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The map label for this gene is aidB [H]

Identifier: 237814331

GI number: 237814331

Start: 3954103

End: 3955743

Strand: Direct

Name: aidB [H]

Synonym: GBP346_A4129

Alternate gene names: 237814331

Gene position: 3954103-3955743 (Clockwise)

Preceding gene: 237814323

Following gene: 237814332

Centisome position: 96.48

GC content: 71.12

Gene sequence:

>1641_bases
ATGGCCTGGTCGACCCACGAGGTGAGCAACCAGTTCGACGAACTGACCGACTATAACCTCTTCGCCACCGACCCGGCGCT
CGGCGAAGCGCTCGAACGCGCGGGCGCGTCGTGGGCCGCGCCGCGGCTCGACGCGTTCGGCGCGCGGCTCGGCACGCGCG
ACATCGCGCGGCTGGCCGAGGACGCGAACCGTCACGTGCCCGAGCTGAATGCGTTCGACCGCCGCGGCCGCCGCATCGAC
CGCGTGGACTTCCACCCGAGCTGGCACGCGCTCCTCGGTCTGTATCGCGAACAGGGCCTGATCTCGCTCGCGTTCCGCGA
ATCGCGCGCCGGCCGCTGGGCGGCGAACGCGGCGGGCTTCTACCTGCACGGCCAGATCGAGGCGGGCACGCTGTGCCCGG
CAACGATGACGCAGGCGAGCATTCCCGTTCTGCAGAAGGAGCCCGCGCTGTGGGCGCAATTGAAAGACAAGCTCTACAGC
GACGCCCACGATCCGCGCGACGCGCCGATCGGCGCGAAGCAGTCGATCATGATCGGCATGGGCATGACCGAAAAGCAGGG
CGGCTCGGACGTGCGCGCGAACACGACGCTCGCCGTGCCCGTCGGCGCGGGCGGCCGCGGCGGCGAGCATCTGCTGCGCG
GCCACAAATGGTTCTTCTCCGCGCCGATGTGCGACGCGCATCTCGTCGTCGCGCGCACCGAAGCGGGCGGCCCGTCGTGC
TTCTACGTGCCGCGCTGGCGGCCGGACGGCACGAAGAACGCGGTGCGCATCCAGCGGCTGAAGAACAAGGTCGGCAACCG
CAGCAATTCGAGCAGCGAAATCGAACTCGACGACGCATGGGGCGTGATGCTCGGCGAAGAAGGACGCGGCATTCCGACGA
TCATCGAGATGGCCACCTACACGCGCCTGAACTGCGTGCTCGGCAGCGCGGCGATCCTGCGCCAGGGGCTCGTTCAGGCG
ATCGCGTACACGCGGCAGCGTCACGCGTTCGGCCGCGCGCTCGCCGAGCAGCCGCTGATGCGCGCGGTGCTCGCCGATCT
CGCGCTCGAAAGCGAAGCGGCGCTCGCGCTTGCGATGCGGCTCGCGCAGGCGTTCGAGCGCGGCGAGCCGGCGTGGACGC
GCATCGTCGCGCCGGCCGCGAAATTCTGGGTCTGCAAGCGCGCGGTCGAGGCGGCGGGCGAAGTAATGGAGATATTCGGC
GGCAACGGCTACGTCGACGACGGTCCGATCGCGCGGCTGTTTCGCGAGGCGCCCGTCAATTCGATCTGGGAAGGTTCCGG
CAACGTGATGTGTCTCGACGTGATGCGCGCGATCTCACGCGAGCCGGACGCGGCGCACGCGCTCATCGACGAGTTGCACG
CGCTCGGCGGCCGCGATGCGCGGATCCGCGCGGAACTCGACGCGCTGCGCGCGCAGCTCGGCACGCCGCCCGATGCGCTC
GAAGCGCTCGGCCGCGTGCTCGCGCAGCGCATCGCGCTGCTCGCGCAGGCGTGCCTGCTGAGCGACGCGGCGCCTGCCGT
CGTGAGCGACGGCTTCATCGCGACGCGCTTCGGCGAGCCCGCGTGGGGCCGCGTGACGGGCGCGCTCGATGCGCGGCGCG
TCGACGCCGCCGCACTGCTGCAGCGCGCGTACGCCGCGTAG

Upstream 100 bases:

>100_bases
CGCAATCGATTTGTCGGGCGGCGCCGAAACCTGAACATGTCGCGAAGTCATCTTTGCTAACCTGATCGAGCCGAACAACG
ACAAGAAGGAGACGCCCATC

Downstream 100 bases:

>100_bases
GCGCGCCGCGCGCATGGCGGCTTGCCCGCGCCCGGCCGCGCCGATTGCGTCGAAGCCGGGCGCGGCGCGCCGCCGCCCCC
AATGATCGCCTGCTGCAACG

Product: protein AidB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MAWSTHEVSNQFDELTDYNLFATDPALGEALERAGASWAAPRLDAFGARLGTRDIARLAEDANRHVPELNAFDRRGRRID
RVDFHPSWHALLGLYREQGLISLAFRESRAGRWAANAAGFYLHGQIEAGTLCPATMTQASIPVLQKEPALWAQLKDKLYS
DAHDPRDAPIGAKQSIMIGMGMTEKQGGSDVRANTTLAVPVGAGGRGGEHLLRGHKWFFSAPMCDAHLVVARTEAGGPSC
FYVPRWRPDGTKNAVRIQRLKNKVGNRSNSSSEIELDDAWGVMLGEEGRGIPTIIEMATYTRLNCVLGSAAILRQGLVQA
IAYTRQRHAFGRALAEQPLMRAVLADLALESEAALALAMRLAQAFERGEPAWTRIVAPAAKFWVCKRAVEAAGEVMEIFG
GNGYVDDGPIARLFREAPVNSIWEGSGNVMCLDVMRAISREPDAAHALIDELHALGGRDARIRAELDALRAQLGTPPDAL
EALGRVLAQRIALLAQACLLSDAAPAVVSDGFIATRFGEPAWGRVTGALDARRVDAAALLQRAYAA

Sequences:

>Translated_546_residues
MAWSTHEVSNQFDELTDYNLFATDPALGEALERAGASWAAPRLDAFGARLGTRDIARLAEDANRHVPELNAFDRRGRRID
RVDFHPSWHALLGLYREQGLISLAFRESRAGRWAANAAGFYLHGQIEAGTLCPATMTQASIPVLQKEPALWAQLKDKLYS
DAHDPRDAPIGAKQSIMIGMGMTEKQGGSDVRANTTLAVPVGAGGRGGEHLLRGHKWFFSAPMCDAHLVVARTEAGGPSC
FYVPRWRPDGTKNAVRIQRLKNKVGNRSNSSSEIELDDAWGVMLGEEGRGIPTIIEMATYTRLNCVLGSAAILRQGLVQA
IAYTRQRHAFGRALAEQPLMRAVLADLALESEAALALAMRLAQAFERGEPAWTRIVAPAAKFWVCKRAVEAAGEVMEIFG
GNGYVDDGPIARLFREAPVNSIWEGSGNVMCLDVMRAISREPDAAHALIDELHALGGRDARIRAELDALRAQLGTPPDAL
EALGRVLAQRIALLAQACLLSDAAPAVVSDGFIATRFGEPAWGRVTGALDARRVDAAALLQRAYAA
>Mature_545_residues
AWSTHEVSNQFDELTDYNLFATDPALGEALERAGASWAAPRLDAFGARLGTRDIARLAEDANRHVPELNAFDRRGRRIDR
VDFHPSWHALLGLYREQGLISLAFRESRAGRWAANAAGFYLHGQIEAGTLCPATMTQASIPVLQKEPALWAQLKDKLYSD
AHDPRDAPIGAKQSIMIGMGMTEKQGGSDVRANTTLAVPVGAGGRGGEHLLRGHKWFFSAPMCDAHLVVARTEAGGPSCF
YVPRWRPDGTKNAVRIQRLKNKVGNRSNSSSEIELDDAWGVMLGEEGRGIPTIIEMATYTRLNCVLGSAAILRQGLVQAI
AYTRQRHAFGRALAEQPLMRAVLADLALESEAALALAMRLAQAFERGEPAWTRIVAPAAKFWVCKRAVEAAGEVMEIFGG
NGYVDDGPIARLFREAPVNSIWEGSGNVMCLDVMRAISREPDAAHALIDELHALGGRDARIRAELDALRAQLGTPPDALE
ALGRVLAQRIALLAQACLLSDAAPAVVSDGFIATRFGEPAWGRVTGALDARRVDAAALLQRAYAA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=270, Percent_Identity=25.5555555555556, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI226958414, Length=270, Percent_Identity=25.1851851851852, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI4501859, Length=268, Percent_Identity=25.7462686567164, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4557233, Length=261, Percent_Identity=27.9693486590038, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557231, Length=272, Percent_Identity=23.8970588235294, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI187960098, Length=272, Percent_Identity=23.8970588235294, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4501857, Length=273, Percent_Identity=27.1062271062271, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7656849, Length=270, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI87082384, Length=514, Percent_Identity=46.3035019455253, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1786223, Length=263, Percent_Identity=25.0950570342205, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081958, Length=266, Percent_Identity=24.812030075188, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI86563383, Length=501, Percent_Identity=30.1397205588822, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI86563381, Length=501, Percent_Identity=30.1397205588822, Blast_Score=180, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17538396, Length=273, Percent_Identity=26.3736263736264, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=270, Percent_Identity=26.2962962962963, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=271, Percent_Identity=27.3062730627306, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17569725, Length=280, Percent_Identity=24.2857142857143, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=268, Percent_Identity=25, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=328, Percent_Identity=27.1341463414634, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17533517, Length=269, Percent_Identity=23.4200743494424, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17551932, Length=328, Percent_Identity=25, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21356377, Length=268, Percent_Identity=27.2388059701493, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646207, Length=268, Percent_Identity=26.4925373134328, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24660351, Length=270, Percent_Identity=28.5185185185185, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355753, Length=317, Percent_Identity=23.0283911671924, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363737, Length=283, Percent_Identity=22.9681978798587, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666513, Length=269, Percent_Identity=24.907063197026, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59120; Mature: 58989

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWSTHEVSNQFDELTDYNLFATDPALGEALERAGASWAAPRLDAFGARLGTRDIARLAE
CCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHH
DANRHVPELNAFDRRGRRIDRVDFHPSWHALLGLYREQGLISLAFRESRAGRWAANAAGF
HHHCCCCCCCHHHHCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEHHCCCCCEECCCCCE
YLHGQIEAGTLCPATMTQASIPVLQKEPALWAQLKDKLYSDAHDPRDAPIGAKQSIMIGM
EEEEEECCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GMTEKQGGSDVRANTTLAVPVGAGGRGGEHLLRGHKWFFSAPMCDAHLVVARTEAGGPSC
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEECCCCCCEEEEEEECCCCCEE
FYVPRWRPDGTKNAVRIQRLKNKVGNRSNSSSEIELDDAWGVMLGEEGRGIPTIIEMATY
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHH
TRLNCVLGSAAILRQGLVQAIAYTRQRHAFGRALAEQPLMRAVLADLALESEAALALAMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LAQAFERGEPAWTRIVAPAAKFWVCKRAVEAAGEVMEIFGGNGYVDDGPIARLFREAPVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
SIWEGSGNVMCLDVMRAISREPDAAHALIDELHALGGRDARIRAELDALRAQLGTPPDAL
HHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHH
EALGRVLAQRIALLAQACLLSDAAPAVVSDGFIATRFGEPAWGRVTGALDARRVDAAALL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHH
QRAYAA
HHHHCC
>Mature Secondary Structure 
AWSTHEVSNQFDELTDYNLFATDPALGEALERAGASWAAPRLDAFGARLGTRDIARLAE
CCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHH
DANRHVPELNAFDRRGRRIDRVDFHPSWHALLGLYREQGLISLAFRESRAGRWAANAAGF
HHHCCCCCCCHHHHCCCCCCCEECCCCHHHHHHHHHHCCCEEEEEHHCCCCCEECCCCCE
YLHGQIEAGTLCPATMTQASIPVLQKEPALWAQLKDKLYSDAHDPRDAPIGAKQSIMIGM
EEEEEECCCCCCCHHHHHHCCCCHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
GMTEKQGGSDVRANTTLAVPVGAGGRGGEHLLRGHKWFFSAPMCDAHLVVARTEAGGPSC
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEECCCCCCEEEEEEECCCCCEE
FYVPRWRPDGTKNAVRIQRLKNKVGNRSNSSSEIELDDAWGVMLGEEGRGIPTIIEMATY
EECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCCCCCHHHHHHHHH
TRLNCVLGSAAILRQGLVQAIAYTRQRHAFGRALAEQPLMRAVLADLALESEAALALAMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
LAQAFERGEPAWTRIVAPAAKFWVCKRAVEAAGEVMEIFGGNGYVDDGPIARLFREAPVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
SIWEGSGNVMCLDVMRAISREPDAAHALIDELHALGGRDARIRAELDALRAQLGTPPDAL
HHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHH
EALGRVLAQRIALLAQACLLSDAAPAVVSDGFIATRFGEPAWGRVTGALDARRVDAAALL
HHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCEEEECCCCCCCCHHHCCHHHHHHHHHHHH
QRAYAA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]