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The map label for this gene is marR [H]

Identifier: 237814414

GI number: 237814414

Start: 4034645

End: 4035142

Strand: Direct

Name: marR [H]

Synonym: GBP346_A4212

Alternate gene names: 237814414

Gene position: 4034645-4035142 (Clockwise)

Preceding gene: 237814411

Following gene: 237814415

Centisome position: 98.44

GC content: 69.48

Gene sequence:

>498_bases
TTGACGATGAGCGGCCTTTACGACCCGGAGCACATCGAGCTCGAATCGAGCCTCGGCTATTACCTGACGAAGGCGCGGCA
GGCGCTCGTCGAGCGGCTCGACCGCGCGCTCGGCCCGCTCGAGCTGACCGCGCAGCAGATCAGCGTGATCCTGTTGCTCG
CGCGCGGCTATGCGCGTACGCCGTTCGAGCTGTCGCGCAAGCTGTCATACGACAGCGGTTCGATGACGCGCATGCTCGAC
CGGCTCGAGAAGAAGGGCTTCGTCGTGCGCGCGCGCAGCGAATCGGACCGCCGCGTGATCGAGCTCGCGCTGACCGAGCG
CGGCGCGCACGCGGCGCGGGCGCTGCCTGCGCTGATCGCGACCGAGCTGAACACGCAGCTCGAGGGTTTTTCGGCCGATG
AGCTCGCGCTGTTGACGGACCTGCTGCGGCGCTTCATCGCGAATGCGCCGGGCGCGGCCGACGCCGCGTGCGCCGAACCG
CCGCCGGATCAGCGCTGA

Upstream 100 bases:

>100_bases
CATTGACTGAAATAATATTGACTATGCAATAAATATTCAAGATACTGGCGGCGTTTTTCTTGGAATGCACTGTTGCGGCT
CGTGCAATCGACCGGACAGC

Downstream 100 bases:

>100_bases
CCGGGAAAAACGATGAACGGCCTTCGGATCGCGACCCGTTTGCCGCCTATTTATCTGTCTGGGCAGAAGCTGACAGGACA
CTTACTGTCGACCGATGCCG

Product: transcriptional regulator, MarR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKLSYDSGSMTRMLD
RLEKKGFVVRARSESDRRVIELALTERGAHAARALPALIATELNTQLEGFSADELALLTDLLRRFIANAPGAADAACAEP
PPDQR

Sequences:

>Translated_165_residues
MTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKLSYDSGSMTRMLD
RLEKKGFVVRARSESDRRVIELALTERGAHAARALPALIATELNTQLEGFSADELALLTDLLRRFIANAPGAADAACAEP
PPDQR
>Mature_164_residues
TMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYARTPFELSRKLSYDSGSMTRMLDR
LEKKGFVVRARSESDRRVIELALTERGAHAARALPALIATELNTQLEGFSADELALLTDLLRRFIANAPGAADAACAEPP
PDQR

Specific function: Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081927, Length=130, Percent_Identity=35.3846153846154, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 18228; Mature: 18097

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYART
CCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
PFELSRKLSYDSGSMTRMLDRLEKKGFVVRARSESDRRVIELALTERGAHAARALPALIA
CHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TELNTQLEGFSADELALLTDLLRRFIANAPGAADAACAEPPPDQR
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TMSGLYDPEHIELESSLGYYLTKARQALVERLDRALGPLELTAQQISVILLLARGYART
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
PFELSRKLSYDSGSMTRMLDRLEKKGFVVRARSESDRRVIELALTERGAHAARALPALIA
CHHHHHHCCCCCCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHH
TELNTQLEGFSADELALLTDLLRRFIANAPGAADAACAEPPPDQR
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 8282690; 7768850; 10760140 [H]