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The map label for this gene is atpA_1 [H]

Identifier: 237814347

GI number: 237814347

Start: 3974337

End: 3975878

Strand: Reverse

Name: atpA_1 [H]

Synonym: GBP346_A4145

Alternate gene names: 237814347

Gene position: 3975878-3974337 (Counterclockwise)

Preceding gene: 237814348

Following gene: 237814346

Centisome position: 97.01

GC content: 64.01

Gene sequence:

>1542_bases
ATGCAACTCAATCCCTCTGAGATCAGCGAGCTGATCAAGAGCCGGATCCAGGGCCTTGAAGCGAGCGCAGACGTTCGCAA
CCAGGGCACCGTGATCTCCGTGACCGACGGCATCGTGCGCATTCACGGCCTGTCGGACGTGATGCAGGGCGAAATGCTCG
AGTTCCCGGGCAACACGTTCGGCCTCGCGCTGAACCTCGAGCGCGACTCGGTCGGCGCGGTGATTCTCGGCGAATACGAA
CACATCTCGGAAGGCGACATCGTCAAGACGACGGGCCGCATTCTCGAAGTGCCGGTCGGCCCGGAACTCGTCGGCCGCGT
GGTCGACGCGCTCGGCAATCCGATCGACGGCAAGGGCCCGGTCAACGCGAAGCTGACCGACGCGATCGAGAAGATCGCCC
CGGGCGTGATCTGGCGCAAGTCGGTGTCGCAGCCGGTGCAGACGGGCCTGAAGTCGATCGACTCGATGGTGCCGATCGGC
CGGGGCCAGCGCGAGCTGATCATCGGCGACCGTCAGTGCGGCAAGACCGCGGTGGCGATCGACACGATCATCAACCAGAA
GGGCAAGGACCTCATCTGTATCTACGTCGCGATCGGCCAGAAGGCTTCGTCGATCATGAACGTGGTGCGCAAGCTCGAGG
AAACCGGCGCGCTCGAATACACGATCGTCGTCGCCGCGTCGGCGTCGGAATCGGCCGCGATGCAATACCTCGCGCCGTAC
GCCGGCTGCACGATGGGCGAATACTTCCGCGATCGCGGCCAGGACGCCCTCATCATTTACGACGACTTGACCAAGCAAGC
TTGGGCGTATCGTCAGATCTCGCTGCTGCTGCGCCGCCCGCCGGGCCGTGAAGCGTACCCGGGCGACGTGTTCTATCTGC
ACTCGCGCCTGCTCGAGCGTGCGGCTCGCGTGTCGGAAGAGTACGTCGAGAAATTCACGAACGGCGAAGTGAAGGGCAAG
AGCGGCTCGCTGACGGCGCTGCCCGTCATCGAAACGCAGGCAGGCGACGTGACCGCGTTCGTTCCGACGAACGTGATCTC
GATCACCGACGGCCAGATCTTCCTGGAAACCGACCTGTTCAACGCCGGTATCCGCCCCGCGATCAACGCGGGCGTATCGG
TGTCGCGAGTCGGCGGCGCCGCGCAGACGAAGGTCGTGAAGAAGCTGTCGGGCGGTATCCGTACCGACCTCGCGCAGTAT
CGCGAACTGGCCGCGTTCGCGCAGTTCGCGTCGGATCTCGACGAAGCGACCCGCAAGCAGCTCGAGCGCGGCCGCCGTGT
GACGGAGTTGCTCAAGCAGCCGCAATACCAGCCGCTGCAGGTGTGGGAGCTGGCCGTGTCGCTGTTCTCGGCGAACAACG
GCTATCTCGACGACCTCGACGTCAAGGACGTCCTGCCGTTCGAGAAGGGCCTGCGCGAGTATCTGAAGACGAGCCACGCT
GACCTCATCAAGCGCATCGAAGACACGAAGGACTTGTCGAAGGACGACGAGAGCGCGCTGCACGCCGCGCTCAAGGACTT
CAAGAAGTCCGGTGCCTATTGA

Upstream 100 bases:

>100_bases
GATACCTCGGTCCGCGCGCGGCTCGCCGGCATGCAGGCGGCGCTGACCGCTTGAGCGAGCGCAGCCGGCACGCAACAGAA
TTGAAAATCAGGAGCGAATA

Downstream 100 bases:

>100_bases
TCCGCGAGGGACACCTTGAAGCGGCGCGGGCCGCGTAACGCGCCCGCGCCGCTTCGGTCAAGGAGCAAGCAATGGCTGGA
ATGAAGGAAATTCGCGGCAA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHA
DLIKRIEDTKDLSKDDESALHAALKDFKKSGAY

Sequences:

>Translated_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHA
DLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
>Mature_513_residues
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTFGLALNLERDSVGAVILGEYE
HISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGPVNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIG
RGQRELIIGDRQCGKTAVAIDTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPY
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGEVKGK
SGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLFNAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQY
RELAAFAQFASDLDEATRKQLERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHA
DLIKRIEDTKDLSKDDESALHAALKDFKKSGAY

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=56.8627450980392, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=56.8627450980392, Blast_Score=586, Evalue=1e-167,
Organism=Homo sapiens, GI32189394, Length=453, Percent_Identity=24.5033112582781, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI19913428, Length=308, Percent_Identity=27.2727272727273, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI19913426, Length=313, Percent_Identity=25.8785942492013, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI19913424, Length=319, Percent_Identity=26.6457680250784, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=69.3957115009747, Blast_Score=732, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=281, Percent_Identity=28.4697508896797, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790170, Length=377, Percent_Identity=24.4031830238727, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=510, Percent_Identity=56.4705882352941, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988080, Length=510, Percent_Identity=56.4705882352941, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71988074, Length=510, Percent_Identity=52.156862745098, Blast_Score=523, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI25144756, Length=453, Percent_Identity=24.2825607064018, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=382, Percent_Identity=24.6073298429319, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17570191, Length=314, Percent_Identity=27.0700636942675, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17565854, Length=378, Percent_Identity=25.3968253968254, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=72, Percent_Identity=40.2777777777778, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319370, Length=511, Percent_Identity=55.3816046966732, Blast_Score=578, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6322581, Length=426, Percent_Identity=26.056338028169, Blast_Score=123, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6319603, Length=382, Percent_Identity=27.2251308900524, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24658560, Length=510, Percent_Identity=57.0588235294118, Blast_Score=583, Evalue=1e-166,
Organism=Drosophila melanogaster, GI281361666, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646341, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136796, Length=316, Percent_Identity=26.2658227848101, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24638766, Length=414, Percent_Identity=24.6376811594203, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574560, Length=436, Percent_Identity=23.6238532110092, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24583988, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583986, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583984, Length=248, Percent_Identity=28.2258064516129, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583992, Length=319, Percent_Identity=26.3322884012539, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129479, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55912; Mature: 55912

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAI
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
DLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNPSEISELIKSRIQGLEASADVRNQGTVISVTDGIVRIHGLSDVMQGEMLEFPGNTF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEEECHHHHHCCCCEECCCCEE
GLALNLERDSVGAVILGEYEHISEGDIVKTTGRILEVPVGPELVGRVVDALGNPIDGKGP
EEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEEECCCCHHHHHHHHHHHCCCCCCCCC
VNAKLTDAIEKIAPGVIWRKSVSQPVQTGLKSIDSMVPIGRGQRELIIGDRQCGKTAVAI
CCCHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DTIINQKGKDLICIYVAIGQKASSIMNVVRKLEETGALEYTIVVAASASESAAMQYLAPY
HHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHH
AGCTMGEYFRDRGQDALIIYDDLTKQAWAYRQISLLLRRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AARVSEEYVEKFTNGEVKGKSGSLTALPVIETQAGDVTAFVPTNVISITDGQIFLETDLF
HHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCEEEEECCCEEEEECCEEEEEECHH
NAGIRPAINAGVSVSRVGGAAQTKVVKKLSGGIRTDLAQYRELAAFAQFASDLDEATRKQ
CCCCCHHHHCCCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LERGRRVTELLKQPQYQPLQVWELAVSLFSANNGYLDDLDVKDVLPFEKGLREYLKTSHA
HHHCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
DLIKRIEDTKDLSKDDESALHAALKDFKKSGAY
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA