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The map label for this gene is guaA [H]

Identifier: 237814259

GI number: 237814259

Start: 3884691

End: 3885299

Strand: Direct

Name: guaA [H]

Synonym: GBP346_A4054

Alternate gene names: 237814259

Gene position: 3884691-3885299 (Clockwise)

Preceding gene: 237814256

Following gene: 237814260

Centisome position: 94.78

GC content: 65.35

Gene sequence:

>609_bases
ATGCCAAAGCAGGGACGCTGCAGTTGGGTGAAAACCGAAGCGGACGCTCACTATCACGATACCGAGTGGGGTGTGCCGTC
GCGCGACGACCGGCATTTATTCGAAATGCTCGTACTCGAAGGCGCGCAGGCCGGCCTGTCGTGGTCGACGATCTTGAACA
AGCGCGCCGGCTACCGCGCGGCGTTCGCCGGCTTCGATATCGACGAGGTCGCCCGGTTCACGCCGAAGCGGATCGACGAG
CTGATGCTCGATGCGAGCATCGTGCGCAATCGCGCGAAGATCGAAGCCGCCGTTGCGAACGCGCGCGCGGTCCAGCAGAT
TCGCGCGGAACACGGCTCGCTCGCCGCGTTCCTGTGGTCGTTCGTCGATCATTCGCCGCTGCAGAACGCGTGGGCGTCGT
ATCGCGACGCGCCTGCGTCGACCGAGCGTTCGGACGCGCTCAGCCAGGCGCTCAAGCGCTACGGCTGCAAGTTCGTCGGC
TCGACGATCTGCTATGCGTTGATGCAGGCGACGGGGATGGTCAACGACCACGAAAGTACCTGCCCGTGCCATGCGCGCTG
TGCGGCGCTGGGCGAAAAGGCCCGCCGAAGGAAGAAGCCGGCGGCCTGA

Upstream 100 bases:

>100_bases
TAACCGCAACGACTCGCCTCGCCCATCAGCCGAACGGCCAGGCTTGCGCGCGCCGGCCGATCCGTTATGCTGACGCGACC
AGATCGACGGAACATGCGCC

Downstream 100 bases:

>100_bases
CGCGGACGCGCGGCGCGCCTCGGCAATCGGCGTCGCCGCGACGATCGGCCGGATTCGAAGGGCCACGCGCGCCGTGCGCG
TGGATCGGCAGCCCGACGAG

Product: DNA-3-methyladenine glycosylase 1

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPKQGRCSWVKTEADAHYHDTEWGVPSRDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFAGFDIDEVARFTPKRIDE
LMLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHSPLQNAWASYRDAPASTERSDALSQALKRYGCKFVG
STICYALMQATGMVNDHESTCPCHARCAALGEKARRRKKPAA

Sequences:

>Translated_202_residues
MPKQGRCSWVKTEADAHYHDTEWGVPSRDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFAGFDIDEVARFTPKRIDE
LMLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHSPLQNAWASYRDAPASTERSDALSQALKRYGCKFVG
STICYALMQATGMVNDHESTCPCHARCAALGEKARRRKKPAA
>Mature_201_residues
PKQGRCSWVKTEADAHYHDTEWGVPSRDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRAAFAGFDIDEVARFTPKRIDEL
MLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWSFVDHSPLQNAWASYRDAPASTERSDALSQALKRYGCKFVGS
TICYALMQATGMVNDHESTCPCHARCAALGEKARRRKKPAA

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=49.4444444444444, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 22441; Mature: 22309

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQGRCSWVKTEADAHYHDTEWGVPSRDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRA
CCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHH
AFAGFDIDEVARFTPKRIDELMLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWS
HHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDHSPLQNAWASYRDAPASTERSDALSQALKRYGCKFVGSTICYALMQATGMVNDHEST
HHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
CPCHARCAALGEKARRRKKPAA
CCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKQGRCSWVKTEADAHYHDTEWGVPSRDDRHLFEMLVLEGAQAGLSWSTILNKRAGYRA
CCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHH
AFAGFDIDEVARFTPKRIDELMLDASIVRNRAKIEAAVANARAVQQIRAEHGSLAAFLWS
HHCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVDHSPLQNAWASYRDAPASTERSDALSQALKRYGCKFVGSTICYALMQATGMVNDHEST
HHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
CPCHARCAALGEKARRRKKPAA
CCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]