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The map label for this gene is mhpA [H]

Identifier: 238023573

GI number: 238023573

Start: 76303

End: 77931

Strand: Direct

Name: mhpA [H]

Synonym: bglu_2g00750

Alternate gene names: 238023573

Gene position: 76303-77931 (Clockwise)

Preceding gene: 238023572

Following gene: 238023574

Centisome position: 2.7

GC content: 67.71

Gene sequence:

>1629_bases
ATGAAAGCGAACCACCGGCACCGCACCTCGGTCGCCATCGTCGGTGCGGGGCCGAACGGCGCGGCCATGGCGAACCTGCT
CGGCCTGTACGGCGTCGATACGATCGTTGTCGAGCGGGCGCCGCAGATCGTCGAATTCCCGCGCGCGGTGGGCATCGACG
ACGAGGCGCTGCGGCTGTTCCAGACGGCCGGTCTGGCCGACGAGCTGAGCCGCGACATCATCCAGAACGTGCCGCTGCGC
ATGTTCAAGGCGAACGGCGAATGTTTCGCCGACATCCGTCCGTCGCTACGCGAGTTCGGCTGGTGGCGCCGCAACATCTT
CATGCAGCACCTGGCCGAGCGCACGCTGCGCGACGCACTGAAGCGCTACCCGCACGTGTCGCTGCGCACGGGCGAGGAGC
TTGTCGGTCTGACGCAGGACGAGACGGGCGTGAGGCTTCAGATATGCGCCGCCGACGGGCAGCGATACGAACTCGACGCC
GACTACGTGGTGGCAGCCGACGGCGGACGCAGCCCGGTCCGTGAGATGCTGGGCATCAAGCTGGCCGGCACGACCCATCC
GCTCAAATGGGTCGTGGTCGACGTGAAGAACGCGCAGCTCGACCAGCCGTGTACCGCGCTGAACTGCGATCCGCGGCGCC
CGAACGTCTGCATTTATCTGCCGTTCAATTATCGACGCTGGGAATTTCTCGTGTTTCCGCACGAGGACGAGCAGGCGATC
GCGCAACCGGAGTCGGTCCGCGCGCTGATCGCGCCGTACGTCGACGACGTCGATCGCCTCGAGATCGTGCGTGCGCGCAC
CTACACGCATCACTCGCGCGTGGCCGAACGTTTCGTCGCCGGCCGGGTGGCGCTCATCGGCGATGCCGCGCACCTGAGCC
CGCCGTGGATCGGCCAGGGGCTGAATGCGGGGCTGCGCGACGTGGGCAATCTGGCGTGGAAGCTGGCGGGAGTCGTGAGC
GGCAGCTTGCAACCGGGTGTGATCTCCAGCTACGAATCGGAGCGCCGCGATCACGCCAAGGCGATGATCGATCTCGCCGA
CACGTTCGGCGCGATGCTGATGCCCACCAGCCGTCTGGTCGCGTTCCTGCGCGACCGCTTGCTCGGACTCGCGCGCTATG
CGCCGGGCCTGAAGGACTATGTGCTGCAGATGCGCTTCAAGCCGATGCCGAGCTATACGCGCGGGATGGTGGTGACGGGC
GCGTCGGACGCCGTCGGGCGCATGATCGTCCAACCCGAGGTCGAAGCGGCGGACGGCGCACGTCGCAAGCTCGACGAGGT
GCTCGGCCCGTGGTTTTCGATCATCGGCTGGCGATGCGATCCGCAAGCGTGCCTGAGCGACCAGGATCGCGCGTTCTGGG
CCGCGCTGGGCGCGAGGTTCGTGCAGATCGTGCGTTCGCGCAGCGGAACCTGCCGCGAGCAGCGCATCACGAGCGCGCAC
GGCAGCGAGTGCGTCGAGGACGTCGACAACGCGATGGCCGACTGGTTCACCAGGCATCCCGGGCCGCTCGTGGTCGTCCG
TCCGGACCGCTATGTGGCGGCGCAAACGGACGCGGCCGGCATGGCCGGCGTGACCGCGGCGTTCCAGGCATTTGCATCGC
CGCAACGGGAGGCCGCGCATGTTTGTTGA

Upstream 100 bases:

>100_bases
ATTACGTGCACGACGATCAGCCGGCGGCATTCAATCGCGCGCTGCGCGGCTGGCTCGATCGTCTCGATGACGCGGCATGG
CGCGCGGGGGGGCGGGTCCA

Downstream 100 bases:

>100_bases
GCAACGCACCTACACGCTGGTGCCGGGCGGCGTCGCCGAGTATCTGCAACTGTACGCGGCCTGCGGCCGTGCCGCCCAGG
AGCGGGCGCTCGGCACGATG

Product: 3-(3-hydroxyphenyl)propionate hydroxylase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKANHRHRTSVAIVGAGPNGAAMANLLGLYGVDTIVVERAPQIVEFPRAVGIDDEALRLFQTAGLADELSRDIIQNVPLR
MFKANGECFADIRPSLREFGWWRRNIFMQHLAERTLRDALKRYPHVSLRTGEELVGLTQDETGVRLQICAADGQRYELDA
DYVVAADGGRSPVREMLGIKLAGTTHPLKWVVVDVKNAQLDQPCTALNCDPRRPNVCIYLPFNYRRWEFLVFPHEDEQAI
AQPESVRALIAPYVDDVDRLEIVRARTYTHHSRVAERFVAGRVALIGDAAHLSPPWIGQGLNAGLRDVGNLAWKLAGVVS
GSLQPGVISSYESERRDHAKAMIDLADTFGAMLMPTSRLVAFLRDRLLGLARYAPGLKDYVLQMRFKPMPSYTRGMVVTG
ASDAVGRMIVQPEVEAADGARRKLDEVLGPWFSIIGWRCDPQACLSDQDRAFWAALGARFVQIVRSRSGTCREQRITSAH
GSECVEDVDNAMADWFTRHPGPLVVVRPDRYVAAQTDAAGMAGVTAAFQAFASPQREAAHVC

Sequences:

>Translated_542_residues
MKANHRHRTSVAIVGAGPNGAAMANLLGLYGVDTIVVERAPQIVEFPRAVGIDDEALRLFQTAGLADELSRDIIQNVPLR
MFKANGECFADIRPSLREFGWWRRNIFMQHLAERTLRDALKRYPHVSLRTGEELVGLTQDETGVRLQICAADGQRYELDA
DYVVAADGGRSPVREMLGIKLAGTTHPLKWVVVDVKNAQLDQPCTALNCDPRRPNVCIYLPFNYRRWEFLVFPHEDEQAI
AQPESVRALIAPYVDDVDRLEIVRARTYTHHSRVAERFVAGRVALIGDAAHLSPPWIGQGLNAGLRDVGNLAWKLAGVVS
GSLQPGVISSYESERRDHAKAMIDLADTFGAMLMPTSRLVAFLRDRLLGLARYAPGLKDYVLQMRFKPMPSYTRGMVVTG
ASDAVGRMIVQPEVEAADGARRKLDEVLGPWFSIIGWRCDPQACLSDQDRAFWAALGARFVQIVRSRSGTCREQRITSAH
GSECVEDVDNAMADWFTRHPGPLVVVRPDRYVAAQTDAAGMAGVTAAFQAFASPQREAAHVC
>Mature_542_residues
MKANHRHRTSVAIVGAGPNGAAMANLLGLYGVDTIVVERAPQIVEFPRAVGIDDEALRLFQTAGLADELSRDIIQNVPLR
MFKANGECFADIRPSLREFGWWRRNIFMQHLAERTLRDALKRYPHVSLRTGEELVGLTQDETGVRLQICAADGQRYELDA
DYVVAADGGRSPVREMLGIKLAGTTHPLKWVVVDVKNAQLDQPCTALNCDPRRPNVCIYLPFNYRRWEFLVFPHEDEQAI
AQPESVRALIAPYVDDVDRLEIVRARTYTHHSRVAERFVAGRVALIGDAAHLSPPWIGQGLNAGLRDVGNLAWKLAGVVS
GSLQPGVISSYESERRDHAKAMIDLADTFGAMLMPTSRLVAFLRDRLLGLARYAPGLKDYVLQMRFKPMPSYTRGMVVTG
ASDAVGRMIVQPEVEAADGARRKLDEVLGPWFSIIGWRCDPQACLSDQDRAFWAALGARFVQIVRSRSGTCREQRITSAH
GSECVEDVDNAMADWFTRHPGPLVVVRPDRYVAAQTDAAGMAGVTAAFQAFASPQREAAHVC

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=515, Percent_Identity=42.9126213592233, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 60006; Mature: 60006

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKANHRHRTSVAIVGAGPNGAAMANLLGLYGVDTIVVERAPQIVEFPRAVGIDDEALRLF
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
QTAGLADELSRDIIQNVPLRMFKANGECFADIRPSLREFGWWRRNIFMQHLAERTLRDAL
HHCCCHHHHHHHHHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYPHVSLRTGEELVGLTQDETGVRLQICAADGQRYELDADYVVAADGGRSPVREMLGIK
HHCCCEEEECCHHHCCCCCCCCCCEEEEEECCCCEEEECCCEEEEECCCCHHHHHHHCEE
LAGTTHPLKWVVVDVKNAQLDQPCTALNCDPRRPNVCIYLPFNYRRWEFLVFPHEDEQAI
EECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHH
AQPESVRALIAPYVDDVDRLEIVRARTYTHHSRVAERFVAGRVALIGDAAHLSPPWIGQG
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCCCC
LNAGLRDVGNLAWKLAGVVSGSLQPGVISSYESERRDHAKAMIDLADTFGAMLMPTSRLV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLRDRLLGLARYAPGLKDYVLQMRFKPMPSYTRGMVVTGASDAVGRMIVQPEVEAADGA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCEEECCCCCCCCHH
RRKLDEVLGPWFSIIGWRCDPQACLSDQDRAFWAALGARFVQIVRSRSGTCREQRITSAH
HHHHHHHHCHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
GSECVEDVDNAMADWFTRHPGPLVVVRPDRYVAAQTDAAGMAGVTAAFQAFASPQREAAH
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHCC
VC
CC
>Mature Secondary Structure
MKANHRHRTSVAIVGAGPNGAAMANLLGLYGVDTIVVERAPQIVEFPRAVGIDDEALRLF
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHCCCCHHHHHHH
QTAGLADELSRDIIQNVPLRMFKANGECFADIRPSLREFGWWRRNIFMQHLAERTLRDAL
HHCCCHHHHHHHHHHCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRYPHVSLRTGEELVGLTQDETGVRLQICAADGQRYELDADYVVAADGGRSPVREMLGIK
HHCCCEEEECCHHHCCCCCCCCCCEEEEEECCCCEEEECCCEEEEECCCCHHHHHHHCEE
LAGTTHPLKWVVVDVKNAQLDQPCTALNCDPRRPNVCIYLPFNYRRWEFLVFPHEDEQAI
EECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCHHH
AQPESVRALIAPYVDDVDRLEIVRARTYTHHSRVAERFVAGRVALIGDAAHLSPPWIGQG
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCCCC
LNAGLRDVGNLAWKLAGVVSGSLQPGVISSYESERRDHAKAMIDLADTFGAMLMPTSRLV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AFLRDRLLGLARYAPGLKDYVLQMRFKPMPSYTRGMVVTGASDAVGRMIVQPEVEAADGA
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCHHHCCEEECCCCCCCCHH
RRKLDEVLGPWFSIIGWRCDPQACLSDQDRAFWAALGARFVQIVRSRSGTCREQRITSAH
HHHHHHHHCHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCC
GSECVEDVDNAMADWFTRHPGPLVVVRPDRYVAAQTDAAGMAGVTAAFQAFASPQREAAH
HHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCHHHCC
VC
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA