Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 238023894

GI number: 238023894

Start: 522268

End: 522825

Strand: Reverse

Name: sigW [H]

Synonym: bglu_2g04330

Alternate gene names: 238023894

Gene position: 522825-522268 (Counterclockwise)

Preceding gene: 238023895

Following gene: 238023893

Centisome position: 18.49

GC content: 71.15

Gene sequence:

>558_bases
GTGCTCTTCAAGACCGACCCGGACGCCTCGCTGATCGGGCGAATCGCGCAGGGCGACGACAAGGCGGCAGCCGCACTGGT
GTCACGCAAGCTGCATCGCATCGTCGCGCTCGCCTATCGCCTGCTCGGCGACGTGGCGGAAGCCGAGGACGTCGCGCAGG
AGGTGTTCGTGCGCGTGTGGAAGTACGCGCGCTCGTGGCGCGAGGAGCGTGCGCGGGTCGACACCTGGCTGCATCGCATC
GCGCTGAACGTCTGCCACGACCGGCTCGAGCTGCGCGCGCGCCGCCGCGAGACGGACGCGCTCGACCCCGACCTGCAGGC
CGATGCCGGCCCGACGCCGGAGGCGCAGTGGCTCGCGAAATCGATGCGCGAACGCGTGCGGGAGGCCCTGGCCGCGCTGC
CCGTGCGCCAGCGCGAGGCGCTGGTGCTGACCTACTACCAGGAACTGAGCAATGCCGAGGCGGCCACGGCGATGGCGCTC
AGCGTCGAGGCGATCGAAAGCCTGCTGGCGCGGGCCCGCAAAGCGCTGCGCCAGCGCCTGCAAGATATCCACGGATGA

Upstream 100 bases:

>100_bases
GGTCGGTTATCACTGGCAGCCGGGCCACTGGGCACCGCGCGGCGACGGCTGGGTCTGGATTCGCGGCCACTGGGTTGCGT
GAGCCTTCCCGTCCGCTCGC

Downstream 100 bases:

>100_bases
AGGAGCCCGCACCATGACTGCCGACCAATTTCGCGATCTGATCGACCGGCACGGCGCGAACCCGCGGCGCTGGCCGGCGC
CGTGCCGTGAAGCCGCCTGG

Product: ECF subfamily RNA polymerase sigma-24 subunit

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLFKTDPDASLIGRIAQGDDKAAAALVSRKLHRIVALAYRLLGDVAEAEDVAQEVFVRVWKYARSWREERARVDTWLHRI
ALNVCHDRLELRARRRETDALDPDLQADAGPTPEAQWLAKSMRERVREALAALPVRQREALVLTYYQELSNAEAATAMAL
SVEAIESLLARARKALRQRLQDIHG

Sequences:

>Translated_185_residues
MLFKTDPDASLIGRIAQGDDKAAAALVSRKLHRIVALAYRLLGDVAEAEDVAQEVFVRVWKYARSWREERARVDTWLHRI
ALNVCHDRLELRARRRETDALDPDLQADAGPTPEAQWLAKSMRERVREALAALPVRQREALVLTYYQELSNAEAATAMAL
SVEAIESLLARARKALRQRLQDIHG
>Mature_185_residues
MLFKTDPDASLIGRIAQGDDKAAAALVSRKLHRIVALAYRLLGDVAEAEDVAQEVFVRVWKYARSWREERARVDTWLHRI
ALNVCHDRLELRARRRETDALDPDLQADAGPTPEAQWLAKSMRERVREALAALPVRQREALVLTYYQELSNAEAATAMAL
SVEAIESLLARARKALRQRLQDIHG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=186, Percent_Identity=31.7204301075269, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 20975; Mature: 20975

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFKTDPDASLIGRIAQGDDKAAAALVSRKLHRIVALAYRLLGDVAEAEDVAQEVFVRVW
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYARSWREERARVDTWLHRIALNVCHDRLELRARRRETDALDPDLQADAGPTPEAQWLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
SMRERVREALAALPVRQREALVLTYYQELSNAEAATAMALSVEAIESLLARARKALRQRL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDIHG
HHHCC
>Mature Secondary Structure
MLFKTDPDASLIGRIAQGDDKAAAALVSRKLHRIVALAYRLLGDVAEAEDVAQEVFVRVW
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYARSWREERARVDTWLHRIALNVCHDRLELRARRRETDALDPDLQADAGPTPEAQWLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
SMRERVREALAALPVRQREALVLTYYQELSNAEAATAMALSVEAIESLLARARKALRQRL
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDIHG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]