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The map label for this gene is dhaR [H]

Identifier: 238023547

GI number: 238023547

Start: 51960

End: 52526

Strand: Direct

Name: dhaR [H]

Synonym: bglu_2g00480

Alternate gene names: 238023547

Gene position: 51960-52526 (Clockwise)

Preceding gene: 238023546

Following gene: 238023548

Centisome position: 1.84

GC content: 65.96

Gene sequence:

>567_bases
ATGGAAACGAAACCGAATGTCCGCCAACAACTGCTCGAACATGCGATCGAGCTGATGATGCTGCGGGGCTACAACGGCTT
CAGTTACCGCGACCTGTCGGCACTGGTCGGCGTCAAGACCTCGAGCATCCACTACTACTTTCCGTCCAAGGACGATCTGG
TGCTGGAAGCGGTCGAGACCTACAGCGCGAACTTGCTGGCCGGCATCGACGGGATCGACCCCTCTCTGCCGGCGGACGCG
AAGCTGGGCCGCTACACGCAACTGTTCGGCAAGGTGCTCGGCGACGGCCGCCGGATCTGCCTGTGCGGGATGCTGGCGGC
GGACATCGAAGCCTTGCCGGATTCGGTCCGGCAGGCGGTGCAGGCGTTCTTCGGCATCAACGAACGCTGGCTCGCCGCCT
TGCTCGCGCAGGGCGCCGAGGACGGCACGCTGGCTTTCAGCGGTGCGCCCGAGGATGCGGCCCGCACGCTCTACGCGGCC
TACCAGGGCGCGGTGCTGGCGAGCCGGCTGTTCCAATCGAAGGCGCGCCTCGACGAAGTCGAGCGGGCCTGGAAGAAAGC
GCCGTGA

Upstream 100 bases:

>100_bases
GGCGCGCCGTTGAGGCGGCGAACGATGGCCGCGCCGGCCCGCCCAGGAATTTCTCAAAAACATCTTGACTCTCTATCTTC
CAGTAGATAAAGTTCGATCC

Downstream 100 bases:

>100_bases
CGGCGCCGGTCGAAATACACGAAAAGGCGGCCCGCCGCCTTTTTATTGGGATTATTTATCTATCTATTGGTAGATAAATA
ATCGAGAGCAGACGCTCGTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
METKPNVRQQLLEHAIELMMLRGYNGFSYRDLSALVGVKTSSIHYYFPSKDDLVLEAVETYSANLLAGIDGIDPSLPADA
KLGRYTQLFGKVLGDGRRICLCGMLAADIEALPDSVRQAVQAFFGINERWLAALLAQGAEDGTLAFSGAPEDAARTLYAA
YQGAVLASRLFQSKARLDEVERAWKKAP

Sequences:

>Translated_188_residues
METKPNVRQQLLEHAIELMMLRGYNGFSYRDLSALVGVKTSSIHYYFPSKDDLVLEAVETYSANLLAGIDGIDPSLPADA
KLGRYTQLFGKVLGDGRRICLCGMLAADIEALPDSVRQAVQAFFGINERWLAALLAQGAEDGTLAFSGAPEDAARTLYAA
YQGAVLASRLFQSKARLDEVERAWKKAP
>Mature_188_residues
METKPNVRQQLLEHAIELMMLRGYNGFSYRDLSALVGVKTSSIHYYFPSKDDLVLEAVETYSANLLAGIDGIDPSLPADA
KLGRYTQLFGKVLGDGRRICLCGMLAADIEALPDSVRQAVQAFFGINERWLAALLAQGAEDGTLAFSGAPEDAARTLYAA
YQGAVLASRLFQSKARLDEVERAWKKAP

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 20546; Mature: 20546

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKPNVRQQLLEHAIELMMLRGYNGFSYRDLSALVGVKTSSIHYYFPSKDDLVLEAVET
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEECCEEEECCCCCCHHHHHHHH
YSANLLAGIDGIDPSLPADAKLGRYTQLFGKVLGDGRRICLCGMLAADIEALPDSVRQAV
HCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHH
QAFFGINERWLAALLAQGAEDGTLAFSGAPEDAARTLYAAYQGAVLASRLFQSKARLDEV
HHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAWKKAP
HHHHHCCC
>Mature Secondary Structure
METKPNVRQQLLEHAIELMMLRGYNGFSYRDLSALVGVKTSSIHYYFPSKDDLVLEAVET
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEECCEEEECCCCCCHHHHHHHH
YSANLLAGIDGIDPSLPADAKLGRYTQLFGKVLGDGRRICLCGMLAADIEALPDSVRQAV
HCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHH
QAFFGINERWLAALLAQGAEDGTLAFSGAPEDAARTLYAAYQGAVLASRLFQSKARLDEV
HHHHCCCHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAWKKAP
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]