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The map label for this gene is dmsA [H]

Identifier: 238023664

GI number: 238023664

Start: 209272

End: 211794

Strand: Reverse

Name: dmsA [H]

Synonym: bglu_2g01850

Alternate gene names: 238023664

Gene position: 211794-209272 (Counterclockwise)

Preceding gene: 238023665

Following gene: 238023661

Centisome position: 7.49

GC content: 67.18

Gene sequence:

>2523_bases
ATGTCTGCCGTCACGCCCAAGCCTCACCCGACTCTCGACCGGCGCGCCTTCATCAAGAGCGCCTCCGCCCTGGCCGCGCT
CGGCGCGCTCGGTGTGTCGCCGTTCAGCCGCGGCGCGCAGGCAGCAGCGCCGGACCGCACGGTGCTGTCGGCCTGCCACT
GGGGCATCTTCCGCGCGCGCGTGCGCAACGGCCGCTTCGATCGGATCACACCGTGGGAGGGCGACCCGCACCCCACTCCG
ATGCTGCAAGGCGTGCGCGATTCCATCTATTCGCCGACCCGCATCAAATATCCGATGGTGCGCCGTGCCTGGCTCGAGCA
CGGCCCCGGCGCCGATCCGGACGGCCGCAGCACCGGAGACTTCGTGCGCGTGAGCTGGGAGCGGGCAATCGCGCTGGTGG
CCGGCGAACTCGACCGCGTGCGCAAGCATCATGGCAATACGGCGATCTACGCCGGCTCCTACGGCTGGAAAAGCACCGGC
AAGCTGCACAGCTGCCGCGTGCTGCTCTGGCGCATGCTCAAGCTGTACGGCGGCTTCACGAGTTCGCTGAGCAACTACTC
GGACGCCGCCACCTCGGCCGTGCTGCCCTACGTGGTGGGCTCGGCCGGCGTAGTCGATCAATGCACGACCTGGCCCGTGA
TCGCGAAGCACACGCAGGTGCTGGTGCTGTGGGGCTGCAACCCGTTCAACACCTGCCAGATCGGCTGGCTCGTTCCCGAT
CACAACTACTTCGACCTGATCAAGACGGCGAAGGCGGCCGGCATCAAGGTGATCTGCATCGACCCGATCCGCACCGAAAG
CTGCAAGCTGCTCGACGGCGAATGGATCGCGCCGCGCCCGCAGACCGATGTCGCGATGATGCTCGGCATCGCCCATACCC
TCTACAGCGAGAAGCTGCACGACGAGGCATTCCTGAAGCGCTATACCACCGGCTTCGACGCGTTTTTGGCCTACCTGACC
GGCCGCACCGACGGCACGCCGAAGACGCCGGAATGGGCCGCGGAGATCTGCGGCATCGAGCCCGCCAAGCTGCGCGAGCT
CGCCCGCACCTTCGCCACGCACCGCACCATGCTCGCGCTCGGCTGGTCGACGCAGCGCCAGCAGCACGGCGAGCAAGTGC
CGTGGATGCTCGTCACGCTCGCCGCGATGCTGGGCCAGATCGGCCTGCCCGGCGGCGGCTTCGGCCACGCCTACCACTAC
AACGCCGGAGTGCCCACCCACACCTCGCCGAGTCTTCCGGGCATGACCGACGGCAGCTCGGTCAAGGAACTCCGGCCCGG
CTGCTATCCGGGCAACACCTCGTCGTATTGCCTCGACGAACAGGGCCCGGCGATTCCGGTCGCACGCGTGGTGGAGATGC
TGCGCAACCCGGGCAAGACGATCGACTACAACGGCGGCAAGCTCACCTATCCGGACGTCAAGCTCGTCTACTGGGCGGGC
GGCAATCCGTTCGCGCACCATCAGGACCGCAACGAAATGGTGCAAGCCTGGAAGAAGGTCGAAACCTTCGTCGTCCACGA
CTTCCAGTGGACGGCCAGCGCCCGCCACGCCGACATCGTGCTGCCCGTCACCACCTCTTATGAGCGCAACGACATCGAGC
AGGTGGGCGACTTCGCGCTCAGCCACATCGTGCCGATGAAGAAGGTGATCGAGCCGCTCTACGAGGCGCGCTCCGACTAC
GACATCTTCGCGGACATCTGCGCAAAGATCGACCGGCGCGACGCGTTCACGGAAGGCCTGACCGAGATGGACTGGATCCG
CCGCTTCTACGAGAAAGGCCGGCTGGTGGCGCGCGCCAAGGGCATGGAGATGCCGGTGTTCGACGTGTTCTGGGAGAGCG
ACGCACCGCTTGCATTCCCGCTCGCCAAGGGGCCGACCGACTATGTCGCCTATGCGGACTTCCGCGCGGACCCGCTGCTC
AACGCGCTCGGCACCGCCTCGGGCAAGTTCGAGATCTATTCGAAGACGATCGAGAAGATGCACTACGACGACTGCCCGCC
GCATCCGACCTGGATCGAGCCGGTCGAGCGGCTCGGCGGCCCCACCGCGCGCTTCCCGCTGCACGTCGCGGCGATCCATC
CGAACTACCGGCTGCATTCGCAGCTGTGCGGCACGGCGCTGCGCGAGATCTATGCGGTGAGCGGGCGCGAGCCGTGCTGG
ATGAACCCGAAGGACGCGGCCGCGCGCGGCCTGAAAAACGGCGACATCGCGCGCGCCTACAACGACCGCGGCCAGATCCT
GGTCGGCATCCGGGTGACCGACGACATCATGCCCGGCGTGATTCGGATCAACGAGGGCGGCTGGTACGATCCGGCCGATC
CGCGCCGAGCGAACACGCTGTGCCGCTACGGCGATGTCAACGTGCTGACCACCAGCATCGCAACCTCGAAGCTCGCGCAG
GCGACCTCGGCGCAGACCGTGATCTGTGAAGTGGAGAAGTTCCACGGCCCGATCCCGCCGGTGCGTGTGTTCGACGAACC
GGACGCGCAGGCATCGCCCGCCGGGCGCAGCAGCAAGCGCTGA

Upstream 100 bases:

>100_bases
CGAGCTCGTCACGCTGCTGGACGCCTTTCTCTCATACCTGCCACCGGCCGCGACGATGCATGGCGCGCCGGGCGAGCGAC
CTTCCTTCTAGGAGTCTCCG

Downstream 100 bases:

>100_bases
ACGCCGCGCGGCGCACAAGCCCCCTGCCGTGCTGTCGGGCGGCATGGTGCAATGTGCCGCGACCGCGTCCGAGCTGACCG
ACAAGCCGGGACCGCTGCGA

Product: trimethylamine-N-oxide reductase

Products: NAD+; trimethylamine; H2O

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 840; Mature: 839

Protein sequence:

>840_residues
MSAVTPKPHPTLDRRAFIKSASALAALGALGVSPFSRGAQAAAPDRTVLSACHWGIFRARVRNGRFDRITPWEGDPHPTP
MLQGVRDSIYSPTRIKYPMVRRAWLEHGPGADPDGRSTGDFVRVSWERAIALVAGELDRVRKHHGNTAIYAGSYGWKSTG
KLHSCRVLLWRMLKLYGGFTSSLSNYSDAATSAVLPYVVGSAGVVDQCTTWPVIAKHTQVLVLWGCNPFNTCQIGWLVPD
HNYFDLIKTAKAAGIKVICIDPIRTESCKLLDGEWIAPRPQTDVAMMLGIAHTLYSEKLHDEAFLKRYTTGFDAFLAYLT
GRTDGTPKTPEWAAEICGIEPAKLRELARTFATHRTMLALGWSTQRQQHGEQVPWMLVTLAAMLGQIGLPGGGFGHAYHY
NAGVPTHTSPSLPGMTDGSSVKELRPGCYPGNTSSYCLDEQGPAIPVARVVEMLRNPGKTIDYNGGKLTYPDVKLVYWAG
GNPFAHHQDRNEMVQAWKKVETFVVHDFQWTASARHADIVLPVTTSYERNDIEQVGDFALSHIVPMKKVIEPLYEARSDY
DIFADICAKIDRRDAFTEGLTEMDWIRRFYEKGRLVARAKGMEMPVFDVFWESDAPLAFPLAKGPTDYVAYADFRADPLL
NALGTASGKFEIYSKTIEKMHYDDCPPHPTWIEPVERLGGPTARFPLHVAAIHPNYRLHSQLCGTALREIYAVSGREPCW
MNPKDAAARGLKNGDIARAYNDRGQILVGIRVTDDIMPGVIRINEGGWYDPADPRRANTLCRYGDVNVLTTSIATSKLAQ
ATSAQTVICEVEKFHGPIPPVRVFDEPDAQASPAGRSSKR

Sequences:

>Translated_840_residues
MSAVTPKPHPTLDRRAFIKSASALAALGALGVSPFSRGAQAAAPDRTVLSACHWGIFRARVRNGRFDRITPWEGDPHPTP
MLQGVRDSIYSPTRIKYPMVRRAWLEHGPGADPDGRSTGDFVRVSWERAIALVAGELDRVRKHHGNTAIYAGSYGWKSTG
KLHSCRVLLWRMLKLYGGFTSSLSNYSDAATSAVLPYVVGSAGVVDQCTTWPVIAKHTQVLVLWGCNPFNTCQIGWLVPD
HNYFDLIKTAKAAGIKVICIDPIRTESCKLLDGEWIAPRPQTDVAMMLGIAHTLYSEKLHDEAFLKRYTTGFDAFLAYLT
GRTDGTPKTPEWAAEICGIEPAKLRELARTFATHRTMLALGWSTQRQQHGEQVPWMLVTLAAMLGQIGLPGGGFGHAYHY
NAGVPTHTSPSLPGMTDGSSVKELRPGCYPGNTSSYCLDEQGPAIPVARVVEMLRNPGKTIDYNGGKLTYPDVKLVYWAG
GNPFAHHQDRNEMVQAWKKVETFVVHDFQWTASARHADIVLPVTTSYERNDIEQVGDFALSHIVPMKKVIEPLYEARSDY
DIFADICAKIDRRDAFTEGLTEMDWIRRFYEKGRLVARAKGMEMPVFDVFWESDAPLAFPLAKGPTDYVAYADFRADPLL
NALGTASGKFEIYSKTIEKMHYDDCPPHPTWIEPVERLGGPTARFPLHVAAIHPNYRLHSQLCGTALREIYAVSGREPCW
MNPKDAAARGLKNGDIARAYNDRGQILVGIRVTDDIMPGVIRINEGGWYDPADPRRANTLCRYGDVNVLTTSIATSKLAQ
ATSAQTVICEVEKFHGPIPPVRVFDEPDAQASPAGRSSKR
>Mature_839_residues
SAVTPKPHPTLDRRAFIKSASALAALGALGVSPFSRGAQAAAPDRTVLSACHWGIFRARVRNGRFDRITPWEGDPHPTPM
LQGVRDSIYSPTRIKYPMVRRAWLEHGPGADPDGRSTGDFVRVSWERAIALVAGELDRVRKHHGNTAIYAGSYGWKSTGK
LHSCRVLLWRMLKLYGGFTSSLSNYSDAATSAVLPYVVGSAGVVDQCTTWPVIAKHTQVLVLWGCNPFNTCQIGWLVPDH
NYFDLIKTAKAAGIKVICIDPIRTESCKLLDGEWIAPRPQTDVAMMLGIAHTLYSEKLHDEAFLKRYTTGFDAFLAYLTG
RTDGTPKTPEWAAEICGIEPAKLRELARTFATHRTMLALGWSTQRQQHGEQVPWMLVTLAAMLGQIGLPGGGFGHAYHYN
AGVPTHTSPSLPGMTDGSSVKELRPGCYPGNTSSYCLDEQGPAIPVARVVEMLRNPGKTIDYNGGKLTYPDVKLVYWAGG
NPFAHHQDRNEMVQAWKKVETFVVHDFQWTASARHADIVLPVTTSYERNDIEQVGDFALSHIVPMKKVIEPLYEARSDYD
IFADICAKIDRRDAFTEGLTEMDWIRRFYEKGRLVARAKGMEMPVFDVFWESDAPLAFPLAKGPTDYVAYADFRADPLLN
ALGTASGKFEIYSKTIEKMHYDDCPPHPTWIEPVERLGGPTARFPLHVAAIHPNYRLHSQLCGTALREIYAVSGREPCWM
NPKDAAARGLKNGDIARAYNDRGQILVGIRVTDDIMPGVIRINEGGWYDPADPRRANTLCRYGDVNVLTTSIATSKLAQA
TSAQTVICEVEKFHGPIPPVRVFDEPDAQASPAGRSSKR

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=827, Percent_Identity=45.223700120919, Blast_Score=737, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=834, Percent_Identity=43.5251798561151, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=792, Percent_Identity=44.1919191919192, Blast_Score=678, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=856, Percent_Identity=29.6728971962617, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1787870, Length=862, Percent_Identity=29.8143851508121, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI171474008, Length=873, Percent_Identity=27.262313860252, Blast_Score=252, Evalue=6e-68,
Organism=Escherichia coli, GI3868721, Length=527, Percent_Identity=22.5806451612903, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.6.6.9

Molecular weight: Translated: 92976; Mature: 92845

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVTPKPHPTLDRRAFIKSASALAALGALGVSPFSRGAQAAAPDRTVLSACHWGIFRAR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHH
VRNGRFDRITPWEGDPHPTPMLQGVRDSIYSPTRIKYPMVRRAWLEHGPGADPDGRSTGD
HHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
FVRVSWERAIALVAGELDRVRKHHGNTAIYAGSYGWKSTGKLHSCRVLLWRMLKLYGGFT
EEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHH
SSLSNYSDAATSAVLPYVVGSAGVVDQCTTWPVIAKHTQVLVLWGCNPFNTCQIGWLVPD
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEEECCC
HNYFDLIKTAKAAGIKVICIDPIRTESCKLLDGEWIAPRPQTDVAMMLGIAHTLYSEKLH
CCHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEAFLKRYTTGFDAFLAYLTGRTDGTPKTPEWAAEICGIEPAKLRELARTFATHRTMLAL
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEE
GWSTQRQQHGEQVPWMLVTLAAMLGQIGLPGGGFGHAYHYNAGVPTHTSPSLPGMTDGSS
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
VKELRPGCYPGNTSSYCLDEQGPAIPVARVVEMLRNPGKTIDYNGGKLTYPDVKLVYWAG
HHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEEC
GNPFAHHQDRNEMVQAWKKVETFVVHDFQWTASARHADIVLPVTTSYERNDIEQVGDFAL
CCCCCCCCCHHHHHHHHHHHHHHEEECEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHH
SHIVPMKKVIEPLYEARSDYDIFADICAKIDRRDAFTEGLTEMDWIRRFYEKGRLVARAK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEECC
GMEMPVFDVFWESDAPLAFPLAKGPTDYVAYADFRADPLLNALGTASGKFEIYSKTIEKM
CCCCCEEEEEECCCCCEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
HYDDCPPHPTWIEPVERLGGPTARFPLHVAAIHPNYRLHSQLCGTALREIYAVSGREPCW
CCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
MNPKDAAARGLKNGDIARAYNDRGQILVGIRVTDDIMPGVIRINEGGWYDPADPRRANTL
CCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCHHHCCC
CRYGDVNVLTTSIATSKLAQATSAQTVICEVEKFHGPIPPVRVFDEPDAQASPAGRSSKR
EECCCCEEEEHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVTPKPHPTLDRRAFIKSASALAALGALGVSPFSRGAQAAAPDRTVLSACHWGIFRAR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHH
VRNGRFDRITPWEGDPHPTPMLQGVRDSIYSPTRIKYPMVRRAWLEHGPGADPDGRSTGD
HHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
FVRVSWERAIALVAGELDRVRKHHGNTAIYAGSYGWKSTGKLHSCRVLLWRMLKLYGGFT
EEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHH
SSLSNYSDAATSAVLPYVVGSAGVVDQCTTWPVIAKHTQVLVLWGCNPFNTCQIGWLVPD
HHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCCCCCEEEEEECCC
HNYFDLIKTAKAAGIKVICIDPIRTESCKLLDGEWIAPRPQTDVAMMLGIAHTLYSEKLH
CCHHHHHHHHHHCCEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DEAFLKRYTTGFDAFLAYLTGRTDGTPKTPEWAAEICGIEPAKLRELARTFATHRTMLAL
HHHHHHHHCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEE
GWSTQRQQHGEQVPWMLVTLAAMLGQIGLPGGGFGHAYHYNAGVPTHTSPSLPGMTDGSS
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
VKELRPGCYPGNTSSYCLDEQGPAIPVARVVEMLRNPGKTIDYNGGKLTYPDVKLVYWAG
HHHHCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEECCCCEEECCCEEEEEEEC
GNPFAHHQDRNEMVQAWKKVETFVVHDFQWTASARHADIVLPVTTSYERNDIEQVGDFAL
CCCCCCCCCHHHHHHHHHHHHHHEEECEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHH
SHIVPMKKVIEPLYEARSDYDIFADICAKIDRRDAFTEGLTEMDWIRRFYEKGRLVARAK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEEEECC
GMEMPVFDVFWESDAPLAFPLAKGPTDYVAYADFRADPLLNALGTASGKFEIYSKTIEKM
CCCCCEEEEEECCCCCEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
HYDDCPPHPTWIEPVERLGGPTARFPLHVAAIHPNYRLHSQLCGTALREIYAVSGREPCW
CCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
MNPKDAAARGLKNGDIARAYNDRGQILVGIRVTDDIMPGVIRINEGGWYDPADPRRANTL
CCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCEEEECCCCCCCCCCCHHHCCC
CRYGDVNVLTTSIATSKLAQATSAQTVICEVEKFHGPIPPVRVFDEPDAQASPAGRSSKR
EECCCCEEEEHHHHHHHHHHHCCCCEEEEEHHHHCCCCCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; H+; trimethylamine N-oxide

Specific reaction: NADH + H+ + trimethylamine N-oxide = NAD+ + trimethylamine + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]