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The map label for this gene is qseC [H]

Identifier: 237814385

GI number: 237814385

Start: 4005864

End: 4007330

Strand: Direct

Name: qseC [H]

Synonym: GBP346_A4183

Alternate gene names: 237814385

Gene position: 4005864-4007330 (Clockwise)

Preceding gene: 237814384

Following gene: 237814390

Centisome position: 97.74

GC content: 69.26

Gene sequence:

>1467_bases
GTGACCAGCCTGCGCCGCACGCTGCTGCGGCGTTTAGCCGCGCCGCTGTCGATGCTCGCGCTGATGAGCGGCCTCATTGC
CTACTGGCTTGCGTGGCAATACACGCAGCACGTCGTCGATCGCTCGCTCGCCGATCTCGCATCGGCGATCTCCAAGCAGA
TCCAGATCGCCGGCCCCGACGCGCCGTTCACGGTGCCGCCGCTCGCACAGGCGATGTTCTCCGATCCGACCGAGCAATTG
ATCTACCGGATCAGCGACGGCGAACACGAGCTCGCCGGCGATCCGAAGCTGCCGCTGCAAGGCACGAGCGTGCGCCGGAT
GCATGTCGCCTATGTATTCGAGGCCGAGTACGACAACCAGGCGGTGCGCGTCGCGCAAGTGCGCGTCGAGCAGACGGAAA
GCGGCAATCCGATGATCGTCGAGGTCGCGCAGCCGGTGCGCTATCGTTACCGGATCGCGGCGGAATTCCTGATCGCGATC
ATGATGCCGCTGCTGCTGCTGCTGCTCGCCGGCTGGGGAATCGTGTGGCGCGTCGTCAACCAGCAGCTCGGCCCGCTCAC
GCATCTCGCCGATTCGCTGAACCGGCAGACGCACACGTCGCTCGAGCCCGTCGATGAAACCGAGGTGCCGCTCGAGATCC
GGCCGCTCACGAGCGCGATGAATGCGCTGCTCGGCCGCCTGAAAACCGCACTCGACGCGCAGCGCAAGTTCATCGCCGAT
GCCGCGCATCAGCTGCGCACGCCGCTCACCGCGATCAAGCTGCACGCGGAGCAGGCGGCCGTTGCGCGCGATCCGCAACA
GGCGCTGACCGCGGTGCGCGAGCTGCGCTCGGCGGCCGATCGCGCCGTGCGGCTGTCAAACCAGTTGCTGTCGCTCGCGC
GCGCGGAGCCGGGCGAGCAGGCGGCCCGCTTCGTCGATGTCGATCTGGCCGCCCTCGCATTCGAAACCGGTGCCGAATGG
GTGCCGCGCGCGCTCGCCGCGCATGTCGACCTCGGCTTCCAACGCGGCGACGGCCGCGGCGACGATGAGCCGCTCGTCGT
GCGCGGCAACCCGGTGCTGCTGCGCGAAGTGATCGCGAACCTGCTCGACAACGCGCTGAAATACGTGCCGCTCGCGCGGC
CGCAGGGCGCGCGGATCACGATGGACGTGTCGCGGATCGCGCTCGACGAAGGCCACGCGGCGGCCGAGATCGTCGTCGAG
GACAACGGCTCGGGCGTGCCCGCCACGCAGCAGGCGGACCTGTTCAAGCGCTTCTTCCGCGGCGACGCGCAAAGCGGCAA
CGGCGTCGAGACGGGCGCGGGCCTCGGCCTCGCGATCGTCCACGACATCATCGCGATGCACGGCGGAACCGTATCGTACG
CGGATGCGCCGGAAGGCGGCTCGTGCTTCATCGTACGCGTGCCGCTCGCGGACACGCCGTCCACGCCCGCGCCGCCCCCC
TGTGAATCGCCGGCCGCTTCGGCCTGA

Upstream 100 bases:

>100_bases
GTGCGGCGCGCCGCAGCCGCGCGCGCGGCACGCTTGCCCTGCGCCGCTTCGCGAAGCGGCGCTTATTCTTTTCTTTCGCG
CGATGTCCCCTGATCCGGCT

Downstream 100 bases:

>100_bases
CGCCGTGGCCGGGCGCGATCGCGCTCGGCCACGCCAAGCCACAGGGCTCGACGCGCGCGGCCGAGCCGCGAGTGCACCGC
GCCATTGCCGCGCGATCGCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTSLRRTLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVVDRSLADLASAISKQIQIAGPDAPFTVPPLAQAMFSDPTEQL
IYRISDGEHELAGDPKLPLQGTSVRRMHVAYVFEAEYDNQAVRVAQVRVEQTESGNPMIVEVAQPVRYRYRIAAEFLIAI
MMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIAD
AAHQLRTPLTAIKLHAEQAAVARDPQQALTAVRELRSAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAALAFETGAEW
VPRALAAHVDLGFQRGDGRGDDEPLVVRGNPVLLREVIANLLDNALKYVPLARPQGARITMDVSRIALDEGHAAAEIVVE
DNGSGVPATQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYADAPEGGSCFIVRVPLADTPSTPAPPP
CESPAASA

Sequences:

>Translated_488_residues
MTSLRRTLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVVDRSLADLASAISKQIQIAGPDAPFTVPPLAQAMFSDPTEQL
IYRISDGEHELAGDPKLPLQGTSVRRMHVAYVFEAEYDNQAVRVAQVRVEQTESGNPMIVEVAQPVRYRYRIAAEFLIAI
MMPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIAD
AAHQLRTPLTAIKLHAEQAAVARDPQQALTAVRELRSAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAALAFETGAEW
VPRALAAHVDLGFQRGDGRGDDEPLVVRGNPVLLREVIANLLDNALKYVPLARPQGARITMDVSRIALDEGHAAAEIVVE
DNGSGVPATQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYADAPEGGSCFIVRVPLADTPSTPAPPP
CESPAASA
>Mature_487_residues
TSLRRTLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVVDRSLADLASAISKQIQIAGPDAPFTVPPLAQAMFSDPTEQLI
YRISDGEHELAGDPKLPLQGTSVRRMHVAYVFEAEYDNQAVRVAQVRVEQTESGNPMIVEVAQPVRYRYRIAAEFLIAIM
MPLLLLLLAGWGIVWRVVNQQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIADA
AHQLRTPLTAIKLHAEQAAVARDPQQALTAVRELRSAADRAVRLSNQLLSLARAEPGEQAARFVDVDLAALAFETGAEWV
PRALAAHVDLGFQRGDGRGDDEPLVVRGNPVLLREVIANLLDNALKYVPLARPQGARITMDVSRIALDEGHAAAEIVVED
NGSGVPATQQADLFKRFFRGDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYADAPEGGSCFIVRVPLADTPSTPAPPPC
ESPAASA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=322, Percent_Identity=32.2981366459627, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790551, Length=303, Percent_Identity=30.3630363036304, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786783, Length=341, Percent_Identity=26.3929618768328, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=27.0588235294118, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=293, Percent_Identity=27.3037542662116, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=275, Percent_Identity=30.5454545454545, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=26.5917602996255, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081816, Length=381, Percent_Identity=27.0341207349081, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=27.4247491638796, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082128, Length=322, Percent_Identity=27.639751552795, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=29.2490118577075, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=237, Percent_Identity=27.4261603375527, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52755; Mature: 52624

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLRRTLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVVDRSLADLASAISKQIQIAGPD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCC
APFTVPPLAQAMFSDPTEQLIYRISDGEHELAGDPKLPLQGTSVRRMHVAYVFEAEYDNQ
CCCCCCHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCC
AVRVAQVRVEQTESGNPMIVEVAQPVRYRYRIAAEFLIAIMMPLLLLLLAGWGIVWRVVN
CEEEHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIAD
HHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHQLRTPLTAIKLHAEQAAVARDPQQALTAVRELRSAADRAVRLSNQLLSLARAEPGEQ
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AARFVDVDLAALAFETGAEWVPRALAAHVDLGFQRGDGRGDDEPLVVRGNPVLLREVIAN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCCCEEEECCHHHHHHHHHH
LLDNALKYVPLARPQGARITMDVSRIALDEGHAAAEIVVEDNGSGVPATQQADLFKRFFR
HHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHC
GDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYADAPEGGSCFIVRVPLADTPSTPAPPP
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCC
CESPAASA
CCCCCCCC
>Mature Secondary Structure 
TSLRRTLLRRLAAPLSMLALMSGLIAYWLAWQYTQHVVDRSLADLASAISKQIQIAGPD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCC
APFTVPPLAQAMFSDPTEQLIYRISDGEHELAGDPKLPLQGTSVRRMHVAYVFEAEYDNQ
CCCCCCHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCC
AVRVAQVRVEQTESGNPMIVEVAQPVRYRYRIAAEFLIAIMMPLLLLLLAGWGIVWRVVN
CEEEHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQLGPLTHLADSLNRQTHTSLEPVDETEVPLEIRPLTSAMNALLGRLKTALDAQRKFIAD
HHHCHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
AAHQLRTPLTAIKLHAEQAAVARDPQQALTAVRELRSAADRAVRLSNQLLSLARAEPGEQ
HHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AARFVDVDLAALAFETGAEWVPRALAAHVDLGFQRGDGRGDDEPLVVRGNPVLLREVIAN
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEECCCCCCCCCCEEEECCHHHHHHHHHH
LLDNALKYVPLARPQGARITMDVSRIALDEGHAAAEIVVEDNGSGVPATQQADLFKRFFR
HHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHC
GDAQSGNGVETGAGLGLAIVHDIIAMHGGTVSYADAPEGGSCFIVRVPLADTPSTPAPPP
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCCC
CESPAASA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]