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The map label for this gene is lldD [H]

Identifier: 238023660

GI number: 238023660

Start: 204558

End: 205676

Strand: Direct

Name: lldD [H]

Synonym: bglu_2g01780

Alternate gene names: 238023660

Gene position: 204558-205676 (Clockwise)

Preceding gene: 238023659

Following gene: 238023662

Centisome position: 7.24

GC content: 70.87

Gene sequence:

>1119_bases
ATGAGCGGAGAGCCGAACGCACGCGCGGACAGCGCCCCGTACACGATCCCCGACGACACGGTGTCGCTCGCCGATTACGC
GCGGCACTTCGCGCGGCTTTGCGACCCGGCGATTGCCGCTTACATCGATGGCGCGGCAGCCGACGGCATCACGAAGCGCG
ACAATCACGAAGCGTTCACGCGCATGAAGCTGCTGCCGCGCGCGCTGGCCGATCTGGCTGGCGCCAGCGCCAGCAGCGAA
CTGTTCGGCACGCCGCTCGCCTATCCGATCCTGCTCGCGCCCACCGCCTATCATCGTCTCGTGCATCCCGACGGCGAACT
CGCCACGGTCGAGGCAGCGTCGCTGACGCGCACCTGGATGACCGTCAGCGCGCAGGCGAGCGTACCGCTCGAAGCGATCG
CGCAGCGCGCGAGTTCGCCGCTGTGGCTCCAACTCTACTGGCTGCCGCGCCGGGACGATACGCTCACGCTGGTCCGGCGC
GCCGAGCAGGCCGGCTACCGCGCGATCGTTGTCACGCTCGACGCGGTCGTGAGCGGCGCGCGCAACGTCGAGCAGCGCGC
GGGCTTTCGCCTGCCGCATGGCGTGTCGGCCGTCAACCTCGCTGCTTGCGCGCTGCCACCGCCCGCCGTCGCACGCACGG
GTAGCCCGGTGTTCAGCCAGATGCTGGGGGGCGCGCCGACCTGGCCCGACATCGCGTGGCTGGCCGAGCGCAGCGTACTG
CCGATCCTGTTGAAGGGGGTACTGAACCCGGCCGACGTGCAGCAGGCGCTCTCGGCCGGCGCGGCGGGACTGATCGTGTC
GAACCACGGCGGCCGCACACTCGACACGCTGCCGGCCGCGCTCGAGGCGCTGCCGGGCGTTGCGAGCGCAGTTGCCGGGC
GCGTACCCGTGCTGCTCGACGGCGGTATCCGCCGCGGCACCGACGTCGTGAAGGCGCTCGCGCTCGGTGCGTCGGCAGTG
CTGATCGGTCAACCGGTCGTGCACGCGCTTGCCGTCGGGGGCATGCGCGGCGTTGCCCACATGCTGACGATCCTGCAGAC
CGAATTCGAGGCCGCGATGGCGCTCGTCGGCCGAGCGCGGATTCGCGACATCGATGCATCGTTGATCTGGACCCGCTGA

Upstream 100 bases:

>100_bases
TCGCGATCATCGACATTCGCGGCAAGCTCGGTGACCATGATCTCGCGGTGCTGAGCCTCGTGAACCACTACCATAACCTG
CTGCGCCGGTGGTCGGAGCT

Downstream 100 bases:

>100_bases
ACGGCCGAAGAAGCGTTGATCCGCCACCGGTTGCCGGAGATGGTGAACCGGATCAGGATAGCCAGTTCAAGCCGGATGCG
CTCACCGAGCCGGTGCCGGG

Product: FMN-dependent alpha-hydroxy acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSGEPNARADSAPYTIPDDTVSLADYARHFARLCDPAIAAYIDGAAADGITKRDNHEAFTRMKLLPRALADLAGASASSE
LFGTPLAYPILLAPTAYHRLVHPDGELATVEAASLTRTWMTVSAQASVPLEAIAQRASSPLWLQLYWLPRRDDTLTLVRR
AEQAGYRAIVVTLDAVVSGARNVEQRAGFRLPHGVSAVNLAACALPPPAVARTGSPVFSQMLGGAPTWPDIAWLAERSVL
PILLKGVLNPADVQQALSAGAAGLIVSNHGGRTLDTLPAALEALPGVASAVAGRVPVLLDGGIRRGTDVVKALALGASAV
LIGQPVVHALAVGGMRGVAHMLTILQTEFEAAMALVGRARIRDIDASLIWTR

Sequences:

>Translated_372_residues
MSGEPNARADSAPYTIPDDTVSLADYARHFARLCDPAIAAYIDGAAADGITKRDNHEAFTRMKLLPRALADLAGASASSE
LFGTPLAYPILLAPTAYHRLVHPDGELATVEAASLTRTWMTVSAQASVPLEAIAQRASSPLWLQLYWLPRRDDTLTLVRR
AEQAGYRAIVVTLDAVVSGARNVEQRAGFRLPHGVSAVNLAACALPPPAVARTGSPVFSQMLGGAPTWPDIAWLAERSVL
PILLKGVLNPADVQQALSAGAAGLIVSNHGGRTLDTLPAALEALPGVASAVAGRVPVLLDGGIRRGTDVVKALALGASAV
LIGQPVVHALAVGGMRGVAHMLTILQTEFEAAMALVGRARIRDIDASLIWTR
>Mature_371_residues
SGEPNARADSAPYTIPDDTVSLADYARHFARLCDPAIAAYIDGAAADGITKRDNHEAFTRMKLLPRALADLAGASASSEL
FGTPLAYPILLAPTAYHRLVHPDGELATVEAASLTRTWMTVSAQASVPLEAIAQRASSPLWLQLYWLPRRDDTLTLVRRA
EQAGYRAIVVTLDAVVSGARNVEQRAGFRLPHGVSAVNLAACALPPPAVARTGSPVFSQMLGGAPTWPDIAWLAERSVLP
ILLKGVLNPADVQQALSAGAAGLIVSNHGGRTLDTLPAALEALPGVASAVAGRVPVLLDGGIRRGTDVVKALALGASAVL
IGQPVVHALAVGGMRGVAHMLTILQTEFEAAMALVGRARIRDIDASLIWTR

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=355, Percent_Identity=39.7183098591549, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI54234014, Length=353, Percent_Identity=37.9603399433428, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI7705393, Length=353, Percent_Identity=37.9603399433428, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1790033, Length=365, Percent_Identity=33.6986301369863, Blast_Score=185, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI193208036, Length=352, Percent_Identity=34.375, Blast_Score=205, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32566217, Length=269, Percent_Identity=30.4832713754647, Blast_Score=129, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323587, Length=385, Percent_Identity=30.6493506493506, Blast_Score=175, Evalue=8e-45,
Organism=Drosophila melanogaster, GI78707188, Length=354, Percent_Identity=38.7005649717514, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281363140, Length=354, Percent_Identity=38.7005649717514, Blast_Score=232, Evalue=2e-61,
Organism=Drosophila melanogaster, GI78707190, Length=354, Percent_Identity=38.7005649717514, Blast_Score=232, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 38971; Mature: 38840

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEPNARADSAPYTIPDDTVSLADYARHFARLCDPAIAAYIDGAAADGITKRDNHEAFT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHCCCCCCCCHHHHH
RMKLLPRALADLAGASASSELFGTPLAYPILLAPTAYHRLVHPDGELATVEAASLTRTWM
HHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHCCCHHHHHHCCCCCCEEEEEHHHHHHHHE
TVSAQASVPLEAIAQRASSPLWLQLYWLPRRDDTLTLVRRAEQAGYRAIVVTLDAVVSGA
EEECCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEHHHHHHCH
RNVEQRAGFRLPHGVSAVNLAACALPPPAVARTGSPVFSQMLGGAPTWPDIAWLAERSVL
HHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHCCCCHHHHHHHCCCCCCCHHHHHHHCCHH
PILLKGVLNPADVQQALSAGAAGLIVSNHGGRTLDTLPAALEALPGVASAVAGRVPVLLD
HHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEC
GGIRRGTDVVKALALGASAVLIGQPVVHALAVGGMRGVAHMLTILQTEFEAAMALVGRAR
CCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRDIDASLIWTR
HHCCCCEEEECC
>Mature Secondary Structure 
SGEPNARADSAPYTIPDDTVSLADYARHFARLCDPAIAAYIDGAAADGITKRDNHEAFT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCHHHCCCCCCCCHHHHH
RMKLLPRALADLAGASASSELFGTPLAYPILLAPTAYHRLVHPDGELATVEAASLTRTWM
HHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHCCCHHHHHHCCCCCCEEEEEHHHHHHHHE
TVSAQASVPLEAIAQRASSPLWLQLYWLPRRDDTLTLVRRAEQAGYRAIVVTLDAVVSGA
EEECCCCCCHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCCEEEEEEHHHHHHCH
RNVEQRAGFRLPHGVSAVNLAACALPPPAVARTGSPVFSQMLGGAPTWPDIAWLAERSVL
HHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHCCCCHHHHHHHCCCCCCCHHHHHHHCCHH
PILLKGVLNPADVQQALSAGAAGLIVSNHGGRTLDTLPAALEALPGVASAVAGRVPVLLD
HHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHCCCCEEEC
GGIRRGTDVVKALALGASAVLIGQPVVHALAVGGMRGVAHMLTILQTEFEAAMALVGRAR
CCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRDIDASLIWTR
HHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA