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The map label for this gene is tsr [H]

Identifier: 238023975

GI number: 238023975

Start: 631588

End: 633225

Strand: Direct

Name: tsr [H]

Synonym: bglu_2g05250

Alternate gene names: 238023975

Gene position: 631588-633225 (Clockwise)

Preceding gene: 238023973

Following gene: 238023981

Centisome position: 22.34

GC content: 68.56

Gene sequence:

>1638_bases
ATGTTAAAAAATCTCTCGATTCGTCATTGTGTGAACGCGATCATCGGCCTGTTCAGCGGCGCGCTGATCGCCGGTGCCTT
GCTCGGCGTGCTGTCCCTGAACTCGGTAAACCACGAGCTCGAGCAGATGTACACGGTCGACACGCCGGCCGTGGCGAACC
TCGAAGGCAGCTCGAGCCAGCTGCTGCGCCTGCGCCTGACGCTGGCCACCTACGATTCGCTGACGAACATCGGCGACACC
GACGGCGCGCAGGCCGCGGTCAAGCGCGCCGATCAGTACCTCAAGCTGTCGAACGAGCGCTTTGCGGCGTATCTCGCGCA
GGTCGGCGACGATCCCGCCGCGCGCGAGCTGATCGACGACATGCGGAACAAGCGCGACGACTTTCTCCACCAGGGGATCG
AGCCCGCGATGGCCGCGCTCAAGGCGGGCGACAAGGCCGGCTTCGGCGAACTGCAGGGCCACCGGCTCTCGCCGCTCTAT
TCGGCCTATGAAAAGGCGATGCTGGCGCTGGAGGACCGCCAGGTGGGCCTTGGCCGGACGCGCTACGAGGCGGCGCAGCA
CCGGTTCTCGATGGTCATCGCGGCGGTGGCGGTGGGCCTGGCGCTGTCGCTGGTGCTGGCGTGGTTCGCGCGGGCCTGGC
TCGTCGACGCGATCGTGAAGCCGGTGAATGCCGCCGTCGACAGTTTCGGCCGCATCGCCAAGGGCGACCTCACCGGCAAG
GTCGAGGTGGGCCGCCGCAACGAGATGGGCAAGCTCAGCGAGGCGCTGCTGACGATGCAGGAGTCGCTGATCGCGACGGT
GGGCGTGGTGCGGGCCAGTACCGAATCGATCAAGCTCGGCGTGAGCGAGATCGCCAGCGGCAACACCAACCTGTCGCAAC
GCACCGAGGGGCAGGCGGCCTCGCTCGAAGAAACCGCGGCGAGCATCGAGCAACTGACCTCCACGGTCAAGCAGACCGCC
GACAACCTGCGCCAGGCCAGCTCGCTCGCCAACGGCGCCGCGAACCTCGCGGACGAAGGCGGCCGGCTCTCGCGCGACGT
GGGCGGCACCATGCAGGACATCGTCAACAACGCACGCCGCATCGGCGACATCGTCGGCGTGATCGAGGGCATCGCGTTCC
AGACCAACATCCTCGCGCTGAACGCGGCGGTGGAGGCGGCGCGTGCGGGCGAACAGGGGCGCGGCTTCGCGGTGGTGGCC
AGCGAGGTGCGTTCGCTGGCCCAGCGCAGCGCGACGGCGGCCAAGGAGATCAAGGGGGTGATCATGGAATCGACGCAGCG
CGTGGAGACGGGTGCCGAACTCGTCGAGCGCTCGGGCTCGACCATGAACCAGATCGTCACCGCGATCGGCCGCGTGAGCG
GGATCATGAACGAGATCGCCGTGGCCTCGAGCGAGCAGAGCAACGGCATCGACCAGATCAACATCGCGATCGCGCAGATG
GACGAGGTCACGCAGCAGAACGCGGCGCTCGTCGAGCAGGCCGCAGCGGCGGCCGCCTCGCTGGTGGATCAGACGCAGCG
CCTGAGCGACGCGGTGGCGGTGTTTCGCGTCGGGCCGCAGGGCCGCGCGACGTTCGGCGGGCAGGCGGGGGGCGCGTTGG
TGCCGGTCGCAATCGGCGCACTGCAGCCCGCGTGCTGA

Upstream 100 bases:

>100_bases
ACTTGGAGACGGCGGCGCGTATGTCAAAACATTACGTCCAAATCATGAGAATCGCGCGGGACAGGCACTTGGGTTTCGCT
CGAATCACCGATCAAAACAC

Downstream 100 bases:

>100_bases
GCGGACCCGCCGGTCGCACGCGTGAAGACCGCCGGCGGCTCGTCGATGACCCGAAACCCGTTCGTCGAACCGCCGGGCCT
GCGGCAAACGTATCCGAGCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MLKNLSIRHCVNAIIGLFSGALIAGALLGVLSLNSVNHELEQMYTVDTPAVANLEGSSSQLLRLRLTLATYDSLTNIGDT
DGAQAAVKRADQYLKLSNERFAAYLAQVGDDPAARELIDDMRNKRDDFLHQGIEPAMAALKAGDKAGFGELQGHRLSPLY
SAYEKAMLALEDRQVGLGRTRYEAAQHRFSMVIAAVAVGLALSLVLAWFARAWLVDAIVKPVNAAVDSFGRIAKGDLTGK
VEVGRRNEMGKLSEALLTMQESLIATVGVVRASTESIKLGVSEIASGNTNLSQRTEGQAASLEETAASIEQLTSTVKQTA
DNLRQASSLANGAANLADEGGRLSRDVGGTMQDIVNNARRIGDIVGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRSLAQRSATAAKEIKGVIMESTQRVETGAELVERSGSTMNQIVTAIGRVSGIMNEIAVASSEQSNGIDQINIAIAQM
DEVTQQNAALVEQAAAAAASLVDQTQRLSDAVAVFRVGPQGRATFGGQAGGALVPVAIGALQPAC

Sequences:

>Translated_545_residues
MLKNLSIRHCVNAIIGLFSGALIAGALLGVLSLNSVNHELEQMYTVDTPAVANLEGSSSQLLRLRLTLATYDSLTNIGDT
DGAQAAVKRADQYLKLSNERFAAYLAQVGDDPAARELIDDMRNKRDDFLHQGIEPAMAALKAGDKAGFGELQGHRLSPLY
SAYEKAMLALEDRQVGLGRTRYEAAQHRFSMVIAAVAVGLALSLVLAWFARAWLVDAIVKPVNAAVDSFGRIAKGDLTGK
VEVGRRNEMGKLSEALLTMQESLIATVGVVRASTESIKLGVSEIASGNTNLSQRTEGQAASLEETAASIEQLTSTVKQTA
DNLRQASSLANGAANLADEGGRLSRDVGGTMQDIVNNARRIGDIVGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRSLAQRSATAAKEIKGVIMESTQRVETGAELVERSGSTMNQIVTAIGRVSGIMNEIAVASSEQSNGIDQINIAIAQM
DEVTQQNAALVEQAAAAAASLVDQTQRLSDAVAVFRVGPQGRATFGGQAGGALVPVAIGALQPAC
>Mature_545_residues
MLKNLSIRHCVNAIIGLFSGALIAGALLGVLSLNSVNHELEQMYTVDTPAVANLEGSSSQLLRLRLTLATYDSLTNIGDT
DGAQAAVKRADQYLKLSNERFAAYLAQVGDDPAARELIDDMRNKRDDFLHQGIEPAMAALKAGDKAGFGELQGHRLSPLY
SAYEKAMLALEDRQVGLGRTRYEAAQHRFSMVIAAVAVGLALSLVLAWFARAWLVDAIVKPVNAAVDSFGRIAKGDLTGK
VEVGRRNEMGKLSEALLTMQESLIATVGVVRASTESIKLGVSEIASGNTNLSQRTEGQAASLEETAASIEQLTSTVKQTA
DNLRQASSLANGAANLADEGGRLSRDVGGTMQDIVNNARRIGDIVGVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVA
SEVRSLAQRSATAAKEIKGVIMESTQRVETGAELVERSGSTMNQIVTAIGRVSGIMNEIAVASSEQSNGIDQINIAIAQM
DEVTQQNAALVEQAAAAAASLVDQTQRLSDAVAVFRVGPQGRATFGGQAGGALVPVAIGALQPAC

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=546, Percent_Identity=45.4212454212454, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1787690, Length=494, Percent_Identity=42.5101214574899, Blast_Score=320, Evalue=2e-88,
Organism=Escherichia coli, GI1788195, Length=301, Percent_Identity=56.8106312292359, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1788194, Length=325, Percent_Identity=53.2307692307692, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1789453, Length=324, Percent_Identity=35.8024691358025, Blast_Score=186, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57164; Mature: 57164

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]