCAACTGCACCGCGATGCTTGAGGGCGTGGTGGGGCCGCGCCCCGACGTGCTCGACCTGGCCGAACTGGTCGC
CGCCTCGCTGGAGTGAATCG

Downstream 100 bases:

>100_bases
ACAGCTTCCGCAGGCCGTCGCGCATCGCCGTGCTGGTGTCGGTGGGCCGCCATCCCGTGAGCGGCGCGCCGCGCTACAGC
CGCAACGACGCGGCCGCGCT

Product: Electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNPIKRLDPRRPFVVTAAGLKRITLGETAAAGANLARWTGHAHGREAAKPRRTLEAADQVLLVAAHPERGALDDHARQAV
AAAALIADARTAVVLLSFGELKDDPAALGIDRLIELRGFDRRAFAPDDELHALLGCAAALAPRHVFLPDNATGDGDLGRR
YAAALGASVAANVVEIDAQHVGVYADAKRQFATRALPDVVLLAPNAVEPKLPFVGAGERLDPPFAPDAAGRAGGAGRYRD
LGVEEIDAAQVALEEADFIVSAGNGVTDIGAFERLAAAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISG
AVQHLQGIKDCRHVIAVNLDASAPIAKRANLTVVGDAQATIAALIEQVNAARAARGHADEPRARHLEGVAA

Sequences:

>Translated_391_residues
MNPIKRLDPRRPFVVTAAGLKRITLGETAAAGANLARWTGHAHGREAAKPRRTLEAADQVLLVAAHPERGALDDHARQAV
AAAALIADARTAVVLLSFGELKDDPAALGIDRLIELRGFDRRAFAPDDELHALLGCAAALAPRHVFLPDNATGDGDLGRR
YAAALGASVAANVVEIDAQHVGVYADAKRQFATRALPDVVLLAPNAVEPKLPFVGAGERLDPPFAPDAAGRAGGAGRYRD
LGVEEIDAAQVALEEADFIVSAGNGVTDIGAFERLAAAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISG
AVQHLQGIKDCRHVIAVNLDASAPIAKRANLTVVGDAQATIAALIEQVNAARAARGHADEPRARHLEGVAA
>Mature_391_residues
MNPIKRLDPRRPFVVTAAGLKRITLGETAAAGANLARWTGHAHGREAAKPRRTLEAADQVLLVAAHPERGALDDHARQAV
AAAALIADARTAVVLLSFGELKDDPAALGIDRLIELRGFDRRAFAPDDELHALLGCAAALAPRHVFLPDNATGDGDLGRR
YAAALGASVAANVVEIDAQHVGVYADAKRQFATRALPDVVLLAPNAVEPKLPFVGAGERLDPPFAPDAAGRAGGAGRYRD
LGVEEIDAAQVALEEADFIVSAGNGVTDIGAFERLAAAFGAAIGASRVAVDNGHFTRDKQVGATGKTVEASVYIAFGISG
AVQHLQGIKDCRHVIAVNLDASAPIAKRANLTVVGDAQATIAALIEQVNAARAARGHADEPRARHLEGVAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=117, Percent_Identity=43.5897435897436, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4503607, Length=117, Percent_Identity=43.5897435897436, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1787990, Length=126, Percent_Identity=32.5396825396825, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786226, Length=118, Percent_Identity=33.8983050847458, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17506929, Length=119, Percent_Identity=43.6974789915966, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6325261, Length=120, Percent_Identity=40.8333333333333, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136898, Length=107, Percent_Identity=48.5981308411215, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24652801, Length=107, Percent_Identity=48.5981308411215, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 40569; Mature: 40569

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPIKRLDPRRPFVVTAAGLKRITLGETAAAGANLARWTGHAHGREAAKPRRTLEAADQV
CCCCHHCCCCCCEEEEECCCEEEECCCHHHCCCCHHHHCCCCCCCHHCCHHHHHHHCCEE
LLVAAHPERGALDDHARQAVAAAALIADARTAVVLLSFGELKDDPAALGIDRLIELRGFD
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCC
RRAFAPDDELHALLGCAAALAPRHVFLPDNATGDGDLGRRYAAALGASVAANVVEIDAQH
CCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHH
VGVYADAKRQFATRALPDVVLLAPNAVEPKLPFVGAGERLDPPFAPDAAGRAGGAGRYRD
CCEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGVEEIDAAQVALEEADFIVSAGNGVTDIGAFERLAAAFGAAIGASRVAVDNGHFTRDKQ
CCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
VGATGKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDASAPIAKRANLTVVGDAQAT
CCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCHHCCCEEEEECCHHH
IAALIEQVNAARAARGHADEPRARHLEGVAA
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC
>Mature Secondary Structure
MNPIKRLDPRRPFVVTAAGLKRITLGETAAAGANLARWTGHAHGREAAKPRRTLEAADQV
CCCCHHCCCCCCEEEEECCCEEEECCCHHHCCCCHHHHCCCCCCCHHCCHHHHHHHCCEE
LLVAAHPERGALDDHARQAVAAAALIADARTAVVLLSFGELKDDPAALGIDRLIELRGFD
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCC
RRAFAPDDELHALLGCAAALAPRHVFLPDNATGDGDLGRRYAAALGASVAANVVEIDAQH
CCCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHEEECHHH
VGVYADAKRQFATRALPDVVLLAPNAVEPKLPFVGAGERLDPPFAPDAAGRAGGAGRYRD
CCEEHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LGVEEIDAAQVALEEADFIVSAGNGVTDIGAFERLAAAFGAAIGASRVAVDNGHFTRDKQ
CCCHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
VGATGKTVEASVYIAFGISGAVQHLQGIKDCRHVIAVNLDASAPIAKRANLTVVGDAQAT
CCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHEEEEECCCCCCCHHCCCEEEEECCHHH
IAALIEQVNAARAARGHADEPRARHLEGVAA
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]