The gene/protein map for NC_012721 is currently unavailable.
Definition Burkholderia glumae BGR1 chromosome chromosome 2, complete sequence.
Accession NC_012721
Length 2,827,333

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The map label for this gene is fabG2 [H]

Identifier: 238023586

GI number: 238023586

Start: 92738

End: 93481

Strand: Reverse

Name: fabG2 [H]

Synonym: bglu_2g00890

Alternate gene names: 238023586

Gene position: 93481-92738 (Counterclockwise)

Preceding gene: 238023587

Following gene: 238023584

Centisome position: 3.31

GC content: 71.37

Gene sequence:

>744_bases
ATGGAACCTAGAACCGTCGTCGTGACCGGCGCCGCGCGCGGCCTCGGCGCCGCGCTCGCCGCGCGCTTTCACGCAGCCGG
CTATCGGGTCGCGCTGGCCGACGTCGCGCTCGACGCCGCCCAGGCCACGGCGCGGGCACTGAGCCCGGACGGCTCGCAGG
CCGTCGCGCTGTCGCTCGACGTGACCCGCAAGGACGATTTCAGCGCCGCGCTCGACGCCGTCACGGCACGCTGGGGGCGC
GTCGACGTGCTCGTCAACAACGCCGGCGCCTCGAAGGTGGTGCCGCTGATGGACATCACGGCCGAGCAGTTCGACCAGGT
GATCGACGTGAACCTGCGCAGCGTGCTGTTCGGCTGCCAGGTGTTCGGCCAGTATTTCGCCGATCAGGGTGGCGGGCGCA
TCGTCAACATCGCCTCGCTGGCGGGCCAGAACGGCGGCTCGGCCACCGGCGCGCACTACGCCGCCGCGAAGGGCGGCACG
CTCACGCTGACCAAGGTGTTCGCCCGCGATCTGGCCGCACGCGGGGTCACGGTCAACGCGATCTCGCCGGGGCCGCTCGA
CCTGCCGATCGTCCACCAAAGCGTGCCGGCGGACCGGCTCGAAAAGGTGATCTCGACGATCCCGGTCGGCCGGCTCGGCC
CCGCCGACTACATCGCCGACGTGGCGGTGCTGCTCGCCTCGGGCAATGCCTACTTCGCCAACGGGGCCTGCTGGGACGTC
AACGGCGGCCTGTACATGCGATGA

Upstream 100 bases:

>100_bases
TCGGCCGCGAACTGGTGGTGCCGCCCGCCGCGGCCGCGGCCTGAGCGCACCGCCCGCAACCGGGCGCGCGCCGCGCGCCG
TCAGACAAGGAGCATCCCGG

Downstream 100 bases:

>100_bases
AGCCGGGGCCCGCCCACCGCTCGGCATCGCTTGCGGCCGCCGGGCCGCAACGCGCGCGGGTTCTGCGCCCGGCGGGCGGC
GCGCACCGGGCGCGATACAC

Product: Short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEPRTVVVTGAARGLGAALAARFHAAGYRVALADVALDAAQATARALSPDGSQAVALSLDVTRKDDFSAALDAVTARWGR
VDVLVNNAGASKVVPLMDITAEQFDQVIDVNLRSVLFGCQVFGQYFADQGGGRIVNIASLAGQNGGSATGAHYAAAKGGT
LTLTKVFARDLAARGVTVNAISPGPLDLPIVHQSVPADRLEKVISTIPVGRLGPADYIADVAVLLASGNAYFANGACWDV
NGGLYMR

Sequences:

>Translated_247_residues
MEPRTVVVTGAARGLGAALAARFHAAGYRVALADVALDAAQATARALSPDGSQAVALSLDVTRKDDFSAALDAVTARWGR
VDVLVNNAGASKVVPLMDITAEQFDQVIDVNLRSVLFGCQVFGQYFADQGGGRIVNIASLAGQNGGSATGAHYAAAKGGT
LTLTKVFARDLAARGVTVNAISPGPLDLPIVHQSVPADRLEKVISTIPVGRLGPADYIADVAVLLASGNAYFANGACWDV
NGGLYMR
>Mature_247_residues
MEPRTVVVTGAARGLGAALAARFHAAGYRVALADVALDAAQATARALSPDGSQAVALSLDVTRKDDFSAALDAVTARWGR
VDVLVNNAGASKVVPLMDITAEQFDQVIDVNLRSVLFGCQVFGQYFADQGGGRIVNIASLAGQNGGSATGAHYAAAKGGT
LTLTKVFARDLAARGVTVNAISPGPLDLPIVHQSVPADRLEKVISTIPVGRLGPADYIADVAVLLASGNAYFANGACWDV
NGGLYMR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=33.7349397590361, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=29.9180327868852, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=36.078431372549, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=29.9595141700405, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=24.609375, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=34.5098039215686, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=27.6422764227642, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=32.15859030837, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI31542939, Length=209, Percent_Identity=29.6650717703349, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI66933014, Length=190, Percent_Identity=27.3684210526316, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=24.7967479674797, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI4503301, Length=221, Percent_Identity=26.2443438914027, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=26.7676767676768, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI224922801, Length=167, Percent_Identity=30.5389221556886, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=35.6275303643725, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=31.6, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=29.3388429752066, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=30.0411522633745, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=29.718875502008, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=29.5546558704453, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=30.9917355371901, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=30.3501945525292, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=28.4518828451883, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=24.4, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786812, Length=236, Percent_Identity=29.6610169491525, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=32.3886639676113, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=34.9593495934959, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=28.7449392712551, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=28.2868525896414, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=32.295719844358, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=26.8292682926829, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=233, Percent_Identity=29.1845493562232, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=28.3400809716599, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=26.2948207171315, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193203117, Length=182, Percent_Identity=30.2197802197802, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193203115, Length=182, Percent_Identity=30.2197802197802, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=240, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=246, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=236, Percent_Identity=26.271186440678, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=240, Percent_Identity=26.25, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=244, Percent_Identity=26.6393442622951, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=26.1538461538462, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=24.7967479674797, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=238, Percent_Identity=26.4705882352941, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=24.901185770751, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=238, Percent_Identity=26.0504201680672, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=190, Percent_Identity=27.8947368421053, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=25.3061224489796, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=248, Percent_Identity=26.2096774193548, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=240, Percent_Identity=26.25, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=23.7113402061856, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=240, Percent_Identity=28.75, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=154, Percent_Identity=29.2207792207792, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=25.4098360655738, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=25.6, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=188, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=191, Percent_Identity=25.6544502617801, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=32.2751322751323, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=188, Percent_Identity=27.1276595744681, Blast_Score=62, Evalue=6e-11,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=32.6693227091633, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=31.6872427983539, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=29.0322580645161, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571526, Length=248, Percent_Identity=29.4354838709677, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.1023622047244, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=29.718875502008, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=27.4900398406374, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=28.7937743190661, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364892, Length=153, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI116007236, Length=223, Percent_Identity=30.0448430493274, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644337, Length=246, Percent_Identity=28.8617886178862, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=28.4552845528455, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=27.2277227722772, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 25392; Mature: 25392

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MEPRTVVVTGAARGLGAALAARFHAAGYRVALADVALDAAQATARALSPDGSQAVALSLD
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEE
VTRKDDFSAALDAVTARWGRVDVLVNNAGASKVVPLMDITAEQFDQVIDVNLRSVLFGCQ
ECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEHHHHCCHHHHHHHHCCHHHHHHHHHH
VFGQYFADQGGGRIVNIASLAGQNGGSATGAHYAAAKGGTLTLTKVFARDLAARGVTVNA
HHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCEEEEE
ISPGPLDLPIVHQSVPADRLEKVISTIPVGRLGPADYIADVAVLLASGNAYFANGACWDV
CCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEC
NGGLYMR
CCCEEEC
>Mature Secondary Structure
MEPRTVVVTGAARGLGAALAARFHAAGYRVALADVALDAAQATARALSPDGSQAVALSLD
CCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEE
VTRKDDFSAALDAVTARWGRVDVLVNNAGASKVVPLMDITAEQFDQVIDVNLRSVLFGCQ
ECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEHHHHCCHHHHHHHHCCHHHHHHHHHH
VFGQYFADQGGGRIVNIASLAGQNGGSATGAHYAAAKGGTLTLTKVFARDLAARGVTVNA
HHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCEEEEE
ISPGPLDLPIVHQSVPADRLEKVISTIPVGRLGPADYIADVAVLLASGNAYFANGACWDV
CCCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEECCEEEEC
NGGLYMR
CCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]