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The map label for this gene is exuT [H]

Identifier: 238023886

GI number: 238023886

Start: 509861

End: 511168

Strand: Direct

Name: exuT [H]

Synonym: bglu_2g04250

Alternate gene names: 238023886

Gene position: 509861-511168 (Clockwise)

Preceding gene: 238023885

Following gene: 238023887

Centisome position: 18.03

GC content: 65.52

Gene sequence:

>1308_bases
ATGAAGGAGAAGGACTTGAAAACCATAGCTGGCCTGCGCTGGTGGATCATTGCCCTCGTGTGCCTGGGGACCATCGTCAA
CTACCTGTCGCGCAACGCGCTGGGGGTGCTCGCGCCGCAGCTCAAGACGCTCCTGAGCATGAGCACGCAGCAGTACTCCT
ACGTGGTGGGGGCATTTCAGGTCGGCTACACGCTGATGCAGCCGGTATGCGGGCTCGTCATCGACATCATCGGACTGCGC
GCGGGCTTTGCGATCTTCGCCATGCTGTGGTCGGCCGTCGGCTGCCTGCACGGCCTGGCGAGCGGCTGGGCATCGCTTGC
CGCGCTGCGCGGGCTGATGGGGCTCACGGAGGCGGTGGCGATTCCCGCCGGGATGAAGGTGGTCGCCGAATGGTTCCCGA
ACAAGGAACGCTCGGTGGCCGTGGGCTATTTCAACGCCGGCACCTCGCTCGGTTCGCTGCTCGCCCCGCCGCTGGTGATC
TTCATCTCCTTGCGGTACGGATGGCAGGCCGCGTTTGCCGTCACTGGCGCGCTCGGCTTCGCGTGGGCGGCAATCTGGTA
CGTCTTTTATCGTTCTCCTGACAATCACCGGAAGATATCGGCCAAGGAGTATGAAAAGATCGTGGCCGGAAAGGAGCCGA
GCGGGTCCGCCGCCGGCGGCCGGCGCCGTGTGCGCGACGTGATCGCGACGCGACGCTTCTGGGCCATCGCGCAGGCGCGC
TTCTTCGCCGAGCCGGCCTGGCAGACGTTCAGCTTCTGGATTCCGCTCTACCTGGCAACCGAGCGCCACATGGATTTGAA
GCAAATCGCCATTTTTGCCTGGCTGCCGTTTCTCGCGGCCGATCTGGGCGGCCTGTTCGGCGGCTACCTGTCTCCGTTCC
TGATCAAGTATCTGCGCATCCCGCTGATCTGGTCGCGCGTCGCCGGCGTCGTGCTCGGCGCGTTCATGATGATCGGCCCC
GCCTGCATCGGATTCGTCGCTTCGCCTTACGAGGCCATCGCGCTCTTCTGCGTGGGCGGCTTCGCCCATCAGATGATCTC
GGCCCTGGTCAACACGCTGTCGGCCGATGTTTTCGATTCCAGCGAAGTCGGCACGGCGAGCGGCTTCGCCGGCATGGCCG
CGTGGATCGGCGGACTCGGTTTTTCGCTGCTGGTGGGCGCGCTTGCCGATTCCATCGGCTACAAGCCGCTGTTCGTGGCA
CTCGGCGCGTTCGATCTGATCGGCGCGACGCTCCTGATCATCCTGATGCGCGGCGTGACTCGCCCGCGCCCGGACGCGGC
GACGCGCGGCACGCGCCCCGCCGCTTAA

Upstream 100 bases:

>100_bases
GGGCATTTCCAAGTGGTACGATGACTGCCGTGATGGTTCGAATGCGTACCGAATCGAACATAACTCGAAAATTCCGACCG
ATGCGATCGGGTCTGGAGAC

Downstream 100 bases:

>100_bases
CGTCGATCAACCTCAGTCAAAGGCTGGACATGGCATCACTCAACAACCGTCCCCGCTTCGCGCTTGCCACCCGGTCGGGC
GCGCATCTGGTGCTGGGCGC

Product: major facilitator superfamily protein

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKEKDLKTIAGLRWWIIALVCLGTIVNYLSRNALGVLAPQLKTLLSMSTQQYSYVVGAFQVGYTLMQPVCGLVIDIIGLR
AGFAIFAMLWSAVGCLHGLASGWASLAALRGLMGLTEAVAIPAGMKVVAEWFPNKERSVAVGYFNAGTSLGSLLAPPLVI
FISLRYGWQAAFAVTGALGFAWAAIWYVFYRSPDNHRKISAKEYEKIVAGKEPSGSAAGGRRRVRDVIATRRFWAIAQAR
FFAEPAWQTFSFWIPLYLATERHMDLKQIAIFAWLPFLAADLGGLFGGYLSPFLIKYLRIPLIWSRVAGVVLGAFMMIGP
ACIGFVASPYEAIALFCVGGFAHQMISALVNTLSADVFDSSEVGTASGFAGMAAWIGGLGFSLLVGALADSIGYKPLFVA
LGAFDLIGATLLIILMRGVTRPRPDAATRGTRPAA

Sequences:

>Translated_435_residues
MKEKDLKTIAGLRWWIIALVCLGTIVNYLSRNALGVLAPQLKTLLSMSTQQYSYVVGAFQVGYTLMQPVCGLVIDIIGLR
AGFAIFAMLWSAVGCLHGLASGWASLAALRGLMGLTEAVAIPAGMKVVAEWFPNKERSVAVGYFNAGTSLGSLLAPPLVI
FISLRYGWQAAFAVTGALGFAWAAIWYVFYRSPDNHRKISAKEYEKIVAGKEPSGSAAGGRRRVRDVIATRRFWAIAQAR
FFAEPAWQTFSFWIPLYLATERHMDLKQIAIFAWLPFLAADLGGLFGGYLSPFLIKYLRIPLIWSRVAGVVLGAFMMIGP
ACIGFVASPYEAIALFCVGGFAHQMISALVNTLSADVFDSSEVGTASGFAGMAAWIGGLGFSLLVGALADSIGYKPLFVA
LGAFDLIGATLLIILMRGVTRPRPDAATRGTRPAA
>Mature_435_residues
MKEKDLKTIAGLRWWIIALVCLGTIVNYLSRNALGVLAPQLKTLLSMSTQQYSYVVGAFQVGYTLMQPVCGLVIDIIGLR
AGFAIFAMLWSAVGCLHGLASGWASLAALRGLMGLTEAVAIPAGMKVVAEWFPNKERSVAVGYFNAGTSLGSLLAPPLVI
FISLRYGWQAAFAVTGALGFAWAAIWYVFYRSPDNHRKISAKEYEKIVAGKEPSGSAAGGRRRVRDVIATRRFWAIAQAR
FFAEPAWQTFSFWIPLYLATERHMDLKQIAIFAWLPFLAADLGGLFGGYLSPFLIKYLRIPLIWSRVAGVVLGAFMMIGP
ACIGFVASPYEAIALFCVGGFAHQMISALVNTLSADVFDSSEVGTASGFAGMAAWIGGLGFSLLVGALADSIGYKPLFVA
LGAFDLIGATLLIILMRGVTRPRPDAATRGTRPAA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI148743791, Length=319, Percent_Identity=25.0783699059561, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI6912666, Length=385, Percent_Identity=25.1948051948052, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI154800443, Length=337, Percent_Identity=24.0356083086053, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI148728191, Length=295, Percent_Identity=25.7627118644068, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4885441, Length=203, Percent_Identity=27.0935960591133, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI5031955, Length=199, Percent_Identity=25.6281407035176, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI2367193, Length=431, Percent_Identity=46.4037122969838, Blast_Score=401, Evalue=1e-113,
Organism=Escherichia coli, GI87082320, Length=417, Percent_Identity=27.3381294964029, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1789515, Length=331, Percent_Identity=28.7009063444109, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI2367379, Length=433, Percent_Identity=27.9445727482679, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789152, Length=429, Percent_Identity=24.009324009324, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17560030, Length=288, Percent_Identity=24.3055555555556, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=245, Percent_Identity=27.7551020408163, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536337, Length=198, Percent_Identity=26.7676767676768, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI20129235, Length=404, Percent_Identity=26.980198019802, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573708, Length=219, Percent_Identity=29.2237442922374, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573707, Length=219, Percent_Identity=29.2237442922374, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573299, Length=431, Percent_Identity=22.969837587007, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20130135, Length=415, Percent_Identity=23.855421686747, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24655271, Length=415, Percent_Identity=23.855421686747, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24641682, Length=289, Percent_Identity=25.2595155709343, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648416, Length=266, Percent_Identity=26.6917293233083, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356189, Length=266, Percent_Identity=26.6917293233083, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45550460, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920686, Length=294, Percent_Identity=25.8503401360544, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24655255, Length=358, Percent_Identity=25.1396648044693, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24580790, Length=309, Percent_Identity=25.8899676375405, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550364, Length=298, Percent_Identity=23.1543624161074, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658674, Length=249, Percent_Identity=28.1124497991968, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24658658, Length=470, Percent_Identity=22.7659574468085, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922400, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24639764, Length=251, Percent_Identity=23.9043824701195, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24654215, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46787; Mature: 46787

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]