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The map label for this gene is fabH [H]

Identifier: 237814267

GI number: 237814267

Start: 3893323

End: 3894357

Strand: Direct

Name: fabH [H]

Synonym: GBP346_A4062

Alternate gene names: 237814267

Gene position: 3893323-3894357 (Clockwise)

Preceding gene: 237814266

Following gene: 237814268

Centisome position: 94.99

GC content: 68.21

Gene sequence:

>1035_bases
ATGACACCGGCCGCCCATCCGCCGCGCGCGGCGATCGCGGACATCGCCGGGCATCTGCCCGAGCAGGTGCTGACGAACGA
CGTCCTCGCGCAGCTCTATCCGGACTGGCCGGCGGAGAAGATCCTCGCGAAGACGGGCATCCGCGAACGCCGCATCGCCG
CTCCCCGCGAGACGGCCGCCGACCTCGCGTATGAAGCGGCGCGCAAGCTGTTCGCGCAAGGCGCCGTCGGCGCAGACCAG
GTCGATTTCGTGATTCTCTGCACGCAGGCGCCCGACTACGTGCTGCCCACGTCCGCCTGCATGCTCCAGCATCGCCTCGG
CATTCCGACGCACGCGGGGGCGCTCGACGTCAACCTCGGCTGCTCGGGTTACGTGTACGGGCTGTCGCTCGCGAAGGGGC
TCGTCGAGACGGGCGCCGCGCGCTGCGTGCTGCTGCTCACGGCCGACACCTATTCGAAGTATCTGCACCCGCTCGACAAG
AGCGTGCGCACGCTGTTCGGCGACGGCGCGAGCGCGACCGCCGTGATCGCCGAACACGGCGAGCTCGAGCGTATCGGCCC
CTTCGTGTTCGGCACGGACGGCCGCGGCGCACCGAACCTGATCGTGAAGGCGGGCCTCTTTCGCGAACCGAAGAGCGCCG
ACAGCGCGCGCGAGCACGAGGACGCATCGGGCAACGTGCGCACCGACGAGCATCTGTACATGAACGGCGCGGAGGTGATG
GCGTTCTCGCTCGCCGAAGTGCCGCGCGCCGCCGACCGGCTGCTCGCGCTCGCGGGCGAGCCGCGCGAGAACATCGATTG
CTTCGTGCTGCATCAGGCGAACCGCTTCATGCTCGATGCGCTGCGCAAGAAAATGAAGATCCCCGAACACAAATTCCCCG
TGCTGATGGAGCACTGCGGCAATACCGTCTCGTCGACACTGCCGCTCGCGCTCGAGACGATGCGGGCAAACGGCACGCTC
GCGCGCGGCATGCGTCTGATGCTGCTGGGATTCGGCGTCGGCTACTCCTGGGCCGGCTGCCTCGTGAACTTTTAG

Upstream 100 bases:

>100_bases
CCGCCGACGCCGCCGCGCGCGTGCTGTGCCTGCCGATCTATCCGGCGCTGTCCGATGCATCGCTCGAGCGAATCGTATCG
CTGATGGCGGGAGCGCATGC

Downstream 100 bases:

>100_bases
AAGGAACGGTGATGAACGCATTCTACGAAGGCCTCGCGGAAATCTTCGAGATCGACGCGAGCGAAGTCACGCCCGCGCTC
GCGCTCGGCGAGCACAACTG

Product: 3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTPAAHPPRAAIADIAGHLPEQVLTNDVLAQLYPDWPAEKILAKTGIRERRIAAPRETAADLAYEAARKLFAQGAVGADQ
VDFVILCTQAPDYVLPTSACMLQHRLGIPTHAGALDVNLGCSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDK
SVRTLFGDGASATAVIAEHGELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDASGNVRTDEHLYMNGAEVM
AFSLAEVPRAADRLLALAGEPRENIDCFVLHQANRFMLDALRKKMKIPEHKFPVLMEHCGNTVSSTLPLALETMRANGTL
ARGMRLMLLGFGVGYSWAGCLVNF

Sequences:

>Translated_344_residues
MTPAAHPPRAAIADIAGHLPEQVLTNDVLAQLYPDWPAEKILAKTGIRERRIAAPRETAADLAYEAARKLFAQGAVGADQ
VDFVILCTQAPDYVLPTSACMLQHRLGIPTHAGALDVNLGCSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDK
SVRTLFGDGASATAVIAEHGELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDASGNVRTDEHLYMNGAEVM
AFSLAEVPRAADRLLALAGEPRENIDCFVLHQANRFMLDALRKKMKIPEHKFPVLMEHCGNTVSSTLPLALETMRANGTL
ARGMRLMLLGFGVGYSWAGCLVNF
>Mature_343_residues
TPAAHPPRAAIADIAGHLPEQVLTNDVLAQLYPDWPAEKILAKTGIRERRIAAPRETAADLAYEAARKLFAQGAVGADQV
DFVILCTQAPDYVLPTSACMLQHRLGIPTHAGALDVNLGCSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDKS
VRTLFGDGASATAVIAEHGELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDASGNVRTDEHLYMNGAEVMA
FSLAEVPRAADRLLALAGEPRENIDCFVLHQANRFMLDALRKKMKIPEHKFPVLMEHCGNTVSSTLPLALETMRANGTLA
RGMRLMLLGFGVGYSWAGCLVNF

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=32.4159021406728, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37060; Mature: 36929

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAAHPPRAAIADIAGHLPEQVLTNDVLAQLYPDWPAEKILAKTGIRERRIAAPRETAA
CCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCCCHHHHH
DLAYEAARKLFAQGAVGADQVDFVILCTQAPDYVLPTSACMLQHRLGIPTHAGALDVNLG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEECC
CSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGASATAVIAEHG
CCHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDASGNVRTDEHLYMNGAEVM
CHHHHCCEEECCCCCCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCHHHH
AFSLAEVPRAADRLLALAGEPRENIDCFVLHQANRFMLDALRKKMKIPEHKFPVLMEHCG
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHCC
NTVSSTLPLALETMRANGTLARGMRLMLLGFGVGYSWAGCLVNF
CHHHHHHHHHHHHHHCCCHHHHHHHEEHHHHCCCHHHHHHEECC
>Mature Secondary Structure 
TPAAHPPRAAIADIAGHLPEQVLTNDVLAQLYPDWPAEKILAKTGIRERRIAAPRETAA
CCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHCCCCHHHHH
DLAYEAARKLFAQGAVGADQVDFVILCTQAPDYVLPTSACMLQHRLGIPTHAGALDVNLG
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEECC
CSGYVYGLSLAKGLVETGAARCVLLLTADTYSKYLHPLDKSVRTLFGDGASATAVIAEHG
CCHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ELERIGPFVFGTDGRGAPNLIVKAGLFREPKSADSAREHEDASGNVRTDEHLYMNGAEVM
CHHHHCCEEECCCCCCCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCHHHH
AFSLAEVPRAADRLLALAGEPRENIDCFVLHQANRFMLDALRKKMKIPEHKFPVLMEHCG
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHCC
NTVSSTLPLALETMRANGTLARGMRLMLLGFGVGYSWAGCLVNF
CHHHHHHHHHHHHHHCCCHHHHHHHEEHHHHCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]